ATE178074T1 - Proinsulin-peptid-verbindungen für den nachweis und die behandlung von typ-i-diabetes - Google Patents

Proinsulin-peptid-verbindungen für den nachweis und die behandlung von typ-i-diabetes

Info

Publication number: ATE178074T1
Authority: AT; Austria
Prior art keywords: proinsulin; type; diabetes; peptide compounds; proinsulin peptide
Prior art date: 1994-07-08

Application number

AT95926642T

Other languages

English (en)

Inventor

William F Hickey

Ann C Griffin

Original Assignee

Dartmouth College

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-07-08

Filing date

1995-07-07

Publication date

1999-04-15

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26955374&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE178074(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1995-07-07 Application filed by Dartmouth College filed Critical Dartmouth College

1999-04-15 Application granted granted Critical

1999-04-15 Publication of ATE178074T1 publication Critical patent/ATE178074T1/de

Links

108010076181 Proinsulin Proteins 0.000 title abstract 9
150000001875 compounds Chemical class 0.000 title abstract 7
108090000765 processed proteins & peptides Proteins 0.000 title abstract 7
206010067584 Type 1 diabetes mellitus Diseases 0.000 title abstract 4
238000001514 detection method Methods 0.000 title 1
230000028993 immune response Effects 0.000 abstract 2
108010075254 C-Peptide Proteins 0.000 abstract 1
210000001744 T-lymphocyte Anatomy 0.000 abstract 1
238000003556 assay Methods 0.000 abstract 1
206010012601 diabetes mellitus Diseases 0.000 abstract 1
230000002401 inhibitory effect Effects 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70539—MHC-molecules, e.g. HLA-molecules
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/62—Insulins
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5091—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/575—Hormones
- G01N2333/62—Insulins

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Immunology (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Diabetes (AREA)
Hematology (AREA)
Biochemistry (AREA)
Cell Biology (AREA)
Genetics & Genomics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biophysics (AREA)
Urology & Nephrology (AREA)
Gastroenterology & Hepatology (AREA)
Endocrinology (AREA)
Zoology (AREA)
Biomedical Technology (AREA)
Toxicology (AREA)
Veterinary Medicine (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Physiology (AREA)
Chemical Kinetics & Catalysis (AREA)
Tropical Medicine & Parasitology (AREA)
Obesity (AREA)
Biotechnology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Microbiology (AREA)
Emergency Medicine (AREA)
Food Science & Technology (AREA)
Physics & Mathematics (AREA)
Analytical Chemistry (AREA)
General Physics & Mathematics (AREA)

AT95926642T 1994-07-08 1995-07-07 Proinsulin-peptid-verbindungen für den nachweis und die behandlung von typ-i-diabetes ATE178074T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US27222094A	1994-07-08	1994-07-08
US47270495A	1995-06-06	1995-06-06

Publications (1)

Publication Number	Publication Date
ATE178074T1 true ATE178074T1 (de)	1999-04-15

Family

ID=26955374

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT95926642T ATE178074T1 (de)	1994-07-08	1995-07-07	Proinsulin-peptid-verbindungen für den nachweis und die behandlung von typ-i-diabetes

Country Status (12)

Country	Link
US (1)	US20030220229A1 (de)
EP (1)	EP0788512B1 (de)
JP (1)	JPH10505821A (de)
CN (1)	CN1157621A (de)
AT (1)	ATE178074T1 (de)
AU (1)	AU3094795A (de)
CA (1)	CA2194548A1 (de)
DE (1)	DE69508605T2 (de)
DK (1)	DK0788512T3 (de)
ES (1)	ES2130629T3 (de)
MX (1)	MX9700198A (de)
WO (1)	WO1996001846A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0815136B1 (de)	1995-02-20	2007-06-13	The Walter And Eliza Hall Institute Of Medical Research	Immunoreaktive und immunotherapeutische moleküle welche in individuen mit insulin-abhängiger diabetes mellitus interagieren
SE520392C2 (sv)	1996-09-27	2003-07-01	Creative Peptides Sweden Ab C	Specifika peptider för behandling av diabetes mellitus
AUPO269996A0 (en) *	1996-10-01	1996-10-24	Walter And Eliza Hall Institute Of Medical Research, The	A method of prophylaxis and treatment
ES2331342B1 (es) *	2006-05-22	2010-10-13	Consejo Superior Investg.Cientificas	Uso de la proinsulina para la elaboracion de una composicion farmaceutica neuroprotectora, composicion terapeutica que la contiene y sus aplicaciones.
CN103630692B (zh) *	2013-06-02	2015-05-06	马鞍山国声生物技术有限公司	快速检测尿液c肽的胶体金免疫层析试剂盒及其检测方法
WO2015057968A2 (en) *	2013-10-17	2015-04-23	The General Hospital Corporation	Methods of identifying subjects responsive to treatment for an autoimmune disease and compositions for treating the same
GB2559499A (en) *	2014-02-25	2018-08-08	Orban Tihamer	Immunomodulatory therapy for type 1 diabetes mellitus autoimmunity
GB2523399B (en)	2014-02-25	2019-03-13	Orban Tihamer	A composition comprising ten overlapping peptide fragments of the entire preproinsulin sequence
GB201913408D0 (en) *	2019-09-17	2019-10-30	King S College London	Proinsulin peptides for type 1 diabetes
WO2025035125A1 (en) *	2023-08-10	2025-02-13	The Curators Of The University Of Missouri	Suppression of type 1 diabetes by intrathymic il-4

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS5210872B2 (de) *	1973-07-14	1977-03-26
US4308181A (en) *	1980-12-08	1981-12-29	American Home Products Corporation	Polypeptide compositions
US4652548A (en) *	1981-08-27	1987-03-24	Eli Lilly And Company	Pharmaceutical formulations comprising human insulin, human C-peptide, and human proinsulin
US5114844A (en) *	1989-03-14	1992-05-19	Yeda Research And Development Co., Ltd.	Diagnosis and treatment of insulin dependent diabetes mellitus
NL9001083A (nl) *	1990-05-04	1991-12-02	Rijksuniversiteit	Beta-cel antigeen.
ATE144326T1 (de) *	1990-08-17	1996-11-15	Univ Florida	Verfahren und komposition zum frühnachweiss und behandlung insulinabhängiger diabetes

1995
- 1995-07-07 MX MX9700198A patent/MX9700198A/es not_active IP Right Cessation
- 1995-07-07 DK DK95926642T patent/DK0788512T3/da active
- 1995-07-07 AT AT95926642T patent/ATE178074T1/de not_active IP Right Cessation
- 1995-07-07 EP EP95926642A patent/EP0788512B1/de not_active Revoked
- 1995-07-07 CN CN95194541A patent/CN1157621A/zh active Pending
- 1995-07-07 WO PCT/US1995/008596 patent/WO1996001846A1/en not_active Ceased
- 1995-07-07 CA CA002194548A patent/CA2194548A1/en not_active Abandoned
- 1995-07-07 JP JP8504435A patent/JPH10505821A/ja not_active Ceased
- 1995-07-07 ES ES95926642T patent/ES2130629T3/es not_active Expired - Lifetime
- 1995-07-07 DE DE69508605T patent/DE69508605T2/de not_active Expired - Fee Related
- 1995-07-07 AU AU30947/95A patent/AU3094795A/en not_active Abandoned
2003
- 2003-01-16 US US10/346,563 patent/US20030220229A1/en not_active Abandoned

Also Published As

Publication number	Publication date
EP0788512A1 (de)	1997-08-13
DK0788512T3 (da)	1999-10-11
JPH10505821A (ja)	1998-06-09
DE69508605D1 (de)	1999-04-29
US20030220229A1 (en)	2003-11-27
CN1157621A (zh)	1997-08-20
MX9700198A (es)	1997-04-30
EP0788512B1 (de)	1999-03-24
WO1996001846A1 (en)	1996-01-25
DE69508605T2 (de)	1999-07-22
CA2194548A1 (en)	1996-01-25
AU3094795A (en)	1996-02-09
ES2130629T3 (es)	1999-07-01

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Legal Events

Date	Code	Title
1999-11-15	UEP	Publication of translation of european patent specification
2006-04-15	REN	Ceased due to non-payment of the annual fee
2008-11-15	RZN	Patent revoked