ATE178940T1 - Klonierung und sequenzierung von dermatophagoiden-antigenen (hausstaubmilben) - Google Patents
Klonierung und sequenzierung von dermatophagoiden-antigenen (hausstaubmilben)Info
- Publication number
- ATE178940T1 ATE178940T1 AT91916537T AT91916537T ATE178940T1 AT E178940 T1 ATE178940 T1 AT E178940T1 AT 91916537 T AT91916537 T AT 91916537T AT 91916537 T AT91916537 T AT 91916537T AT E178940 T1 ATE178940 T1 AT E178940T1
- Authority
- AT
- Austria
- Prior art keywords
- house dust
- allergens
- dust mites
- dermatophagoid
- antigens
- Prior art date
Links
- 241000238710 Dermatophagoides Species 0.000 title abstract 2
- 241000238711 Pyroglyphidae Species 0.000 title abstract 2
- 229940046533 house dust mites Drugs 0.000 title abstract 2
- 239000000427 antigen Substances 0.000 title 1
- 102000036639 antigens Human genes 0.000 title 1
- 108091007433 antigens Proteins 0.000 title 1
- 238000010367 cloning Methods 0.000 title 1
- 238000012163 sequencing technique Methods 0.000 title 1
- 239000013566 allergen Substances 0.000 abstract 6
- 229960004784 allergens Drugs 0.000 abstract 4
- 108090000623 proteins and genes Proteins 0.000 abstract 3
- 102000004169 proteins and genes Human genes 0.000 abstract 3
- 241000238713 Dermatophagoides farinae Species 0.000 abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 108010055622 Dermatophagoides farinae antigen f 1 Proteins 0.000 abstract 1
- 241000238740 Dermatophagoides pteronyssinus Species 0.000 abstract 1
- 108010061629 Dermatophagoides pteronyssinus antigen p 1 Proteins 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 239000000428 dust Substances 0.000 abstract 1
- 230000035945 sensitivity Effects 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
- C07K14/43513—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae
- C07K14/43531—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae from mites
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/5403—IL-3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Insects & Arthropods (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pulmonology (AREA)
- Physics & Mathematics (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US58065590A | 1990-09-11 | 1990-09-11 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE178940T1 true ATE178940T1 (de) | 1999-04-15 |
Family
ID=24321976
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT91916537T ATE178940T1 (de) | 1990-09-11 | 1991-09-10 | Klonierung und sequenzierung von dermatophagoiden-antigenen (hausstaubmilben) |
Country Status (11)
| Country | Link |
|---|---|
| US (4) | US6689876B1 (de) |
| EP (1) | EP0548200B1 (de) |
| JP (1) | JP3592709B2 (de) |
| KR (1) | KR100274321B1 (de) |
| AT (1) | ATE178940T1 (de) |
| AU (1) | AU655599B2 (de) |
| CA (1) | CA2091449C (de) |
| DE (1) | DE69131131T2 (de) |
| DK (1) | DK0548200T3 (de) |
| ES (1) | ES2133288T3 (de) |
| WO (1) | WO1992004445A1 (de) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5547669A (en) * | 1989-11-03 | 1996-08-20 | Immulogic Pharma Corp | Recombinant peptides comprising T cell epitopes of the cat allergen, Fel d I |
| US5433948A (en) * | 1990-02-13 | 1995-07-18 | Thomas; Wayne R. | Cloning and sequencing of allergens of dermatophagoides (house dust mite) |
| US7288256B1 (en) | 1991-10-16 | 2007-10-30 | Merck Patent Gmbh | T cell epitopes of the major allergens from dermatophagoides (house dust mite) |
| JPH07502890A (ja) * | 1991-10-16 | 1995-03-30 | イミユロジク・フアーマシユーチカル・コーポレーシヨン | ダーマトファゴイデス(Dermatophagoides)(家ほこりダニ)からの主要なアレルゲンのT細胞エピトープ |
| WO1994024281A1 (en) * | 1993-04-14 | 1994-10-27 | Immulogic Pharmaceutical Corporation | T cell epitopes of the major allergens from dermatophagoides (house dust mite) |
| JP4246794B2 (ja) * | 1991-10-16 | 2009-04-02 | メルク パテント ゲーエムベーハー | レコンビトープペプチド |
| AU664920B2 (en) * | 1992-08-14 | 1995-12-07 | Asahi Breweries, Ltd. | Peptide having allergenicity |
| AU7195194A (en) * | 1993-07-16 | 1995-02-13 | Meiji Milk Products Co., Ltd. | Antiallergic agent |
| JP3520089B2 (ja) * | 1993-12-22 | 2004-04-19 | アサヒビール株式会社 | 新規な組換えDerlアレルゲン物質、そのプロ体及びこれらの産生方法 |
| JPH07215996A (ja) * | 1994-01-31 | 1995-08-15 | Torii Yakuhin Kk | ダニアレルゲンのb細胞エピトープ |
| US5820862A (en) * | 1994-04-14 | 1998-10-13 | Immulogic Pharmaceutical Corporation | T cell epitopes of the major allergens from dermatophagoides (house dust mite) |
| JPH09512014A (ja) * | 1994-04-14 | 1997-12-02 | イミユロジク・フアーマシユーチカル・コーポレーシヨン | ダニアレルギー治療用の医薬ペプチド組成物 |
| SE9403526D0 (sv) | 1994-10-14 | 1994-10-14 | Astra Ab | New Peptides |
| SE9501067D0 (sv) | 1995-03-24 | 1995-03-24 | Astra Ab | New peptides |
| ES2229263T3 (es) * | 1995-03-28 | 2005-04-16 | Asahi Breweries, Ltd. | Sustancia alergena para acaridos obtenida mediante ingenieria genetica y proceso para la produccion de la misma. |
| DE69733343D1 (de) | 1996-03-21 | 2005-06-30 | Circassia Ltd | Kryptische peptide und verfahren zu ihrer identifizierung |
| ATE280183T1 (de) * | 1998-07-31 | 2004-11-15 | Asahi Chemical Ind | Anti-l7/l12-antikörper zum nachweis von bakterien |
| GB9924351D0 (en) | 1999-10-14 | 1999-12-15 | Brennan Frank | Immunomodulation methods and compositions |
| WO2001029078A2 (en) | 1999-10-15 | 2001-04-26 | Heska Corporation | Method for production and use of mite group 1 proteins |
| CN1406248A (zh) * | 2000-01-31 | 2003-03-26 | 旭化成株式会社 | 肺炎衣原体检测用抗体 |
| AU2001230532A1 (en) * | 2000-01-31 | 2001-08-14 | Asahi Kasei Kabushiki Kaisha | Antibody for detecting mycoplasma pneumoniae |
| CA2429372A1 (en) * | 2001-01-03 | 2002-08-29 | Heska Corporation | Detection of allergen-specific ige |
| FR2841906B1 (fr) * | 2002-07-05 | 2006-08-18 | Stallergenes Sa | Molecule d'acide nucleique codant une preproproteine d'allergene d'un acarien du genre dermatophagoides ou euroglyphus et son utilisation pour la production dudit allergene dans les plantes |
| WO2004019978A1 (en) * | 2002-08-29 | 2004-03-11 | National University Of Singapore | Recombinant nucleic acid useful for inducing protective immune response against allergens |
| GB0304424D0 (en) * | 2003-02-26 | 2003-04-02 | Glaxosmithkline Biolog Sa | Novel compounds |
| JP4463198B2 (ja) * | 2003-03-05 | 2010-05-12 | 財団法人化学及血清療法研究所 | 大腸菌における異種蛋白質の製造方法 |
| US20050053615A1 (en) * | 2003-07-16 | 2005-03-10 | Best Elaine A. | Variants of mite group 1 allergens for the treatment of house dust mite allergy |
| CN102516383A (zh) | 2004-04-09 | 2012-06-27 | 日本全药工业株式会社 | 新的螨变应原 |
| ES2340767T5 (es) * | 2004-07-01 | 2013-11-13 | Biomay Ag | Alérgenos de ácaros del polvo doméstico |
| US20060156851A1 (en) * | 2004-12-02 | 2006-07-20 | Jacobsen Stephen C | Mechanical serpentine device |
| CA2685308A1 (en) * | 2007-04-27 | 2009-01-29 | Dow Global Technologies Inc. | Improved production and in vivo assembly of soluble recombinant icosahedral virus-like particles |
| EA023303B1 (ru) * | 2007-08-15 | 2016-05-31 | Сиркейшиа Лимитед | Пептидная композиция для формирования толерантности к клещам домашней пыли и ее применение |
| EP2331124A1 (de) * | 2008-08-15 | 2011-06-15 | Circassia Limited | T-zell-antigen-peptid aus einem allergen zur stimulierung der il-10-produktion |
| NL2014882B1 (en) | 2015-05-29 | 2017-01-31 | Citeq B V | Allergy-specific immunotherapy compositions for use in the treatment of house-dust mite allergy. |
| WO2020046217A1 (en) * | 2018-08-28 | 2020-03-05 | Chulalongkorn University | A nucleic acid construct for inhibiting the house dust mite allergic response |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU462407B2 (en) | 1971-07-16 | 1975-06-26 | Mundepharma Ag | Mite antigen and method for manufacture |
| WO1988010297A1 (en) | 1987-06-17 | 1988-12-29 | Princess Margaret Children's Medical Research Foun | Cloning of mite allergens |
| JP2787162B2 (ja) * | 1989-08-24 | 1998-08-13 | フマキラー株式会社 | 精製ダニアレルゲン |
| JP2596466B2 (ja) * | 1990-03-03 | 1997-04-02 | アサヒビール株式会社 | ダニの主要アレルゲンの還伝情報を有するdnaおよび該アレルゲンの製造方法 |
| JP3139777B2 (ja) * | 1990-08-27 | 2001-03-05 | フマキラー株式会社 | 組換えダニアレルゲン |
| BR9813731B1 (pt) * | 1998-01-05 | 2010-08-24 | lubrificante transportador antimicrobiano compatÍvel com bebida. |
-
1991
- 1991-09-10 EP EP91916537A patent/EP0548200B1/de not_active Revoked
- 1991-09-10 DE DE69131131T patent/DE69131131T2/de not_active Revoked
- 1991-09-10 DK DK91916537T patent/DK0548200T3/da active
- 1991-09-10 JP JP51486391A patent/JP3592709B2/ja not_active Expired - Lifetime
- 1991-09-10 AU AU85062/91A patent/AU655599B2/en not_active Expired
- 1991-09-10 CA CA002091449A patent/CA2091449C/en not_active Expired - Lifetime
- 1991-09-10 WO PCT/AU1991/000417 patent/WO1992004445A1/en not_active Ceased
- 1991-09-10 AT AT91916537T patent/ATE178940T1/de not_active IP Right Cessation
- 1991-09-10 ES ES91916537T patent/ES2133288T3/es not_active Expired - Lifetime
- 1991-09-10 KR KR1019930700751A patent/KR100274321B1/ko not_active Expired - Lifetime
-
1993
- 1993-12-29 US US08/175,071 patent/US6689876B1/en not_active Expired - Lifetime
-
1995
- 1995-06-05 US US08/460,918 patent/US6060057A/en not_active Expired - Lifetime
- 1995-06-05 US US08/465,093 patent/US6086897A/en not_active Expired - Lifetime
-
2003
- 2003-12-23 US US10/746,909 patent/US20060008873A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP0548200A1 (de) | 1993-06-30 |
| DE69131131D1 (de) | 1999-05-20 |
| KR100274321B1 (ko) | 2000-12-15 |
| DE69131131T2 (de) | 1999-10-14 |
| ES2133288T3 (es) | 1999-09-16 |
| AU655599B2 (en) | 1995-01-05 |
| EP0548200A4 (de) | 1994-04-06 |
| WO1992004445A1 (en) | 1992-03-19 |
| AU8506291A (en) | 1992-03-30 |
| CA2091449A1 (en) | 1992-03-12 |
| CA2091449C (en) | 2002-11-05 |
| US6086897A (en) | 2000-07-11 |
| US6689876B1 (en) | 2004-02-10 |
| JPH06500993A (ja) | 1994-01-27 |
| KR930702523A (ko) | 1993-09-09 |
| JP3592709B2 (ja) | 2004-11-24 |
| DK0548200T3 (da) | 1999-10-25 |
| EP0548200B1 (de) | 1999-04-14 |
| US6060057A (en) | 2000-05-09 |
| US20060008873A1 (en) | 2006-01-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| RZN | Patent revoked |