ATE169739T1 - Verfahren zum nachweis des abbaus von typ-i- kollagen - Google Patents

Verfahren zum nachweis des abbaus von typ-i- kollagen

Info

Publication number
ATE169739T1
ATE169739T1 AT92302446T AT92302446T ATE169739T1 AT E169739 T1 ATE169739 T1 AT E169739T1 AT 92302446 T AT92302446 T AT 92302446T AT 92302446 T AT92302446 T AT 92302446T AT E169739 T1 ATE169739 T1 AT E169739T1
Authority
AT
Austria
Prior art keywords
type
collagen
degradation
assay
sample
Prior art date
Application number
AT92302446T
Other languages
English (en)
Inventor
Juha Risteli
Leila Risteli
Original Assignee
Orion Yhtymae Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10691878&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE169739(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Orion Yhtymae Oy filed Critical Orion Yhtymae Oy
Application granted granted Critical
Publication of ATE169739T1 publication Critical patent/ATE169739T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6887—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids from muscle, cartilage or connective tissue
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/971—Capture of complex after antigen-antibody reaction
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/975—Kit
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/807—Apparatus included in process claim, e.g. physical support structures
    • Y10S436/808—Automated or kit

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
AT92302446T 1991-03-20 1992-03-20 Verfahren zum nachweis des abbaus von typ-i- kollagen ATE169739T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB919105893A GB9105893D0 (en) 1991-03-20 1991-03-20 Bone resorption assay based on a peptide liberated during collagen degradation

Publications (1)

Publication Number Publication Date
ATE169739T1 true ATE169739T1 (de) 1998-08-15

Family

ID=10691878

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92302446T ATE169739T1 (de) 1991-03-20 1992-03-20 Verfahren zum nachweis des abbaus von typ-i- kollagen

Country Status (9)

Country Link
US (1) US5538853A (de)
EP (1) EP0505210B2 (de)
JP (1) JP2886728B2 (de)
AT (1) ATE169739T1 (de)
DE (1) DE69226548T3 (de)
DK (1) DK0505210T4 (de)
ES (1) ES2120431T5 (de)
FI (1) FI103152B1 (de)
GB (1) GB9105893D0 (de)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5320970A (en) * 1987-11-06 1994-06-14 Washington Research Foundation Detection of collagen degradation in vivo
US6027903A (en) * 1987-11-06 2000-02-22 Washington Research Foundation Kit for detecting analyte indicative of type I collagen resorption in vivo
US6153732A (en) * 1987-11-06 2000-11-28 Washington Research Foundation Kit for detecting analyte indicative of type II collagen resorption in vivo
US5300434A (en) * 1987-11-06 1994-04-05 Washington Research Foundation Hybridoma cell line producing an antibody to type-I collagen amino-terminal telopeptide
US4973666A (en) * 1987-11-06 1990-11-27 Washington Research Foundation Peptide fragments containing HP and LP cross-links
US5962639A (en) * 1987-11-06 1999-10-05 Washington Research Foundation Synthetic peptides corresponding to telopeptide sequences of cross-linked type I collagen metabolites
DE4225038C2 (de) * 1992-07-29 1995-11-30 Boehringer Mannheim Gmbh Herstellung und Verwendung von Antikörpern gegen Kollagen
WO1994014070A1 (en) * 1992-12-04 1994-06-23 Shriners Hospitals For Crippled Children Immunoassay for the measurement of collagen cleavage in cartilage
US6132976A (en) * 1992-12-04 2000-10-17 Shriners Hospitals For Children Immunoassays for the measurement of collagen denaturation and cleavage in cartilage
EP0675903B1 (de) * 1992-12-28 2004-09-29 David J Baylink Methode zur messung der knochenresorption
EP0711415B1 (de) * 1993-07-28 1998-07-22 Boehringer Mannheim Gmbh Immunoassay zum nachweis von kollagen typ i oder kollagenfragmenten davon
DK104093D0 (da) * 1993-09-17 1993-09-17 Osteometer A S Fremgangsmaade til bestemmelse af collagen-fragmenter i legemsvaesker, test-kit og midler til udoevelse af fremgangsmaaden og anvendelse af fremgangsmaaden til diagnosticering af lidelser associeret til collagen-metabolismen
US6110689A (en) * 1994-01-21 2000-08-29 Osteometer A/S Method of assaying collagen fragments in body fluids, a test kit and means for carrying out the method and use of the method to diagnose the presence of disorders associated with the metabolism of collagen
WO1996012193A1 (en) * 1994-10-17 1996-04-25 Osteometer Bio Tech A/S Estimation of the fragmentation pattern of collagen in body fluids and the diagnosis of disorders associated with the metabolism of collagen
GB9506050D0 (en) * 1995-03-24 1995-05-10 Osteometer A S Assaying collagen fragments in body fluids
GB9507985D0 (en) * 1995-04-19 1995-06-07 Orion Yhtymae Oy Antibody to aminoterminal propeptide to type 1 procollagen and assay method using it
US6107047A (en) * 1996-03-21 2000-08-22 Osteometer Biotech A/S Assaying protein fragments in body fluids
GB9617616D0 (en) 1996-08-22 1996-10-02 Osteometer Biotech As Assaying protein fragments in body fluids
EP0829724A1 (de) * 1996-09-17 1998-03-18 Nederlandse Organisatie Voor Toegepast-Natuurwetenschappelijk Onderzoek Tno Verfahren zum Nachweis von Kollagenabbau
ES2160985T3 (es) 1996-12-09 2001-11-16 Osteometer Biotech As Ensayos de tipo sandwich para fragmentos de colageno.
DE69821246T2 (de) * 1997-07-31 2004-11-04 Metra Biosystems, Inc., Mountain View Testverfahren für collagenpeptid
US6117646A (en) * 1997-09-22 2000-09-12 Osteometer Biotech A/S Assaying protein fragments in body fluids
EP1088228B1 (de) 1998-06-19 2005-08-24 Washington Research Foundation Knorpelresorptionsassays
US6348320B1 (en) 1998-06-19 2002-02-19 Washington Research Foundation Cartilage resorption assays measuring type II collagen fragments
US6916903B2 (en) 1998-06-19 2005-07-12 Washington Research Foundation Collagen type III synthetic peptides for collagen resorption assays
US6602980B1 (en) 1998-06-19 2003-08-05 Washington Research Foundation Collagen type III synthetic peptides for collagen resorption assays
GB9907234D0 (en) * 1999-03-29 1999-05-26 Isis Innovation Drug assay
CA2525929A1 (en) 2003-05-13 2004-11-25 Chiron Corporation Methods of modulating metastasis and skeletal related events resulting from metastases
US7405037B2 (en) * 2004-05-07 2008-07-29 Lonza Walkersville, Inc. Methods and tools for detecting collagen degradation
WO2008037420A1 (en) * 2006-09-29 2008-04-03 Roche Diagnostics Gmbh Assessing the risk of disease progression for a patient with rheumatoid arthritis
TWI395593B (zh) 2008-03-06 2013-05-11 Halozyme Inc 可活化的基質降解酵素之活體內暫時性控制
WO2009153783A1 (en) * 2008-06-16 2009-12-23 Mor Research Applications Ltd. Monitoring skin metabolism products for evaluating burn injury
JP5649589B2 (ja) * 2009-03-06 2015-01-07 ハロザイム インコーポレイテッド マトリックスメタロプロテアーゼ１の温度感受性突然変異体およびその使用
WO2014107745A1 (en) 2013-01-07 2014-07-10 Halozyme, Inc. Metal sensitive mutants of matrix metalloproteases and uses thereof
CN106248970A (zh) * 2016-08-12 2016-12-21 江苏泽成生物技术有限公司 一种测定i型胶原c末端肽含量的试剂盒及其测试方法
JP7575824B1 (ja) * 2023-12-19 2024-10-30 株式会社DeVine 哺乳動物の歯に含まれるコラーゲンの所定の定量値を用いる方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1259914A (en) * 1984-07-06 1989-09-26 Donald G. Wallace Methods of bone repair using collagen
GB2205643B (en) * 1987-05-08 1991-03-13 Farmos Group Limited Type iii collagen degradation assay
US5300434A (en) * 1987-11-06 1994-04-05 Washington Research Foundation Hybridoma cell line producing an antibody to type-I collagen amino-terminal telopeptide
US4973666A (en) * 1987-11-06 1990-11-27 Washington Research Foundation Peptide fragments containing HP and LP cross-links
US4969912A (en) * 1988-02-18 1990-11-13 Kelman Charles D Human collagen processing and autoimplant use
GB8815174D0 (en) * 1988-06-25 1988-08-03 Rowett Research Inst Method of monitoring collagen degradation

Also Published As

Publication number Publication date
DE69226548T3 (de) 2005-10-06
DK0505210T4 (da) 2005-02-28
EP0505210A3 (en) 1993-06-16
JP2886728B2 (ja) 1999-04-26
DE69226548T2 (de) 1999-01-07
ES2120431T3 (es) 1998-11-01
FI921233A0 (fi) 1992-03-20
FI921233L (fi) 1992-09-21
DK0505210T3 (da) 1999-02-08
EP0505210B1 (de) 1998-08-12
US5538853A (en) 1996-07-23
FI103152B (fi) 1999-04-30
EP0505210A2 (de) 1992-09-23
EP0505210B2 (de) 2005-01-26
JPH0720126A (ja) 1995-01-24
GB9105893D0 (en) 1991-05-08
FI103152B1 (fi) 1999-04-30
ES2120431T5 (es) 2005-07-01
DE69226548D1 (de) 1998-09-17

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