ATE182085T1 - Verfahren zur trennung eines materials von einer mischung durch verdrängungschromatographie - Google Patents
Verfahren zur trennung eines materials von einer mischung durch verdrängungschromatographieInfo
- Publication number
- ATE182085T1 ATE182085T1 AT95911901T AT95911901T ATE182085T1 AT E182085 T1 ATE182085 T1 AT E182085T1 AT 95911901 T AT95911901 T AT 95911901T AT 95911901 T AT95911901 T AT 95911901T AT E182085 T1 ATE182085 T1 AT E182085T1
- Authority
- AT
- Austria
- Prior art keywords
- column
- known material
- mixture
- materials
- passing
- Prior art date
Links
- 239000000463 material Substances 0.000 title abstract 11
- 239000000203 mixture Substances 0.000 title abstract 4
- 238000002086 displacement chromatography Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 230000005526 G1 to G0 transition Effects 0.000 abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- 238000006073 displacement reaction Methods 0.000 abstract 2
- 238000012856 packing Methods 0.000 abstract 2
- 239000007788 liquid Substances 0.000 abstract 1
- 239000002244 precipitate Substances 0.000 abstract 1
- 238000000926 separation method Methods 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/42—Selective adsorption, e.g. chromatography characterised by the development mode, e.g. by displacement or by elution
- B01D15/422—Displacement mode
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J39/00—Cation exchange; Use of material as cation exchangers; Treatment of material for improving the cation exchange properties
- B01J39/26—Cation exchangers for chromatographic processes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
Landscapes
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/223,165 US5427686A (en) | 1994-04-05 | 1994-04-05 | Process for separating material from mixture using displacement chromatography |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE182085T1 true ATE182085T1 (de) | 1999-07-15 |
Family
ID=22835333
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT95911901T ATE182085T1 (de) | 1994-04-05 | 1995-02-23 | Verfahren zur trennung eines materials von einer mischung durch verdrängungschromatographie |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US5427686A (de) |
| EP (1) | EP0754083B1 (de) |
| JP (1) | JPH10501885A (de) |
| AT (1) | ATE182085T1 (de) |
| CA (1) | CA2187090A1 (de) |
| DE (1) | DE69510780T2 (de) |
| WO (1) | WO1995026795A1 (de) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5851400A (en) * | 1997-03-21 | 1998-12-22 | University Of Maryland At Baltimore County | Method for eliminating the displacer in displacement chromatography of proteins |
| US6239262B1 (en) | 1998-01-07 | 2001-05-29 | Rensselaer Polytechnic Institute | Low molecular weight displacers for protein purification in hydrophobic interaction and reversed phase chromatographic systems |
| SI20072A (sl) * | 1998-09-18 | 2000-04-30 | LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d. | Postopek za pridobivanje inhibitorjev HMG-CoA reduktaze |
| US7141602B2 (en) * | 1998-09-18 | 2006-11-28 | Lek Pharmaceuticals D.D. | Process for obtaining HMG-CoA reductase inhibitors of high purity |
| US6746695B1 (en) | 1998-10-02 | 2004-06-08 | Armadillo Pharmaceuticals, Inc. | Pharmaceutical preparations of bioactive substances extracted from natural sources |
| GB9822963D0 (en) * | 1998-10-20 | 1998-12-16 | Agner Erik | Improvements in or relating to chromatography |
| US6573373B1 (en) | 1999-06-29 | 2003-06-03 | Isis Pharmaceuticals, Inc. | High affinity, low molecular weight displacers for oligonucleotide purification |
| US6610125B2 (en) | 2001-10-23 | 2003-08-26 | University Of Maine System Board Of Trustees | Selective filtration and concentration of toxic nerve agents |
| US6929747B2 (en) * | 2002-02-28 | 2005-08-16 | Renesselaer Polytechnic Institute | High-affinity, low-molecular-mass displacers for ion-exchange chromatography |
| DE112006001012B4 (de) * | 2005-04-22 | 2017-05-18 | Waters Technologies Corp. (N.D.Ges.D. Staates Delaware) | Verfahren für eine auf Massenspektrometrie gerichtete Aufbereitung von Biopolymeren |
| WO2009135656A1 (en) * | 2008-05-06 | 2009-11-12 | Lonza Biologics Plc. | A method for the purification of antibodies using displacement chromatography |
| GB201115218D0 (en) * | 2011-09-02 | 2011-10-19 | Glaxo Group Ltd | Novel process |
| CN105727912B (zh) * | 2016-04-07 | 2018-08-17 | 湖北省农业科学院农业质量标准与检测技术研究所 | 一种新型胆固醇键合硅胶固定相及其制备方法和应用 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3925019A (en) * | 1973-08-06 | 1975-12-09 | Dow Chemical Co | Chromatographic analysis of ionic species |
| US3920398A (en) * | 1973-08-06 | 1975-11-18 | Dow Chemical Co | Method for chromatographic analysis of organic acids or their carboxylate salts |
| US3971842A (en) * | 1974-08-08 | 1976-07-27 | Atlantic Richfield Company | Continuous displacement chromatographic separation |
| US4274967A (en) * | 1978-07-07 | 1981-06-23 | Technicon Instruments Corporation | Chromatographic apparatus and method |
| AU536948B2 (en) * | 1979-12-19 | 1984-05-31 | Asahi Kasei Kogyo Kabushiki Kaisha | Separation of rare earth metals |
| JPS59145022A (ja) * | 1983-02-08 | 1984-08-20 | Japan Atom Energy Res Inst | リチウム同位体を分離する方法 |
| JPS6075530A (ja) * | 1983-09-30 | 1985-04-27 | Asahi Chem Ind Co Ltd | 金属元素の新しい分離精製方法 |
| US4724081A (en) * | 1986-04-28 | 1988-02-09 | Soken Kagaku Kabushiki Kaisha | Process and apparatus for separation by liquid chromatography |
| GB2223692A (en) * | 1988-09-16 | 1990-04-18 | Philips Nv | Liquid chromatography |
| US5028696A (en) * | 1988-10-28 | 1991-07-02 | Torres Anthony R | Ion exchange and separation method |
| US4915843A (en) * | 1988-11-28 | 1990-04-10 | Union Oil Company Of California | Continuous displacement chromatographic method |
-
1994
- 1994-04-05 US US08/223,165 patent/US5427686A/en not_active Expired - Fee Related
-
1995
- 1995-02-23 EP EP95911901A patent/EP0754083B1/de not_active Expired - Lifetime
- 1995-02-23 AT AT95911901T patent/ATE182085T1/de active
- 1995-02-23 JP JP7525678A patent/JPH10501885A/ja active Pending
- 1995-02-23 DE DE69510780T patent/DE69510780T2/de not_active Expired - Fee Related
- 1995-02-23 WO PCT/US1995/002288 patent/WO1995026795A1/en not_active Ceased
- 1995-02-23 CA CA002187090A patent/CA2187090A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US5427686A (en) | 1995-06-27 |
| DE69510780D1 (de) | 1999-08-19 |
| DE69510780T2 (de) | 2000-01-13 |
| WO1995026795A1 (en) | 1995-10-12 |
| CA2187090A1 (en) | 1995-10-12 |
| JPH10501885A (ja) | 1998-02-17 |
| EP0754083A1 (de) | 1997-01-22 |
| EP0754083B1 (de) | 1999-07-14 |
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