ATE180493T1 - Rezeptor für 6(r)-l-erythro-5,6,7,8- tetrahydrobiopterin - Google Patents
Rezeptor für 6(r)-l-erythro-5,6,7,8- tetrahydrobiopterinInfo
- Publication number
- ATE180493T1 ATE180493T1 AT92923528T AT92923528T ATE180493T1 AT E180493 T1 ATE180493 T1 AT E180493T1 AT 92923528 T AT92923528 T AT 92923528T AT 92923528 T AT92923528 T AT 92923528T AT E180493 T1 ATE180493 T1 AT E180493T1
- Authority
- AT
- Austria
- Prior art keywords
- binding
- tetrahydrobiopterin
- erythro
- receptor
- capacity
- Prior art date
Links
- FNKQXYHWGSIFBK-RPDRRWSUSA-N sapropterin Chemical compound N1=C(N)NC(=O)C2=C1NC[C@H]([C@@H](O)[C@@H](O)C)N2 FNKQXYHWGSIFBK-RPDRRWSUSA-N 0.000 abstract 3
- UMCMPZBLKLEWAF-BCTGSCMUSA-N 3-[(3-cholamidopropyl)dimethylammonio]propane-1-sulfonate Chemical compound C([C@H]1C[C@H]2O)[C@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@@H](CCC(=O)NCCC[N+](C)(C)CCCS([O-])(=O)=O)C)[C@@]2(C)[C@@H](O)C1 UMCMPZBLKLEWAF-BCTGSCMUSA-N 0.000 abstract 2
- 239000012528 membrane Substances 0.000 abstract 2
- 206010003805 Autism Diseases 0.000 abstract 1
- 208000020706 Autistic disease Diseases 0.000 abstract 1
- 102000014914 Carrier Proteins Human genes 0.000 abstract 1
- 206010029333 Neurosis Diseases 0.000 abstract 1
- YZCKVEUIGOORGS-NJFSPNSNSA-N Tritium Chemical compound [3H] YZCKVEUIGOORGS-NJFSPNSNSA-N 0.000 abstract 1
- 102000004142 Trypsin Human genes 0.000 abstract 1
- 108090000631 Trypsin Proteins 0.000 abstract 1
- 210000001557 animal structure Anatomy 0.000 abstract 1
- 108091008324 binding proteins Proteins 0.000 abstract 1
- 210000000172 cytosol Anatomy 0.000 abstract 1
- 239000002808 molecular sieve Substances 0.000 abstract 1
- 208000015238 neurotic disease Diseases 0.000 abstract 1
- URGAHOPLAPQHLN-UHFFFAOYSA-N sodium aluminosilicate Chemical compound [Na+].[Al+3].[O-][Si]([O-])=O.[O-][Si]([O-])=O URGAHOPLAPQHLN-UHFFFAOYSA-N 0.000 abstract 1
- 229910052722 tritium Inorganic materials 0.000 abstract 1
- 239000012588 trypsin Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Toxicology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cell Biology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Enzymes And Modification Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP30089491 | 1991-11-16 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE180493T1 true ATE180493T1 (de) | 1999-06-15 |
Family
ID=17890406
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT92923528T ATE180493T1 (de) | 1991-11-16 | 1992-11-16 | Rezeptor für 6(r)-l-erythro-5,6,7,8- tetrahydrobiopterin |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US5606020A (de) |
| EP (1) | EP0592673B1 (de) |
| AT (1) | ATE180493T1 (de) |
| DE (1) | DE69229270D1 (de) |
| WO (1) | WO1993010155A1 (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE218345T1 (de) * | 1994-08-05 | 2002-06-15 | Suntory Ltd | Arzneimittel gegen spinocerebellare degeneration |
| PL3138566T3 (pl) | 2003-11-17 | 2022-03-07 | Biomarin Pharmaceutical Inc. | Leczenie fenyloketonurii z użyciem bh4 |
| AU2005259961B2 (en) * | 2004-06-25 | 2012-05-17 | Board Of Regents, The University Of Texas System | Methods and compositions for the treatment of attention deficit hyperactivity disorder and hyperphenylalanemia |
| EP2436379A1 (de) * | 2004-11-17 | 2012-04-04 | BioMarin Pharmaceutical Inc. | Stabile Tablettenformulierung |
| US9216178B2 (en) | 2011-11-02 | 2015-12-22 | Biomarin Pharmaceutical Inc. | Dry blend formulation of tetrahydrobiopterin |
-
1992
- 1992-11-16 AT AT92923528T patent/ATE180493T1/de active
- 1992-11-16 DE DE69229270T patent/DE69229270D1/de not_active Expired - Lifetime
- 1992-11-16 EP EP92923528A patent/EP0592673B1/de not_active Expired - Lifetime
- 1992-11-16 WO PCT/JP1992/001496 patent/WO1993010155A1/ja not_active Ceased
- 1992-11-16 US US08/087,802 patent/US5606020A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP0592673A4 (de) | 1994-04-27 |
| EP0592673B1 (de) | 1999-05-26 |
| AU668117B2 (en) | 1996-04-26 |
| US5606020A (en) | 1997-02-25 |
| WO1993010155A1 (fr) | 1993-05-27 |
| DE69229270D1 (en) | 1999-07-01 |
| AU2930892A (en) | 1993-06-15 |
| EP0592673A1 (de) | 1994-04-20 |
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