ATE168724T1 - Nachweis eines polynukleotids durch ersätzung einer kette an einer fangsonde - Google Patents

Nachweis eines polynukleotids durch ersätzung einer kette an einer fangsonde

Info

Publication number
ATE168724T1
ATE168724T1 AT95108635T AT95108635T ATE168724T1 AT E168724 T1 ATE168724 T1 AT E168724T1 AT 95108635 T AT95108635 T AT 95108635T AT 95108635 T AT95108635 T AT 95108635T AT E168724 T1 ATE168724 T1 AT E168724T1
Authority
AT
Austria
Prior art keywords
polynucleotide
capture probe
support
nucleic acid
label
Prior art date
Application number
AT95108635T
Other languages
English (en)
Inventor
Michael S Urdea
Original Assignee
Chiron Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/251,152 external-priority patent/US5118605A/en
Application filed by Chiron Corp filed Critical Chiron Corp
Application granted granted Critical
Publication of ATE168724T1 publication Critical patent/ATE168724T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/6823—Release of bound markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AT95108635T 1988-09-29 1988-10-03 Nachweis eines polynukleotids durch ersätzung einer kette an einer fangsonde ATE168724T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/251,152 US5118605A (en) 1984-10-16 1988-09-29 Polynucleotide determination with selectable cleavage sites

Publications (1)

Publication Number Publication Date
ATE168724T1 true ATE168724T1 (de) 1998-08-15

Family

ID=22950701

Family Applications (2)

Application Number Title Priority Date Filing Date
AT88309203T ATE133714T1 (de) 1988-09-29 1988-10-03 Polynukleotid-bestimmung mit selektierbaren spaltstellen
AT95108635T ATE168724T1 (de) 1988-09-29 1988-10-03 Nachweis eines polynukleotids durch ersätzung einer kette an einer fangsonde

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT88309203T ATE133714T1 (de) 1988-09-29 1988-10-03 Polynukleotid-bestimmung mit selektierbaren spaltstellen

Country Status (3)

Country Link
EP (1) EP0703296B1 (de)
AT (2) ATE133714T1 (de)
DE (1) DE3856224T2 (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5824478A (en) * 1996-04-30 1998-10-20 Vysis, Inc. Diagnostic methods and probes
ATE335845T1 (de) 1997-05-16 2006-09-15 Exact Sciences Corp Elektrophoretische analyse von molekülen mit immobilisierten sonden
AU1384299A (en) 1997-11-06 1999-05-31 Mosaic Technologies Multiple sequential polynucleotide displacement reactions for signal amplification and processing
US6287772B1 (en) 1998-04-29 2001-09-11 Boston Probes, Inc. Methods, kits and compositions for detecting and quantitating target sequences
WO1999066078A1 (en) 1998-06-18 1999-12-23 Mosaic Technologies Denaturing gradient affinity electrophoresis and methods of use thereof
WO2000020643A1 (en) 1998-10-05 2000-04-13 Mosaic Technologies Reverse displacement assay for detection of nucleic acid sequences
US7439016B1 (en) 2000-06-15 2008-10-21 Digene Corporation Detection of nucleic acids by type-specific hybrid capture method
US7601497B2 (en) 2000-06-15 2009-10-13 Qiagen Gaithersburg, Inc. Detection of nucleic acids by target-specific hybrid capture method
AU2003242605A1 (en) * 2002-06-03 2003-12-19 Pamgene B.V. Novel high density arrays and methods for analyte analysis
US7340957B2 (en) 2004-07-29 2008-03-11 Los Alamos National Security, Llc Ultrasonic analyte concentration and application in flow cytometry
EP2664916B1 (de) 2007-04-02 2017-02-08 Acoustic Cytometry Systems, Inc. Verfahren zum Manipulieren einer Flüssigkeit in einer Durchflusszelle unter Anwendung von akustischer Fokussierung
US8266951B2 (en) 2007-12-19 2012-09-18 Los Alamos National Security, Llc Particle analysis in an acoustic cytometer
TWI419974B (zh) 2008-10-27 2013-12-21 Qiagen Gaithersburg Inc 於自動平台上之快速結果雜交捕捉法
WO2010127228A1 (en) 2009-05-01 2010-11-04 Qiagen Gaithersburg, Inc. A non-target amplification method for detection of rna splice-forms in a sample
JP5826752B2 (ja) 2009-09-14 2015-12-02 キアジェン ゲイサーズバーグ インコーポレイテッド 細胞学用培地に固定された組織サンプルから核酸またはタンパク質を回収するための組成物および方法
JP2013517803A (ja) 2010-01-29 2013-05-20 キアジェン ゲイサーズバーグ インコーポレイテッド サンプル中のｈｐｖの存在を決定および確認する方法
CA2787924A1 (en) 2010-01-29 2011-08-04 Qiagen Gaithersburg, Inc. Methods and compositions for sequence-specific purification and multiplex analysis of nucleic acids
EP2572001A2 (de) 2010-05-19 2013-03-27 QIAGEN Gaithersburg, Inc. Verfahren und zusammensetzungen für sequenzspezifische reinigung und multiplex-analyse von nukleinsäuren
JP6153866B2 (ja) 2010-05-25 2017-06-28 キアゲン ガイサーズバーグ アイエヌシー． 迅速なハイブリッド捕捉アッセイ、及び関連する戦略的に切断されたプローブ
WO2012116220A2 (en) 2011-02-24 2012-08-30 Qiagen Gaithersburg, Inc. Materials and methods for detection of hpv nucleic acid
SG11202009802WA (en) 2018-04-03 2020-11-27 The Royal Institution For The Advancement Of Learning/Mcgill Univ Colocalization-by-linkage sandwich assays
CN115380218A (zh) 2019-10-02 2022-11-22 诺米克生物公司 用于多重化的连接-共定位夹心测定

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL154598B (nl) 1970-11-10 1977-09-15 Organon Nv Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking.
US3853914A (en) 1971-01-11 1974-12-10 Syva Co Ligand determination of spin labeled compounds by receptor displacement
US4174384A (en) 1975-06-30 1979-11-13 Syva Company Fluorescence quenching with immunological pairs in immunoassays
IT1079045B (it) 1977-05-16 1985-05-08 Syva Co Analisi imuunologica fluorescente a doppio ricettore
US4160645A (en) 1977-07-14 1979-07-10 Syva Company Catalyst mediated competitive protein binding assay
US4277437A (en) 1978-04-05 1981-07-07 Syva Company Kit for carrying out chemically induced fluorescence immunoassay
US4318890A (en) 1978-10-02 1982-03-09 Monahan Daniel E Reactor for generating granular metal hydride
US4318707A (en) 1978-11-24 1982-03-09 Syva Company Macromolecular fluorescent quencher particle in specific receptor assays
US4358535A (en) 1980-12-08 1982-11-09 Board Of Regents Of The University Of Washington Specific DNA probes in diagnostic microbiology
FR2519005B1 (fr) 1981-12-29 1985-10-25 Pasteur Institut Fragments d'adn marques a l'une au moins de leurs extremites par des ribonucleotides modifies reconnaissables par des molecules affines et procede pour realiser une analyse de tels fragments d'adn
US4766064A (en) * 1984-05-07 1988-08-23 Allied Corporation Displacement polynucleotide assay employing polyether and diagnostic kit
US4868105A (en) 1985-12-11 1989-09-19 Chiron Corporation Solution phase nucleic acid sandwich assay
EP0286642A4 (de) * 1985-12-17 1990-06-27 Genetics Inst Testverfahren mittels polynukleotiden versetzung und reagenzkomplex.
WO1988001302A1 (en) * 1986-08-11 1988-02-25 Siska Diagnostics, Inc. Nucleic acid probe assay methods and compositions
ATE66695T1 (de) * 1986-12-01 1991-09-15 Molecular Biosystems Inc Verfahren zur erhoehung der empfindlichkeit von nukleinsaeure-hybridisierungstesten.

Also Published As

Publication number Publication date
DE3856224T2 (de) 1998-12-03
EP0703296A1 (de) 1996-03-27
EP0703296B1 (de) 1998-07-22
DE3856224D1 (de) 1998-08-27
ATE133714T1 (de) 1996-02-15

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