ATE170923T1 - Nitratreduktase als marker für acremonium chrysogenum - Google Patents

Nitratreduktase als marker für acremonium chrysogenum

Info

Publication number
ATE170923T1
ATE170923T1 AT90904291T AT90904291T ATE170923T1 AT E170923 T1 ATE170923 T1 AT E170923T1 AT 90904291 T AT90904291 T AT 90904291T AT 90904291 T AT90904291 T AT 90904291T AT E170923 T1 ATE170923 T1 AT E170923T1
Authority
AT
Austria
Prior art keywords
cells
nitrate reductase
pct
marker
gene
Prior art date
Application number
AT90904291T
Other languages
English (en)
Inventor
John Anthony Birkett
James Robert Kinghorn
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Application granted granted Critical
Publication of ATE170923T1 publication Critical patent/ATE170923T1/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y107/00—Oxidoreductases acting on other nitrogenous compounds as donors (1.7)
    • C12Y107/99—Oxidoreductases acting on other nitrogenous compounds as donors (1.7) with other acceptors (1.7.99)
    • C12Y107/99004—Nitrate reductase (1.7.99.4)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C12N1/145—Fungi isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C12N9/0044—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on other nitrogen compounds as donors (1.7)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6897—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids involving reporter genes operably linked to promoters
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/645—Fungi ; Processes using fungi
    • C12R2001/80—Penicillium
    • C12R2001/82—Penicillium chrysogenum

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Mycology (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Botany (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
AT90904291T 1989-03-02 1990-03-02 Nitratreduktase als marker für acremonium chrysogenum ATE170923T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB898904762A GB8904762D0 (en) 1989-03-02 1989-03-02 Biological process

Publications (1)

Publication Number Publication Date
ATE170923T1 true ATE170923T1 (de) 1998-09-15

Family

ID=10652592

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90904291T ATE170923T1 (de) 1989-03-02 1990-03-02 Nitratreduktase als marker für acremonium chrysogenum

Country Status (9)

Country Link
US (1) US5302527A (de)
EP (1) EP0414870B1 (de)
JP (1) JP2983058B2 (de)
AT (1) ATE170923T1 (de)
DE (1) DE69032639T2 (de)
DK (1) DK0414870T3 (de)
ES (1) ES2119744T3 (de)
GB (1) GB8904762D0 (de)
WO (1) WO1990010074A1 (de)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH03254684A (ja) * 1990-03-02 1991-11-13 Asahi Chem Ind Co Ltd 新規ｃＤＮＡ化合物
WO1992007079A1 (en) * 1990-10-15 1992-04-30 Gist-Brocades N.V. Transformation selection marker system adapted for penicillium
EP0566897A3 (en) * 1992-04-07 1994-07-06 Hoechst Ag The complete gene (cefg) encoding the acetyl-coa: deacetylcephalosporin c acetyltransferase of cephalosporium acremonium, its isolation and use
DE69432543T2 (de) * 1993-07-23 2003-12-24 Dsm N.V., Te Heerlen Selektionmarker-genfreie rekombinante Stämme: Verfahren zur ihrer Herstellung und die Verwendung dieser Stämme
JP3619282B2 (ja) * 1994-04-01 2005-02-09 中外製薬株式会社 ＩｇＧＦｃ部結合タンパク質をコードする遺伝子
CN101659926A (zh) * 1994-06-30 2010-03-03 诺沃奇梅兹有限公司 非毒性、非产毒性、非致病性镰孢属表达系统及所用启动子和终止子
FR2723589B1 (fr) * 1994-08-12 1996-09-20 Bio Merieux Nouvel antigene de trypanosoma cruzi, et gene codant pour cette derniere; leur application a la detection de la maladie de chagas
US6001600A (en) * 1996-12-20 1999-12-14 Smithkline Beecham Plc DNA encoding tests polypeptides
US6010881A (en) * 1996-02-20 2000-01-04 Smithkline Beecham Corporation RibG
GB9607999D0 (en) * 1996-04-18 1996-06-19 Smithkline Beecham Plc Novel compounds
WO1998006734A1 (en) * 1996-08-16 1998-02-19 Smithkline Beecham Corporation Novel prokaryotic polynucleotides, polypeptides and their uses
EP0961547A4 (de) 1996-08-23 2002-08-14 Univ North Carolina State Neutralisationsempfindliche epitrope von cryptosporidiumparvum
JP4469026B2 (ja) * 1996-10-31 2010-05-26 ヒューマン ジノーム サイエンシーズ，インコーポレイテッド Ｓｔｒｅｐｔｏｃｏｃｃｕｓ ｐｎｅｕｍｏｎｉａｅの抗原およびワクチン
US6887663B1 (en) * 1996-10-31 2005-05-03 Human Genome Sciences, Inc. Streptococcus pneumoniae SP036 polynucleotides
US6383774B1 (en) * 1996-12-03 2002-05-07 Heska Corporation Parasitic nematode transglutaminase, nucleic acid molecules and uses thereof
AU6976098A (en) * 1997-04-15 1998-11-11 Eli Lilly And Company Ipc synthase genes from fungi
US5952196A (en) * 1997-04-18 1999-09-14 Smithkline Beecham Plc Prolyl tRNA synthetase polynucleotides
US5958733A (en) * 1997-04-18 1999-09-28 Smithkline Beecham Plc Threonyl tRNA synthetase polynucleotides
US6485904B1 (en) * 1997-06-23 2002-11-26 Pfizer, Inc. DNA encoding a plasminogen activating protein
US6800744B1 (en) * 1997-07-02 2004-10-05 Genome Therapeutics Corporation Nucleic acid and amino acid sequences relating to Streptococcus pneumoniae for diagnostics and therapeutics
US7115731B1 (en) 1997-07-02 2006-10-03 sanofi pasteur limited/ sanofi pasteur limiteé Nucleic acid and amino acid sequences relating to Streptococcus pneumoniae for diagnostics and therapeutics
WO1999035270A1 (en) * 1997-12-31 1999-07-15 Stressgen Biotechnologies Corporation Streptococcal heat shock proteins of the hsp60 family
US6306623B1 (en) * 1998-02-24 2001-10-23 The University Of California Leptospiral major outer membrane protein LipL32
US6521441B1 (en) * 1998-03-20 2003-02-18 Human Genome Sciences, Inc. Staphylococcus aureus genes and polypeptides
JP2002515253A (ja) * 1998-05-20 2002-05-28 ノボザイムス バイオテック，インコーポレイティド トリコテセン−欠失糸状菌変異体細胞において異種ポリベプチドを生成するための方法
JP2002521018A (ja) * 1998-07-23 2002-07-16 スミスクライン ビーチャム コーポレーション Ｓｃｒｐ−５：分泌型システインリッチタンパク質−５
US6649370B1 (en) * 1998-10-28 2003-11-18 Aventis Pasteur Limited Chlamydia antigens and corresponding DNA fragments and uses thereof
US7026156B1 (en) * 1999-02-04 2006-04-11 The University Of Georgia Research Foundation, Inc. Diagnostic and protective antigen gene sequences of ichthyophthirius
SE515819C2 (sv) * 1999-02-25 2001-10-15 Statens Veterinaermedicinska A Protein från kvalstret Sarcoptes scabiei
US6582950B1 (en) * 1999-10-04 2003-06-24 Regents Of The University Of Minnesota C3 binding polypeptide of Streptococcus agalactiae group b Streptococcus
GB0008748D0 (en) * 2000-04-11 2000-05-31 Univ Manchester Mutant bank
US20030199603A1 (en) * 2002-04-04 2003-10-23 3M Innovative Properties Company Cured compositions transparent to ultraviolet radiation
US7172868B2 (en) * 2002-08-01 2007-02-06 The Regents Of The University Of California Nucleotide sequences specific to Francisella tularensis and methods for the detection of Francisella tularensis
CA2532024A1 (en) * 2003-07-11 2005-01-20 Affinium Pharmaceuticals, Inc. Novel purified polypeptides from staphylococcus aureus
US7073678B1 (en) * 2003-08-04 2006-07-11 Helen Of Troy Limited Travel beverage container
US7550576B2 (en) * 2004-08-09 2009-06-23 North Carolina State University Nucleic acid sequences encoding two-component sensing and regulatory proteins, antimicrobial proteins and uses therefor
WO2007038578A1 (en) * 2005-09-27 2007-04-05 The Gov't. Of The Usa As Represented By The Sec. Of The Dept. Of Health & Human Services, Center For Disease Control And Prevention Compositions and methods for the detection of candida species

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8508800D0 (en) * 1985-04-04 1985-05-09 Glaxo Group Ltd Microbiological process
PT83621B (en) * 1985-10-28 1988-03-02 Gen Hospital Corp Method for producing polynucleotides coding for nitrate reductase
DK173292B1 (da) * 1986-01-31 2000-06-13 Antibioticos Sa Fremgangsmåde til selekterbar transformation af Pencillium chrysogenum, plasmider til anvendelse ved fremgangsmåden samt P.
DE3789880T2 (de) * 1986-01-31 1994-09-08 Beecham Group Plc Isolierung und Expression von bei der Biosynthese von Beta-Laktamen beteiligten Genen.

Also Published As

Publication number Publication date
DE69032639D1 (en) 1998-10-15
GB8904762D0 (en) 1989-04-12
EP0414870A1 (de) 1991-03-06
JP2983058B2 (ja) 1999-11-29
DK0414870T3 (da) 1999-06-07
ES2119744T3 (es) 1998-10-16
WO1990010074A1 (en) 1990-09-07
EP0414870B1 (de) 1998-09-09
DE69032639T2 (de) 1999-01-28
US5302527A (en) 1994-04-12
JPH03504334A (ja) 1991-09-26

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Legal Events

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UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee