DK0609310T3 - N-(mercaptoacyl)aminosyrer, fremgangsmåder til fremstilling og terapeutisk anvendelse deraf og farmaceutiske sammensætninge - Google Patents

N-(mercaptoacyl)aminosyrer, fremgangsmåder til fremstilling og terapeutisk anvendelse deraf og farmaceutiske sammensætninge

Info

Publication number: DK0609310T3
Authority: DK; Denmark
Prior art keywords: radical; aryl; preparation; methods; pharmaceutical compositions
Prior art date: 1991-10-25

Application number

DK92921688T

Other languages

English (en)

Inventor

Marie-Claude Fournie-Zaluski

Bernard Pierre Roques

Original Assignee

Inst Nat Sante Rech Med

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-10-25

Filing date

1992-10-21

Publication date

1999-04-26

1992-10-21 Application filed by Inst Nat Sante Rech Med filed Critical Inst Nat Sante Rech Med

1999-04-26 Application granted granted Critical

1999-04-26 Publication of DK0609310T3 publication Critical patent/DK0609310T3/da

Links

239000008194 pharmaceutical composition Substances 0.000 title abstract 2
150000001413 amino acids Chemical class 0.000 title 1
230000001225 therapeutic effect Effects 0.000 title 1
125000003118 aryl group Chemical group 0.000 abstract 4
150000001875 compounds Chemical class 0.000 abstract 3
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
125000002252 acyl group Chemical group 0.000 abstract 2
125000000217 alkyl group Chemical group 0.000 abstract 2
229910052799 carbon Inorganic materials 0.000 abstract 2
OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
125000003545 alkoxy group Chemical group 0.000 abstract 1
125000002947 alkylene group Chemical group 0.000 abstract 1
125000003435 aroyl group Chemical group 0.000 abstract 1
125000003710 aryl alkyl group Chemical group 0.000 abstract 1
150000001721 carbon Chemical group 0.000 abstract 1
125000001325 propanoyl group Chemical group O=C([*])C([H])([H])C([H])([H])[H] 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/60—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton with the carbon atom of at least one of the carboxyl groups bound to nitrogen atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C327/00—Thiocarboxylic acids
- C07C327/20—Esters of monothiocarboxylic acids
- C07C327/32—Esters of monothiocarboxylic acids having sulfur atoms of esterified thiocarboxyl groups bound to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/56—Ring systems containing bridged rings
- C07C2603/58—Ring systems containing bridged rings containing three rings
- C07C2603/70—Ring systems containing bridged rings containing three rings containing only six-membered rings
- C07C2603/74—Adamantanes

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Public Health (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

DK92921688T 1991-10-25 1992-10-21 N-(mercaptoacyl)aminosyrer, fremgangsmåder til fremstilling og terapeutisk anvendelse deraf og farmaceutiske sammensætninge DK0609310T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR9113174A FR2682952B1 (fr)	1991-10-25	1991-10-25	Nouveaux n-(mercaptoacyl) amino-acides, leur preparation et les compositions pharmaceutiques qui les contiennent.
PCT/EP1992/002412 WO1993008162A1 (en)	1991-10-25	1992-10-21	N-(mercaptoacyl)amino acids, methods of their preparation and therapeutic use, and pharmaceutical compositions containing them

Publications (1)

Publication Number	Publication Date
DK0609310T3 true DK0609310T3 (da)	1999-04-26

Family

ID=9418304

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK92921688T DK0609310T3 (da)	1991-10-25	1992-10-21	N-(mercaptoacyl)aminosyrer, fremgangsmåder til fremstilling og terapeutisk anvendelse deraf og farmaceutiske sammensætninge

Country Status (11)

Country	Link
EP (2)	EP0609310B1 (da)
JP (2)	JP3250806B2 (da)
AT (1)	ATE168995T1 (da)
AU (1)	AU666141B2 (da)
CA (1)	CA2121801A1 (da)
DE (1)	DE69226443T2 (da)
DK (1)	DK0609310T3 (da)
ES (1)	ES2118833T3 (da)
FR (1)	FR2682952B1 (da)
MX (1)	MX9206149A (da)
WO (1)	WO1993008162A1 (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT1273455B (it) *	1995-01-27	1997-07-08	Zambon Spa	Derivati tiolici ad attivita' inibitrice delle metallopeptidasi
FR2731219B1 (fr) *	1995-03-03	1997-04-25	Bioprojet Soc Civ	Procede de synthese d'acides acryliques alpha-substitues et leur application
IT1277736B1 (it) *	1995-12-28	1997-11-12	Zambon Spa	Derivati tiolici ad attivita' inibitrice delle metallopeptidasi
IT1277737B1 (it) *	1995-12-28	1997-11-12	Zambon Spa	Derivati tiolici ad attivita' inibitrice delle metallopeptidasi

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2480747A1 (fr)	1980-04-17	1981-10-23	Roques Bernard	Derives d'acides amines et leur application therapeutique
US4401677A (en)	1981-10-09	1983-08-30	E. R. Squibb & Sons, Inc.	Enkephalinase inhibitors
DE3467754D1 (de) *	1983-10-03	1988-01-07	Squibb & Sons Inc	Enkephalinase inhibitors
US4740499A (en)	1986-07-28	1988-04-26	Monsanto Company	Method of enhancing the bioactivity of atrial peptides
FR2617070A2 (fr) *	1987-03-23	1988-12-30	Collet Claude	Appareil de prehension, type mandrin, entierement automatique, a commandes d'ouverture et de fermeture ultra-rapides
CA1337400C (en) *	1987-06-08	1995-10-24	Norma G. Delaney	Inhibitors of neutral endopeptidase
US4879309A (en) *	1988-09-27	1989-11-07	Schering Corporation	Mercapto-acylamino acids as antihypertensives

1991
- 1991-10-25 FR FR9113174A patent/FR2682952B1/fr not_active Expired - Fee Related
1992
- 1992-10-21 EP EP92921688A patent/EP0609310B1/en not_active Expired - Lifetime
- 1992-10-21 AT AT92921688T patent/ATE168995T1/de not_active IP Right Cessation
- 1992-10-21 EP EP92117955A patent/EP0539848A1/en active Pending
- 1992-10-21 JP JP50744693A patent/JP3250806B2/ja not_active Expired - Fee Related
- 1992-10-21 AU AU27895/92A patent/AU666141B2/en not_active Ceased
- 1992-10-21 CA CA002121801A patent/CA2121801A1/en not_active Abandoned
- 1992-10-21 ES ES92921688T patent/ES2118833T3/es not_active Expired - Lifetime
- 1992-10-21 DK DK92921688T patent/DK0609310T3/da active
- 1992-10-21 DE DE69226443T patent/DE69226443T2/de not_active Expired - Fee Related
- 1992-10-21 WO PCT/EP1992/002412 patent/WO1993008162A1/en not_active Ceased
- 1992-10-23 MX MX9206149A patent/MX9206149A/es unknown
2001
- 2001-05-24 JP JP2001155490A patent/JP2002030066A/ja not_active Abandoned

Also Published As

Publication number	Publication date
EP0539848A1 (en)	1993-05-05
JPH07509441A (ja)	1995-10-19
FR2682952B1 (fr)	1993-12-03
JP3250806B2 (ja)	2002-01-28
WO1993008162A1 (en)	1993-04-29
DE69226443D1 (de)	1998-09-03
DE69226443T2 (de)	1999-02-04
JP2002030066A (ja)	2002-01-29
FR2682952A1 (fr)	1993-04-30
AU666141B2 (en)	1996-02-01
AU2789592A (en)	1993-05-21
MX9206149A (es)	1993-08-01
EP0609310B1 (en)	1998-07-29
EP0609310A1 (en)	1994-08-10
CA2121801A1 (en)	1993-04-29
ES2118833T3 (es)	1998-10-01
ATE168995T1 (de)	1998-08-15

Publication	Publication Date	Title
PH17740A (en)	1984-11-23	Substituted acyl derivatives of 1-2,3,4 tetrahydro-isoquinoline-3-carboxylic acids,their pharmaceutical compositions and use
ATE52498T1 (de)	1990-05-15	Amidderivate.
DE3372707D1 (en)	1987-09-03	Spiro-(4,(3+n))-2-aza-alkan-3-carboxylic-acid derivatives, process for their preparation,agents containing them and their use
DK0412404T3 (da)	1996-02-26	Thiazolderivater, fremgangsmåder til fremstilling deraf og farmaceutiske præparater omfattende derivaterne
ATE109770T1 (de)	1994-08-15	Derivate der coffeinsäure und pharmazeutische zusammensetzungen, die sie enthalten.
IL85768A (en)	1993-02-21	Benzoxazine derivatives, their preparation and pharmaceutical compositions containing them
GB8726763D0 (en)	1987-12-23	Thiazole compounds
DK0609310T3 (da)	1999-04-26	N-(mercaptoacyl)aminosyrer, fremgangsmåder til fremstilling og terapeutisk anvendelse deraf og farmaceutiske sammensætninge
DE68917211D1 (de)	1994-09-08	N-(5,6,7,8-Tetrahydropyrido(2,3-d)pyrimidin-6-yl-alkanoyl)-glutaminsäure-Derivate.
IL103595A0 (en)	1993-03-15	2-heterocyclicethylamine derivatives,their preparation and pharmaceutical compositions containing them
TW221429B (da)	1994-03-01
ATE123487T1 (de)	1995-06-15	Derivate der kaffeinsäure und sie enthaltende pharmazeutische zusammensetzungen.
EP0573659A4 (en)	1994-09-07	Pyrazolothiazolopyrimidine derivative
DE69011235D1 (de)	1994-09-08	Derivate von N-(Vincristinyl-23) und N-(Noranhydro-5-vinblastinyl-23) von Amino-1-methylphosphonsäure, ihre Verfahren zur Herstellung und sie enthaltende pharmazeutische Zusammensetzungen.