ATE170979T1 - Herstellung und stabilisierung von zellsuspensionen - Google Patents

Herstellung und stabilisierung von zellsuspensionen

Info

Publication number
ATE170979T1
ATE170979T1 AT95916610T AT95916610T ATE170979T1 AT E170979 T1 ATE170979 T1 AT E170979T1 AT 95916610 T AT95916610 T AT 95916610T AT 95916610 T AT95916610 T AT 95916610T AT E170979 T1 ATE170979 T1 AT E170979T1
Authority
AT
Austria
Prior art keywords
pct
cell suspension
solution
heavy metal
stabilization
Prior art date
Application number
AT95916610T
Other languages
English (en)
Inventor
Vivian Granger
David Barnett
Original Assignee
North Gen Hospital Nhs Trust
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB9406698A external-priority patent/GB9406698D0/en
Priority claimed from GB9413558A external-priority patent/GB2279653B/en
Application filed by North Gen Hospital Nhs Trust filed Critical North Gen Hospital Nhs Trust
Application granted granted Critical
Publication of ATE170979T1 publication Critical patent/ATE170979T1/de

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5094Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for blood cell populations
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5002Partitioning blood components
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966Animal cells
    • G01N33/56972White blood cells
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966Animal cells
    • G01N33/56977HLA or MHC typing
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/96Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood or serum control standard
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2496/00Reference solutions for assays of biological material
    • G01N2496/05Reference solutions for assays of biological material containing blood cells or plasma
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/10Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/101666Particle count or volume standard or control [e.g., platelet count standards, etc.]
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/10Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/107497Preparation composition [e.g., lysing or precipitation, etc.]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Zoology (AREA)
  • Virology (AREA)
  • Ecology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Processing Of Solid Wastes (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
AT95916610T 1994-04-05 1995-04-05 Herstellung und stabilisierung von zellsuspensionen ATE170979T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9406698A GB9406698D0 (en) 1994-04-05 1994-04-05 Preparation and stabilisation of cell suspensions
GB9413558A GB2279653B (en) 1993-07-05 1994-07-05 Stabilisation of cells with an agent comprising a heavy metal compound

Publications (1)

Publication Number Publication Date
ATE170979T1 true ATE170979T1 (de) 1998-09-15

Family

ID=26304635

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95916610T ATE170979T1 (de) 1994-04-05 1995-04-05 Herstellung und stabilisierung von zellsuspensionen

Country Status (16)

Country Link
US (1) US5858699A (de)
EP (1) EP0754301B1 (de)
JP (1) JPH10503008A (de)
CN (1) CN1149338A (de)
AT (1) ATE170979T1 (de)
AU (1) AU695573B2 (de)
BR (1) BR9507288A (de)
CA (1) CA2187196A1 (de)
DE (1) DE69504646T2 (de)
DK (1) DK0754301T3 (de)
ES (1) ES2122589T3 (de)
FI (1) FI963978A7 (de)
NO (1) NO964225L (de)
NZ (1) NZ284451A (de)
PL (1) PL176318B1 (de)
WO (1) WO1995027203A1 (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2197168T3 (es) 1993-07-05 2004-01-01 Sheffield Teaching Hospitals National Health Service Trust Preparacion y estabilizacion de celulas.
CN1149338A (zh) * 1994-04-05 1997-05-07 北方总医院N·H·S·托拉斯 细胞悬浮液的制备和稳定化
GB2313288B (en) * 1996-05-24 2000-07-12 North Gen Hospital Nhs Trust Specimen collection fluid
CA2445204C (en) * 2002-10-16 2014-08-12 Streck Laboratories, Inc. Method and device for collecting and preserving cells for analysis
CN102879317B (zh) * 2003-06-18 2016-04-13 稳定技术公司 分散相和乳化液的加速稳定性评估
US20050085028A1 (en) * 2003-10-21 2005-04-21 International Business Machines Corporation Method and structure to suppress external latch-up
CN100376669C (zh) 2005-02-25 2008-03-26 深圳迈瑞生物医疗电子股份有限公司 生物红细胞体积长期稳定的处理方法
WO2010078194A1 (en) 2008-12-30 2010-07-08 Streck, Inc. Method for screening blood using a preservative that may be in a substantially solid state form
US11634747B2 (en) * 2009-01-21 2023-04-25 Streck Llc Preservation of fetal nucleic acids in maternal plasma
NO2398912T3 (de) 2009-02-18 2018-02-10
US20110111410A1 (en) * 2009-11-09 2011-05-12 Streck, Inc. Stabilization of rna in intact cells within a blood sample
US20110224495A1 (en) * 2010-03-12 2011-09-15 Tyco Healthcare Group Lp Surgical access port
EP2618658A2 (de) 2010-09-21 2013-07-31 Herz- und Diabeteszentrum Nordrhein-Westfalen Krankenhausbetriebsgesellschaft Bad Oeynhausen mbH Stabilisierte leukozyten und ihre verwendung für die diagnose und therapie von hiv
US9956281B2 (en) 2011-05-04 2018-05-01 Streck, Inc. Inactivated virus compositions and methods of preparing such compositions
FR3005420B1 (fr) 2013-05-07 2015-09-18 Erytech Pharma Procede de stabilisation de suspensions d'erythrocytes encapsulant un principe actif, suspensions obtenues.
US10091984B2 (en) 2013-07-24 2018-10-09 Streck, Inc. Compositions and methods for stabilizing circulating tumor cells
US11168351B2 (en) 2015-03-05 2021-11-09 Streck, Inc. Stabilization of nucleic acids in urine
US20170145475A1 (en) 2015-11-20 2017-05-25 Streck, Inc. Single spin process for blood plasma separation and plasma composition including preservative
WO2018022991A1 (en) 2016-07-29 2018-02-01 Streck, Inc. Suspension composition for hematology analysis control
WO2018136751A1 (en) 2017-01-22 2018-07-26 Chryos, Llc Composition and method of use of the same for preserving cells for analysis
CN115119829B (zh) 2017-10-19 2024-07-12 斯特雷克股份有限公司 用于胞外囊泡的溶血和凝血调节以及稳定化的组合物

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1068862B (de) * 1957-05-03 1959-11-12 Penicillin-Gesellschaft Dauelsberg a Co., Göttingen Verfahren zur Verlängerung der Haltbarkeit von Blutkonserven
DE1147004B (de) * 1959-10-16 1963-04-11 Dr Med Herbert Fischer Verfahren zur Konservierung von lebenden menschlichen oder tierischen Zellpraeparaten, insbesondere von Blut und Blutbestandteilen
CA933092A (en) * 1969-04-10 1973-09-04 V. Collins Zeola Method of prolonging the viability of lymphocytes
FR2202688B1 (de) * 1972-10-17 1977-04-15 Cepbepe
US4045488A (en) * 1974-11-06 1977-08-30 Pfizer Inc. Aminophenyltetralin compounds
IT1065125B (it) * 1975-08-20 1985-02-25 Boehringer Mannheim Gmbh Processo per mantenere costante l attivita di fosfatasi alcalina e siero di controllo contenente tale fosfatasi
DE2551208C3 (de) * 1975-11-14 1981-05-27 Behringwerke Ag, 3550 Marburg Verfahren zur Herstellung einer stabilen Erythrozyten-Präparation
US4040785A (en) * 1976-10-18 1977-08-09 Technicon Instruments Corporation Lysable blood preservative composition
US4152208A (en) * 1977-03-29 1979-05-01 Hoffmann-La Roche Inc. Stabilized leucocytes
DE2828820A1 (de) * 1977-08-01 1979-02-08 Warner Lambert Co Verfahren zur herstellung einer stabilen blutplaettchensuspension und nach dem verfahren erhaltene stabile blutplaettchensuspension
US4324687A (en) * 1979-02-15 1982-04-13 Louderback Allan Lee Blood biochemistry control standard
DE2949824A1 (de) * 1979-12-12 1981-07-02 Marianne Dr. 5000 Köln Sehrbundt Verfahren zur stabilisierung von lymphozyten/thrombozytennmischsuspensionen
US4346018A (en) * 1980-06-16 1982-08-24 Coulter Electronics, Inc. Multi-purpose blood diluent and lysing agent for differential determination of lymphoid-myeloid population of leukocytes
US4405719A (en) * 1981-05-29 1983-09-20 Coulter Electronics, Inc. Method of stabilizing platelets for determining multiple platelet parameters in reference control and calibrator compositions; diluents therefor; and combination stabilization procedures
US4704352A (en) * 1985-06-25 1987-11-03 Baxter Travenol Laboratories, Inc. L-ascorbate-2-phosphate salts in blood cell storage
US4833090A (en) * 1985-08-08 1989-05-23 Eberhard Liss Preservation of glucose in blood
US4675185A (en) * 1985-12-06 1987-06-23 Baxter Travenol Laboratories, Inc. Solution for stabilizing red blood cells during storage
US4729959A (en) * 1986-02-24 1988-03-08 Streck Laboratories, Inc. Glucose reference control for glucose test strips
US4806343A (en) * 1986-03-13 1989-02-21 University Of Southwestern Louisiana Cryogenic protectant for proteins
US5250438A (en) * 1990-05-09 1993-10-05 Streck Laboratories, Inc. Method for differential determination of white blood cells using diazolidinyl urea to stabilize white blood cells
SU1767436A1 (ru) * 1990-05-22 1992-10-07 Черновицкий Государственный Университет Способ определени глюкозы в крови
US5260048A (en) * 1991-05-08 1993-11-09 Streck Laboratories, Inc. Tissue fixative solution and method
US5270208A (en) * 1991-05-09 1993-12-14 Streck Laboratories, Inc. White blood cell hematology control
JPH0820452B2 (ja) * 1991-12-16 1996-03-04 株式会社いかがく 血液中糖類の微生物による消費阻止方法
US5422277A (en) * 1992-03-27 1995-06-06 Ortho Diagnostic Systems Inc. Cell fixative composition and method of staining cells without destroying the cell surface
WO1993021928A1 (en) * 1992-04-24 1993-11-11 Streck Laboratories, Inc. Liquid glucose control solution and process of making the same
EP0639985B1 (de) * 1992-09-10 2004-08-11 Streck Laboratories, Inc. Verfahren und zusammensetzung zur konservierung von antigenen und verfahren zur verwendung von durch selbiges verfahren hergestellten zytologischem material
ES2197168T3 (es) * 1993-07-05 2004-01-01 Sheffield Teaching Hospitals National Health Service Trust Preparacion y estabilizacion de celulas.
CN1149338A (zh) * 1994-04-05 1997-05-07 北方总医院N·H·S·托拉斯 细胞悬浮液的制备和稳定化

Also Published As

Publication number Publication date
PL176318B1 (pl) 1999-05-31
EP0754301B1 (de) 1998-09-09
FI963978L (fi) 1996-12-02
US5858699A (en) 1999-01-12
BR9507288A (pt) 1997-09-23
WO1995027203A1 (en) 1995-10-12
NO964225L (no) 1996-12-05
FI963978A7 (fi) 1996-12-02
DK0754301T3 (da) 1999-06-07
DE69504646D1 (de) 1998-10-15
NO964225D0 (no) 1996-10-04
CA2187196A1 (en) 1995-10-12
FI963978A0 (fi) 1996-10-04
CN1149338A (zh) 1997-05-07
AU695573B2 (en) 1998-08-13
PL316657A1 (en) 1997-02-03
ES2122589T3 (es) 1998-12-16
AU2305195A (en) 1995-10-23
NZ284451A (en) 1998-03-25
EP0754301A1 (de) 1997-01-22
DE69504646T2 (de) 1999-04-29
JPH10503008A (ja) 1998-03-17

Similar Documents

Publication Publication Date Title
ATE170979T1 (de) Herstellung und stabilisierung von zellsuspensionen
PL307245A1 (en) Catalysts and their application in oxidation of saturated hydrocarbons
DE69428791D1 (de) Verwendung vonModafinil zur Behandlung von Atemstillstand im Schlaf und zentral erregten Atembeschwerden
EP0176032A3 (en) Tetralin derivatives, their preparation and use
ATE298741T1 (de) Polyaromatische verbindungen zur behandlung von herpes-infektionen
BR9407910A (pt) Composto composiçao farmacêutica uso do composto processo de tratamento de distúrbios no sistema nervoso central e processo de preparaçao do composto
NO970164D0 (no) Anvendelse av tiazol- og tiadiazolforbindelser som D3 - dopaminreseptorligander
DK0782567T3 (da) Isothiourinstofderivater og fremgangsmåder til deres fremstilling
PT1149910E (pt) Composicao farmaceutica contra os tumores e as infeccoes por papilomavirus
AU587995B2 (en) 1-substituted tetralin derivatives, their preparation and their use
FR2742048B1 (fr) Utilisation de l'alpha-cyano-beta, beta-diphenylacrylate de 2-ethylhexyle pour ameliorer la stabilite de compositions cosmetiques contenant le p-methyl-benzylidene camphre en association avec un derive de dibenzoylmethane
SG82540A1 (en) N-substituted azabicyclo [3.2.0] heptane derivatives as neuroleptics, the preparation and use thereof
ATE87907T1 (de) Basisch substituierte phenylacetonitrile, ihre herstellung und diese enthaltende arzneimittel.
DE3463385D1 (en) Compounds for treating hypertension
HUT71512A (en) N-(3-chlorophenyl)-piperazine derivatives for producing alkyl-trazodon derivatives and process for producing them
GB9607034D0 (en) Chemical compounds
CZ157795A3 (en) Pharmaceutical preparations for treating prostatitis
ATE267018T1 (de) Verwendung von peptidverbindungen zur behandlung von sle
IL138638A0 (en) Processes for preparing intermediates
BR9507623A (pt) Composto processo e precursor para á preparação do mesmo
DK0713485T3 (da) Thiocarbamoylforbindelser som mikrobicider
ES8501397A1 (es) "procedimiento para preparar derivados de quinazolina"
ES8101558A1 (es) Un procedimiento para la preparacion de n-aril-n'-(2-imida- zolidinilioden)ureas
MX9703846A (es) Nuevos derivados de 10, 11-dihidro-10-oxo-5h-dibenz/b, f/azepina-5-carboxamida.
UA10153A (uk) beta-[beta'-(2,4-ДІ-ТРЕТ-АМІЛФЕНОКСИ)-ЕТОКСИ] ЕТИЛХЛОРИД ЯК НАПІВПРОДУКТ ДЛЯ ОДЕРЖАННЯ РЕЧОВИН, ЯКІ МАЮТЬ АНТИМІКРОБНІ ВЛАСТИВОСТІ

Legal Events

Date Code Title Description
EEIH Change in the person of patent owner
REN Ceased due to non-payment of the annual fee