ATE182888T1 - Tocopherolderivate - Google Patents

Tocopherolderivate

Info

Publication number: ATE182888T1
Authority: AT; Austria
Prior art keywords: amino acid; compound; thiol group; bonding via; tocopherol derivative
Prior art date: 1994-05-20

Application number

AT95107593T

Other languages

English (en)

Inventor

Kazumi Ogata

Hidetoshi Nakao

Original Assignee

Senju Pharma Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-05-20

Filing date

1995-05-18

Publication date

1999-08-15

1995-05-18 Application filed by Senju Pharma Co filed Critical Senju Pharma Co

1999-08-15 Application granted granted Critical

1999-08-15 Publication of ATE182888T1 publication Critical patent/ATE182888T1/de

Links

150000003611 tocopherol derivatives Chemical class 0.000 title abstract 3
150000001875 compounds Chemical class 0.000 abstract 2
229940079593 drug Drugs 0.000 abstract 2
239000003814 drug Substances 0.000 abstract 2
RWSXRVCMGQZWBV-WDSKDSINSA-N glutathione Chemical compound OC(=O)[C@@H](N)CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O RWSXRVCMGQZWBV-WDSKDSINSA-N 0.000 abstract 2
125000003396 thiol group Chemical group [H]S* 0.000 abstract 2
108010024636 Glutathione Proteins 0.000 abstract 1
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
XUJNEKJLAYXESH-REOHCLBHSA-N L-Cysteine Chemical compound SC[C@H](N)C(O)=O XUJNEKJLAYXESH-REOHCLBHSA-N 0.000 abstract 1
239000006096 absorbing agent Substances 0.000 abstract 1
150000001370 alpha-amino acid derivatives Chemical class 0.000 abstract 1
235000008206 alpha-amino acids Nutrition 0.000 abstract 1
230000001437 anti-cataract Effects 0.000 abstract 1
230000002490 cerebral effect Effects 0.000 abstract 1
239000008406 cosmetic ingredient Substances 0.000 abstract 1
235000018417 cysteine Nutrition 0.000 abstract 1
XUJNEKJLAYXESH-UHFFFAOYSA-N cysteine Natural products SCC(N)C(O)=O XUJNEKJLAYXESH-UHFFFAOYSA-N 0.000 abstract 1
229960003180 glutathione Drugs 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
239000004615 ingredient Substances 0.000 abstract 1
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
239000003381 stabilizer Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
- C07D311/70—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with two hydrocarbon radicals attached in position 2 and elements other than carbon and hydrogen in position 6
- C07D311/72—3,4-Dihydro derivatives having in position 2 at least one methyl radical and in position 6 one oxygen atom, e.g. tocopherols

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Pyrane Compounds (AREA)
Cosmetics (AREA)
Plural Heterocyclic Compounds (AREA)

AT95107593T 1994-05-20 1995-05-18 Tocopherolderivate ATE182888T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP10648494		1994-05-20

Publications (1)

Publication Number	Publication Date
ATE182888T1 true ATE182888T1 (de)	1999-08-15

Family

ID=14434754

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT95107593T ATE182888T1 (de)	1994-05-20	1995-05-18	Tocopherolderivate

Country Status (8)

Country	Link
US (1)	US5606080A (de)
EP (1)	EP0683164B1 (de)
KR (1)	KR950032165A (de)
AT (1)	ATE182888T1 (de)
CA (1)	CA2148148A1 (de)
DE (1)	DE69511163T2 (de)
ES (1)	ES2134376T3 (de)
TW (1)	TW288014B (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
KR100195291B1 (ko) *	1997-07-12	1999-06-15	서경배	비이온성 비타민
CA2315679A1 (en) *	1997-12-24	1999-07-08	Senju Pharmaceutical Co., Ltd.	Vitamin e derivatives
KR20000000840A (ko) *	1998-06-03	2000-01-15	김영대	신규한 폴리옥시프로필렌폴리옥시에틸렌 비타민 e 및 그의제조방법
US6426362B1 (en)	1999-10-08	2002-07-30	Galileo Laboratories, Inc.	Formulations of tocopherols and methods of making and using them
US7034054B2 (en) *	2000-12-15	2006-04-25	Galileo Pharmaceuticals, Inc.	Methods for the prevention and treatment of cerebral ischemia using non-alpha tocopherols
KR100453727B1 (ko) *	2001-01-30	2004-10-20	김영대	신규한 폴리옥시프로필렌폴리옥시에틸렌 비타민 ｅ 및그의 제조방법
KR100438402B1 (ko) *	2001-05-30	2004-07-02	김영대	폴리옥시프로필렌-폴리옥시에틸렌 비타민 이를 이용한저점도 수중유형 유화 화장료
AU2002352726A1 (en)	2001-11-15	2003-06-10	Galileo Laboratories, Inc.	Formulations and methods for treatment or amelioration of inflammatory conditions
US6858227B1 (en)	2001-11-21	2005-02-22	Sonus Pharmaceuticals, Inc.	Vitamin E conjugates
KR100488220B1 (ko) *	2002-05-21	2005-05-06	김영대	폴리옥시프로필렌-폴리옥시에틸렌(ｐｏｐ-ｐｏｅ) 비타민ｅ를 함유한 나노에말션 화장료 조성물 및 그의 제조방법
WO2005042539A1 (en) *	2003-10-29	2005-05-12	Sonus Pharmaceuticals, Inc.	Tocopherol-modified therapeutic drug compounds
US20080045559A1 (en) *	2003-10-29	2008-02-21	Sonus Pharmaceuticals, Inc.	Tocopherol-modified therapeutic drug compounds
US7790701B2 (en)	2006-04-19	2010-09-07	Gelest Technologies, Inc.	Silicon-based tocopherol derivatives
WO2011153353A1 (en)	2010-06-02	2011-12-08	The Board Of Trustees For The University Of Arkansas	Tocopherol derivatives and methods of use
MX379061B (es)	2013-09-13	2025-03-04	Bioventures Llc	Preparacion y uso de una composicion para la prevencion y mitigacion de los efectos de la radiacion.
US20160324914A1 (en)	2015-05-05	2016-11-10	Tocol Pharmaceuticals, Llc	Use of rice bran oil distillate extract for prevention and mitigation of the effects of radiation

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CH529746A (de) *	1968-08-01	1972-10-31	Spofa Vereinigte Pharma Werke	Verfahren zur Herstellung von Chromanderivaten
JPS57175186A (en) *	1981-04-20	1982-10-28	Fujimoto Seiyaku Kk	Novel vitamin e derivative and its preparation

1995
- 1995-04-28 CA CA002148148A patent/CA2148148A1/en not_active Abandoned
- 1995-05-03 TW TW084104418A patent/TW288014B/zh active
- 1995-05-11 US US08/438,971 patent/US5606080A/en not_active Expired - Fee Related
- 1995-05-17 KR KR1019950012327A patent/KR950032165A/ko not_active Withdrawn
- 1995-05-18 ES ES95107593T patent/ES2134376T3/es not_active Expired - Lifetime
- 1995-05-18 DE DE69511163T patent/DE69511163T2/de not_active Expired - Fee Related
- 1995-05-18 EP EP95107593A patent/EP0683164B1/de not_active Expired - Lifetime
- 1995-05-18 AT AT95107593T patent/ATE182888T1/de active

Also Published As

Publication number	Publication date
EP0683164B1 (de)	1999-08-04
DE69511163D1 (de)	1999-09-09
KR950032165A (ko)	1995-12-20
DE69511163T2 (de)	1999-11-25
TW288014B (de)	1996-10-11
EP0683164A1 (de)	1995-11-22
CA2148148A1 (en)	1995-11-21
US5606080A (en)	1997-02-25
ES2134376T3 (es)	1999-10-01

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