ATE173618T1 - Transdermales matrixsystem auf basis eines styrol-isopren-styrol copolymers zur verabreichung eines östrogens und/oder gestagens - Google Patents

Transdermales matrixsystem auf basis eines styrol-isopren-styrol copolymers zur verabreichung eines östrogens und/oder gestagens

Info

Publication number
ATE173618T1
ATE173618T1 AT95400574T AT95400574T ATE173618T1 AT E173618 T1 ATE173618 T1 AT E173618T1 AT 95400574 T AT95400574 T AT 95400574T AT 95400574 T AT95400574 T AT 95400574T AT E173618 T1 ATE173618 T1 AT E173618T1
Authority
AT
Austria
Prior art keywords
styrene
pts
isoprene
progestagen
estrogen
Prior art date
Application number
AT95400574T
Other languages
English (en)
Inventor
Claude Mikler
Laurent Liorzou
Daniel Dhuique-Mayer
Original Assignee
Lhd Lab Hygiene Dietetique
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lhd Lab Hygiene Dietetique filed Critical Lhd Lab Hygiene Dietetique
Application granted granted Critical
Publication of ATE173618T1 publication Critical patent/ATE173618T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7076—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising ingredients of undetermined constitution or reaction products thereof, e.g. rosin or other plant resins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Dermatology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Botany (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Adhesives Or Adhesive Processes (AREA)
AT95400574T 1994-03-28 1995-03-15 Transdermales matrixsystem auf basis eines styrol-isopren-styrol copolymers zur verabreichung eines östrogens und/oder gestagens ATE173618T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9403599A FR2717689B1 (fr) 1994-03-28 1994-03-28 Système matriciel transdermique d'administration d'un oestrogène et/ou un progestatif à base de copolymère styrène-isoprène-styrène.

Publications (1)

Publication Number Publication Date
ATE173618T1 true ATE173618T1 (de) 1998-12-15

Family

ID=9461479

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95400574T ATE173618T1 (de) 1994-03-28 1995-03-15 Transdermales matrixsystem auf basis eines styrol-isopren-styrol copolymers zur verabreichung eines östrogens und/oder gestagens

Country Status (23)

Country Link
US (1) US5580572A (de)
EP (1) EP0674901B1 (de)
JP (1) JPH07330609A (de)
KR (1) KR950031057A (de)
CN (1) CN1114903A (de)
AT (1) ATE173618T1 (de)
AU (1) AU691558B2 (de)
CA (1) CA2145584A1 (de)
CZ (1) CZ76795A3 (de)
DE (1) DE69506157T2 (de)
DK (1) DK0674901T3 (de)
ES (1) ES2128673T3 (de)
FI (1) FI951424A7 (de)
FR (1) FR2717689B1 (de)
GR (1) GR3029401T3 (de)
HU (1) HU219465B (de)
LV (1) LV10929B (de)
NO (1) NO951126L (de)
NZ (1) NZ270811A (de)
PL (1) PL178896B1 (de)
RU (1) RU2110282C1 (de)
SK (1) SK39095A3 (de)
ZA (1) ZA952469B (de)

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JP3238389B2 (ja) * 1988-10-27 2001-12-10 シエーリング アクチエンゲゼルシヤフト ゲストデン含有の経皮適用のための薬剤
US6148830A (en) 1994-04-19 2000-11-21 Applied Elastomerics, Inc. Tear resistant, multiblock copolymer gels and articles
US7208184B2 (en) 2002-07-20 2007-04-24 Applied Elastomerics, Inc. Gelatinous food elastomer compositions and articles for use as fishing bait
US7134236B2 (en) * 1994-04-19 2006-11-14 Applied Elastomerics, Inc. Gelatinous elastomer compositions and articles for use as fishing bait
US7108873B2 (en) 1994-04-19 2006-09-19 Applied Elastomerics, Inc. Gelatinous food elastomer compositions and articles
US7226484B2 (en) 1994-04-19 2007-06-05 Applied Elastomerics, Inc. Tear resistant gels and articles for every uses
US7290367B2 (en) 1994-04-19 2007-11-06 Applied Elastomerics, Inc. Tear resistant gel articles for various uses
US7234560B2 (en) * 1994-04-19 2007-06-26 Applied Elastomerics, Inc. Inflatable restraint cushions and other uses
EP0787488A4 (de) * 1994-11-18 1998-06-03 Hisamitsu Pharmaceutical Co Transdermal absorbierbares pflaster
FR2739031B1 (fr) * 1995-09-27 1997-11-21 Lhd Lab Hygiene Dietetique Systeme matriciel transdermique d'administration d'un oestrogene et/ou d'un progestatif a base de copolymere styrene-isoprene-styrene, procede de preparation et utilisation en therapeutique
JP3857348B2 (ja) * 1996-02-20 2006-12-13 ソニー株式会社 テープカートリッジ
DE19700913C2 (de) * 1997-01-14 2001-01-04 Lohmann Therapie Syst Lts Transdermales therapeutisches System zur Abgabe von Hormonen
DE19918106A1 (de) * 1999-04-22 2000-10-26 Lohmann Therapie Syst Lts Transdermales therapeutisches System mit neutralisierten Acrylathaftklebern
WO2001001990A1 (en) * 1999-07-01 2001-01-11 Hisamitsu Pharmaceutical Co., Inc. Adhesive preparation for percutaneous absorption
JP4648518B2 (ja) * 2000-06-01 2011-03-09 帝國製薬株式会社 ４−ビフェニル酢酸含有貼付剤
DE10236319A1 (de) * 2002-08-08 2004-02-19 Beiersdorf Ag Hautfreundliche Wirkstoffpflaster auf der Basis von SBC mit mindestens einem pharmazeutischen Wirkstoff mit einem Gehalt von mindestens 34 Gew.-% und dessen Herstellung
US20050191339A1 (en) * 2002-08-08 2005-09-01 Beiersdorf Ag Skin friendly active ingredient plaster based on SBC, containing at least 34 WT.% of a pharmaceutical active ingredient and production thereof
JP2004224741A (ja) * 2003-01-23 2004-08-12 Hisamitsu Pharmaceut Co Inc ツロブテロール経皮吸収型製剤
JP4422430B2 (ja) * 2003-05-14 2010-02-24 帝國製薬株式会社 エストロゲン及び／又はプロゲストゲン含有外用貼付剤
JP4311728B2 (ja) * 2003-12-10 2009-08-12 ニチバン株式会社 経皮吸収型貼付剤
DE102004028284A1 (de) * 2004-06-11 2006-01-05 Hexal Ag Matrixkontrolliertes transdermales therapeutisches System auf Basis eines Schmelzklebstoffs zur Anwendung von Norelgestromin
US20070062884A1 (en) 2005-08-11 2007-03-22 Board Of Regents, The University Of Texas System N-halamines compounds as multifunctional additives
WO2007129427A1 (ja) * 2006-05-08 2007-11-15 Teikoku Seiyaku Co., Ltd. 抗認知症薬物の経皮吸収製剤
RS62297B1 (sr) 2011-11-23 2021-09-30 Therapeuticsmd Inc Prirodne kombinovane hormonske supstitucione formulacije i terapije
US9301920B2 (en) 2012-06-18 2016-04-05 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US10806740B2 (en) 2012-06-18 2020-10-20 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US10806697B2 (en) 2012-12-21 2020-10-20 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US20150196640A1 (en) 2012-06-18 2015-07-16 Therapeuticsmd, Inc. Progesterone formulations having a desirable pk profile
US20130338122A1 (en) 2012-06-18 2013-12-19 Therapeuticsmd, Inc. Transdermal hormone replacement therapies
US11266661B2 (en) 2012-12-21 2022-03-08 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10471072B2 (en) 2012-12-21 2019-11-12 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10568891B2 (en) 2012-12-21 2020-02-25 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10537581B2 (en) 2012-12-21 2020-01-21 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11246875B2 (en) 2012-12-21 2022-02-15 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US9180091B2 (en) 2012-12-21 2015-11-10 Therapeuticsmd, Inc. Soluble estradiol capsule for vaginal insertion
RU2016143081A (ru) 2014-05-22 2018-06-26 Терапьютиксмд, Инк. Натуральные комбинированные гормонозаместительные составы и терапии
US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
US9931349B2 (en) 2016-04-01 2018-04-03 Therapeuticsmd, Inc. Steroid hormone pharmaceutical composition
US10286077B2 (en) 2016-04-01 2019-05-14 Therapeuticsmd, Inc. Steroid hormone compositions in medium chain oils
US11633405B2 (en) 2020-02-07 2023-04-25 Therapeuticsmd, Inc. Steroid hormone pharmaceutical formulations

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Publication number Priority date Publication date Assignee Title
US4299501A (en) * 1979-08-10 1981-11-10 Ortho Pharmaceutical Corporation Continuous process for the preparation of semisolid dispersions
JPS60188315A (ja) * 1984-03-07 1985-09-25 Yamanouchi Pharmaceut Co Ltd グリチルレチン酸配合鎮痒プラスター
US4994267A (en) * 1988-03-04 1991-02-19 Noven Pharmaceuticals, Inc. Transdermal acrylic multipolymer drug delivery system
US5032402A (en) * 1988-10-27 1991-07-16 The University Of Kentucky Research Foundation 3-hydroxy-N-methylpyrrolidone and use as transdermal enhancer
DE69108512T2 (de) * 1990-05-17 1995-08-03 Hisamitsu Pharmaceutical Co Estradiol enthaltende transdermale zubereitung.
US5232702A (en) * 1991-07-22 1993-08-03 Dow Corning Corporation Silicone pressure sensitive adhesive compositons for transdermal drug delivery devices and related medical devices
JPH05331064A (ja) * 1992-05-26 1993-12-14 Sekisui Chem Co Ltd 消炎鎮痛貼付剤

Also Published As

Publication number Publication date
FI951424A0 (fi) 1995-03-24
AU691558B2 (en) 1998-05-21
FR2717689B1 (fr) 1996-07-05
CN1114903A (zh) 1996-01-17
RU2110282C1 (ru) 1998-05-10
JPH07330609A (ja) 1995-12-19
LV10929B (en) 1996-08-20
CA2145584A1 (en) 1995-09-29
HU219465B (hu) 2001-04-28
EP0674901A1 (de) 1995-10-04
NO951126D0 (no) 1995-03-24
DK0674901T3 (da) 1999-08-09
ZA952469B (en) 1995-12-19
PL307891A1 (en) 1995-10-02
KR950031057A (ko) 1995-12-18
DE69506157T2 (de) 1999-07-01
PL178896B1 (pl) 2000-06-30
EP0674901B1 (de) 1998-11-25
AU1497895A (en) 1995-10-05
HU9500880D0 (en) 1995-05-29
US5580572A (en) 1996-12-03
CZ76795A3 (en) 1995-10-18
ES2128673T3 (es) 1999-05-16
SK39095A3 (en) 1995-10-11
LV10929A (lv) 1995-12-20
NO951126L (no) 1995-09-29
DE69506157D1 (de) 1999-01-07
GR3029401T3 (en) 1999-05-28
FR2717689A1 (fr) 1995-09-29
HUT75238A (en) 1997-05-28
FI951424A7 (fi) 1995-09-29
NZ270811A (en) 1995-12-21

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Legal Events

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UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee