ATE175207T1 - Intrazelluläre inhibitoren der aldose-reduktase - Google Patents

Intrazelluläre inhibitoren der aldose-reduktase

Info

Publication number
ATE175207T1
ATE175207T1 AT93925050T AT93925050T ATE175207T1 AT E175207 T1 ATE175207 T1 AT E175207T1 AT 93925050 T AT93925050 T AT 93925050T AT 93925050 T AT93925050 T AT 93925050T AT E175207 T1 ATE175207 T1 AT E175207T1
Authority
AT
Austria
Prior art keywords
aldose reductase
intracellular inhibitors
intrinsic
reductase inhibitor
intracellular
Prior art date
Application number
AT93925050T
Other languages
English (en)
Inventor
Peter F Kador
Yukio Takahashi
Tomoyuki Terada
Libaniel Rodriguez
Matteo Schaffhauser
Original Assignee
Us Health
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Us Health filed Critical Us Health
Application granted granted Critical
Publication of ATE175207T1 publication Critical patent/ATE175207T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4703—Inhibitors; Suppressors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT93925050T 1992-10-26 1993-10-26 Intrazelluläre inhibitoren der aldose-reduktase ATE175207T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US96697092A 1992-10-26 1992-10-26

Publications (1)

Publication Number Publication Date
ATE175207T1 true ATE175207T1 (de) 1999-01-15

Family

ID=25512135

Family Applications (1)

Application Number Title Priority Date Filing Date
AT93925050T ATE175207T1 (de) 1992-10-26 1993-10-26 Intrazelluläre inhibitoren der aldose-reduktase

Country Status (8)

Country Link
US (3) US5560936A (de)
EP (1) EP0686164B1 (de)
JP (1) JPH08502967A (de)
AT (1) ATE175207T1 (de)
AU (1) AU676235B2 (de)
CA (1) CA2147494A1 (de)
DE (1) DE69322882T2 (de)
WO (1) WO1994010206A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0686164B1 (de) * 1992-10-26 1998-12-30 THE GOVERNMENT OF THE UNITED STATES OF AMERICA as represented by the SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES Intrazelluläre inhibitoren der aldose-reduktase
US5695785A (en) * 1996-06-27 1997-12-09 Masonic Medical Research Laboratory Kidney extract for treatment of systematic lupus erythematosus
US6555573B2 (en) * 2000-12-21 2003-04-29 The Quigley Corporation Method and composition for the topical treatment of diabetic neuropathy
CN1526023B (zh) * 2001-03-30 2012-09-05 香港中文大学 针对醛糖还原酶基因的引物和探针在制备用于确定白内障风险的组合物中的应用
EP1298223A3 (de) * 2001-09-28 2003-07-23 Pfizer Products Inc. Methoden die mit der A-C Wiederholungs-Z-Sequenz stromaufwärts des Aldosereduktasegens in Zusammenhang stehen
CN100522241C (zh) * 2002-09-10 2009-08-05 Scil技术股份有限公司 在低氧气浓度下用骨诱导蛋白包被的金属植入物
US6989167B2 (en) * 2003-06-25 2006-01-24 Procter + Gamble Co. Method for reducing acrylamide in foods comprising reducing the level of reducing sugars, foods having reduced levels of acrylamide, and article of commerce

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5646897A (en) * 1979-09-26 1981-04-28 Seiichi Shibata Novel glycopeptide
US5153211A (en) * 1983-09-14 1992-10-06 Alcon Laboratories, Inc. Spiro-tricyclicaromatic succinimide derivatives as inhibitors of aldose reductase
JPS6413019A (en) * 1987-06-09 1989-01-17 Tsumura & Co Aldose reductase inhibitor
IT1223302B (it) * 1987-09-16 1990-09-19 Baldacci Lab Spa Composti solfonamido derivati inibitori del sistema enzimatico aldoso-reduttasi e composizioni farmaceutiche che li contengono
JPH01121221A (ja) * 1987-11-02 1989-05-12 Toyo Pharma- Kk アルドース還元酵素阻害剤
JPH02225485A (ja) * 1989-02-27 1990-09-07 Taiho Yakuhin Kogyo Kk チエノピリミジン―３―酢酸誘導体
JPH0495025A (ja) * 1990-08-08 1992-03-27 Asahi Chem Ind Co Ltd アルドースリダクターゼ阻害剤
EP0686164B1 (de) * 1992-10-26 1998-12-30 THE GOVERNMENT OF THE UNITED STATES OF AMERICA as represented by the SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES Intrazelluläre inhibitoren der aldose-reduktase
US7966970B2 (en) * 2005-07-19 2011-06-28 M Management-Tex, Llc Dairy inflation

Also Published As

Publication number Publication date
AU676235B2 (en) 1997-03-06
US5928670A (en) 1999-07-27
CA2147494A1 (en) 1994-05-11
DE69322882T2 (de) 1999-08-19
US5738878A (en) 1998-04-14
AU5450894A (en) 1994-05-24
EP0686164A1 (de) 1995-12-13
WO1994010206A1 (en) 1994-05-11
DE69322882D1 (de) 1999-02-11
JPH08502967A (ja) 1996-04-02
EP0686164B1 (de) 1998-12-30
US5560936A (en) 1996-10-01

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties