ATE181501T1 - Verwendung von l-deprenyl zur hemmung des alterniedergangs des immunsystems in säugetieren - Google Patents

Verwendung von l-deprenyl zur hemmung des alterniedergangs des immunsystems in säugetieren

Info

Publication number
ATE181501T1
ATE181501T1 AT96103701T AT96103701T ATE181501T1 AT E181501 T1 ATE181501 T1 AT E181501T1 AT 96103701 T AT96103701 T AT 96103701T AT 96103701 T AT96103701 T AT 96103701T AT E181501 T1 ATE181501 T1 AT E181501T1
Authority
AT
Austria
Prior art keywords
deprenyl
mammals
immune system
inhibit aging
aging decline
Prior art date
Application number
AT96103701T
Other languages
English (en)
Inventor
Norton W Milgram
David R Stevens
Gwendolyn O Ivy
Original Assignee
Deprenyl Animal Health Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27076843&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE181501(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US07/576,011 external-priority patent/US5151449A/en
Application filed by Deprenyl Animal Health Inc filed Critical Deprenyl Animal Health Inc
Application granted granted Critical
Publication of ATE181501T1 publication Critical patent/ATE181501T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
    • A61P5/12—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH for decreasing, blocking or antagonising the activity of the posterior pituitary hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Reproductive Health (AREA)
  • Obesity (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Thin Film Transistor (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pulse Circuits (AREA)
  • Electrotherapy Devices (AREA)
  • Rotary Switch, Piano Key Switch, And Lever Switch (AREA)
AT96103701T 1990-08-31 1991-03-28 Verwendung von l-deprenyl zur hemmung des alterniedergangs des immunsystems in säugetieren ATE181501T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/576,011 US5151449A (en) 1990-08-31 1990-08-31 Use of L-deprenyl for retention of specific physiological functions
US64345291A 1991-01-18 1991-01-18

Publications (1)

Publication Number Publication Date
ATE181501T1 true ATE181501T1 (de) 1999-07-15

Family

ID=27076843

Family Applications (2)

Application Number Title Priority Date Filing Date
AT96103701T ATE181501T1 (de) 1990-08-31 1991-03-28 Verwendung von l-deprenyl zur hemmung des alterniedergangs des immunsystems in säugetieren
AT91302820T ATE149350T1 (de) 1990-08-31 1991-03-28 Verwendung des l-deprenyls zur verzögerung der altersbedingten zerstörung des gedächtnis bei hunden

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT91302820T ATE149350T1 (de) 1990-08-31 1991-03-28 Verwendung des l-deprenyls zur verzögerung der altersbedingten zerstörung des gedächtnis bei hunden

Country Status (15)

Country Link
US (2) US5276057A (de)
EP (2) EP0473252B1 (de)
JP (3) JP2819072B2 (de)
AT (2) ATE181501T1 (de)
AU (1) AU633714B2 (de)
BR (1) BR9103506A (de)
CA (1) CA2039194C (de)
DE (2) DE69131386T2 (de)
DK (2) DK0473252T3 (de)
ES (2) ES2097790T3 (de)
GR (2) GR3022971T3 (de)
ID (1) ID19492A (de)
MX (1) MX9100067A (de)
MY (2) MY124210A (de)
NZ (1) NZ238277A (de)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5565495A (en) * 1990-08-31 1996-10-15 Deprenyl Animal Health, Inc. Method for survival curve shifting in dogs
CA2039194C (en) * 1990-08-31 1997-01-28 Norton W. Milgram Uses of l-deprenyl and compositions for same
US5561163A (en) * 1990-08-31 1996-10-01 Deprenyl Animal Health, Inc. Treating hearing loss with deprenyl
US5444095A (en) * 1991-04-04 1995-08-22 University Of Toronto, Innovations Foundation Use of deprenyl to rescue damaged nerve cells
US5844003A (en) * 1991-04-04 1998-12-01 Innovations Foundation Use of deprenyl compounds to maintain, prevent loss, or recover nerve cell function
WO1992017169A1 (en) * 1991-04-04 1992-10-15 The University Of Toronto Innovations Foundation Use of deprenyl to maintain, prevent loss, or recover nerve cell function
US5767164A (en) * 1991-04-04 1998-06-16 Innovations Foundation Use of deprenyl to rescue damaged nerve cells
US5242950A (en) * 1992-04-23 1993-09-07 Somerset Pharmaceuticals, Inc. Treatment of macular degeneration
US5817336A (en) * 1993-04-02 1998-10-06 Orion-Yhtyma Oy Composition containing selegiline
EP0623344B1 (de) * 1993-05-04 2000-07-26 Ceva Sante Animale Anwendung von Selegilin in Tiermedizin
FR2704756B1 (fr) * 1993-05-04 1995-07-28 Sanofi Elf Utilisation de la sélégiline en médecine vétérinaire.
HU223475B1 (hu) * 1994-10-24 2004-07-28 Chinoin Gyógyszer és Vegyészeti Termékek Gyára Rt. Selegilint tartalmazó liposzoma-készítmény és eljárás ennek előállítására
US6033682A (en) 1995-01-13 2000-03-07 Somerset Pharmaceuticals, Inc. S(+) desmethylselegiline and its use in therapeutic methods and pharmaceutical compositions
JP3036847B2 (ja) 1995-01-13 2000-04-24 サマーセット・ファーマシューティカルズ・インコーポレイテッド デスメチルセレギリンを用いる方法および医薬組成物
AU723047B2 (en) * 1995-02-10 2000-08-17 University Of Toronto Innovations Foundation, The Deprenyl compounds for treatment of glaucoma
US6316022B1 (en) 1995-06-07 2001-11-13 Noven Pharmaceuticals, Inc. Transdermal compositions containing low molecular weight drugs which are liquid at room temperatures
JPH11506744A (ja) * 1995-06-07 1999-06-15 ノウブン ファーマシューティカルズ インク． 室温で液体である低分子量薬を含む経皮組成物
CN1207675A (zh) * 1995-11-06 1999-02-10 萨默塞特药品有限公司 丙炔苯丙胺的经颊和舌下给药法
ES2178405T3 (es) * 1998-03-16 2002-12-16 Somerset Pharmaceuticals Inc Uso de selegilina o de desmetilselegilina para tratar heridas, quemaduras y lesiones cutaneas.
US20030212144A1 (en) * 2001-07-18 2003-11-13 Mohankumar Sheba J.J. Method for inducing an estrous cycle and pregnancy in a female mammal
JP4757024B2 (ja) * 2002-11-07 2011-08-24 テクニオン リサーチ アンド ディベラップメント ファウンデイション リミテッド 神経保護鉄キレート剤及びそれを含む医薬組成物
CA2523567A1 (en) * 2003-04-25 2004-11-11 Indevus Pharmaceuticals, Inc. Method for promoting uninterrupted sleep by administration of trospium chloride
EP1686973A4 (de) 2003-11-25 2009-03-25 Technion Res & Dev Foundation Zusammensetzungen und verfahren zur behandlung von kardiovaskulären erkrankungen und krankheiten
US8097608B2 (en) * 2003-11-25 2012-01-17 Technion Research And Development Foundation Ltd. Methods for treatment of cardiovascular disorders and diseases
JP2005232148A (ja) * 2004-02-03 2005-09-02 Technion Research & Development Foundation Ltd 神経保護剤としてプロパルギルアミンの使用
FR2884421B1 (fr) 2005-04-15 2007-08-10 Virbac Sa Nouveaux moyens de regulation des troubles du comportement chez les animaux de compagnie
US8263655B2 (en) 2005-10-06 2012-09-11 Technion Research And Development Foundation Ltd Methods for treatment of renal failure
WO2011082080A1 (en) * 2009-12-29 2011-07-07 Hill's Pet Nutrition, Inc. Compositions including pyruvate for companion animals and methods of use thereof
EP2531181B1 (de) 2010-02-03 2019-04-10 Pharma Two B Ltd. Retard-formulierungen von rasagilin und ihre verwendung
CN103860503A (zh) * 2012-12-10 2014-06-18 天津市汉康医药生物技术有限公司 一种治疗帕金森病的缓释药物组合物及其制备方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA871155A (en) * 1971-05-18 Chinoin Gyogyszer-Es Vegyeszeti Termekek Gyara Rt Optically active phenyl isopropylamine derivatives having pharmaceutical properties and their preparation
HU187775B (en) * 1982-07-14 1986-02-28 Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt,Hu New process for producing propargile-amines of pharmaceutical activity
US4916151A (en) * 1985-12-05 1990-04-10 Merrell Dow Pharmaceuticals Inc. Method of treating parkinson's syndrome
US4871550A (en) * 1986-09-05 1989-10-03 Millman Phillip L Nutrient composition for athletes and method of making and using the same
US4880883A (en) * 1987-06-03 1989-11-14 Wisconsin Alumni Research Foundation Biocompatible polyurethanes modified with lower alkyl sulfonate and lower alkyl carboxylate
US4861800A (en) * 1987-08-18 1989-08-29 Buyske Donald A Method for administering the drug deprenyl so as to minimize the danger of side effects
HU208484B (en) * 1988-08-17 1993-11-29 Chinoin Gyogyszer Es Vegyeszet Process for producing pharmaceutical composition containing acid additional salt of selegilin as active component for treating schisofrenia
US5192808A (en) * 1990-08-31 1993-03-09 Deprenyl Animal Health, Inc. Therapeutic effect of L-deprenyl in the management of pituitary-dependent hyperadrenocorticism (cushing's disease)
CA2039194C (en) * 1990-08-31 1997-01-28 Norton W. Milgram Uses of l-deprenyl and compositions for same

Also Published As

Publication number Publication date
MY110217A (en) 1998-03-31
JPH09328422A (ja) 1997-12-22
EP0473252A3 (en) 1992-08-05
MX9100067A (es) 1992-04-01
JP2884500B2 (ja) 1999-04-19
ES2097790T3 (es) 1997-04-16
ATE149350T1 (de) 1997-03-15
EP0473252B1 (de) 1997-03-05
DK0473252T3 (da) 1997-09-15
DE69124875T2 (de) 1997-06-26
DE69131386D1 (de) 1999-07-29
US5276057A (en) 1994-01-04
EP0732101A1 (de) 1996-09-18
CA2039194A1 (en) 1992-03-01
EP0732101B1 (de) 1999-06-23
BR9103506A (pt) 1992-05-12
JPH09328423A (ja) 1997-12-22
DE69131386T2 (de) 1999-11-25
JP2819072B2 (ja) 1998-10-30
JP2884501B2 (ja) 1999-04-19
GR3031263T3 (en) 1999-12-31
GR3022971T3 (en) 1997-06-30
ID19492A (id) 1998-07-16
DE69124875D1 (de) 1997-04-10
AU7395791A (en) 1992-03-05
CA2039194C (en) 1997-01-28
DK0732101T3 (da) 1999-11-22
JPH04230624A (ja) 1992-08-19
HK1011611A1 (en) 1999-07-16
US5387615A (en) 1995-02-07
ES2135123T3 (es) 1999-10-16
AU633714B2 (en) 1993-02-04
MY124210A (en) 2006-06-30
NZ238277A (en) 1993-10-26
EP0473252A2 (de) 1992-03-04

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Legal Events

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UEP Publication of translation of european patent specification
RZN Patent revoked