ATE181076T1 - Gehinderte ester von rapamycin und ihre verwendung als arzneimittel - Google Patents

Gehinderte ester von rapamycin und ihre verwendung als arzneimittel

Info

Publication number
ATE181076T1
ATE181076T1 AT95903559T AT95903559T ATE181076T1 AT E181076 T1 ATE181076 T1 AT E181076T1 AT 95903559 T AT95903559 T AT 95903559T AT 95903559 T AT95903559 T AT 95903559T AT E181076 T1 ATE181076 T1 AT E181076T1
Authority
AT
Austria
Prior art keywords
rapamycin
medicinal products
hindered esters
arylalkyl
alkyl
Prior art date
Application number
AT95903559T
Other languages
English (en)
Inventor
Frances Christy Nelson
Guy Alan Schiehser
Original Assignee
American Home Prod
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Home Prod filed Critical American Home Prod
Application granted granted Critical
Publication of ATE181076T1 publication Critical patent/ATE181076T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/18—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Transplantation (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT95903559T 1993-11-22 1994-11-18 Gehinderte ester von rapamycin und ihre verwendung als arzneimittel ATE181076T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/156,206 US5385908A (en) 1993-11-22 1993-11-22 Hindered esters of rapamycin

Publications (1)

Publication Number Publication Date
ATE181076T1 true ATE181076T1 (de) 1999-06-15

Family

ID=22558566

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95903559T ATE181076T1 (de) 1993-11-22 1994-11-18 Gehinderte ester von rapamycin und ihre verwendung als arzneimittel

Country Status (13)

Country Link
US (1) US5385908A (de)
EP (1) EP0730598B1 (de)
JP (1) JP3710140B2 (de)
AT (1) ATE181076T1 (de)
AU (1) AU1257595A (de)
CA (1) CA2176955A1 (de)
DE (1) DE69419032T2 (de)
DK (1) DK0730598T3 (de)
ES (1) ES2133715T3 (de)
GR (1) GR3031018T3 (de)
SG (1) SG80525A1 (de)
TW (1) TW342391B (de)
WO (1) WO1995014696A1 (de)

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AU1257595A (en) 1995-06-13
US5385908A (en) 1995-01-31
EP0730598A1 (de) 1996-09-11
SG80525A1 (en) 2001-05-22
JP3710140B2 (ja) 2005-10-26
TW342391B (en) 1998-10-11
GR3031018T3 (en) 1999-12-31
JPH09505592A (ja) 1997-06-03
DE69419032T2 (de) 1999-10-07
DE69419032D1 (de) 1999-07-15
CA2176955A1 (en) 1995-06-01
HK1013063A1 (en) 1999-08-13
DK0730598T3 (da) 1999-11-15
EP0730598B1 (de) 1999-06-09
ES2133715T3 (es) 1999-09-16

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