ATE169617T1 - Vitamin-d-amid-derivate - Google Patents
Vitamin-d-amid-derivateInfo
- Publication number
- ATE169617T1 ATE169617T1 AT94914472T AT94914472T ATE169617T1 AT E169617 T1 ATE169617 T1 AT E169617T1 AT 94914472 T AT94914472 T AT 94914472T AT 94914472 T AT94914472 T AT 94914472T AT E169617 T1 ATE169617 T1 AT E169617T1
- Authority
- AT
- Austria
- Prior art keywords
- group
- pct
- alpha
- vitamin
- sec
- Prior art date
Links
- 150000001408 amides Chemical class 0.000 title 1
- 229940088594 vitamin Drugs 0.000 title 1
- 229930003231 vitamin Natural products 0.000 title 1
- 235000013343 vitamin Nutrition 0.000 title 1
- 239000011782 vitamin Substances 0.000 title 1
- 150000003722 vitamin derivatives Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 229930003316 Vitamin D Natural products 0.000 abstract 1
- QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 abstract 1
- OFHCOWSQAMBJIW-AVJTYSNKSA-N alfacalcidol Chemical class C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C\C=C1\C[C@@H](O)C[C@H](O)C1=C OFHCOWSQAMBJIW-AVJTYSNKSA-N 0.000 abstract 1
- 125000001931 aliphatic group Chemical group 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 230000000125 calcaemic effect Effects 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- -1 cyclohexylidene moiety Chemical group 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000001747 exhibiting effect Effects 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 125000001570 methylene group Chemical group [H]C([H])([*:1])[*:2] 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 125000000962 organic group Chemical group 0.000 abstract 1
- 235000019166 vitamin D Nutrition 0.000 abstract 1
- 239000011710 vitamin D Substances 0.000 abstract 1
- 150000003710 vitamin D derivatives Chemical class 0.000 abstract 1
- 229940046008 vitamin d Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
- A61P5/12—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH for decreasing, blocking or antagonising the activity of the posterior pituitary hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
- C07D295/215—Radicals derived from nitrogen analogues of carbonic acid
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Oncology (AREA)
- Diabetes (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Communicable Diseases (AREA)
- Endocrinology (AREA)
- Pulmonology (AREA)
- Dermatology (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Saccharide Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB939309422A GB9309422D0 (en) | 1993-05-07 | 1993-05-07 | Chemical compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE169617T1 true ATE169617T1 (de) | 1998-08-15 |
Family
ID=10735089
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT94914472T ATE169617T1 (de) | 1993-05-07 | 1994-05-06 | Vitamin-d-amid-derivate |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US5756733A (de) |
| EP (1) | EP0696275B1 (de) |
| JP (1) | JP3703099B2 (de) |
| KR (1) | KR100321414B1 (de) |
| CN (1) | CN1093852C (de) |
| AT (1) | ATE169617T1 (de) |
| AU (1) | AU678246B2 (de) |
| CA (1) | CA2162272A1 (de) |
| CZ (1) | CZ291238B6 (de) |
| DE (1) | DE69412476T2 (de) |
| DK (1) | DK0696275T3 (de) |
| ES (1) | ES2122275T3 (de) |
| FI (1) | FI112361B (de) |
| GB (1) | GB9309422D0 (de) |
| HU (1) | HUT74165A (de) |
| IL (1) | IL109595A (de) |
| NO (1) | NO309187B1 (de) |
| NZ (1) | NZ265665A (de) |
| WO (1) | WO1994026707A1 (de) |
| ZA (1) | ZA943162B (de) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9405715D0 (en) * | 1994-03-23 | 1994-05-11 | Res Inst Medicine Chem | Chemical compounds |
| MX9709875A (es) * | 1995-06-06 | 1998-03-31 | Pfizer | N-(indol-2-carbonil)-glicinamidas substituidas y derivados como inhibidores de glicogeno fosforilasa, composiciones que las contienen y uso de las mismas. |
| DE19619036A1 (de) | 1996-04-30 | 1997-11-13 | Schering Ag | Neue Vitamin D-Derivate mit carbo- oder heterocyclischen Substituenten an C-25, Verfahren zu ihrer Herstellung und die Verwendung zur Herstellung von Arzneimitteln |
| GB9623569D0 (en) * | 1996-11-13 | 1997-01-08 | Immunodiagnostic Systems Ltd | Vitamin D immumoassay systems |
| US6043385A (en) * | 1997-12-16 | 2000-03-28 | Hoffman-La Roche Inc. | Vitamin D derivatives |
| GB9804861D0 (en) | 1998-03-06 | 1998-04-29 | Res Inst Medicine Chem | Chemical compounds |
| EP1123921A4 (de) * | 1998-10-23 | 2003-08-20 | Teijin Ltd | Vitamin d 3 derivate und diese enthaltende heilmittel für entzündliche erkrankungen der atemwege |
| EP1152749B1 (de) * | 1999-02-08 | 2006-04-12 | ALZA Corporation | Stabile nicht wässerige einphasige visköse vehikeln und formulierungen die diese vehikeln verwenden |
| DE19935771A1 (de) * | 1999-07-23 | 2001-02-01 | Schering Ag | Neue Vitamin D-Derivate mit cyclischen Substrukturen in den Seitenketten, Verfahren und Zwischenprodukte zu ihrer Herstellung und die Verwendung zur Herstellung von Arzneimitteln |
| US6703380B2 (en) | 1999-09-29 | 2004-03-09 | Colotech A/S | Prevention of cancer |
| DK1220676T3 (da) | 1999-09-29 | 2005-09-05 | Colotech As | Forebyggelse af colorektal cancer |
| US6989377B2 (en) | 1999-12-21 | 2006-01-24 | Wisconsin Alumni Research Foundation | Treating vitamin D responsive diseases |
| US6358939B1 (en) | 1999-12-21 | 2002-03-19 | Northern Lights Pharmaceuticals, Llc | Use of biologically active vitamin D compounds for the prevention and treatment of inflammatory bowel disease |
| ES2364623T3 (es) * | 2000-06-15 | 2011-09-08 | Chugai Seiyaku Kabushiki Kaisha | Derivados de vitamina d que poseen un átomo 22-oxa o 22-tia, una cadena lateral c17 sustituida con un grupo ácido, éster o amida y un enlace doble 16(17). |
| CN100469764C (zh) * | 2000-06-15 | 2009-03-18 | 中外制药株式会社 | 维生素d衍生物 |
| US6277877B1 (en) | 2000-08-15 | 2001-08-21 | Pfizer, Inc. | Substituted n-(indole-2-carbonyl)glycinamides and derivates as glycogen phosphorylase inhibitors |
| RU2323926C2 (ru) * | 2000-12-08 | 2008-05-10 | Чугаи Сейяку Кабусики Кайся | Способ карбонилирования |
| DE60324544D1 (de) * | 2002-04-26 | 2008-12-18 | Schering Corp | Muskarin antagonisten |
| KR20160112018A (ko) | 2006-06-02 | 2016-09-27 | 니뽄 신야쿠 가부시키가이샤 | 9,10-세코프레그난 유도체 및 의약 |
| WO2009117831A1 (en) * | 2008-03-27 | 2009-10-01 | The Royal Institution For The Advancement Of Learning/Mcgill University | Hybrid molecules having mixed vitamin d receptor agonism and histone deacetylase inhibitory properties |
| SG173119A1 (en) * | 2009-01-27 | 2011-08-29 | Berg Biosystems Llc | Vitamin d3 and analogs thereof for alleviating side effects associated with chemotherapy |
| MX366076B (es) | 2009-08-14 | 2019-06-27 | Berg Llc | Vitamina d3 y analogos de la misma para tratar alopecia. |
| WO2012151058A1 (en) | 2011-05-03 | 2012-11-08 | Wisconsin Alumni Research Foundation | (20s)-24-(p-toluenesulfonyloxy)-25,26,27-trinorvitamin d3 analogs and their uses |
| US8987235B2 (en) | 2011-05-17 | 2015-03-24 | Wisconsin Alumni Research Foundation | N-cyclopropyl-(20R)-2-methylene-19,26,27-trinor-25-aza-vitamin D analogs and their uses |
| SG10201709894RA (en) | 2013-05-29 | 2018-01-30 | Berg Llc | Preventing or mitigating chemotherapy induced alopecia using vitamin d |
| US9338493B2 (en) | 2014-06-30 | 2016-05-10 | Apple Inc. | Intelligent automated assistant for TV user interactions |
| US10548908B2 (en) | 2016-09-15 | 2020-02-04 | Nostopharma, LLC | Compositions and methods for preventing and treating heterotopic ossification and pathologic calcification |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8929059D0 (en) * | 1989-12-22 | 1990-02-28 | Leo Pharm Prod Ltd | Chemical compounds |
| PL171580B1 (pl) * | 1991-11-07 | 1997-05-30 | Res Inst Medicine Chem | Sposób wytwarzania nowych analogów witaminy D3 PL PL PL |
-
1993
- 1993-05-07 GB GB939309422A patent/GB9309422D0/en active Pending
-
1994
- 1994-05-06 US US08/532,799 patent/US5756733A/en not_active Expired - Fee Related
- 1994-05-06 CN CN94192435A patent/CN1093852C/zh not_active Expired - Fee Related
- 1994-05-06 CA CA002162272A patent/CA2162272A1/en not_active Abandoned
- 1994-05-06 KR KR1019950704980A patent/KR100321414B1/ko not_active Expired - Fee Related
- 1994-05-06 AT AT94914472T patent/ATE169617T1/de not_active IP Right Cessation
- 1994-05-06 HU HU9503190A patent/HUT74165A/hu unknown
- 1994-05-06 DK DK94914472T patent/DK0696275T3/da active
- 1994-05-06 NZ NZ265665A patent/NZ265665A/en unknown
- 1994-05-06 CZ CZ19952903A patent/CZ291238B6/cs not_active IP Right Cessation
- 1994-05-06 AU AU66832/94A patent/AU678246B2/en not_active Ceased
- 1994-05-06 WO PCT/GB1994/000975 patent/WO1994026707A1/en not_active Ceased
- 1994-05-06 EP EP94914472A patent/EP0696275B1/de not_active Expired - Lifetime
- 1994-05-06 DE DE69412476T patent/DE69412476T2/de not_active Expired - Fee Related
- 1994-05-06 ES ES94914472T patent/ES2122275T3/es not_active Expired - Lifetime
- 1994-05-06 ZA ZA943162A patent/ZA943162B/xx unknown
- 1994-05-06 JP JP52511994A patent/JP3703099B2/ja not_active Expired - Fee Related
- 1994-05-08 IL IL10959594A patent/IL109595A/xx not_active IP Right Cessation
-
1995
- 1995-11-06 FI FI955316A patent/FI112361B/fi not_active IP Right Cessation
- 1995-11-06 NO NO954426A patent/NO309187B1/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP3703099B2 (ja) | 2005-10-05 |
| FI112361B (fi) | 2003-11-28 |
| EP0696275A1 (de) | 1996-02-14 |
| WO1994026707A1 (en) | 1994-11-24 |
| FI955316A0 (fi) | 1995-11-06 |
| CA2162272A1 (en) | 1994-11-24 |
| NO954426D0 (no) | 1995-11-06 |
| AU678246B2 (en) | 1997-05-22 |
| KR100321414B1 (ko) | 2002-12-05 |
| ES2122275T3 (es) | 1998-12-16 |
| DE69412476D1 (de) | 1998-09-17 |
| AU6683294A (en) | 1994-12-12 |
| HU9503190D0 (en) | 1996-01-29 |
| IL109595A (en) | 1999-04-11 |
| CZ291238B6 (cs) | 2003-01-15 |
| CZ290395A3 (en) | 1996-06-12 |
| GB9309422D0 (en) | 1993-06-23 |
| FI955316A7 (fi) | 1995-12-22 |
| DK0696275T3 (da) | 1998-11-09 |
| CN1093852C (zh) | 2002-11-06 |
| HUT74165A (en) | 1996-11-28 |
| DE69412476T2 (de) | 1999-03-11 |
| ZA943162B (en) | 1995-04-13 |
| JPH08509971A (ja) | 1996-10-22 |
| NO309187B1 (no) | 2000-12-27 |
| NZ265665A (en) | 1997-05-26 |
| IL109595A0 (en) | 1994-08-26 |
| CN1125436A (zh) | 1996-06-26 |
| NO954426L (no) | 1996-01-08 |
| EP0696275B1 (de) | 1998-08-12 |
| US5756733A (en) | 1998-05-26 |
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| DE69414115D1 (de) | Vitamin d analoge | |
| FI942114A0 (fi) | D-vitamiiniamidijohdannaiset | |
| DE69425980D1 (de) | Vitamin d amin- und amidderivate | |
| NO963949D0 (no) | Amidderivater av vitamin D | |
| DE69122812D1 (de) | Glutathionderivat |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |