NO953571L - T-celle-epitoper av vanlig raigress-pollen allergen - Google Patents

T-celle-epitoper av vanlig raigress-pollen allergen

Info

Publication number
NO953571L
NO953571L NO953571A NO953571A NO953571L NO 953571 L NO953571 L NO 953571L NO 953571 A NO953571 A NO 953571A NO 953571 A NO953571 A NO 953571A NO 953571 L NO953571 L NO 953571L
Authority
NO
Norway
Prior art keywords
loi
peptides
allergen
cell epitopes
raigress
Prior art date
Application number
NO953571A
Other languages
English (en)
Other versions
NO953571D0 (no
Inventor
Irwin J Griffith
Mei-Chang Kuo
Mohammad Luqman
Stephen Palmer Powers
Original Assignee
Immulogic Pharma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immulogic Pharma Corp filed Critical Immulogic Pharma Corp
Publication of NO953571D0 publication Critical patent/NO953571D0/no
Publication of NO953571L publication Critical patent/NO953571L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/16—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from plants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Botany (AREA)
  • Pulmonology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

oreliggende oppfinnelse tilveiebringer isolerte peptider avoi p I, et vesentlig proteinallergen av gressarten Lolium perenne. Peptider innen rammen for oppfinnelsen omfatter minst én T-celle-epitop av Loi p I, eller fortrinnsvis minst to T-celle-epitoper av et proteinallergen av Loi p I. Oppfinnelsen tilveiebringer også modifiserte peptider som har lignende, eller forbedrede, terapeutiske eller diagnostiske egenskaper som det tilsvarende naturlig forekommende allergen, eller del derav, og som i tillegg har andre egenskaper, f.eks. reduserte bivirkninger. Oppfinnelsen tilveiebringer videre nukleinsyre-sekvenser som koder for peptidene ifølge oppfinnelsen. Metoder for behandling og diagnostisering av følsomhet hos et individ overfor Loi p I eller et allergen som er immunologisk beslektet med Loi p I (som f.eks. Dac g I eller Phi p I) tilveiebringes også. Blandinger for terapeutiske eller diagnostiske anvendelser eller til bruk som reagens, omfattende ett eller flere av peptidene ifølge oppfinnelsen, tilveiebringes også.
NO953571A 1993-03-12 1995-09-11 T-celle-epitoper av vanlig raigress-pollen allergen NO953571L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3100193A 1993-03-12 1993-03-12
PCT/US1994/002537 WO1994021675A2 (en) 1993-03-12 1994-03-09 T cell epitopes of ryegrass pollen allergen

Publications (2)

Publication Number Publication Date
NO953571D0 NO953571D0 (no) 1995-09-11
NO953571L true NO953571L (no) 1995-11-10

Family

ID=21857138

Family Applications (1)

Application Number Title Priority Date Filing Date
NO953571A NO953571L (no) 1993-03-12 1995-09-11 T-celle-epitoper av vanlig raigress-pollen allergen

Country Status (10)

Country Link
EP (1) EP0688338A1 (no)
JP (1) JPH08509966A (no)
AU (1) AU684501B2 (no)
CA (1) CA2157596A1 (no)
FI (1) FI954269A7 (no)
IL (1) IL108940A0 (no)
NO (1) NO953571L (no)
NZ (1) NZ263913A (no)
WO (1) WO1994021675A2 (no)
ZA (1) ZA941708B (no)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5858689A (en) * 1993-07-22 1999-01-12 Ludwig Institute For Cancer Research Isolated peptides derived from the gage tumor rejection antigen precursor and uses thereof
SE9402089D0 (sv) * 1994-06-14 1994-06-14 Rudolf Valenta Recombinant allergen, fragments thereof, corresponding recombinant DNA molecules, vectors and hosts containing the DNA molecules, diagnostic and therapeutic uses of said allergens and fragments
EP0783322A1 (en) * 1994-09-02 1997-07-16 Immunologic Pharmaceutical Corporation Peptide compositions capable of down regulating an antigen specific immune response
US6759234B1 (en) 1994-09-02 2004-07-06 Immulogic Pharmaceutical Corporation Compositions and methods for administering to humans, peptides capable of down regulating an antigen specific immune response
US6737406B1 (en) 1996-03-21 2004-05-18 Circassia, Ltd. Cryptic peptides and method for their identification
US5817463A (en) * 1996-06-28 1998-10-06 Abbott Laboratories Nucleic acid primers and probes for detecting Mycoplasma pneumoniae
US7879977B2 (en) 1998-01-31 2011-02-01 University Of Arkansas Methods and reagents for decreasing clinical reaction to allergy
AU743647B2 (en) 1998-01-31 2002-01-31 Mt. Sinai School Of Medicine Of New York University Methods and reagents for decreasing allergic reactions
AU1951001A (en) 2000-04-06 2001-09-17 Panacea Pharm Llc Microbial delivery system
US8246945B2 (en) 2000-04-06 2012-08-21 University Of Arkansas Methods and reagents for decreasing clinical reaction to allergy
FR2809415B1 (fr) * 2000-05-29 2004-10-08 Tabacs & Allumettes Ind Clonage et sequencage de l'allergene dac g1 du pollen de dactilys glomerata, sa preparation et son utilisation
AUPR779201A0 (en) * 2001-09-20 2001-10-11 University Of Melbourne, The Immunotherapeutic and immunoprophylactic reagents
AUPS148202A0 (en) * 2002-04-02 2002-05-09 Monash University Immunotherapeutic and immunoprophylactic reagents
AU2003213861B2 (en) * 2002-04-02 2010-04-29 Circassia Limited Immunotherapeutic and immunoprophylactic reagents
GB0710529D0 (en) 2007-06-01 2007-07-11 Circassia Ltd Vaccine
NZ583362A (en) 2007-08-15 2012-06-29 Circassia Ltd Peptide with reduced dimer formation
HRP20150317T1 (hr) 2009-02-05 2015-04-24 Circassia Limited Peptidi trave za cjepivo
EP2249162A1 (en) * 2009-04-30 2010-11-10 Stallergenes Sa Method for grass species identification
WO2017004561A1 (en) 2015-07-01 2017-01-05 Alk-Abelló A/S Peptide combinations and uses thereof for treating grass allergy
US11524019B2 (en) 2017-08-21 2022-12-13 Glycom A/S Synthetic composition for reducing allergy symptoms

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1340729C (en) * 1988-03-23 1999-09-07 Mohan Bir Singh Ryegrass pollen allergen
JPH05509230A (ja) * 1990-08-17 1993-12-22 ザ・ユニバーシテイ・オブ・メルボルン ライグラスの花粉のアレルゲン
NZ243956A (en) * 1991-08-16 1997-05-26 Univ Melbourne Ryegrass pollen antigen (lol p ib), nucleic acid encoding it, host cells, vectors, monoclonal antibodies and pharmaceutical for treating ryegrass allergy

Also Published As

Publication number Publication date
EP0688338A1 (en) 1995-12-27
FI954269A0 (fi) 1995-09-12
WO1994021675A2 (en) 1994-09-29
IL108940A0 (en) 1994-06-24
JPH08509966A (ja) 1996-10-22
FI954269L (fi) 1995-09-12
AU6517594A (en) 1994-10-11
WO1994021675A3 (en) 1994-11-10
CA2157596A1 (en) 1994-09-29
ZA941708B (en) 1994-10-05
FI954269A7 (fi) 1995-09-12
AU684501B2 (en) 1997-12-18
NO953571D0 (no) 1995-09-11
NZ263913A (en) 1997-10-24

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