ATE183190T1 - Erythromycinderivate, ihr verfahren zur herstellung und ihre verwendung als arzneimittel - Google Patents

Erythromycinderivate, ihr verfahren zur herstellung und ihre verwendung als arzneimittel

Info

Publication number: ATE183190T1
Authority: AT; Austria
Prior art keywords: image; production; medicinal products; erythromycin derivatives; radical
Prior art date: 1993-03-09

Application number

AT94400491T

Other languages

English (en)

Inventor

Constantin Agouridas

Yannick Benedetti

Jean-Francois Chantot

Alexis Denis

Original Assignee

Hoechst Marion Roussel Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-03-09

Filing date

1994-03-08

Publication date

1999-08-15

1994-03-08 Application filed by Hoechst Marion Roussel Inc filed Critical Hoechst Marion Roussel Inc

1999-08-15 Application granted granted Critical

1999-08-15 Publication of ATE183190T1 publication Critical patent/ATE183190T1/de

Links

ULGZDMOVFRHVEP-RWJQBGPGSA-N Erythromycin Chemical class O([C@@H]1[C@@H](C)C(=O)O[C@@H]([C@@]([C@H](O)[C@@H](C)C(=O)[C@H](C)C[C@@](C)(O)[C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C)(C)O)CC)[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1 ULGZDMOVFRHVEP-RWJQBGPGSA-N 0.000 title 1
229940126601 medicinal product Drugs 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 2
-1 CO2R5 Proteins 0.000 abstract 1
101100295741 Gallus gallus COR4 gene Proteins 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
125000003342 alkenyl group Chemical group 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
125000000304 alkynyl group Chemical group 0.000 abstract 1
125000003118 aryl group Chemical group 0.000 abstract 1
230000003115 biocidal effect Effects 0.000 abstract 1
125000001072 heteroaryl group Chemical group 0.000 abstract 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Engineering & Computer Science (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
Genetics & Genomics (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Chemical Kinetics & Catalysis (AREA)
Epidemiology (AREA)
Saccharide Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

AT94400491T 1993-03-09 1994-03-08 Erythromycinderivate, ihr verfahren zur herstellung und ihre verwendung als arzneimittel ATE183190T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR9302674A FR2702480B1 (fr)	1993-03-09	1993-03-09	Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.

Publications (1)

Publication Number	Publication Date
ATE183190T1 true ATE183190T1 (de)	1999-08-15

Family

ID=9444766

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT94400491T ATE183190T1 (de)	1993-03-09	1994-03-08	Erythromycinderivate, ihr verfahren zur herstellung und ihre verwendung als arzneimittel

Country Status (23)

Country	Link
US (1)	US5439889A (de)
EP (1)	EP0614905B1 (de)
JP (1)	JP3228835B2 (de)
KR (1)	KR100285972B1 (de)
CN (1)	CN1040877C (de)
AT (1)	ATE183190T1 (de)
AU (1)	AU671708B2 (de)
BR (1)	BR9400847A (de)
CA (1)	CA2118564C (de)
DE (1)	DE69419950T2 (de)
DK (1)	DK0614905T3 (de)
ES (1)	ES2135546T3 (de)
FI (1)	FI110513B (de)
FR (1)	FR2702480B1 (de)
GR (1)	GR3031330T3 (de)
HU (1)	HU219354B (de)
IL (1)	IL108622A (de)
MA (1)	MA23129A1 (de)
OA (1)	OA09892A (de)
RU (1)	RU2126803C1 (de)
TW (1)	TW353661B (de)
UA (1)	UA41871C2 (de)
ZA (1)	ZA941610B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5527780A (en) *	1992-11-05	1996-06-18	Roussel Uclaf	Erythromycin derivatives
FR2718450B1 (fr) *	1994-04-08	1997-01-10	Roussel Uclaf	Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.
GB9513756D0 (en) *	1995-07-06	1995-09-06	Smithkline Beecham Plc	Novel process & compounds
ATE296831T1 (de) *	1996-09-04	2005-06-15	Abbott Lab	6-0-substituierte ketoliden mit antibakteriellen wirkung
FR2760017B1 (fr) *	1997-02-27	1999-04-30	Hoechst Marion Roussel Inc	Nouveaux derives de l'erytromycine, leur procede de preparation et leur application comme medicaments
CZ20011512A3 (cs) *	1998-11-03	2001-09-12	Pfizer Products Inc.	Nová makrolidová antibiotika
TR200103395T2 (tr) *	1999-05-24	2002-04-22	Pfizer Products Inc.	13-metil eritromisin türevleri.
US6573409B1 (en)	1999-07-02	2003-06-03	The Nutrasweet Company	Process for the preparation of 3,3-dimethylbutanal
WO2005007143A2 (en) *	2003-07-14	2005-01-27	The Board Of Trustees Of The University Of Illinois	Use of makrolides and ketolides for the treatment of tuberculosis

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR487411A (fr) *	1916-03-06	1918-07-03	Henri Dreyfus	Procédé pour la fabrication de l'aldéhyde acétique en partant de l'acétylène
FR2534588B2 (fr) *	1982-10-15	1985-09-20	Roussel Uclaf	Nouvelles oximes derivees de l'erythromycine, leur procede de preparation et leur application comme medicaments
EP0201166B1 (de) *	1985-03-12	1990-02-07	Beecham Group Plc	Erythromycin-Derivate
PT86800B (pt) *	1987-02-24	1992-05-29	Beecham Group Plc	Processo para a preparacao de derivados de eritromicina
GB8729369D0 (en) *	1987-12-16	1988-01-27	Beecham Group Plc	Chemical compounds
IL99995A (en) *	1990-11-21	1997-11-20	Roussel Uclaf	Erythromycin derivatives, their preparation and pharmaceutical compositions containing them
US5912331A (en) *	1991-03-15	1999-06-15	Merck & Co., Inc.	Process for the preparation of 9-deoxo-9(Z)-hydroxyiminoerythromycin A
JPH089652B2 (ja) *	1991-04-03	1996-01-31	竹本油脂株式会社	ラジカル硬化性液状混合物、及びこれを含有するラジカル硬化性組成物、並びにこれらを硬化して得られる成形物

1993
- 1993-03-09 FR FR9302674A patent/FR2702480B1/fr not_active Expired - Lifetime
1994
- 1994-02-11 IL IL10862294A patent/IL108622A/en not_active IP Right Cessation
- 1994-03-07 US US08/207,355 patent/US5439889A/en not_active Expired - Lifetime
- 1994-03-08 DE DE69419950T patent/DE69419950T2/de not_active Expired - Lifetime
- 1994-03-08 KR KR1019940004433A patent/KR100285972B1/ko not_active Expired - Lifetime
- 1994-03-08 ZA ZA941610A patent/ZA941610B/xx unknown
- 1994-03-08 CA CA002118564A patent/CA2118564C/fr not_active Expired - Lifetime
- 1994-03-08 DK DK94400491T patent/DK0614905T3/da active
- 1994-03-08 ES ES94400491T patent/ES2135546T3/es not_active Expired - Lifetime
- 1994-03-08 AT AT94400491T patent/ATE183190T1/de active
- 1994-03-08 CN CN94102533A patent/CN1040877C/zh not_active Expired - Lifetime
- 1994-03-08 HU HU9400679A patent/HU219354B/hu unknown
- 1994-03-08 FI FI941094A patent/FI110513B/fi not_active IP Right Cessation
- 1994-03-08 EP EP94400491A patent/EP0614905B1/de not_active Expired - Lifetime
- 1994-03-09 RU RU94007342A patent/RU2126803C1/ru active
- 1994-03-09 UA UA94005117A patent/UA41871C2/uk unknown
- 1994-03-09 AU AU57639/94A patent/AU671708B2/en not_active Expired
- 1994-03-09 MA MA23436A patent/MA23129A1/fr unknown
- 1994-03-09 JP JP06441694A patent/JP3228835B2/ja not_active Expired - Lifetime
- 1994-03-09 OA OA60480A patent/OA09892A/fr unknown
- 1994-03-09 BR BR9400847A patent/BR9400847A/pt not_active Application Discontinuation
- 1994-04-01 TW TW083102896A patent/TW353661B/zh not_active IP Right Cessation
1999
- 1999-09-24 GR GR990402432T patent/GR3031330T3/el unknown

Also Published As

Publication number	Publication date
DE69419950D1 (de)	1999-09-16
FR2702480B1 (fr)	1995-04-28
IL108622A0 (en)	1994-05-30
ES2135546T3 (es)	1999-11-01
CA2118564A1 (fr)	1994-09-10
CN1040877C (zh)	1998-11-25
HU9400679D0 (en)	1994-06-28
AU5763994A (en)	1994-09-15
DE69419950T2 (de)	2000-01-13
EP0614905B1 (de)	1999-08-11
KR100285972B1 (ko)	2001-05-02
EP0614905A1 (de)	1994-09-14
UA41871C2 (uk)	2001-10-15
US5439889A (en)	1995-08-08
JPH06321942A (ja)	1994-11-22
AU671708B2 (en)	1996-09-05
FI941094L (fi)	1994-09-10
GR3031330T3 (en)	1999-12-31
RU2126803C1 (ru)	1999-02-27
HUT71472A (en)	1995-11-28
FR2702480A1 (fr)	1994-09-16
HU219354B (en)	2001-03-28
FI110513B (fi)	2003-02-14
CN1108259A (zh)	1995-09-13
CA2118564C (fr)	2007-05-08
FI941094A0 (fi)	1994-03-08
IL108622A (en)	1999-08-17
DK0614905T3 (da)	2000-03-06
JP3228835B2 (ja)	2001-11-12
BR9400847A (pt)	1994-11-01
TW353661B (en)	1999-03-01
OA09892A (fr)	1994-09-15
MA23129A1 (fr)	1994-10-01
ZA941610B (en)	1995-03-24
KR940021571A (ko)	1994-10-19

Legal Events

Date	Code	Title	Description
2000-01-15	UEP	Publication of translation of european patent specification
2005-05-15	EEIH	Change in the person of patent owner

Publication	Publication Date	Title
DE69301897D1 (de)	1996-04-25	Erythromycinderivate, ihr Verfahren zur Herstellung und ihre Verwendung als Arzneimitteln
BG100951A (en)	1997-08-29	Novel erythromycin derivatives, method for their preparation and their use as drugs
DE69416306D1 (de)	1999-03-11	Sphingoglycolipid und verwendung davon
ATE133165T1 (de)	1996-02-15	Aza-macrozyklen und verfahren zu deren herstellung
HUP9902576A1 (hu)	1999-12-28	Új eritromicinszármazékok, eljárás előállításukra és alkalmazásuk gyógyászati készítményekben
ATE132145T1 (de)	1996-01-15	Verfahren zur herstellung von bacchatin iii und von desacetyl-10-bacchatin iii derivate
FI933903A0 (fi)	1993-09-07	Substituerade cyklohexanderivat, foerfarande foer framstaellning daerav och anvaendning av foereningar foer behandling av sjukdomar
ATE183190T1 (de)	1999-08-15	Erythromycinderivate, ihr verfahren zur herstellung und ihre verwendung als arzneimittel
ATE155140T1 (de)	1997-07-15	3-deoxyoligosacchariden, verfahren zur ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen
DE59105459D1 (de)	1995-06-14	9-HALOGEN-11(Beta)-HYDROXY-PROSTAGLANDINDERIVATE, VERFAHREN ZU IHRER HERSTELLUNG UND IHRE VERWENDUNG ALS ARZNEIMITTEL.
YU25699A (sh)	2002-06-19	Novi derivati eritromicina, postupak za njihovu izradu i njihova primena
DE69711920D1 (de)	2002-05-16	Neue histidinderivate, verfahren zu ihrer herstellung und ihre verwendung als mittel gegen freie radikale
HUT71797A (en)	1996-02-28	Cyclohexane derivatives, process for producing them and their use for the treatment of disease
ATE170520T1 (de)	1998-09-15	Eburnan-derivate, verfahren zur ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen
AU6694290A (en)	1991-05-30	Synthesis of perfluoroalkyl bromides
AU1234488A (en)	1988-09-01	New 2-(2,3-dihydro-2-oxo-3-benzofuranyl) acetic acid derivatives, processes for preparing them and the pharmaceutical compositions which contain them
AU6823490A (en)	1991-06-27	New substituted amino acid derivatives, process for preparing these and pharmaceutical compositions containing them
ATE53839T1 (de)	1990-06-15	2,3-dihydro-3-phenyl-benzofuran-2-onacetamidderivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel.
DE69904940D1 (de)	2003-02-20	6-deoxy-erythromycin-derivate, ihrer herstellung, und ihrer verwendung als arzneimitteln
ATE181331T1 (de)	1999-07-15	Salmycine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel