ATE178651T1 - Expression von osteogenem faktor op-1 in mit rekombinantem baculovirus infizierten spodoptera frugiperda-zellen - Google Patents

Expression von osteogenem faktor op-1 in mit rekombinantem baculovirus infizierten spodoptera frugiperda-zellen

Info

Publication number: ATE178651T1
Authority: AT; Austria
Prior art keywords: recombinant baculovirus; pct; recombinant; spodoptera frugiperda; present
Prior art date: 1992-01-27

Application number

AT93902252T

Other languages

English (en)

Inventor

Ombretta Stanchi

Alessandro Negro

Lanfranco Callegaro

Original Assignee

Murst Italian

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-01-27

Filing date

1993-01-27

Publication date

1999-04-15

1993-01-27 Application filed by Murst Italian filed Critical Murst Italian

1999-04-15 Application granted granted Critical

1999-04-15 Publication of ATE178651T1 publication Critical patent/ATE178651T1/de

Links

241000701447 unidentified baculovirus Species 0.000 title abstract 4
241000256251 Spodoptera frugiperda Species 0.000 title abstract 2
230000002188 osteogenic effect Effects 0.000 title abstract 2
108010049870 Bone Morphogenetic Protein 7 Proteins 0.000 abstract 4
102100022544 Bone morphogenetic protein 7 Human genes 0.000 abstract 4
241000238631 Hexapoda Species 0.000 abstract 2
108091028043 Nucleic acid sequence Proteins 0.000 abstract 2
238000000034 method Methods 0.000 abstract 2
208000020084 Bone disease Diseases 0.000 abstract 1
108020004414 DNA Proteins 0.000 abstract 1
101000899361 Homo sapiens Bone morphogenetic protein 7 Proteins 0.000 abstract 1
108020004511 Recombinant DNA Proteins 0.000 abstract 1
210000000988 bone and bone Anatomy 0.000 abstract 1
238000012258 culturing Methods 0.000 abstract 1
230000007547 defect Effects 0.000 abstract 1
201000010099 disease Diseases 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
102000046107 human BMP7 Human genes 0.000 abstract 1
208000014674 injury Diseases 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1
230000000399 orthopedic effect Effects 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
102000004169 proteins and genes Human genes 0.000 abstract 1
108090000623 proteins and genes Proteins 0.000 abstract 1
230000008733 trauma Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/51—Bone morphogenetic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Biophysics (AREA)
Medicinal Chemistry (AREA)
Zoology (AREA)
Biochemistry (AREA)
Toxicology (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Gastroenterology & Hepatology (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Orthopedic Medicine & Surgery (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

AT93902252T 1992-01-27 1993-01-27 Expression von osteogenem faktor op-1 in mit rekombinantem baculovirus infizierten spodoptera frugiperda-zellen ATE178651T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
ITPD920007A IT1259042B (it)	1992-01-27	1992-01-27	Preparazione di vettori di espressione per la sintesi del polipeptide chiamato fattore osteogenetico op-1 in cellule eucariotiche di spodoptera frugiperda via infezione con baculovirus ricombinante

Publications (1)

Publication Number	Publication Date
ATE178651T1 true ATE178651T1 (de)	1999-04-15

Family

ID=11389773

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT93902252T ATE178651T1 (de)	1992-01-27	1993-01-27	Expression von osteogenem faktor op-1 in mit rekombinantem baculovirus infizierten spodoptera frugiperda-zellen

Country Status (7)

Country	Link
US (1)	US5641649A (de)
EP (1)	EP0625198B1 (de)
AT (1)	ATE178651T1 (de)
DE (1)	DE69324345T2 (de)
ES (1)	ES2134254T3 (de)
IT (1)	IT1259042B (de)
WO (1)	WO1993015197A2 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5610021A (en) *	1992-02-21	1997-03-11	Creative Biomolecules, Inc.	Compositions and methods for identification and use of soluble complex forms of osteogenic proteins
WO1994020539A1 (en) *	1993-03-04	1994-09-15	Creative Biomolecules, Inc.	Method and compositions for recombinant osteogenic protein production
CA2124422A1 (en) *	1993-05-27	1994-11-28	Yukio Fujisawa	Heterodimers of tgf-.beta. superfamily
KR970043049A (ko) *	1995-12-28	1997-07-26	성재갑	효모를 이용한 골 생성 단백질- 1의 제조방법
US20010016646A1 (en) *	1998-03-20	2001-08-23	David C. Rueger	Osteogenic devices and methods of use thereof for repair of endochondral bone, osteochondral and chondral defects
US7041641B2 (en) *	1997-03-20	2006-05-09	Stryker Corporation	Osteogenic devices and methods of use thereof for repair of endochondral bone and osteochondral defects
US6949357B2 (en) *	1997-06-05	2005-09-27	Abbott Laboratories	Reagents and methods useful for detecting diseases of the urinary tract
WO2008014054A2 (en) *	2006-07-27	2008-01-31	Centocor, Inc.	Bmp-7 variant compositions, methods and uses

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ATE78293T1 (de) *	1983-05-27	1992-08-15	Texas A & M Univ Sys	Verfahren zur herstellung eines rekombinanten baculovirus-expressionsvektors.
US5221620A (en) *	1987-10-06	1993-06-22	Oncogen	Cloning and expression of transforming growth factor β2
CA2005120A1 (en) *	1988-12-15	1990-06-15	Anthony F. Purchio	Tgf-beta 1/beta 2: a novel chimeric transforming growth factor-beta
ES2113857T3 (es) *	1989-03-28	1998-05-16	Genetics Inst	Composiciones osteoinductoras.
US5155037A (en) *	1989-08-04	1992-10-13	The Texas A&M University System	Insect signal sequences useful to improve the efficiency of processing and secretion of foreign genes in insect systems
ES2118723T3 (es) *	1989-10-17	1998-10-01	Stryker Corp	Dispositivos osteogenicos.
GB9023111D0 (en) *	1990-10-24	1990-12-05	Wellcome Found	Expression system

1992
- 1992-01-27 IT ITPD920007A patent/IT1259042B/it active IP Right Grant
1993
- 1993-01-27 ES ES93902252T patent/ES2134254T3/es not_active Expired - Lifetime
- 1993-01-27 AT AT93902252T patent/ATE178651T1/de not_active IP Right Cessation
- 1993-01-27 US US08/256,368 patent/US5641649A/en not_active Expired - Lifetime
- 1993-01-27 EP EP93902252A patent/EP0625198B1/de not_active Expired - Lifetime
- 1993-01-27 WO PCT/EP1993/000183 patent/WO1993015197A2/en not_active Ceased
- 1993-01-27 DE DE69324345T patent/DE69324345T2/de not_active Expired - Lifetime

Also Published As

Publication number	Publication date
IT1259042B (it)	1996-03-11
US5641649A (en)	1997-06-24
EP0625198B1 (de)	1999-04-07
EP0625198A1 (de)	1994-11-23
ITPD920007A0 (it)	1992-01-27
WO1993015197A2 (en)	1993-08-05
DE69324345T2 (de)	1999-11-25
DE69324345D1 (de)	1999-05-12
ITPD920007A1 (it)	1993-07-27
ES2134254T3 (es)	1999-10-01
WO1993015197A3 (en)	1993-09-16

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Legal Events

Date	Code	Title	Description
1999-10-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties