ATE181327T1 - Indolderivate - Google Patents

Indolderivate

Info

Publication number: ATE181327T1
Authority: AT; Austria
Prior art keywords: pct; hydrogen; date; indole derivatives; pyridyl
Prior art date: 1990-10-20

Application number

AT91919221T

Other languages

English (en)

Inventor

Christopher Chapleo

Gay Patricia Fagan

Original Assignee

Reckitt & Colmann Prod Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-10-20

Filing date

1991-10-10

Publication date

1999-07-15

1991-10-10 Application filed by Reckitt & Colmann Prod Ltd filed Critical Reckitt & Colmann Prod Ltd

1999-07-15 Application granted granted Critical

1999-07-15 Publication of ATE181327T1 publication Critical patent/ATE181327T1/de

Links

SIKJAQJRHWYJAI-UHFFFAOYSA-N Indole Chemical class C1=CC=C2NC=CC2=C1 SIKJAQJRHWYJAI-UHFFFAOYSA-N 0.000 title 1
229940054051 antipsychotic indole derivative Drugs 0.000 title 1
229910052739 hydrogen Inorganic materials 0.000 abstract 4
239000001257 hydrogen Substances 0.000 abstract 4
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 4
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 2
125000004105 2-pyridyl group Chemical group N1=C([*])C([H])=C([H])C([H])=C1[H] 0.000 abstract 1
125000003349 3-pyridyl group Chemical group N1=C([H])C([*])=C([H])C([H])=C1[H] 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
206010012601 diabetes mellitus Diseases 0.000 abstract 1
231100000252 nontoxic Toxicity 0.000 abstract 1
230000003000 nontoxic effect Effects 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Diabetes (AREA)
General Chemical & Material Sciences (AREA)
Emergency Medicine (AREA)
Hematology (AREA)
Obesity (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
Endocrinology (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Indole Compounds (AREA)

AT91919221T 1990-10-20 1991-10-10 Indolderivate ATE181327T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB909022858A GB9022858D0 (en)	1990-10-20	1990-10-20	Derivatives of indoles

Publications (1)

Publication Number	Publication Date
ATE181327T1 true ATE181327T1 (de)	1999-07-15

Family

ID=10684077

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT91919221T ATE181327T1 (de)	1990-10-20	1991-10-10	Indolderivate

Country Status (14)

Country	Link
US (1)	US5385919A (de)
EP (1)	EP0553218B1 (de)
JP (1)	JPH06501945A (de)
AT (1)	ATE181327T1 (de)
AU (1)	AU648351B2 (de)
CA (1)	CA2094383A1 (de)
DE (1)	DE69131353T2 (de)
GB (1)	GB9022858D0 (de)
IE (1)	IE63139B1 (de)
IL (1)	IL99777A0 (de)
NZ (1)	NZ240120A (de)
PT (1)	PT99280B (de)
WO (1)	WO1992006972A1 (de)
ZA (1)	ZA918083B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1266897A3 (de) *	1997-12-19	2003-12-03	Eli Lilly And Company	Hypoglykämische Imidazolinderivate
AU2201699A (en) *	1997-12-19	1999-07-12	Eli Lilly And Company	Hypoglycemic imidazoline compounds
US6410562B1 (en)	1998-12-18	2002-06-25	Eli Lilly And Company	Hypoglycemic imidazoline compounds
JP2007527925A (ja) *	2005-01-14	2007-10-04	テバファーマシューティカルインダストリーズリミティド	粗カンデサルタンシレキセチルの調製
WO2013189905A1 (en)	2012-06-20	2013-12-27	F. Hoffmann-La Roche Ag	Pyrrolopyrazone inhibitors of tankyrase

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2751393A (en) *	1953-05-13	1956-06-19		Imidazoline derivatives of aryl indoles
US4328345A (en) *	1978-10-02	1982-05-04	Schering Corporation	Pyridyl substituted indoles
US4436746A (en) *	1982-09-30	1984-03-13	Ciba-Geigy Corporation	Thromboxane synthetase inhibitory N-substituted-2-(1-imidazolyl)indoles
DE3465993D1 (en) *	1983-08-11	1987-10-15	Synthelabo	Indole derivatives, their preparation and their therapeutical application
US5017584A (en) *	1984-12-20	1991-05-21	Sterling Drug Inc.	Antidepressant 2-(4,5-dihydro-1H-imidazolyl)-dihydro-1H-indoles, -1,2,3,4-tetrahydroquinolines and -1H-indoles, and methods of use thereas
DE3677277D1 (de) *	1985-02-08	1991-03-07	Synthelabo	(dihydro-4,5-1h-imidazolyl-2)-2-dihydro-2,3-indolderivate, ihre herstellung und anwendung als heilmittel.
US4912125A (en) *	1985-09-03	1990-03-27	Ciba-Geigy Corporation	2,3-dihydro-2-(4,5-dihydroimidazol-2-yl)-indoles for reducing intraocular pressure
US4908376A (en) *	1985-09-03	1990-03-13	Ciba-Geigy Corporation	2,3-dihydro-2-(4,5-dihydroimidazol-2-yl)-indoles in composition form for reducing intraocular pressure
DE3824658A1 (de) *	1988-07-15	1990-01-18	Schering Ag	N-hetaryl-imidazolderivate
JP2722586B2 (ja) *	1989-01-13	1998-03-04	大正製薬株式会社	インドリルイミダゾール誘導体
PT95899A (pt) *	1989-11-17	1991-09-13	Glaxo Group Ltd	Processo para a preparacao de derivados indole

1990
- 1990-10-20 GB GB909022858A patent/GB9022858D0/en active Pending
1991
- 1991-09-26 IE IE339391A patent/IE63139B1/en not_active IP Right Cessation
- 1991-10-07 NZ NZ240120A patent/NZ240120A/en unknown
- 1991-10-09 ZA ZA918083A patent/ZA918083B/xx unknown
- 1991-10-10 EP EP91919221A patent/EP0553218B1/de not_active Expired - Lifetime
- 1991-10-10 AU AU86681/91A patent/AU648351B2/en not_active Ceased
- 1991-10-10 CA CA002094383A patent/CA2094383A1/en not_active Abandoned
- 1991-10-10 WO PCT/GB1991/001756 patent/WO1992006972A1/en not_active Ceased
- 1991-10-10 DE DE69131353T patent/DE69131353T2/de not_active Expired - Fee Related
- 1991-10-10 JP JP3516463A patent/JPH06501945A/ja active Pending
- 1991-10-10 AT AT91919221T patent/ATE181327T1/de not_active IP Right Cessation
- 1991-10-10 US US08/039,232 patent/US5385919A/en not_active Expired - Fee Related
- 1991-10-17 IL IL99777A patent/IL99777A0/xx unknown
- 1991-10-18 PT PT99280A patent/PT99280B/pt not_active IP Right Cessation

Also Published As

Publication number	Publication date
JPH06501945A (ja)	1994-03-03
ZA918083B (en)	1992-12-30
AU648351B2 (en)	1994-04-21
CA2094383A1 (en)	1992-04-21
DE69131353D1 (de)	1999-07-22
NZ240120A (en)	1993-10-26
IE63139B1 (en)	1995-03-22
PT99280B (pt)	1999-04-30
IE913393A1 (en)	1992-04-22
AU8668191A (en)	1992-05-20
EP0553218B1 (de)	1999-06-16
WO1992006972A1 (en)	1992-04-30
GB9022858D0 (en)	1990-12-05
EP0553218A1 (de)	1993-08-04
DE69131353T2 (de)	1999-10-14
US5385919A (en)	1995-01-31
IL99777A0 (en)	1992-08-18
PT99280A (pt)	1992-08-31

Legal Events

Date	Code	Title	Description
1999-12-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
DK0696281T3 (da)	1999-11-01	Hidtil ukendte 5-pyrrolyl-2-pyridylmethylsulfinylbenzimidazolderivater
DK0944617T3 (da)	2003-09-01	Krystaller af benzimidazolderivater og deres fremstilling
FI943948A0 (fi)	1994-08-26	Heterosykliset hiilihappojohdannaiset
DE69620443D1 (de)	2002-05-08	Naphthyl substituierte benzimidazolderivate als antikoagulantien
BR1100086A (pt)	2000-07-25	Derivados de fluoralcóxibenzilamino de heterocìclos contendo nitrogênio
BR9405910A (pt)	1995-12-26	Piridinas substituídas heterocíclicas herbicidas
DE69433984D1 (de)	2004-10-14	Arylpiperazinderivate von indol als liganden der rezeptoren 5 ht1-like, 5 ht1b und 5 ht1d
HUT60464A (en)	1992-09-28	Process for producing n-phenylbenzamide derivatives and pharmaceutical compositions comprising such compounds as active ingredient
ATE148108T1 (de)	1997-02-15	Beta,beta-dimethyl-4-piperidinethanamin-derivat als inhibitoren der cholesterin-biosynthese
ATE191478T1 (de)	2000-04-15	3,6-disubstituierte-2-fluoropyridine
DE69227258D1 (de)	1998-11-12	Neue Endothelin-Antagonisten und ihre Herstellung
NO179865C (no)	1997-01-02	Nytt -fenylisoserinderivat og dets fremstilling
ATE220397T1 (de)	2002-07-15	Substituierte biphenyloxazoline
DE69131353D1 (de)	1999-07-22	Indolderivate
ATE72438T1 (de)	1992-02-15	2-pyridyl-penem-verbindungen.
DE59304311D1 (de)	1996-11-28	N-substituierte 3-azabicyclo[3.2.0]heptan-derivate als neuroleptika
DK0788491T3 (da)	2000-05-08	6-Polyfluoralkoxy- og 6-polyfluoralkyl-2-aminobenzothiazol-derivater
NZ236186A (en)	1993-09-27	Pyrrolidine and piperidine derivatives and pharmaceutical compositions
NO944332L (no)	1994-11-14	Substituerte pyridiner, samt fremstilling og farmasöytisk anvendelse derav
DK0516729T3 (da)	1994-04-25	N-Phenyl-N-alkoxycarbonylalkylglycinamider, deres fremstilling og lægemidler indeholdende disse forbindelser
PT98389A (pt)	1992-05-29	Processo de preparacao de derivados de estreptogramina