ATE183081T1 - Doxorubicine enkapsulierende liposomen - Google Patents
Doxorubicine enkapsulierende liposomenInfo
- Publication number
- ATE183081T1 ATE183081T1 AT94500197T AT94500197T ATE183081T1 AT E183081 T1 ATE183081 T1 AT E183081T1 AT 94500197 T AT94500197 T AT 94500197T AT 94500197 T AT94500197 T AT 94500197T AT E183081 T1 ATE183081 T1 AT E183081T1
- Authority
- AT
- Austria
- Prior art keywords
- doxorubicine
- encapsulating liposomes
- liposomes
- encapsulating
- cf3ch2o
- Prior art date
Links
- AOJJSUZBOXZQNB-TZSSRYMLSA-N Doxorubicin Chemical compound O([C@H]1C[C@@](O)(CC=2C(O)=C3C(=O)C=4C=CC=C(C=4C(=O)C3=C(O)C=21)OC)C(=O)CO)[C@H]1C[C@H](N)[C@H](O)[C@H](C)O1 AOJJSUZBOXZQNB-TZSSRYMLSA-N 0.000 title abstract 4
- 239000002502 liposome Substances 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229960004679 doxorubicin Drugs 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000001990 intravenous administration Methods 0.000 abstract 1
- 230000001012 protector Effects 0.000 abstract 1
- 230000001988 toxicity Effects 0.000 abstract 1
- 231100000419 toxicity Toxicity 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Dispersion Chemistry (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES09302481A ES2072223B1 (es) | 1993-11-25 | 1993-11-25 | Liposomas encapsulando doxorubicina. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE183081T1 true ATE183081T1 (de) | 1999-08-15 |
Family
ID=8283745
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT94500197T ATE183081T1 (de) | 1993-11-25 | 1994-11-25 | Doxorubicine enkapsulierende liposomen |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US5605703A (de) |
| EP (1) | EP0655239B1 (de) |
| JP (1) | JP4256930B2 (de) |
| AT (1) | ATE183081T1 (de) |
| DE (1) | DE69420012T2 (de) |
| DK (1) | DK0655239T3 (de) |
| ES (1) | ES2072223B1 (de) |
| WO (1) | WO1995014459A1 (de) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2154560B1 (es) * | 1998-09-16 | 2001-12-01 | Lipotec Sa | Composicion a base de derivados de cromanos y su uso para reducir quimicamente las reacciones oxidativas o inducidas por radicales libres. |
| IT1315253B1 (it) * | 1999-10-22 | 2003-02-03 | Novuspharma Spa | Preparazione liposomiale di 6,9-bis-(2-amminoetil)ammino|benzog|isochinolin-5,10-dione dimaleato |
| FR2808189B1 (fr) | 2000-04-28 | 2004-03-05 | Oreal | Lipochroman-6 comme inhibiteur de no-synthase et utilisations |
| ES2186484B1 (es) | 2000-10-10 | 2004-07-01 | Lipotec, S.A. | Liposomas encapsulando farmacos anticancerosos y uso de los mismos en el tratamiento de tumores malignos. |
| US7029695B2 (en) * | 2001-07-10 | 2006-04-18 | Telik, Inc. | Therapeutic compositions containing glutathione analogs |
| EP1463487B1 (de) * | 2001-12-19 | 2010-05-19 | Research Development Foundation | Liposomale abgabe von verbindungen auf vitamin-e-basis |
| US20030236301A1 (en) * | 2001-12-19 | 2003-12-25 | Bob Sanders | Liposomal delivery of vitamin E based compounds |
| US20050058698A1 (en) * | 2002-01-21 | 2005-03-17 | Nolan Yvonne Mairead | Pharmaceutically acceptable phosphate-glycerol carrying bodies and uses relating to Parkinson's Disease |
| CA2368656A1 (en) * | 2002-01-21 | 2003-07-21 | Vasogen Ireland Limited | Receptor-ligand pairing for anti-inflammatory response |
| DE10259014A1 (de) | 2002-12-16 | 2004-06-24 | Henkel Kgaa | Antioxidans-Kombinationen mit6,7-disubstituierten 2,2-Dialkylchromanen oder-chromenen |
| US20050009772A1 (en) * | 2003-05-06 | 2005-01-13 | The Regents Of The University Of California | Methods and compositions for the treatment of glaucoma and other retinal diseases |
| CA2574802A1 (en) | 2004-07-20 | 2006-02-02 | Isogenis, Inc. | Specific inhibition of autoimmunity and diseases associated with autoantigens |
| US7470672B2 (en) * | 2006-07-31 | 2008-12-30 | Savvipharm Inc. | Compositions and methods of reducing tissue levels of drugs when given as orotate derivatives |
| US7750018B2 (en) * | 2006-12-06 | 2010-07-06 | Tactical Therapeutics, Inc | Use of carboxiamidotriazole (CAI) orotate in macular degeneration |
| DE102006062501A1 (de) | 2006-12-28 | 2008-07-03 | Henkel Kgaa | Kosmetische und dermatologische Öl-in-Wasser-Emulsionen mit selbstkonservierenden Eigenschaften |
| ES2310142B1 (es) * | 2007-06-15 | 2009-12-04 | Lipotec S.A | Compuestos reguladores de la pigmentacion. |
| WO2010127271A1 (en) | 2009-04-30 | 2010-11-04 | Intezyne Technologies, Incorporated | Polymer micelles containing anthracylines for the treatment of cancer |
| US8524784B2 (en) | 2009-04-30 | 2013-09-03 | Intezyne Technologies, Incorporated | Polymer micelles containing anthracylines for the treatment of cancer |
| DE102009026414A1 (de) | 2009-05-22 | 2010-11-25 | Henkel Ag & Co. Kgaa | Hautbehandlung zur Porenverfeinerung |
| US20130195962A1 (en) * | 2010-04-28 | 2013-08-01 | National University Corporation Hokkaido University | Lipid membrane structure |
| CN103083239B (zh) | 2012-12-26 | 2015-11-25 | 中国人民解放军第四军医大学 | 一种蟾毒灵脂质体及其制备方法和应用 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0153955A1 (de) * | 1983-09-06 | 1985-09-11 | Health Research, Inc. | Verfahren zum verabreichen von liposomen zum herabsetzen der toxizität eines antitumor-arzneimittels |
| US4797285A (en) * | 1985-12-06 | 1989-01-10 | Yissum Research And Development Company Of The Hebrew University Of Jerusalem | Lipsome/anthraquinone drug composition and method |
| AU7128887A (en) * | 1986-02-10 | 1987-08-25 | Liposome Technology, Inc. | Controlled-release liposome delivery system |
| US4927571A (en) * | 1987-05-18 | 1990-05-22 | Liposome Technology, Inc. | Preparation of injectable doxorubicin/liposome suspension |
| DE4000397A1 (de) * | 1990-01-09 | 1991-07-11 | Hoechst Ag | Lipidselektive antioxidantien sowie deren herstellung und verwendung |
| WO1992002208A1 (en) * | 1990-08-08 | 1992-02-20 | Liposome Technology, Inc. | Stable doxorubicin/liposome composition |
| CA2055990A1 (en) * | 1990-11-22 | 1992-05-23 | David G. Schena | Phospholipid-vitamin derivatives and methods for preparation thereof |
-
1993
- 1993-11-25 ES ES09302481A patent/ES2072223B1/es not_active Expired - Fee Related
-
1994
- 1994-11-23 US US08/346,236 patent/US5605703A/en not_active Expired - Lifetime
- 1994-11-25 AT AT94500197T patent/ATE183081T1/de active
- 1994-11-25 DE DE69420012T patent/DE69420012T2/de not_active Expired - Lifetime
- 1994-11-25 WO PCT/ES1994/000127 patent/WO1995014459A1/es not_active Ceased
- 1994-11-25 DK DK94500197T patent/DK0655239T3/da active
- 1994-11-25 EP EP94500197A patent/EP0655239B1/de not_active Expired - Lifetime
- 1994-11-25 JP JP51485695A patent/JP4256930B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP0655239A1 (de) | 1995-05-31 |
| EP0655239B1 (de) | 1999-08-11 |
| WO1995014459A1 (es) | 1995-06-01 |
| DE69420012D1 (de) | 1999-09-16 |
| US5605703A (en) | 1997-02-25 |
| JP4256930B2 (ja) | 2009-04-22 |
| JPH08506124A (ja) | 1996-07-02 |
| DK0655239T3 (da) | 2000-03-20 |
| DE69420012T2 (de) | 2000-03-23 |
| ES2072223A1 (es) | 1995-07-01 |
| ES2072223B1 (es) | 1996-03-16 |
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