ATE178717T1 - Immobilisierung von reagenzien für spezifische bindungsassay - Google Patents

Immobilisierung von reagenzien für spezifische bindungsassay

Info

Publication number
ATE178717T1
ATE178717T1 AT94910108T AT94910108T ATE178717T1 AT E178717 T1 ATE178717 T1 AT E178717T1 AT 94910108 T AT94910108 T AT 94910108T AT 94910108 T AT94910108 T AT 94910108T AT E178717 T1 ATE178717 T1 AT E178717T1
Authority
AT
Austria
Prior art keywords
specific binding
reagents
immobilization
binding assay
solid phase
Prior art date
Application number
AT94910108T
Other languages
English (en)
Inventor
Spencer H Lin
Kwok Sum Yu
Pratap Singh
Steven E Diamond
Original Assignee
Dade Behring Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dade Behring Inc filed Critical Dade Behring Inc
Application granted granted Critical
Publication of ATE178717T1 publication Critical patent/ATE178717T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306—Solid-phase reaction mechanisms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/544—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic
    • G01N33/545—Synthetic resin
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/551—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being inorganic
    • G01N33/552—Glass or silica
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/815—Test for named compound or class of compounds
    • Y10S436/817—Steroids or hormones
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/823—Immunogenic carrier or carrier per se
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/81—Carrier - bound or immobilized peptides or proteins and the preparation thereof, e.g. biological cell or cell fragment as carrier
    • Y10S530/811—Peptides or proteins is immobilized on, or in, an inorganic carrier

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AT94910108T 1993-02-24 1994-02-09 Immobilisierung von reagenzien für spezifische bindungsassay ATE178717T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US2192893A 1993-02-24 1993-02-24

Publications (1)

Publication Number Publication Date
ATE178717T1 true ATE178717T1 (de) 1999-04-15

Family

ID=21806909

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94910108T ATE178717T1 (de) 1993-02-24 1994-02-09 Immobilisierung von reagenzien für spezifische bindungsassay

Country Status (11)

Country Link
US (1) US5861319A (de)
EP (1) EP0637385B1 (de)
JP (1) JP3366978B2 (de)
AT (1) ATE178717T1 (de)
AU (1) AU6267794A (de)
CA (1) CA2133967A1 (de)
DE (1) DE69417645T2 (de)
ES (1) ES2132392T3 (de)
MX (1) MX9401387A (de)
WO (1) WO1994019693A1 (de)
ZA (1) ZA941084B (de)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5898005A (en) * 1993-02-24 1999-04-27 Dade Behring Inc. Rapid detection of analytes with receptors immobilized on soluble submicron particles
US6121056A (en) * 1993-02-24 2000-09-19 Dade Behring Inc. Random detection of antigens with antibodies immobilized on soluble submicron particles
US6083708A (en) * 1995-08-11 2000-07-04 Dade Behring Inc. Polypeptide: dendrimer complexes
US6117631A (en) * 1996-10-29 2000-09-12 Polyprobe, Inc. Detection of antigens via oligonucleotide antibody conjugates
US6133436A (en) 1996-11-06 2000-10-17 Sequenom, Inc. Beads bound to a solid support and to nucleic acids
AU4562599A (en) * 1998-06-12 1999-12-30 New Horizons Diagnostics, Inc. Colloidal colorimetric flow through and lateral flow assays utilizing soluble submicron particles
US6404500B1 (en) * 1999-01-25 2002-06-11 Aqua Check Systems, Inc Colorimeter apparatus and related process
US6471968B1 (en) 2000-05-12 2002-10-29 Regents Of The University Of Michigan Multifunctional nanodevice platform
KR100377946B1 (ko) * 2000-07-15 2003-03-29 한국과학기술원 덴드리머를 이용한 단분자막의 제조방법
US7501157B2 (en) * 2001-06-26 2009-03-10 Accelr8 Technology Corporation Hydroxyl functional surface coating
US6844028B2 (en) * 2001-06-26 2005-01-18 Accelr8 Technology Corporation Functional surface coating
US20030108972A1 (en) * 2001-12-06 2003-06-12 Zweig Stephen Eliot Tethered receptor-ligand reagent and assay
US9671396B2 (en) * 2001-09-05 2017-06-06 Joon Won Park Solid substrate comprising array of dendrons and methods for using the same
DE10332849A1 (de) * 2003-07-18 2005-02-17 Sustech Gmbh & Co. Kg Arrays immobilisierter Biomoleküle auf Hydrogel-bildenden Oberflächen, deren Herstellung und deren Verwendung
US7754500B2 (en) * 2003-11-21 2010-07-13 Anp Technologies, Inc. Asymmetrically branched polymer conjugates and microarray assays
EP1796537A4 (de) * 2004-08-25 2012-03-07 Univ Michigan Dendrimer-basierte zusammensetzungen und verfahren zu ihrer verwendung
WO2006102484A2 (en) * 2005-03-21 2006-09-28 Anp Technologies, Inc. Symmetrically branched polymer conjugates and microarray assays
CA2606815C (en) * 2005-05-02 2017-03-07 Anp Technologies, Inc. Polymer conjugate enhanced bioassays
US20070015166A1 (en) * 2005-07-14 2007-01-18 Nilsen Thor W Lateral flow methods and devices for detection of nucleic acid binding proteins
US20070041934A1 (en) * 2005-08-12 2007-02-22 Regents Of The University Of Michigan Dendrimer based compositions and methods of using the same
US8492098B2 (en) 2006-02-21 2013-07-23 The Trustees Of Tufts College Methods and arrays for target analyte detection and determination of reaction components that affect a reaction
ES2736148T3 (es) * 2006-02-21 2019-12-26 Mipsalus Aps Preparación mejorada de polímeros con impresión molecular
AU2008275501A1 (en) * 2007-04-19 2009-01-15 The Regents Of The University Of Michigan Dendrimer based compositions and methods of using the same
WO2009151687A2 (en) 2008-03-12 2009-12-17 The Regents Of The University Of Michigan Dendrimer conjugates
DE102008018180A1 (de) * 2008-04-02 2009-10-15 Hansgrohe Ag Verfahren zum Nachweis von perfluorierten Tensiden
WO2010039861A2 (en) 2008-09-30 2010-04-08 The Regents Of The University Of Michigan Dendrimer conjugates
WO2010054321A2 (en) 2008-11-07 2010-05-14 The Regents Of The University Of Michigan Methods of treating autoimmune disorders and/or inflammatory disorders
CA2777682C (en) 2009-10-13 2015-02-24 The Regents Of The University Of Michigan Dendrimer compositions and methods of synthesis
WO2011059586A2 (en) 2009-10-30 2011-05-19 The Regents Of The University Of Michigan Multifunctional small molecules
US8114197B2 (en) * 2009-12-22 2012-02-14 Hollingsworth & Vose Company Filter media and articles including dendrimers and/or other components
KR102007997B1 (ko) 2011-02-07 2019-08-07 라이프 테크놀로지스 코포레이션 감수성 화합물을 안정화시키는 조성물 및 방법
US9402911B2 (en) 2011-12-08 2016-08-02 The Regents Of The University Of Michigan Multifunctional small molecules
KR20200109293A (ko) 2017-09-13 2020-09-22 프로제너티, 인크. 자간전증 바이오마커 및 관련된 시스템 및 방법
WO2021113710A1 (en) 2019-12-04 2021-06-10 Progenity, Inc. Assessment of preeclampsia using assays for free and dissociated placental growth factor
JP7436838B2 (ja) * 2020-05-20 2024-02-22 藤倉化成株式会社 抗体-デンドリマー複合体を用いるヘモグロビンA1cの測定方法

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4363634A (en) * 1980-07-18 1982-12-14 Akzona Incorporated Glass support coated with synthetic polymer for bioprocess
US4517288A (en) * 1981-01-23 1985-05-14 American Hospital Supply Corp. Solid phase system for ligand assay
US4444879A (en) * 1981-01-29 1984-04-24 Science Research Center, Inc. Immunoassay with article having support film and immunological counterpart of analyte
US4507466A (en) * 1983-01-07 1985-03-26 The Dow Chemical Corporation Dense star polymers having core, core branches, terminal groups
US4568737A (en) * 1983-01-07 1986-02-04 The Dow Chemical Company Dense star polymers and dendrimers
US5482830A (en) * 1986-02-25 1996-01-09 Biostar, Inc. Devices and methods for detection of an analyte based upon light interference
US5468606A (en) * 1989-09-18 1995-11-21 Biostar, Inc. Devices for detection of an analyte based upon light interference
US4694064A (en) * 1986-02-28 1987-09-15 The Dow Chemical Company Rod-shaped dendrimer
ES2054678T5 (es) * 1986-08-18 1997-09-16 Dow Chemical Co Conjugados estrella.
US5338532A (en) * 1986-08-18 1994-08-16 The Dow Chemical Company Starburst conjugates
US5364613A (en) * 1989-04-07 1994-11-15 Sieving Paul F Polychelants containing macrocyclic chelant moieties
US5914095A (en) * 1989-04-07 1999-06-22 Salutar, Inc. Polychelants containg amide bonds
US5541057A (en) * 1989-09-18 1996-07-30 Biostar, Inc. Methods for detection of an analyte
US5171264A (en) 1990-02-28 1992-12-15 Massachusetts Institute Of Technology Immobilized polyethylene oxide star molecules for bioapplications
US5418136A (en) * 1991-10-01 1995-05-23 Biostar, Inc. Devices for detection of an analyte based upon light interference
EP1126278B1 (de) * 1992-07-31 2007-05-23 Inverness Medical - BioStar Inc. Vorrichtungen und Verfahren zur Detektion eines Analyten mittels optischer Interferenz

Also Published As

Publication number Publication date
MX9401387A (es) 1994-08-31
EP0637385B1 (de) 1999-04-07
EP0637385A1 (de) 1995-02-08
JPH07506195A (ja) 1995-07-06
DE69417645D1 (de) 1999-05-12
DE69417645T2 (de) 1999-12-16
US5861319A (en) 1999-01-19
WO1994019693A1 (en) 1994-09-01
JP3366978B2 (ja) 2003-01-14
AU6267794A (en) 1994-09-14
ES2132392T3 (es) 1999-08-16
ZA941084B (en) 1995-08-17
CA2133967A1 (en) 1994-09-01

Similar Documents

Publication Publication Date Title
DE69417645D1 (de) Immobilisierung von reagenzien für spezifische bindungsassay
DE69521253D1 (de) Schnellnachweis von analyten mit auf löslichen submikron-teilchen immobilisierten rezeptoren
AU582293B2 (en) Heterogeneous specific binding assay employing an aggregatable binding reagent
ATE142340T1 (de) Universalbindefilm
SE9604575D0 (sv) Method and system for analyte determination
CA2215042A1 (en) Assay reagents and devices
NO941781L (no) Ikke-radioaktiv immunanalyse
ATE88762T1 (de) Methoden und zusammensetzungen fuer tests mit nukleinsaeuresonden.
KR970074793A (ko) 올리고머화된 수용체를 사용한 결정 방법
DE3485920D1 (de) Kolorimetrisches immunoessay auf fester oberflaeche, sowie dazu zu verwendender teststab und seine herstellung.
KR900002075A (ko) 특이적으로 결합가능한 물질의 정량 방법 및 시약
KR870009031A (ko) 폴리뉴클레오티드 서열 검출용 용액상 단일 혼성 분석법
DK516387A (da) Fremgangsmaade til immunometrisk bestemmelse
KR890006812A (ko) 메탐페타민에 대한 모노클로날 항체 그 모노클로날 항체의 제법 메탐페타민의 분석법 및 분석키트
CA2097545A1 (en) Process for the immunochemical determination of an analyte
DE58907087D1 (de) Verfahren zur Bestimmung von für ein Antigen klassenspezifischen Antikörpern und dazu geeignetes Reagenz.
WO2004076684A3 (en) Compositions and methods for the detection of mammalian muscle troponin i
Schmidt Jr et al. An advanced solid support for immunoassays and other affinity applications
ATE182172T1 (de) Immunologischer nachweis von metolachlor
ES2054686T3 (es) Equipo de inmunoensayo.
KR890006828A (ko) 효소 분석법
ES479985A1 (es) Un metodo mejorado para la deteccion y determinacion de un -acido biliar.
DE59606685D1 (de) Kompetitiver Immuntest unter Verwendung komplexierter Analytderivate
ES2055031T3 (es) Ensayo de enzima de preincubacion de receptor.
WO2001044499B1 (en) Modified labeled complement components for immunoassays

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties