ITPD920007A1 - Preparazione di vettori di espressione per la sintesi del polipeptide chiamato fattore osteogenetico op-1 in cellule eucariotiche di spodoptera frugiperda via infezione con baculovirus ricombinante - Google Patents

Preparazione di vettori di espressione per la sintesi del polipeptide chiamato fattore osteogenetico op-1 in cellule eucariotiche di spodoptera frugiperda via infezione con baculovirus ricombinante

Info

Publication number: ITPD920007A1
Authority: IT; Italy
Prior art keywords: recombinant baculovirus; pct; preparation; recombinant; spodoptera frugiperda
Prior art date: 1992-01-27

Application number

IT000007A

Other languages

English (en)

Inventor

Lanfranco Callegaro

Alessandro Negro

Ombretta Stanchi

Original Assignee

Mini Ricerca Scient Tecnolog

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-01-27

Filing date

1992-01-27

Publication date

1993-07-27

1992-01-27 Application filed by Mini Ricerca Scient Tecnolog filed Critical Mini Ricerca Scient Tecnolog

1992-01-27 Priority to ITPD920007A priority Critical patent/IT1259042B/it

1992-01-27 Publication of ITPD920007A0 publication Critical patent/ITPD920007A0/it

1993-01-27 Priority to ES93902252T priority patent/ES2134254T3/es

1993-01-27 Priority to US08/256,368 priority patent/US5641649A/en

1993-01-27 Priority to AT93902252T priority patent/ATE178651T1/de

1993-01-27 Priority to DE69324345T priority patent/DE69324345T2/de

1993-01-27 Priority to PCT/EP1993/000183 priority patent/WO1993015197A2/en

1993-01-27 Priority to EP93902252A priority patent/EP0625198B1/en

1993-07-27 Publication of ITPD920007A1 publication Critical patent/ITPD920007A1/it

1996-03-11 Application granted granted Critical

1996-03-11 Publication of IT1259042B publication Critical patent/IT1259042B/it

Links

241000701447 unidentified baculovirus Species 0.000 title abstract 4
241000256251 Spodoptera frugiperda Species 0.000 title abstract 2
238000002360 preparation method Methods 0.000 title abstract 2
230000015572 biosynthetic process Effects 0.000 title 1
239000000969 carrier Substances 0.000 title 1
230000014509 gene expression Effects 0.000 title 1
208000015181 infectious disease Diseases 0.000 title 1
230000002642 osteogeneic effect Effects 0.000 title 1
229920001184 polypeptide Polymers 0.000 title 1
102000004196 processed proteins & peptides Human genes 0.000 title 1
108090000765 processed proteins & peptides Proteins 0.000 title 1
238000003786 synthesis reaction Methods 0.000 title 1
108010049870 Bone Morphogenetic Protein 7 Proteins 0.000 abstract 4
102100022544 Bone morphogenetic protein 7 Human genes 0.000 abstract 4
241000238631 Hexapoda Species 0.000 abstract 2
108091028043 Nucleic acid sequence Proteins 0.000 abstract 2
238000000034 method Methods 0.000 abstract 2
208000020084 Bone disease Diseases 0.000 abstract 1
108020004414 DNA Proteins 0.000 abstract 1
101000899361 Homo sapiens Bone morphogenetic protein 7 Proteins 0.000 abstract 1
108020004511 Recombinant DNA Proteins 0.000 abstract 1
210000000988 bone and bone Anatomy 0.000 abstract 1
238000012258 culturing Methods 0.000 abstract 1
230000007547 defect Effects 0.000 abstract 1
201000010099 disease Diseases 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
102000046107 human BMP7 Human genes 0.000 abstract 1
208000014674 injury Diseases 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1
230000000399 orthopedic effect Effects 0.000 abstract 1
230000002188 osteogenic effect Effects 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
102000004169 proteins and genes Human genes 0.000 abstract 1
108090000623 proteins and genes Proteins 0.000 abstract 1
230000008733 trauma Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/51—Bone morphogenetic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Biophysics (AREA)
Medicinal Chemistry (AREA)
Zoology (AREA)
Biochemistry (AREA)
Toxicology (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Gastroenterology & Hepatology (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Orthopedic Medicine & Surgery (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

ITPD920007A 1992-01-27 1992-01-27 Preparazione di vettori di espressione per la sintesi del polipeptide chiamato fattore osteogenetico op-1 in cellule eucariotiche di spodoptera frugiperda via infezione con baculovirus ricombinante IT1259042B (it)

Priority Applications (7)

Application Number	Priority Date	Filing Date	Title
ITPD920007A IT1259042B (it)	1992-01-27	1992-01-27	Preparazione di vettori di espressione per la sintesi del polipeptide chiamato fattore osteogenetico op-1 in cellule eucariotiche di spodoptera frugiperda via infezione con baculovirus ricombinante
ES93902252T ES2134254T3 (es)	1992-01-27	1993-01-27	Expresion del factor osteogenico op-1 de celulas de spodoptera frugiperda infectadas con baculovirus recombinante.
US08/256,368 US5641649A (en)	1992-01-27	1993-01-27	Expression of osteogenic factor OP-1 in cells of spodoptera frugiperda infected with recombinant baculovirus
AT93902252T ATE178651T1 (de)	1992-01-27	1993-01-27	Expression von osteogenem faktor op-1 in mit rekombinantem baculovirus infizierten spodoptera frugiperda-zellen
DE69324345T DE69324345T2 (de)	1992-01-27	1993-01-27	Expression von osteogenem faktor op-1 in mit rekombinantem baculovirus infizierten spodoptera frugiperda-zellen
PCT/EP1993/000183 WO1993015197A2 (en)	1992-01-27	1993-01-27	Expression of osteogenic factor op-1 in cells of spodoptera frugiperda infected with recombinant baculovirus
EP93902252A EP0625198B1 (en)	1992-01-27	1993-01-27	Expression of osteogenic factor op-1 in cells of spodoptera frugiperda infected with recombinant baculovirus

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
ITPD920007A IT1259042B (it)	1992-01-27	1992-01-27	Preparazione di vettori di espressione per la sintesi del polipeptide chiamato fattore osteogenetico op-1 in cellule eucariotiche di spodoptera frugiperda via infezione con baculovirus ricombinante

Publications (3)

Publication Number	Publication Date
ITPD920007A0 ITPD920007A0 (it)	1992-01-27
ITPD920007A1 true ITPD920007A1 (it)	1993-07-27
IT1259042B IT1259042B (it)	1996-03-11

Family

ID=11389773

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ITPD920007A IT1259042B (it)	1992-01-27	1992-01-27	Preparazione di vettori di espressione per la sintesi del polipeptide chiamato fattore osteogenetico op-1 in cellule eucariotiche di spodoptera frugiperda via infezione con baculovirus ricombinante

Country Status (7)

Country	Link
US (1)	US5641649A (it)
EP (1)	EP0625198B1 (it)
AT (1)	ATE178651T1 (it)
DE (1)	DE69324345T2 (it)
ES (1)	ES2134254T3 (it)
IT (1)	IT1259042B (it)
WO (1)	WO1993015197A2 (it)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5610021A (en) *	1992-02-21	1997-03-11	Creative Biomolecules, Inc.	Compositions and methods for identification and use of soluble complex forms of osteogenic proteins
CA2157387C (en) *	1993-03-04	1998-12-15	David C. Rueger	Method and compositions for recombinant osteogenic protein production
EP0626451A3 (en) *	1993-05-27	1997-11-05	Takeda Chemical Industries, Ltd.	Heterodimers of a TGF-beta superfamily
KR970043049A (ko) *	1995-12-28	1997-07-26	성재갑	효모를 이용한 골 생성 단백질- 1의 제조방법
US20010016646A1 (en) *	1998-03-20	2001-08-23	David C. Rueger	Osteogenic devices and methods of use thereof for repair of endochondral bone, osteochondral and chondral defects
US7041641B2 (en) *	1997-03-20	2006-05-09	Stryker Corporation	Osteogenic devices and methods of use thereof for repair of endochondral bone and osteochondral defects
CA2292759A1 (en) *	1997-06-05	1998-12-10	Abbott Laboratories	Reagents and methods useful for detecting diseases of the urinary tract
WO2008014054A2 (en) *	2006-07-27	2008-01-31	Centocor, Inc.	Bmp-7 variant compositions, methods and uses

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0127839B1 (en) *	1983-05-27	1992-07-15	THE TEXAS A&M UNIVERSITY SYSTEM	Method for producing a recombinant baculovirus expression vector
US5221620A (en) *	1987-10-06	1993-06-22	Oncogen	Cloning and expression of transforming growth factor β2
CA2005120A1 (en) *	1988-12-15	1990-06-15	Anthony F. Purchio	Tgf-beta 1/beta 2: a novel chimeric transforming growth factor-beta
ATE162223T1 (de) *	1989-03-28	1998-01-15	Genetics Inst	Osteoinduktive zusammensetzungen
US5155037A (en) *	1989-08-04	1992-10-13	The Texas A&M University System	Insect signal sequences useful to improve the efficiency of processing and secretion of foreign genes in insect systems
WO1991005802A1 (en) *	1989-10-17	1991-05-02	Creative Biomolecules, Inc.	Osteogenic devices
GB9023111D0 (en) *	1990-10-24	1990-12-05	Wellcome Found	Expression system

1992
- 1992-01-27 IT ITPD920007A patent/IT1259042B/it active IP Right Grant
1993
- 1993-01-27 WO PCT/EP1993/000183 patent/WO1993015197A2/en not_active Ceased
- 1993-01-27 AT AT93902252T patent/ATE178651T1/de not_active IP Right Cessation
- 1993-01-27 ES ES93902252T patent/ES2134254T3/es not_active Expired - Lifetime
- 1993-01-27 EP EP93902252A patent/EP0625198B1/en not_active Expired - Lifetime
- 1993-01-27 US US08/256,368 patent/US5641649A/en not_active Expired - Lifetime
- 1993-01-27 DE DE69324345T patent/DE69324345T2/de not_active Expired - Lifetime

Also Published As

Publication number	Publication date
EP0625198B1 (en)	1999-04-07
EP0625198A1 (en)	1994-11-23
DE69324345T2 (de)	1999-11-25
ATE178651T1 (de)	1999-04-15
ITPD920007A0 (it)	1992-01-27
WO1993015197A3 (en)	1993-09-16
ES2134254T3 (es)	1999-10-01
WO1993015197A2 (en)	1993-08-05
US5641649A (en)	1997-06-24
IT1259042B (it)	1996-03-11
DE69324345D1 (de)	1999-05-12

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Legal Events

Date	Code	Title	Description
1996-03-11	0001	Granted
1999-10-27	TA	Fee payment date (situation as of event date), data collected since 19931001	Effective date: 19990210