ATE174122T1 - Blutplättchen blockade test - Google Patents

Blutplättchen blockade test

Info

Publication number
ATE174122T1
ATE174122T1 AT95935026T AT95935026T ATE174122T1 AT E174122 T1 ATE174122 T1 AT E174122T1 AT 95935026 T AT95935026 T AT 95935026T AT 95935026 T AT95935026 T AT 95935026T AT E174122 T1 ATE174122 T1 AT E174122T1
Authority
AT
Austria
Prior art keywords
iiia
glycoprotein iib
results
blockade
assay
Prior art date
Application number
AT95935026T
Other languages
English (en)
Inventor
Barry S Coller
Original Assignee
Sinai School Medicine
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sinai School Medicine filed Critical Sinai School Medicine
Application granted granted Critical
Publication of ATE174122T1 publication Critical patent/ATE174122T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5091—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/975—Kit

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Physiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AT95935026T 1994-09-29 1995-09-20 Blutplättchen blockade test ATE174122T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/315,026 US5763199A (en) 1994-09-29 1994-09-29 Platelet blockade assay

Publications (1)

Publication Number Publication Date
ATE174122T1 true ATE174122T1 (de) 1998-12-15

Family

ID=23222552

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95935026T ATE174122T1 (de) 1994-09-29 1995-09-20 Blutplättchen blockade test

Country Status (12)

