ATE180481T1 - Verfahren zur herstellung von (-)-trans-n-p- fluorbenzoylmethyl-4-(p-fluorphenyl)-3-((3,4- (methylendioxy)phenoxy>methyl>-piperidin - Google Patents

Verfahren zur herstellung von (-)-trans-n-p- fluorbenzoylmethyl-4-(p-fluorphenyl)-3-((3,4- (methylendioxy)phenoxy>methyl>-piperidin

Info

Publication number: ATE180481T1
Authority: AT; Austria
Prior art keywords: pct; methylenedioxy; fluorophenyl; phenoxy; trans
Prior art date: 1996-02-29

Application number

AT97906144T

Other languages

English (en)

Inventor

Rafael Foguet

Santiago Gubert

Aurelio Sacristan

Jose A Ortiz

Original Assignee

Ferrer Int

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-02-29

Filing date

1997-02-28

Publication date

1999-06-15

1997-02-28 Application filed by Ferrer Int filed Critical Ferrer Int

1999-06-15 Application granted granted Critical

1999-06-15 Publication of ATE180481T1 publication Critical patent/ATE180481T1/de

Links

-1 3,4-(METHYLENEDIOXY)PHENOXY Chemical class 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1
WCYWZMWISLQXQU-UHFFFAOYSA-N methyl Chemical class [CH3] WCYWZMWISLQXQU-UHFFFAOYSA-N 0.000 title 1
ZJFWCELATJMDNO-UHFFFAOYSA-N 2-bromo-1-(4-fluorophenyl)ethanone Chemical compound FC1=CC=C(C(=O)CBr)C=C1 ZJFWCELATJMDNO-UHFFFAOYSA-N 0.000 abstract 1
UJZWJOQRSMOFMA-UHFFFAOYSA-N 2-chloro-1-(4-fluorophenyl)ethanone Chemical compound FC1=CC=C(C(=O)CCl)C=C1 UJZWJOQRSMOFMA-UHFFFAOYSA-N 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
125000000951 phenoxy group Chemical group [H]C1=C([H])C([H])=C(O*)C([H])=C1[H] 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Hydrogenated Pyridines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

AT97906144T 1996-02-29 1997-02-28 Verfahren zur herstellung von (-)-trans-n-p- fluorbenzoylmethyl-4-(p-fluorphenyl)-3-((3,4- (methylendioxy)phenoxy>methyl>-piperidin ATE180481T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
ES09600481A ES2117557B1 (es)	1996-02-29	1996-02-29	Nuevo procedimiento de obtencion de (-)-trans -n-p-fluorobenzoilmetil-4-(p-fluorofenil)-3- ((3,4-(metilendioxi)fenoxi ) metil)-piperidina.

Publications (1)

Publication Number	Publication Date
ATE180481T1 true ATE180481T1 (de)	1999-06-15

Family

ID=8293999

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT97906144T ATE180481T1 (de)	1996-02-29	1997-02-28	Verfahren zur herstellung von (-)-trans-n-p- fluorbenzoylmethyl-4-(p-fluorphenyl)-3-((3,4- (methylendioxy)phenoxy>methyl>-piperidin

Country Status (17)

Country	Link
US (1)	US5973155A (de)
EP (1)	EP0823907B1 (de)
JP (1)	JPH11504659A (de)
AT (1)	ATE180481T1 (de)
AU (1)	AU705887B2 (de)
BR (1)	BR9702123A (de)
CA (1)	CA2217171C (de)
DE (1)	DE69700236T2 (de)
DK (1)	DK0823907T3 (de)
ES (1)	ES2117557B1 (de)
GR (1)	GR3030683T3 (de)
IL (1)	IL121995A (de)
NO (1)	NO312549B1 (de)
NZ (1)	NZ328932A (de)
TW (1)	TW416941B (de)
WO (1)	WO1997031915A1 (de)
ZA (1)	ZA971074B (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SK283394B6 (sk)	1997-06-10	2003-07-01	Synthon B. V.	Zlúčeniny 4-fenylpiperidínu a jej farmaceuticky prijateľné soli, spôsob ich prípravy, liečivo s ich obsahom a ich použitie
GB9808896D0 (en) *	1998-04-25	1998-06-24	Smithkline Beecham Plc	Novel compound
CH689805A8 (fr) *	1998-07-02	2000-02-29	Smithkline Beecham Plc	Méthanesulfonate de paroxétine, procédé pour sa préparation et compositions pharmaceutiques le contenant.
EP1318988A2 (de) *	2000-09-11	2003-06-18	Sepracor, Inc.	Liganden für monoamin rezeptoren und transporter, und verwendungsmethoden dafür (neurotransmission)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3426784A1 (de) *	1984-07-20	1986-01-30	Bosch Gmbh Robert	Magnetoresistiver sensor zur abgabe von elektrischen signalen
DK231088D0 (da) *	1988-04-28	1988-04-28	Ferrosan As	Piperidinforbindelser, deres fremstilling og anvendelse
ES2102295B1 (es) *	1994-03-18	1998-04-01	Ferrer Int	Nuevos compuestos derivados de la n-benzoilmetil-piperidina.
GB2297550B (en) *	1995-02-06	1997-04-09	Smithkline Beecham Plc	Paroxetine hydrochloride anhydrate substantially free of bound organic solvent
CN1068597C (zh) *	1995-05-17	2001-07-18	诺沃挪第克公司	制备4－芳基－哌啶衍生物的方法

1996
- 1996-02-29 ES ES09600481A patent/ES2117557B1/es not_active Expired - Fee Related
1997
- 1997-01-31 TW TW086101103A patent/TW416941B/zh active
- 1997-02-10 ZA ZA9701074A patent/ZA971074B/xx unknown
- 1997-02-28 DE DE69700236T patent/DE69700236T2/de not_active Expired - Fee Related
- 1997-02-28 DK DK97906144T patent/DK0823907T3/da active
- 1997-02-28 IL IL12199597A patent/IL121995A/xx not_active IP Right Cessation
- 1997-02-28 WO PCT/EP1997/001007 patent/WO1997031915A1/en not_active Ceased
- 1997-02-28 BR BR9702123-7A patent/BR9702123A/pt not_active Application Discontinuation
- 1997-02-28 NZ NZ328932A patent/NZ328932A/en unknown
- 1997-02-28 AU AU20940/97A patent/AU705887B2/en not_active Ceased
- 1997-02-28 AT AT97906144T patent/ATE180481T1/de not_active IP Right Cessation
- 1997-02-28 EP EP97906144A patent/EP0823907B1/de not_active Expired - Lifetime
- 1997-02-28 JP JP9530630A patent/JPH11504659A/ja not_active Ceased
- 1997-02-28 CA CA002217171A patent/CA2217171C/en not_active Expired - Fee Related
- 1997-02-28 US US08/945,442 patent/US5973155A/en not_active Expired - Fee Related
- 1997-10-27 NO NO19974958A patent/NO312549B1/no unknown
1999
- 1999-07-05 GR GR990401765T patent/GR3030683T3/el unknown

Also Published As

Publication number	Publication date
ES2117557B1 (es)	1999-07-01
CA2217171A1 (en)	1997-09-04
ZA971074B (en)	1997-11-18
DE69700236T2 (de)	1999-09-30
EP0823907A1 (de)	1998-02-18
EP0823907B1 (de)	1999-05-26
CA2217171C (en)	2001-09-11
JPH11504659A (ja)	1999-04-27
AU2094097A (en)	1997-09-16
ES2117557A1 (es)	1998-08-01
US5973155A (en)	1999-10-26
NO974958L (no)	1997-10-27
TW416941B (en)	2001-01-01
WO1997031915A1 (en)	1997-09-04
IL121995A (en)	2001-01-28
NO312549B1 (no)	2002-05-27
NZ328932A (en)	1998-04-27
IL121995A0 (en)	1998-03-10
AU705887B2 (en)	1999-06-03
DE69700236D1 (de)	1999-07-01
DK0823907T3 (da)	1999-11-08
BR9702123A (pt)	1999-12-28
NO974958D0 (no)	1997-10-27
GR3030683T3 (en)	1999-11-30

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Legal Events

Date	Code	Title	Description
1999-12-15	UEP	Publication of translation of european patent specification
2006-11-15	REN	Ceased due to non-payment of the annual fee