ATE175998T1 - Rekombinierte alkalische phosphatase aus kälberdarm - Google Patents

Rekombinierte alkalische phosphatase aus kälberdarm

Info

Publication number
ATE175998T1
ATE175998T1 AT93907388T AT93907388T ATE175998T1 AT E175998 T1 ATE175998 T1 AT E175998T1 AT 93907388 T AT93907388 T AT 93907388T AT 93907388 T AT93907388 T AT 93907388T AT E175998 T1 ATE175998 T1 AT E175998T1
Authority
AT
Austria
Prior art keywords
alkaline phosphatase
recombined
calf
interest
calf intestinal
Prior art date
Application number
AT93907388T
Other languages
English (en)
Inventor
Jose L Millan
Original Assignee
Jolla Cancer Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jolla Cancer Res Found filed Critical Jolla Cancer Res Found
Application granted granted Critical
Publication of ATE175998T1 publication Critical patent/ATE175998T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/42—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving phosphatase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/535—Production of labelled immunochemicals with enzyme label or co-enzymes, co-factors, enzyme inhibitors or enzyme substrates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AT93907388T 1992-03-10 1993-03-10 Rekombinierte alkalische phosphatase aus kälberdarm ATE175998T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US84921992A 1992-03-10 1992-03-10

Publications (1)

Publication Number Publication Date
ATE175998T1 true ATE175998T1 (de) 1999-02-15

Family

ID=25305337

Family Applications (1)

Application Number Title Priority Date Filing Date
AT93907388T ATE175998T1 (de) 1992-03-10 1993-03-10 Rekombinierte alkalische phosphatase aus kälberdarm

Country Status (7)

Country Link
US (2) US5707853A (de)
EP (2) EP0584343B1 (de)
AT (1) ATE175998T1 (de)
CA (1) CA2102294A1 (de)
DE (1) DE69323131T2 (de)
DK (1) DK0584343T3 (de)
WO (1) WO1993018139A1 (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19819962A1 (de) 1998-05-05 1999-11-11 Roche Diagnostics Gmbh Hochaktive alkalische Phosphatase
US7888372B2 (en) * 2001-03-23 2011-02-15 National Institutes Of Health (Nih) Compositions and methods for modulating bone mineral deposition
US20020183276A1 (en) * 2001-03-23 2002-12-05 Burnham Institute Compositions and methods for modulating bone mineral deposition
DE10213201A1 (de) * 2002-03-25 2003-10-16 Roche Diagnostics Gmbh Erzeugung von schwach aktiven oder inaktiven Mutanten von Alkalischer Phosphatase und deren Expression in Hefe
BR0316465A (pt) * 2002-11-22 2005-10-11 Wyeth Corp Composição para o tratamento de infecções por chlamydia e métodos para indentificar as mesmas
CN100429312C (zh) * 2003-02-24 2008-10-29 新英格兰生物实验室公司 一种热敏磷酸酶的过量表达、纯化和表征
JP4999467B2 (ja) 2004-02-04 2012-08-15 ファルマアウェア セプシス ビー．ブイ． 粘膜関門に存在するｌｐｓを解毒するためのアルカリホスファターゼの使用
US8129168B2 (en) 2009-01-14 2012-03-06 Affymetrix, Inc. Recombinant colwellia psychrerythraea alkaline phosphatase and uses thereof
CA2937328C (en) 2014-01-24 2022-09-27 Am-Pharma B.V. Chimeric alkaline phosphatase-like proteins
ES2810813T3 (es) 2014-01-24 2021-03-09 Am Pharma Bv Procesamiento para recuperación y purificación de una fosfatasa alcalina
CN105802979B (zh) * 2016-04-01 2019-09-06 郑州科蒂亚生物技术有限公司 一种小牛肠碱性磷酸酶的表达载体及表达方法
US20190351071A1 (en) * 2016-11-11 2019-11-21 Dnalite Therapeutics, Inc. Structures and methods for gene therapy
WO2018175413A1 (en) * 2017-03-21 2018-09-27 Synthetic Biologics, Inc. Alkaline phosphatase formulations
WO2019069977A1 (ja) 2017-10-03 2019-04-11 キッコーマン株式会社 アルカリホスファターゼの製造方法及びそれを用いて得られるアルカリホスファターゼ、並びにその製造のためのベクター及び形質転換体
US11338020B2 (en) 2018-01-09 2022-05-24 Synthetic Biologics, Inc. Alkaline phosphatase agents for treatment of neurodevelopmental disorders
ES3032290T3 (en) 2018-03-20 2025-07-16 Theriva Biologics Inc Intestinal alkaline phosphatase formulations
US11654184B2 (en) 2018-03-20 2023-05-23 Theriva Biologics, Inc. Alkaline phosphatase agents for treatment of radiation disorders
CA3103443A1 (en) * 2018-06-18 2019-12-26 Synthetic Biologics, Inc. Methods of making alkaline phosphatase agents
JP7402429B2 (ja) * 2018-09-25 2023-12-21 東レ株式会社 アルカリホスファターゼ組成物並びに脱リン酸化核酸及び標識化核酸の製造方法
JP7660523B2 (ja) 2019-05-06 2025-04-11 セリバ・バイオロジクス・インコーポレイテッド アルカリリン酸塩に基づいた癌治療
JP7510787B2 (ja) 2020-05-28 2024-07-04 シスメックス株式会社 アルカリフォスファターゼ融合抗体及びその製造方法、並びに免疫測定用試薬及び免疫測定方法
CN113621079B (zh) * 2021-09-07 2023-04-11 金标优尼科(无锡)生物科技有限公司 Fab抗体与小牛肠碱性磷酸酶的融合蛋白及其制备方法

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD246686A (de) *
DE298424C (de) *
DE159993C (de) *
DE246686C (de) *
DD159993B1 (de) * 1981-06-29 1987-05-13 Anton Horn Immunosorbentchromatographische reinigung von alkalischer phosphatase aus kaelberdarm
US5084379A (en) * 1983-04-29 1992-01-28 Biowhittaker, Inc. Fluorometric assay of chymopapain hypersensitivity and reagents therefor
US4707438A (en) * 1984-08-22 1987-11-17 Tel Aviv University Immunoassay for breast cancer employing monoclonal antibodies
FI71433C (fi) * 1985-05-14 1986-12-19 Orion Yhtymae Oy Apparat foer immunokemisk bestaemning
EP0205404B1 (de) * 1985-06-11 1992-07-15 Ciba-Geigy Ag Hybrid-Interferone
JP2564540B2 (ja) * 1987-04-01 1996-12-18 株式会社日立製作所 免疫分析方法
US5204244A (en) * 1987-10-27 1993-04-20 Oncogen Production of chimeric antibodies by homologous recombination
GB8800078D0 (en) * 1988-01-05 1988-02-10 Ciba Geigy Ag Novel antibodies
US5089424A (en) * 1988-06-14 1992-02-18 Abbott Laboratories Method and apparatus for heterogeneous chemiluminescence assay
US5079171A (en) * 1988-09-15 1992-01-07 Adeza Biomedical Corporation Determining pregnancy induced hypertension and eclampsia by immunoassay of cellular fibronectin
US5079170A (en) * 1989-05-18 1992-01-07 Quidel Corporation Method of sample transfer using a filter applicator
DD298424A5 (de) * 1989-11-22 1992-02-20 Universitaet Leipzig,De Verfahren zur gewinnung von alkalischer phosphatase aus kaelberdarm

Also Published As

Publication number Publication date
WO1993018139A1 (en) 1993-09-16
DE69323131T2 (de) 1999-09-16
CA2102294A1 (en) 1993-09-11
EP0584343B1 (de) 1999-01-20
EP0584343A4 (en) 1996-03-20
EP0867511A1 (de) 1998-09-30
US5707853A (en) 1998-01-13
DE69323131D1 (de) 1999-03-04
DK0584343T3 (da) 1999-09-13
EP0584343A1 (de) 1994-03-02
US5773226A (en) 1998-06-30

Similar Documents

Publication Publication Date Title
ATE175998T1 (de) Rekombinierte alkalische phosphatase aus kälberdarm
ES2072452T3 (es) Medios cosmeticos desodorizantes.
FI872432A0 (fi) Indirekt kolorimetrisk bestaemning av en analyt i ett prov med hjaelp av ljussignalers foerhaollande.
NO822199L (no) Vaskemiddelforbindelser og -blandinger.
DE69016900D1 (de) Analysator von Isotopenzusammensetzungen.
FI852981A0 (fi) Anordning foer kemiska analyser och anvaendning daerav.
DE3752141D1 (de) Mittel zur behandlung von neuropathie
DE69030653D1 (de) Träger für Duftstoffproben
ATE158300T1 (de) Neue 7-beta-substituierte-4-aza-5-alpha-cholestan-on n als inhibitoren 5-alpha-reduktases
IT8124237A0 (it) Sega e procedimento per la sua fabbricazione.
DE3484588D1 (de) Schaltung zur erfassung von pruefeingaben.
DE69003977D1 (de) Verfahren und Einrichtung zur Bestimmung des Stengelgehaltes von Tabak.
BG45042A3 (bg) Метод за получаване на ацилирани дикетонови съединения
DE59208032D1 (de) Funktioneller Test und Reagenz zur Bestimmung von Fibrinogen
DK0486515T3 (da) Fremgangsmåde til bestemmelse af den funktionelle aktivitet af frit protein S eller protein C i en plasmaprøve
DE3866016D1 (de) Mos-transistor-brueckenschaltung.
DK0770876T3 (da) En screening-fremgangsmåde til at identificere ligander for målproteiner
AT376583B (de) Einrichtung zur behandlung von verbrennungsgasen aus verbrennungsanlagen
DK403384D0 (da) Enteralt effektivt, biologisk aktivt peptid- eller proteinmiddel ogfremgangsmaader til fremstilling deraf
NO822609L (no) Stabiliseringsmetode.
DE3485376D1 (de) Elektroneneinschlag-ionenquelle zur analysierung von komponenten.
TR199801027T2 (xx) Epitelyom te�his ve tedavisi i�in y�ntem.
FR2690519B1 (fr) Dispositif permettant d'analyser la trajectoire des mobiles.
IL95863A0 (en) Anticoagulant peptides and compositions containing them
FI852588L (fi) Analys av material ur borrhaol.