Country Link
US (2) US5763199A (de)
EP (1) EP0783696B1 (de)
JP (1) JPH10506988A (de)
AT (1) ATE174122T1 (de)
AU (1) AU3720095A (de)
CA (1) CA2201283C (de)
DE (1) DE69506434T2 (de)
DK (1) DK0783696T3 (de)
ES (1) ES2127563T3 (de)
GR (1) GR3029470T3 (de)
IL (1) IL115431A (de)
WO (1) WO1996010749A1 (de)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19620443C2 (de) * 1996-05-21 1998-09-17 Rhein Biotech Proz & Prod Gmbh Verfahren zum automatischen Durchführen von Bluttests
US5922551A (en) * 1997-03-20 1999-07-13 Accumetrics, Inc. Agglutrimetric platelet binding assays in blood
EP0983509B1 (de) * 1997-05-14 2005-08-17 Biosite Diagnostics Inc. Schnelle bestimmung des verhältnisses von biologischen molekülen
FR2764388B1 (fr) * 1997-06-06 1999-08-27 Biocytex Nouvelle methode d'analyse des recepteurs plaquettaires gpiib/iiia
DE19836559A1 (de) * 1998-08-12 2000-03-23 Antigen Gmbh Gefäß zur Entnahme von Blut
AU1218900A (en) * 1998-10-23 2000-05-15 Accumetrics, Inc. Method for determining platelet count
DE69941031D1 (de) * 1998-11-12 2009-08-06 Novolytics Inc Zusammensetzungen und verfahren zur erzeugung von gefässeokklusion
WO2000073792A1 (en) * 1999-05-28 2000-12-07 Sendx Medical, Inc. Control for methods for determining platelet count and platelet function
US20040001826A1 (en) * 1999-06-30 2004-01-01 Millennium Pharmaceuticals, Inc. Glycoprotein VI and uses thereof
US7291714B1 (en) * 1999-06-30 2007-11-06 Millennium Pharmaceuticals, Inc. Glycoprotein VI and uses thereof
US6245527B1 (en) 1999-06-30 2001-06-12 Millennium Pharmaceuticals, Inc. Nucleic acid molecules encoding glycoprotein VI and recombinant uses thereof
US6586259B1 (en) * 1999-11-15 2003-07-01 Pharmanetics Incorporated Platelet/leukocyte interaction assay and reagent therefor
US6699677B1 (en) 1999-12-20 2004-03-02 Chemocentryx, Inc. Tethered ligands and methods of use
JP4643783B2 (ja) * 1999-12-24 2011-03-02 一般財団法人化学及血清療法研究所 フォンヴィルブランド因子を主成分とする血小板減少に伴う出血疾患の予防・治療用医薬組成物
DE10013377A1 (de) 2000-03-17 2001-09-20 Dade Behring Marburg Gmbh Induzierte Aggregation und Agglutination von Plättchen
WO2001096868A2 (en) * 2000-06-12 2001-12-20 Sysmex Corporation Immunoassay and immunoassay apparatus
DE10038900A1 (de) * 2000-08-09 2002-03-07 Haemosys Gmbh Einfache Methode zum drug monitoring von GPIIb/IIIa-Rezeptor-Antagonisten
EP1370874A2 (de) * 2001-01-24 2003-12-17 Accumetrics, Inc. Verfahren zur bestimmung der plättchen-aktivität unter verwendung von anti-plättchen-zusammensetzungen
US6746872B2 (en) * 2002-01-16 2004-06-08 Lifescan, Inc. Control compositions and methods of use for coagulation tests
US20040131500A1 (en) * 2002-01-18 2004-07-08 Chow Herbert S. Device and method for evaluating platelets
ATE491945T1 (de) * 2003-05-12 2011-01-15 Ulrich Pachmann Verfahren zur bestimmung des vorhandenseins von thrombozyteninhibitoren in einer blutprobe
US7790362B2 (en) * 2003-07-08 2010-09-07 Accumetrics, Inc. Controlled platelet activation to monitor therapy of ADP antagonists
US20070243632A1 (en) * 2003-07-08 2007-10-18 Coller Barry S Methods for measuring platelet reactivity of patients that have received drug eluting stents
US7566701B2 (en) 2004-09-07 2009-07-28 Archemix Corp. Aptamers to von Willebrand Factor and their use as thrombotic disease therapeutics
EP1789096A4 (de) 2004-09-07 2009-07-08 Archemix Corp Aptamere für den von-willebrand-faktor und ihre verwendung als therapeutika für thrombotische erkrankungen
KR20070101226A (ko) 2004-09-07 2007-10-16 아케믹스 코포레이션 앱타머의 약화학
US7595169B2 (en) * 2005-04-27 2009-09-29 Accumetrics, Inc. Method for determining percent platelet aggregation
US7205115B2 (en) * 2005-04-28 2007-04-17 Accumetrics, Inc. Method and system for stabilization of arachidonic acid for use in platelet function assay
US8066961B2 (en) * 2005-07-20 2011-11-29 Corning Incorporated Kinematic wellplate mounting method
EP2316858A1 (de) 2006-01-03 2011-05-04 TTO Nord AS Zubereitung und verfahren zur behandlung der Alloimmunen Thrombozytopenie von Neugeborenen (NAIT)
EP2150248A4 (de) 2007-01-16 2011-06-29 Univ Johns Hopkins Glutamat-rezeptorantagonisten und anwendungsverfahren
CN101675342A (zh) * 2007-05-03 2010-03-17 阿库米特里克斯股份有限公司 测量凝血酶受体拮抗剂对血小板聚集的抑制的方法
US20090305315A1 (en) * 2008-06-09 2009-12-10 Kent Raphael Gandola Hubbed dual cannula device for closed container sampling systems
US8448499B2 (en) 2008-12-23 2013-05-28 C A Casyso Ag Cartridge device for a measuring system for measuring viscoelastic characteristics of a sample liquid, a corresponding measuring system, and a corresponding method
US20110165595A1 (en) * 2009-07-13 2011-07-07 Catanzaro Brian E Apparatus and methods for processing a whole blood sample
US10816559B2 (en) 2014-09-29 2020-10-27 Ca Casyso Ag Blood testing system and method
US10539579B2 (en) 2014-09-29 2020-01-21 C A Casyso Gmbh Blood testing system and method
CN105717263B (zh) * 2016-03-04 2018-01-26 北京乐普医疗科技有限责任公司 一种检测噻吩并吡啶类抗血小板药物疗效的试剂卡及其使用方法和应用
EP3438667B1 (de) * 2017-08-02 2020-12-30 Siemens Healthcare Diagnostics Products GmbH Bindungstest zur diagnose einer heparin-induzierten thrombozytopenie
US20220373566A1 (en) * 2019-10-17 2022-11-24 Nova Biomedical Corporation Coagulation assay apparatus and methods thereof
US12543980B2 (en) 2021-06-21 2026-02-10 Instrumentation Laboratory Company Determining a platelet aggregation value
CN114720705A (zh) * 2022-04-20 2022-07-08 中国科学院苏州生物医学工程技术研究所 基于微球的血小板聚集功能检测质控品及质控方法
CN119291207B (zh) * 2024-08-30 2026-04-17 北京睿瑧生物技术有限公司 一种用于测定血小板数量的组合物、装置及检测方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4717654A (en) * 1984-06-19 1988-01-05 Akzo N.V. Process for solid phase platelet antibody assay
US5275812A (en) * 1985-06-07 1994-01-04 The General Hospital Corporation Method of treatment for myocardial infarction
US5114842A (en) * 1987-07-08 1992-05-19 The Scripps Research Institute Peptides and antibodies that inhibit platelet adhesion
EP0371258B1 (de) * 1988-11-23 1995-03-01 Cytec Technology Corp. Poröse Oberflächen-hydratisierte Substrate aus Polyacrylnitril, wie Perlderivate, Verfahren zu deren Herstellung und Verfahren zur Verwendung
CA2016061A1 (en) * 1989-05-08 1990-11-08 Laurence Wu-Kwang Chang Surface modified polyacrylonitrile substrates
US5246832A (en) * 1990-06-20 1993-09-21 University Of Massachusetts Medical Center Platelet analysis in whole blood
US5196309A (en) * 1990-11-15 1993-03-23 The Scripps Research Institute Characterization of platelet aggregation disorders
US5266462A (en) * 1992-06-03 1993-11-30 Baxter Diagnostics Inc. Measurement of platelet activities
US5427913A (en) * 1992-12-03 1995-06-27 Alberta Cancer Board Methods for determining platelet function
GB9306053D0 (en) * 1993-03-24 1993-05-12 Nycomed Pharma As Method and assay
US5455228A (en) * 1993-07-02 1995-10-03 The Research Foundation Of State University Of New York Peptidase resistant thrombin receptor peptide ligand
IL106330A (en) * 1993-07-14 1998-01-04 Univ Ramot Method and instrument for determining the activity of their plaques in the initial coagulation system
US5455288A (en) * 1994-01-26 1995-10-03 Needham; Donald G. Dustless color concentrate granules
WO1995027209A1 (en) * 1994-03-31 1995-10-12 The Trustees Of The University Of Pennsylvania Method and kit for detection of thrombin receptor activation of platelets and other cells

Also Published As

Publication number Publication date
IL115431A (en) 1999-10-28
US5763199A (en) 1998-06-09
DE69506434T2 (de) 1999-06-10
CA2201283A1 (en) 1996-04-11
GR3029470T3 (en) 1999-05-28
ES2127563T3 (es) 1999-04-16
AU3720095A (en) 1996-04-26
CA2201283C (en) 2004-05-18
DK0783696T3 (da) 1999-08-16
EP0783696B1 (de) 1998-12-02
EP0783696A1 (de) 1997-07-16
US5854005A (en) 1998-12-29
WO1996010749A1 (en) 1996-04-11
DE69506434D1 (de) 1999-01-14
IL115431A0 (en) 1996-01-31
JPH10506988A (ja) 1998-07-07

Similar Documents

Publication Publication Date Title
ATE174122T1 (de) Blutplättchen blockade test
Niiya et al. Increased surface expression of the membrane glycoprotein IIb/IIIa complex induced by platelet activation. Relationship to the binding of fibrinogen and platelet aggregation
EP1012604A4 (de) Agglutrimetrische versuche im blut
Moroi et al. Platelet receptors for collagen
NO890981D0 (no) Peptider og antistoffer som inhiberer blodplateadhesjon.
ATE78098T1 (de) Testverfahren mit oberflaechengebundenem fibrinogen und loesliches markiertes fibrinogen.
ATE203828T1 (de) Bestimmung der plättchenzahl unter verwendung eines plättchen-körnchenproteins
Dempfle et al. The fibrin assay comparison trial (FACT): correlation of soluble fibrin assays with D-dimer
Erdoes et al. Viscoelastic coagulation testing: use and current limitations in perioperative decision-making
ATE162632T1 (de) Messung von blutplättchenaktivitäten
Greilich et al. Quantitative assessment of platelet function and clot structure in patients with severe coronary artery disease
Hoots et al. A naturally occurring antibody that inhibits fibrin polymerization
ATE536889T1 (de) Kontrollierte thrombozyten-aktivierung zur überwachung der behandlung von adp-antagonisten
COURTOIS et al. Expression of intracellular fibrinogen on the surface of stimulated platelets
Goto et al. Synergistic effect of epinephrine and shearing on platelet activation
DE59107797D1 (de) Verfahren zum Nachweis von phosphoryliertes Tyrosin enthaltenden Proteinen
Lak et al. Evaluation of rFVIIa (NovoSeven) in Glanzmann patients with thromboelastogram
Hantgan et al. von Willebrand factor competes with fibrin for occupancy of GPIIb: IIIa on thrombin-stimulated platelets
Heilmann et al. Fluorescein derivatization of fibrinogen for flow cytometric analysis of fibrinogen binding to platelets
ATE250084T1 (de) Typ i prokollagen aminoterminales propeptid, dessen antikörper und testverfahren unter verwendung davon
Suzuki et al. Immunocytochemical aspects of platelet membrane glycoproteins and adhesive proteins during activation
Yu et al. Microfluidic hemophilia models using blood from healthy donors
Lepäntalo et al. Variability in platelet responses to collagen—comparison between whole blood perfusions, traditional platelet function tests and PFA-100
Xiong et al. Analysis of individual platelet-derived microparticles, comparing flow cytometry and capillary electrophoresis with laser-induced fluorescence detection
Amirkhosravi et al. Determination of tumor cell procoagulant activity by Sonoclot™ analysis in whole blood

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee