ATE88762T1 - Methoden und zusammensetzungen fuer tests mit nukleinsaeuresonden. - Google Patents

Methoden und zusammensetzungen fuer tests mit nukleinsaeuresonden.

Info

Publication number
ATE88762T1
ATE88762T1 AT87905826T AT87905826T ATE88762T1 AT E88762 T1 ATE88762 T1 AT E88762T1 AT 87905826 T AT87905826 T AT 87905826T AT 87905826 T AT87905826 T AT 87905826T AT E88762 T1 ATE88762 T1 AT E88762T1
Authority
AT
Austria
Prior art keywords
probe
analyte
nucleic acid
support
derivatized
Prior art date
Application number
AT87905826T
Other languages
English (en)
Inventor
Thomas Raymond Gingeras
Soumitra Shankar Ghosh
Geneva Ruth Davis
Dobrah Yantis Kwoh
Gary Fred Musso
Original Assignee
Siska Diagnostics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Siska Diagnostics Inc filed Critical Siska Diagnostics Inc
Application granted granted Critical
Publication of ATE88762T1 publication Critical patent/ATE88762T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701Specific hybridization probes
    • C12Q1/702Specific hybridization probes for retroviruses
    • C12Q1/703Viruses associated with AIDS
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6832Enhancement of hybridisation reaction
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6834Enzymatic or biochemical coupling of nucleic acids to a solid phase

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • AIDS & HIV (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT87905826T 1986-08-11 1987-08-11 Methoden und zusammensetzungen fuer tests mit nukleinsaeuresonden. ATE88762T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US89575686A 1986-08-11 1986-08-11
EP87905826A EP0276302B1 (de) 1986-08-11 1987-08-11 Methoden und zusammensetzungen für tests mit nukleinsäuresonden
PCT/US1987/001966 WO1988001302A1 (en) 1986-08-11 1987-08-11 Nucleic acid probe assay methods and compositions

Publications (1)

Publication Number Publication Date
ATE88762T1 true ATE88762T1 (de) 1993-05-15

Family

ID=25405032

Family Applications (1)

Application Number Title Priority Date Filing Date
AT87905826T ATE88762T1 (de) 1986-08-11 1987-08-11 Methoden und zusammensetzungen fuer tests mit nukleinsaeuresonden.

Country Status (6)

Country Link
EP (1) EP0276302B1 (de)
JP (1) JP2641880B2 (de)
AT (1) ATE88762T1 (de)
CA (1) CA1308372C (de)
DE (1) DE3785658T2 (de)
WO (1) WO1988001302A1 (de)

Families Citing this family (173)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5118605A (en) * 1984-10-16 1992-06-02 Chiron Corporation Polynucleotide determination with selectable cleavage sites
US5367066A (en) * 1984-10-16 1994-11-22 Chiron Corporation Oligonucleotides with selectably cleavable and/or abasic sites
US6270961B1 (en) * 1987-04-01 2001-08-07 Hyseq, Inc. Methods and apparatus for DNA sequencing and DNA identification
US5202231A (en) * 1987-04-01 1993-04-13 Drmanac Radoje T Method of sequencing of genomes by hybridization of oligonucleotide probes
US5525464A (en) * 1987-04-01 1996-06-11 Hyseq, Inc. Method of sequencing by hybridization of oligonucleotide probes
GB8810400D0 (en) 1988-05-03 1988-06-08 Southern E Analysing polynucleotide sequences
US5700637A (en) * 1988-05-03 1997-12-23 Isis Innovation Limited Apparatus and method for analyzing polynucleotide sequences and method of generating oligonucleotide arrays
US7811751B2 (en) 1988-05-03 2010-10-12 Oxford Gene Technology Limited Analysing polynucleotide sequences
US6054270A (en) * 1988-05-03 2000-04-25 Oxford Gene Technology Limited Analying polynucleotide sequences
US5047523A (en) * 1988-08-02 1991-09-10 Ortho Diagnostic Systems Inc. Nucleic acid probe for detection of neisseria gonorrhoea
ATE168724T1 (de) * 1988-09-29 1998-08-15 Chiron Corp Nachweis eines polynukleotids durch ersätzung einer kette an einer fangsonde
US5324829A (en) * 1988-12-16 1994-06-28 Ortho Diagnostic Systems, Inc. High specific activity nucleic acid probes having target recognition and signal generating moieties
GR1000347B (el) * 1988-12-21 1992-06-25 Ortho Diagnostic Systems Inc Μεθοδος παραγωγης νουκλεοτιδικων ανιχνευτων χρησιμοποιωντας ενα συμπληρωμα γεφυρωσεως.
US5237016A (en) * 1989-01-05 1993-08-17 Siska Diagnostics, Inc. End-attachment of oligonucleotides to polyacrylamide solid supports for capture and detection of nucleic acids
US5514550A (en) * 1989-02-03 1996-05-07 Johnson & Johnson Clinical Diagnostics, Inc. Nucleic acid test article and its use to detect a predetermined nucleic acid
EP1715064B1 (de) 1989-06-02 2009-02-25 Institut Pasteur Nukleotid-Sequenzen von HIV-1, HIV-2 und SIV Retrovirusgenomen, ihre Verwendung zur Amplifizierung von pol-Sequenzen dieser Retroviren und zur In Vitro Diagnostik von diesen Viren verursachten Infektionen
FR2647810B1 (fr) * 1989-06-02 1994-07-22 Pasteur Institut Amorces oligonucleotidiques pour l'amplification du genome des retrovirus du type hiv-2 et siv, et leurs applications au diagnostic in vitro des infections dues a ces virus
US7022814B1 (en) 1992-01-21 2006-04-04 Institut Pasteur And Institut National De La Sante Et De La Recherche Medicale Nucleotide sequences derived from the genome of retroviruses of the HIV-1, HIV-2 and SIV type, and their uses in particular for the amplification of the genomes of these retroviruses and for the in vitro diagnosis of the diseases due to these viruses
FR2647809B1 (fr) * 1989-06-02 1991-09-20 Pasteur Institut Amorces oligonucleotidiques pour l'amplification du genome des retrovirus du type hiv-1, hiv-2 et siv, et leurs applications au diagnostic in vitro des infections dues a ces virus
US6955915B2 (en) 1989-06-07 2005-10-18 Affymetrix, Inc. Apparatus comprising polymers
US5547839A (en) 1989-06-07 1996-08-20 Affymax Technologies N.V. Sequencing of surface immobilized polymers utilizing microflourescence detection
US5744101A (en) 1989-06-07 1998-04-28 Affymax Technologies N.V. Photolabile nucleoside protecting groups
US6919211B1 (en) 1989-06-07 2005-07-19 Affymetrix, Inc. Polypeptide arrays
WO1991000868A1 (en) * 1989-07-07 1991-01-24 National Research Development Corporation Immobilised polynucleotides
US5856088A (en) * 1989-07-11 1999-01-05 Gen-Probe Incorporated Detection of human immunodeficiency virus type 1
CA2020958C (en) * 1989-07-11 2005-01-11 Daniel L. Kacian Nucleic acid sequence amplification methods
US6589734B1 (en) 1989-07-11 2003-07-08 Gen-Probe Incorporated Detection of HIV
US7049102B1 (en) 1989-09-22 2006-05-23 Board Of Trustees Of Leland Stanford University Multi-gene expression profile
US5215882A (en) * 1989-11-30 1993-06-01 Ortho Diagnostic Systems, Inc. Method of immobilizing nucleic acid on a solid surface for use in nucleic acid hybridization assays
US5474911A (en) * 1989-12-01 1995-12-12 The Board Of Trustees Of Leland Stanford Jr. University Promotion of high specificity molecular assembly
CA2031659A1 (en) * 1990-01-26 1991-07-27 John B. Findlay Water-insoluble reagent, nucleic acid probe, test kit and diagnostic and purification methods
US5695926A (en) * 1990-06-11 1997-12-09 Bio Merieux Sandwich hybridization assays using very short capture probes noncovalently bound to a hydrophobic support
FR2663040B1 (fr) * 1990-06-11 1995-09-15 Bio Merieux Procede de detection d'une sequence nucleotidique selon la technique d'hybridation sandwich.
IL99025A0 (en) * 1990-08-15 1992-07-15 Astra Ab Novel process for the detection of pathogens using dna probes
US5474895A (en) * 1990-11-14 1995-12-12 Siska Diagnostics Inc. Non-isotopic detection of nucleic acids using a polystyrene support-based sandwich hybridization assay and compositions useful therefor
CA2055755A1 (en) * 1990-11-22 1992-05-23 Toshihiko Kishimoto Method of immobilizing single-stranded dna on carrier at terminal
CA2065719A1 (en) 1991-04-30 1992-10-31 John B. Findlay Nucleic acid amplification and detection methods using rapid polymerase chain reaction cycle
US5976789A (en) * 1991-07-17 1999-11-02 Bio Merieux System of probes enabling HLA-DR typing to be performed, and typing method using said probes
FR2679255B1 (fr) * 1991-07-17 1993-10-22 Bio Merieux Procede d'immobilisation d'un fragment nucleique par fixation passive sur un support solide, support solide ainsi obtenu et son utilisation.
WO1993004199A2 (en) * 1991-08-20 1993-03-04 Scientific Generics Limited Methods of detecting or quantitating nucleic acids and of producing labelled immobilised nucleic acids
US6849462B1 (en) 1991-11-22 2005-02-01 Affymetrix, Inc. Combinatorial strategies for polymer synthesis
US6943034B1 (en) 1991-11-22 2005-09-13 Affymetrix, Inc. Combinatorial strategies for polymer synthesis
WO1993013223A1 (en) 1991-12-23 1993-07-08 Chiron Corporation Hiv probes for use in solution phase sandwich hybridization assays
US6300058B1 (en) 1992-01-29 2001-10-09 Hitachi Chemical Research Center, Inc. Method for measuring messenger RNA
CA2128891A1 (en) * 1992-01-29 1993-08-05 Cylia Keller Polynucleotide immobilized support
WO1994000600A1 (en) * 1992-06-25 1994-01-06 Microprobe Corporation Solid supports for nucleic acid hybridization assays
US5580971A (en) * 1992-07-28 1996-12-03 Hitachi Chemical Company, Ltd. Fungal detection system based on rRNA probes
WO1994002636A1 (en) * 1992-07-28 1994-02-03 Hitachi Chemical Company Ltd. Gene detection system
KR100325554B1 (ko) 1993-03-26 2002-11-02 젠-프로브 인코포레이티드 사람의면역결핍 바이러스타입1의검출
US7625697B2 (en) 1994-06-17 2009-12-01 The Board Of Trustees Of The Leland Stanford Junior University Methods for constructing subarrays and subarrays made thereby
US7323298B1 (en) 1994-06-17 2008-01-29 The Board Of Trustees Of The Leland Stanford Junior University Microarray for determining the relative abundances of polynuceotide sequences
GB9415129D0 (en) * 1994-07-27 1994-09-14 Lynxvale Ltd Oligonucleotides and their use
US6416714B1 (en) * 1995-04-25 2002-07-09 Discovery Partners International, Inc. Remotely programmable matrices with memories
US6017496A (en) 1995-06-07 2000-01-25 Irori Matrices with memories and uses thereof
US6284459B1 (en) 1995-04-25 2001-09-04 Discovery Partners International Solid support matrices with memories and combinatorial libraries therefrom
US6100026A (en) * 1995-04-25 2000-08-08 Irori Matrices with memories and uses thereof
US5961923A (en) * 1995-04-25 1999-10-05 Irori Matrices with memories and uses thereof
US5616465A (en) 1995-08-09 1997-04-01 The Regents Of The University Of California Detection and isolation of nucleic acid sequences using competitive hybridization probes
US6027879A (en) * 1995-08-09 2000-02-22 The Regents Of The University Of California Detection and isolation of nucleic acid sequences using a bifunctional hybridization probe
US5811253A (en) * 1995-09-01 1998-09-22 Johnson & Johnson Clinical Diagnostics, Inc. Use of vanadium bromoperoxidase as a signal-generating enzyme for chemiluminescent systems: test kits and analytical methods
US6013440A (en) 1996-03-11 2000-01-11 Affymetrix, Inc. Nucleic acid affinity columns
GB9624165D0 (en) * 1996-11-19 1997-01-08 Amdex A S Use of nucleic acids bound to carrier macromolecules
US6025133A (en) * 1996-12-30 2000-02-15 Gen-Probe Incorporated Promoter-sequestered oligonucleoside and method of use
US20020042048A1 (en) 1997-01-16 2002-04-11 Radoje Drmanac Methods and compositions for detection or quantification of nucleic acid species
US6309824B1 (en) 1997-01-16 2001-10-30 Hyseq, Inc. Methods for analyzing a target nucleic acid using immobilized heterogeneous mixtures of oligonucleotide probes
US6297006B1 (en) 1997-01-16 2001-10-02 Hyseq, Inc. Methods for sequencing repetitive sequences and for determining the order of sequence subfragments
US5837860A (en) * 1997-03-05 1998-11-17 Molecular Tool, Inc. Covalent attachment of nucleic acid molecules onto solid-phases via disulfide bonds
ES2271994T3 (es) 1997-05-02 2007-04-16 Gen-Probe Incorporated Hibridacion en dos pasos y captura de un polinucleotido.
US6534273B2 (en) 1997-05-02 2003-03-18 Gen-Probe Incorporated Two-step hybridization and capture of a polynucleotide
US5994076A (en) * 1997-05-21 1999-11-30 Clontech Laboratories, Inc. Methods of assaying differential expression
IT1297096B1 (it) * 1997-12-03 1999-08-03 Sorin Diagnostics S R L Metodo per la rivelazione di analiti di dna a singola elica
US6355419B1 (en) 1998-04-27 2002-03-12 Hyseq, Inc. Preparation of pools of nucleic acids based on representation in a sample
ES2322859T3 (es) 1998-05-01 2009-06-30 Gen-Probe Incorporated Analizador de diagnostico automatizado.
JP2002518060A (ja) * 1998-06-24 2002-06-25 グラクソ グループ リミテッド ヌクレオチド検出法
US6902891B2 (en) 1999-12-17 2005-06-07 Bio Merieux Process for labeling a nucleic acid
US6489114B2 (en) 1999-12-17 2002-12-03 Bio Merieux Process for labeling a ribonucleic acid, and labeled RNA fragments which are obtained thereby
FR2803913B1 (fr) 2000-01-13 2002-08-16 Pasteur Sanofi Diagnostics Procede d'immobilisation de reactif(s) affin(s) sur phase solide hydrophobe
AU2001274560A1 (en) * 2000-08-08 2002-02-18 Toyo Kohan Co. Ltd. Substrate activation kit and method of detecting dna or the like by using the same
DE60045932D1 (de) 2000-09-01 2011-06-16 Gen Probe Inc HIV-1-Sequenzverstärkung zur Erkennung von Sequenzen in Zusammenhang mit Wirkstoffresistenz-Mutationen
ATE386821T1 (de) 2000-10-23 2008-03-15 Gen Probe Inc Zusammensetzungen und methoden zur detektion von humanem immundefizienz virus 2 (hiv-2)
KR20050008720A (ko) 2002-05-17 2005-01-21 벡톤 디킨슨 앤드 컴퍼니 표적 핵산 서열의 분리, 증폭 및 검출을 위한 자동화 시스템
AU2003253651C1 (en) 2002-06-14 2010-06-03 Gen-Probe Incorporated Compositions and methods for detecting hepatitis B virus
CA2957200C (en) 2002-10-16 2020-05-26 Gen-Probe Incorporated Compositions and methods for detecting west nile virus
US7833714B1 (en) 2003-04-11 2010-11-16 Affymetrix, Inc. Combinatorial affinity selection
CA2547750C (en) 2003-12-19 2014-04-08 Gen-Probe Incorporated Compositions, methods and kits for detecting the nucleic acids of hiv-1 and hiv-2
AU2005262317B2 (en) 2004-07-13 2009-07-16 Gen-Probe Incorporated Compositions and methods for detection of hepatitis A virus nucleic acid
ES2759991T3 (es) 2004-09-30 2020-05-12 Gen Probe Inc Ensayo para detectar y cuantificar el VIH-1
CA2582661C (en) 2004-11-09 2015-08-11 Gen-Probe Incorporated Compositions and methods for detecting group a streptococci
US20060177859A1 (en) 2005-02-07 2006-08-10 Gen-Probe Incorporated Compositions and methods for detecting group B streptococci
CA2597319C (en) 2005-02-18 2014-09-30 Gen-Probe Incorporated Sample preparation method incorporating an alkaline shock
EP2471805A3 (de) 2005-05-06 2013-01-16 Gen-Probe Incorporated Zusammensetzungen und Verfahren zur spezifischen Detektion von Nukleinsäuren der Viren Influenza A oder B
CA2625414A1 (en) 2005-10-17 2007-04-26 Gen-Probe Incorporated Compositions and methods to detect legionella pneumophila nucleic acid
JP5071987B2 (ja) 2005-11-14 2012-11-14 ジェン−プロウブ インコーポレイテッド パラメトリック較正方法
US7588897B2 (en) 2006-05-12 2009-09-15 Gen-Probe Incorporated Compositions and methods to detect Enterococci nucleic acid
CA2673017C (en) 2006-12-21 2015-08-04 Gen-Probe Incorporated Methods and compositions for nucleic acid amplification
CA2715991A1 (en) 2007-12-26 2009-07-09 Gen-Probe Incorporated Amplification oligomers and methods to detect candida albicans 26s rrna or encoding dna
KR20090081260A (ko) * 2008-01-23 2009-07-28 삼성전자주식회사 마이크로 어레이 혼성화 검출 방법
EP3957754B1 (de) 2008-04-21 2026-01-28 Gen-Probe Incorporated Verfahren zur erkennung des chikungunya-virus
EP3118208A1 (de) 2009-02-26 2017-01-18 Gen-Probe Incorporated Assay zum nachweisen menschlicher parvovirennukleinsäure
EP2446057B1 (de) 2009-06-23 2014-11-19 Gen-Probe Incorporated Zusammensetzungen und verfahren für den nukleinsäurenachweis aus mollicutes
AU2010266234B2 (en) 2009-07-01 2013-07-25 Gen-Probe Incorporated Methods and compositions for nucleic acid amplification
WO2011103274A1 (en) 2010-02-17 2011-08-25 Gen-Probe Incorporated Compositions and methods to detect atopobium vaginae nucleic acid
WO2011133811A2 (en) 2010-04-21 2011-10-27 Gen-Probe Incorporated Compositions, methods and kits to detect herpes simplex virus nucleic acid
EP3305920B1 (de) 2010-07-12 2020-02-12 Gen-Probe Incorporated Zusammensetzungen und assays zur erkennung von saisonaler h3-influenza a-virus-nukleinsäure
EP2752247A3 (de) 2010-07-23 2016-08-31 Beckman Coulter, Inc. System oder Verfahren zur Aufnahme analytischer Einheiten
WO2012030856A2 (en) 2010-08-30 2012-03-08 Gen-Probe Incorporated Compositions, methods and reaction mixtures for the detection of xenotropic murine leukemia virus-related virus
EP2625297B1 (de) 2010-10-04 2018-10-10 Gen-Probe Prodesse, Inc. Zusammensetzungen, verfahren und kits für den nachweis von adenovirus-nukleinsäuren
AU2012249751B2 (en) 2011-04-25 2016-11-03 Gen-Probe Incorporated Compositions and methods for detecting BV-associated bacterial nucleic acid
WO2013012708A1 (en) 2011-07-15 2013-01-24 Gen-Probe Incorporated Compositions and method for detecting human parvovirus nucleic acid and for detecting hepatitis a virus nucleic acids in single-plex or multiplex assays
AU2012304327B2 (en) 2011-09-08 2015-07-09 Gen-Probe Incorporated Compositions and methods for detecting BV-associated bacterial nucleic acid
KR20140092378A (ko) 2011-11-07 2014-07-23 베크만 컬터, 인코포레이티드 샘플을 처리하기 위한 시스템 및 방법
JP6190380B2 (ja) 2011-11-07 2017-08-30 ベックマン コールター, インコーポレイテッド 等分機システムおよびワークフロー
BR112014011044A2 (pt) 2011-11-07 2017-04-25 Beckman Coulter Inc amortecimento magnético para sistema de transporte de espécime
US9046506B2 (en) 2011-11-07 2015-06-02 Beckman Coulter, Inc. Specimen container detection
JP6320926B2 (ja) 2011-11-07 2018-05-09 ベックマン コールター, インコーポレイテッド 遠心分離機システムおよびワークフロー
JP6165755B2 (ja) 2011-11-07 2017-07-19 ベックマン コールター, インコーポレイテッド ロボットアーム
DE102011120550B4 (de) 2011-12-05 2013-11-07 Gen-Probe Prodesse, Inc. Zusammensetzungen, Verfahren und Kits zur Detektion von Adenovirusnukleinsäuren
US11098375B2 (en) 2012-02-24 2021-08-24 Gen-Probe Prodesse, Inc. Detection of Shiga toxin genes in bacteria
AU2013205110B2 (en) 2012-04-24 2016-10-13 Gen-Probe Incorporated Compositions, Methods and Kits to Detect Herpes Simplex Virus Nucleic Acids
AU2013205064B2 (en) 2012-06-04 2015-07-30 Gen-Probe Incorporated Compositions and Methods for Amplifying and Characterizing HCV Nucleic Acid
AU2013205087B2 (en) 2012-07-13 2016-03-03 Gen-Probe Incorporated Method for detecting a minority genotype
US9932628B2 (en) 2012-07-27 2018-04-03 Gen-Probe Incorporated Dual reference calibration method and system for quantifying polynucleotides
AU2013202808B2 (en) 2012-07-31 2014-11-13 Gen-Probe Incorporated System and method for performing multiplex thermal melt analysis
EP2890814B1 (de) 2012-08-30 2019-11-13 Gen-Probe Incorporated Mehrphasige nukleinsäureamplifikation
AU2013205122B2 (en) 2012-10-11 2016-11-10 Gen-Probe Incorporated Compositions and Methods for Detecting Human Papillomavirus Nucleic Acid
AU2013205090B2 (en) 2012-12-07 2016-07-28 Gen-Probe Incorporated Compositions and Methods for Detecting Gastrointestinal Pathogen Nucleic Acid
AU2013202805B2 (en) 2013-03-14 2015-07-16 Gen-Probe Incorporated System and method for extending the capabilities of a diagnostic analyzer
CA2899645C (en) 2013-03-15 2022-08-30 Gen-Probe Incorporated Calibration method, apparatus and computer program product
AU2014241191A1 (en) 2013-03-27 2015-10-22 Sample Technologies, Inc. Recombinant phage and bacterial detection methods
AU2014281406A1 (en) 2013-06-19 2016-01-21 Sample6 Technologies, Inc. Phage-based bacterial detection assay
AU2014306512C1 (en) 2013-08-14 2021-07-08 Gen-Probe Incorporated Compositions and methods for detecting HEV nucleic acid
AU2016205179B2 (en) 2015-01-09 2021-06-17 Gen-Probe Incorporated Methods and compositions for diagnosing bacterial vaginosis
AU2016233298B2 (en) 2015-03-16 2021-09-02 Gen-Probe Incorporated Methods and compositions for detecting bacterial nucleic acid and diagnosing bacterial vaginosis
CN108779499B (zh) 2016-01-04 2023-08-11 简·探针公司 用于检测念珠菌属物种的方法和组合物
EP3469103B1 (de) 2016-06-10 2021-10-06 Gen-Probe Incorporated Zusammensetzungen und verfahren für den nachweis von zikavirus-nukleinsäure
CA3040907A1 (en) 2016-10-19 2018-04-26 Gen-Probe Incorporated Compositions and methods for detecting or quantifying hepatitis c virus
EP4671386A3 (de) 2016-11-21 2026-04-15 Gen-Probe Incorporated Zusammensetzungen und verfahren zum nachweis oder zur quantifizierung des hepatitis-b-virus
EP4219771A3 (de) 2017-03-24 2023-08-16 Gen-Probe Incorporated Zusammensetzungen und verfahren für den multiplexnachweis viraler krankheitserreger in proben
EP4282985A3 (de) 2017-03-24 2024-02-28 Gen-Probe Incorporated Zusammensetzungen und verfahren zum nachweis oder zur quantifizierung des parainfluenzavirus
EP4276201A3 (de) 2017-06-07 2024-01-17 Gen-Probe Incorporated Nachweis von nukleinsäure der babesia-spezies in einer probe
CN111032209A (zh) 2017-07-10 2020-04-17 简·探针公司 分析系统和方法
CA3072452A1 (en) 2017-08-11 2019-02-14 Gen-Probe Incorporated Compositions and methods for detecting staphylococcus aureus
AU2018369872B2 (en) 2017-11-17 2022-11-24 Gen-Probe Incorporated Compositions and methods for detecting C1orf43 nucleic acid
EP3724354A1 (de) 2017-12-15 2020-10-21 Gen-Probe Incorporated Zusammensetzungen und verfahren zum nachweis von toxigenem clostridium difficile
EP3746225B1 (de) 2018-01-29 2024-10-30 Gen-Probe Incorporated Analytische systeme und verfahren
CN111684077B (zh) 2018-02-06 2024-10-11 简·探针公司 远红染料探针调配物
CA3103442A1 (en) 2018-06-13 2019-12-19 Gen-Probe Incorporated Compositions and methods for detecting group b streptococcus nucleic acid
JP7470095B2 (ja) 2018-07-10 2024-04-17 ジェン-プローブ・インコーポレーテッド 核酸を検出および定量するための方法およびシステム
US12227812B2 (en) 2018-08-01 2025-02-18 Gen-Probe Incorporated Compositions and methods for detecting nucleic acids of Epstein-Barr virus
AU2019319203B8 (en) 2018-08-08 2025-10-09 Gen-Probe Incorporated Compositions, methods and kits for detecting Mycoplasma genitalium
CA3107043A1 (en) 2018-08-21 2020-02-27 Gen-Probe Incorporated Compositions and methods for amplifying, detecting or quantifying human cytomegalovirus
KR102937202B1 (ko) 2018-08-24 2026-03-11 젠-프로브 인코포레이티드 세균성 핵산을 검출하고 세균성 질염을 진단하기 위한 조성물 및 방법
CA3112651A1 (en) 2018-09-27 2020-04-02 Gen-Probe Incorporated Compositions and methods for detecting bordetella pertussis and bordetella parapertussis nucleic acid
AU2019365821C1 (en) 2018-10-22 2025-08-14 Gen-Probe Incorporated Compositions and methods for amplifying, detecting or quantifying human polyomavirus BK virus
TW202030333A (zh) 2018-12-20 2020-08-16 美商簡 探針公司 用於檢測瘧原蟲物種核酸之組成物及方法
US20220080425A1 (en) 2018-12-31 2022-03-17 Gen-Probe Incorporated Tray for transfering solid reagents to a multi-well cartridge
US12210028B2 (en) 2019-05-03 2025-01-28 Gen-Probe Incorporated Receptacle delivery system
AU2020299621B2 (en) 2019-07-03 2025-10-30 Gen-Probe Incorporated Oligonucleotides for use in determining the presence of Trichomonas vaginalis in a sample.
AU2020335996A1 (en) 2019-08-23 2022-03-31 Gen-Probe Incorporated Compositions, methods and kits for detecting Treponema pallidum
WO2021046270A1 (en) 2019-09-05 2021-03-11 Gen-Probe Incorporated Detection of chlamydia trachomatis nucleic acid variants
EP4361284B1 (de) 2019-12-09 2025-09-10 Gen-Probe Incorporated Quantifizierung von polynukleotidanalyten aus getrockneten proben
AU2021230341C8 (en) 2020-03-04 2026-05-07 Gen-Probe Incorporated Compositions and methods for detecting SARS-CoV-2 nucleic acid
CN115698325A (zh) 2020-05-07 2023-02-03 盖立复诊断解决方案公司 用于检测SARS-CoV-2核酸的方法和组合物
CA3177256A1 (en) 2020-10-21 2022-04-28 Gen-Probe Incorporated Fluid container management system
CA3226812A1 (en) 2021-07-27 2023-02-02 Gen-Probe Incorporated Compositions and methods for detecting gastrointestinal pathogens
EP4282980A1 (de) 2022-05-23 2023-11-29 Mobidiag Oy Methoden zum verstärken einer nukleinsäure
WO2024054924A1 (en) 2022-09-08 2024-03-14 Gen-Probe Incorporated Method of detecting nucleic acid analytes using dual-specificity primers
WO2024161179A1 (en) 2023-01-31 2024-08-08 Mobidiag Oy Compositions and methods for detecting stx nucleic acids
EP4455303A1 (de) 2023-04-28 2024-10-30 Mobidiag Oy Kontrollen für nukleinsäureamplifikationsverfahren
EP4455304A1 (de) 2023-04-28 2024-10-30 Mobidiag Oy Kontrollen für nukleinsäureamplifikationsverfahren
EP4454758A1 (de) 2023-04-28 2024-10-30 Mobidiag Oy Kontrollen für nukleinsäureamplifikationsverfahren
AU2024267362A1 (en) 2023-05-05 2025-11-13 Gen-Probe Incorporated Method and system for improving specificity of analyte detection using real-time nucleic acid amplification
CN117960247B (zh) * 2024-01-31 2025-11-14 郑州大学 一种基于纳米酶氧化的隐性孔雀石绿快速检测方法及纳米酶的制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2277A (en) * 1841-09-30 Island
CA1083508A (fr) * 1975-11-13 1980-08-12 Jacques Grange Supports porteurs de chaines laterales, procedes d'obtention de ces supports, procedes de fixation de composes organiques comportant un residu glucidique sur lesdits supports, produits et reactifs resultant de ladite fixation chimique
US4302204A (en) * 1979-07-02 1981-11-24 The Board Of Trustees Of Leland Stanford Junior University Transfer and detection of nucleic acids
SE8003732L (sv) * 1980-05-19 1981-11-20 Pharmacia Diagnostics Ab Sett vid bestemningsmetoder involverande biospecifika affinitetsreaktioner
US4358535A (en) * 1980-12-08 1982-11-09 Board Of Regents Of The University Of Washington Specific DNA probes in diagnostic microbiology
CA1180647A (en) * 1981-07-17 1985-01-08 Cavit Akin Light-emitting polynucleotide hybridization diagnostic method
FI63596C (fi) * 1981-10-16 1983-07-11 Orion Yhtymae Oy Mikrobdiagnostiskt foerfarande som grundar sig pao skiktshybridisering av nukleinsyror och vid foerfarandet anvaenda kombinationer av reagenser
CA1222680A (en) * 1983-07-05 1987-06-09 Nanibhushan Dattagupta Testing dna samples for particular nucleotide sequences

Also Published As

Publication number Publication date
WO1988001302A1 (en) 1988-02-25
DE3785658T2 (de) 1993-08-12
DE3785658D1 (de) 1993-06-03
CA1308372C (en) 1992-10-06
JP2641880B2 (ja) 1997-08-20
EP0276302B1 (de) 1993-04-28
EP0276302A1 (de) 1988-08-03
EP0276302A4 (de) 1989-08-16
JPH01500461A (ja) 1989-02-16

Similar Documents

Publication Publication Date Title
DE3785658D1 (de) Methoden und zusammensetzungen fuer tests mit nukleinsaeuresonden.
DE69230864D1 (de) Verfahren zur immobilisierung von nukleinsäuresonden an polystyroloberflächen
CA1288709C (en) Immobilization of nucleic acids on derivatized nylon supports
US4994373A (en) Method and structures employing chemically-labelled polynucleotide probes
US6268141B1 (en) Immobilization of unmodified biopolymers to acyl fluoride activated substrates
US20100273145A1 (en) Assay method utilizing polynucleotide sequences
US7138268B2 (en) Dry biochemical assay plate and method for making the same
ES8707343A1 (es) Un metodo para aislar una secuencia de acido nucleico objetivo seleccionada
US4670380A (en) Assays utilizing labeled nucleic acid probes
ES2132392T3 (es) Inmovilizacion de reactivos de ensayo de enlace especifico.
DE3578349D1 (de) Hybridisierungstest fuer nukleinsaeure mittels anwendung von nachweisbaren anti-hybridantikoerpern.
ATE202213T1 (de) Schnellnachweis von analyten mit auf löslichen submikron-teilchen immobilisierten rezeptoren
IL80922A (en) Method and kit for heterogeneous specific binding assay using water dispersible aggregating support material
EP0461828A1 (de) Bestimmung von Analyten, die Bindungsstellen für mindestens zwei Bindungsgruppen haben
JPH03504199A (ja) 迅速な核酸検出法
GB2060690A (en) Preparation of virus sub-population having increased sensitivity toward host cells for the virus
CN101896816B (zh) 用于检测分析物的方法
US5663318A (en) Assay preparation containing capture and detection polynucleotides covalently bound to substrates with a heterobifunctional crosslinking agent
DE69032062D1 (de) Voraktivierte Proteine zur Markierung von Oligonukleotidsonden
KR900014887A (ko) 완전 세포에 적용할 수 있는 효소 분석 키트 및 방법
JPS60205367A (ja) 抗‐エプスタイン‐バールビールス抗体の酵素‐免疫螢光試験法
Ostrand-Rosenberg et al. Expression of histocompatibility-2 antigens on cultured cell lines derived from mouse blastocysts
CN105675878B (zh) 可用于诊断人肠道病毒71型感染的试剂盒及诊断方法
CN108663523A (zh) 可用于诊断人肠道病毒71型感染的试剂盒
JPH08506902A (ja) イムノアッセイ及びdnaハイブリダイゼーションアッセイにおいて使用するための水溶性ポリマー

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee