ATE179985T1 - Stabil solvate von avermectin verbindungen - Google Patents
Stabil solvate von avermectin verbindungenInfo
- Publication number
- ATE179985T1 ATE179985T1 AT94931307T AT94931307T ATE179985T1 AT E179985 T1 ATE179985 T1 AT E179985T1 AT 94931307 T AT94931307 T AT 94931307T AT 94931307 T AT94931307 T AT 94931307T AT E179985 T1 ATE179985 T1 AT E179985T1
- Authority
- AT
- Austria
- Prior art keywords
- avermectin compounds
- avermectin
- compounds
- disclosed
- stable solvate
- Prior art date
Links
- RRZXIRBKKLTSOM-XPNPUAGNSA-N avermectin B1a Chemical class C1=C[C@H](C)[C@@H]([C@@H](C)CC)O[C@]11O[C@H](C\C=C(C)\[C@@H](O[C@@H]2O[C@@H](C)[C@H](O[C@@H]3O[C@@H](C)[C@H](O)[C@@H](OC)C3)[C@@H](OC)C2)[C@@H](C)\C=C\C=C/2[C@]3([C@H](C(=O)O4)C=C(C)[C@@H](O)[C@H]3OC\2)O)C[C@H]4C1 RRZXIRBKKLTSOM-XPNPUAGNSA-N 0.000 title abstract 5
- 239000012453 solvate Substances 0.000 title abstract 2
- 239000005660 Abamectin Substances 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- 239000000921 anthelmintic agent Substances 0.000 abstract 1
- 229940124339 anthelmintic agent Drugs 0.000 abstract 1
- 230000002141 anti-parasite Effects 0.000 abstract 1
- 239000003096 antiparasitic agent Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 230000000749 insecticidal effect Effects 0.000 abstract 1
- 239000002917 insecticide Substances 0.000 abstract 1
- 230000007774 longterm Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000003389 potentiating effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/22—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains four or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/14—Ectoparasiticides, e.g. scabicides
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Tropical Medicine & Parasitology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- External Artificial Organs (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Separation Of Suspended Particles By Flocculating Agents (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/133,494 US5380838A (en) | 1993-10-08 | 1993-10-08 | Stable solvates of avermectin compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE179985T1 true ATE179985T1 (de) | 1999-05-15 |
Family
ID=22458871
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT94931307T ATE179985T1 (de) | 1993-10-08 | 1994-10-04 | Stabil solvate von avermectin verbindungen |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US5380838A (de) |
| EP (1) | EP0722454B1 (de) |
| JP (1) | JP2938974B2 (de) |
| AT (1) | ATE179985T1 (de) |
| AU (1) | AU681916B2 (de) |
| CA (1) | CA2171871C (de) |
| DE (1) | DE69418469T2 (de) |
| ES (1) | ES2131219T3 (de) |
| WO (1) | WO1995010525A1 (de) |
| ZA (1) | ZA947863B (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9716567D0 (en) | 1997-08-05 | 1997-10-08 | Pfizer | Process |
| KR100540046B1 (ko) | 1997-11-12 | 2006-01-10 | 미쓰비시 가가꾸 가부시키가이샤 | 퓨린유도체 및 이를 유효성분으로 함유하는 의약 |
| KR100747106B1 (ko) | 1999-05-11 | 2007-08-08 | 미쯔비시 가가꾸 가부시끼가이샤 | 퓨린 유도체 이수화물, 이를 유효성분으로 함유하는 의약및 이의 제조 중간체 |
| WO2004063147A1 (en) * | 2003-01-10 | 2004-07-29 | Novo Nordisk A/S | Salts and solvates of glucagon antagonists |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE434277B (sv) * | 1976-04-19 | 1984-07-16 | Merck & Co Inc | Sett att framstella nya antihelmintiskt verkande foreningar genom odling av streptomyces avermitilis |
| PH15982A (en) * | 1977-10-03 | 1983-05-18 | Merck & Co Inc | Selective hydrogenation producta of c-076 compounds and derivatives thereof |
| US4199569A (en) * | 1977-10-03 | 1980-04-22 | Merck & Co., Inc. | Selective hydrogenation products of C-076 compounds and derivatives thereof |
| NZ188459A (en) * | 1977-10-03 | 1982-09-07 | Merck & Co Inc | Derivatives of c-076 compounds and pesticidal compositions |
| US4206205A (en) * | 1977-10-03 | 1980-06-03 | Merck & Co., Inc. | Monosaccharide and aglycone derivatives of C-076 |
| US4171314A (en) * | 1977-12-19 | 1979-10-16 | Merck & Co., Inc. | 13-Halo and 13-deoxy C-076 compounds |
| US4734375A (en) * | 1980-05-27 | 1988-03-29 | Miles Laboratories, Inc. | Ion specific test method |
| US4457920A (en) * | 1981-09-03 | 1984-07-03 | Merck & Co., Inc. | 4a-Substituted avermectin compounds |
| US4657854A (en) * | 1983-05-05 | 1987-04-14 | Ivan Endre Modrovich | Assay systems based on magnesium-responsive enzymes |
| EP0216731B1 (de) * | 1985-09-13 | 1990-03-14 | Gesellschaft für Biotechnologische Forschung mbH (GBF) | Makrozyklische Antibiotika |
| US4812400A (en) * | 1986-07-14 | 1989-03-14 | Steinman Gary D | Process for measuring sodium levels in biological fluids |
| JPH0612999B2 (ja) * | 1986-11-17 | 1994-02-23 | 関東化学株式会社 | 塩素イオン定量用試薬 |
-
1993
- 1993-10-08 US US08/133,494 patent/US5380838A/en not_active Expired - Lifetime
-
1994
- 1994-10-04 DE DE69418469T patent/DE69418469T2/de not_active Expired - Lifetime
- 1994-10-04 AT AT94931307T patent/ATE179985T1/de not_active IP Right Cessation
- 1994-10-04 CA CA002171871A patent/CA2171871C/en not_active Expired - Lifetime
- 1994-10-04 WO PCT/US1994/011247 patent/WO1995010525A1/en not_active Ceased
- 1994-10-04 ES ES94931307T patent/ES2131219T3/es not_active Expired - Lifetime
- 1994-10-04 EP EP94931307A patent/EP0722454B1/de not_active Expired - Lifetime
- 1994-10-04 JP JP7511881A patent/JP2938974B2/ja not_active Expired - Lifetime
- 1994-10-04 AU AU80130/94A patent/AU681916B2/en not_active Expired
- 1994-10-07 ZA ZA947863A patent/ZA947863B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE69418469D1 (de) | 1999-06-17 |
| US5380838A (en) | 1995-01-10 |
| CA2171871A1 (en) | 1995-04-20 |
| WO1995010525A1 (en) | 1995-04-20 |
| ES2131219T3 (es) | 1999-07-16 |
| AU8013094A (en) | 1995-05-04 |
| EP0722454A1 (de) | 1996-07-24 |
| JP2938974B2 (ja) | 1999-08-25 |
| AU681916B2 (en) | 1997-09-11 |
| JPH09503521A (ja) | 1997-04-08 |
| CA2171871C (en) | 1999-08-03 |
| DE69418469T2 (de) | 1999-12-16 |
| EP0722454B1 (de) | 1999-05-12 |
| ZA947863B (en) | 1995-05-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |