ZA941610B - Derivatives of erythromycin their preparation process and their use as medicaments - Google Patents

Derivatives of erythromycin their preparation process and their use as medicaments

Info

Publication number: ZA941610B
Authority: ZA; South Africa
Prior art keywords: image; erythromycin; medicaments; derivatives; preparation process
Prior art date: 1993-03-09

Application number

ZA941610A

Other languages

English (en)

Inventor

Constantin Agouridas

Yannick Benedetti

Jean-Francois Chantot

Alexis Denis

Original Assignee

Roussel Uclaf

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-03-09

Filing date

1994-03-08

Publication date

1995-03-24

1994-03-08 Application filed by Roussel Uclaf filed Critical Roussel Uclaf

1995-03-24 Publication of ZA941610B publication Critical patent/ZA941610B/xx

Links

ULGZDMOVFRHVEP-RWJQBGPGSA-N Erythromycin Chemical class O([C@@H]1[C@@H](C)C(=O)O[C@@H]([C@@]([C@H](O)[C@@H](C)C(=O)[C@H](C)C[C@@](C)(O)[C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C)(C)O)CC)[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1 ULGZDMOVFRHVEP-RWJQBGPGSA-N 0.000 title 1
239000003814 drug Substances 0.000 title 1
238000002360 preparation method Methods 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 2
-1 CO2R5 Proteins 0.000 abstract 1
101100295741 Gallus gallus COR4 gene Proteins 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
125000003342 alkenyl group Chemical group 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
125000000304 alkynyl group Chemical group 0.000 abstract 1
125000003118 aryl group Chemical group 0.000 abstract 1
230000003115 biocidal effect Effects 0.000 abstract 1
125000001072 heteroaryl group Chemical group 0.000 abstract 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Engineering & Computer Science (AREA)
Biotechnology (AREA)
Biochemistry (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Epidemiology (AREA)
Saccharide Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

ZA941610A 1993-03-09 1994-03-08 Derivatives of erythromycin their preparation process and their use as medicaments ZA941610B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR9302674A FR2702480B1 (fr)	1993-03-09	1993-03-09	Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.

Publications (1)

Publication Number	Publication Date
ZA941610B true ZA941610B (en)	1995-03-24

Family

ID=9444766

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA941610A ZA941610B (en)	1993-03-09	1994-03-08	Derivatives of erythromycin their preparation process and their use as medicaments

Country Status (23)

Country	Link
US (1)	US5439889A (de)
EP (1)	EP0614905B1 (de)
JP (1)	JP3228835B2 (de)
KR (1)	KR100285972B1 (de)
CN (1)	CN1040877C (de)
AT (1)	ATE183190T1 (de)
AU (1)	AU671708B2 (de)
BR (1)	BR9400847A (de)
CA (1)	CA2118564C (de)
DE (1)	DE69419950T2 (de)
DK (1)	DK0614905T3 (de)
ES (1)	ES2135546T3 (de)
FI (1)	FI110513B (de)
FR (1)	FR2702480B1 (de)
GR (1)	GR3031330T3 (de)
HU (1)	HU219354B (de)
IL (1)	IL108622A (de)
MA (1)	MA23129A1 (de)
OA (1)	OA09892A (de)
RU (1)	RU2126803C1 (de)
TW (1)	TW353661B (de)
UA (1)	UA41871C2 (de)
ZA (1)	ZA941610B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5527780A (en) *	1992-11-05	1996-06-18	Roussel Uclaf	Erythromycin derivatives
FR2718450B1 (fr) *	1994-04-08	1997-01-10	Roussel Uclaf	Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.
GB9513756D0 (en) *	1995-07-06	1995-09-06	Smithkline Beecham Plc	Novel process & compounds
DE69733439T2 (de) *	1996-09-04	2006-05-04	Abbott Laboratories, Abbott Park	6-o-Substituierte Ketoliden mit antibakteriellen Wirkung
FR2760017B1 (fr) *	1997-02-27	1999-04-30	Hoechst Marion Roussel Inc	Nouveaux derives de l'erytromycine, leur procede de preparation et leur application comme medicaments
EE200100245A (et) *	1998-11-03	2002-10-15	Pfizer Products Inc.	Uued makroliidsed antibiootikumid
EE200100613A (et) *	1999-05-24	2003-02-17	Pfizer Products Inc.	13-metüülerütromütsiini derivaadid
US6573409B1 (en)	1999-07-02	2003-06-03	The Nutrasweet Company	Process for the preparation of 3,3-dimethylbutanal
WO2005007143A2 (en) *	2003-07-14	2005-01-27	The Board Of Trustees Of The University Of Illinois	Use of makrolides and ketolides for the treatment of tuberculosis

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR487411A (fr) *	1916-03-06	1918-07-03	Henri Dreyfus	Procédé pour la fabrication de l'aldéhyde acétique en partant de l'acétylène
FR2534588B2 (fr) *	1982-10-15	1985-09-20	Roussel Uclaf	Nouvelles oximes derivees de l'erythromycine, leur procede de preparation et leur application comme medicaments
EP0201166B1 (de) *	1985-03-12	1990-02-07	Beecham Group Plc	Erythromycin-Derivate
AU1204288A (en) *	1987-02-24	1988-08-25	Beecham Group Plc	Erythromycins
GB8729369D0 (en) *	1987-12-16	1988-01-27	Beecham Group Plc	Chemical compounds
IL99995A (en) *	1990-11-21	1997-11-20	Roussel Uclaf	Erythromycin derivatives, their preparation and pharmaceutical compositions containing them
US5912331A (en) *	1991-03-15	1999-06-15	Merck & Co., Inc.	Process for the preparation of 9-deoxo-9(Z)-hydroxyiminoerythromycin A
JPH089652B2 (ja) *	1991-04-03	1996-01-31	竹本油脂株式会社	ラジカル硬化性液状混合物、及びこれを含有するラジカル硬化性組成物、並びにこれらを硬化して得られる成形物

1993
- 1993-03-09 FR FR9302674A patent/FR2702480B1/fr not_active Expired - Lifetime
1994
- 1994-02-11 IL IL10862294A patent/IL108622A/en not_active IP Right Cessation
- 1994-03-07 US US08/207,355 patent/US5439889A/en not_active Expired - Lifetime
- 1994-03-08 EP EP94400491A patent/EP0614905B1/de not_active Expired - Lifetime
- 1994-03-08 CN CN94102533A patent/CN1040877C/zh not_active Expired - Lifetime
- 1994-03-08 ZA ZA941610A patent/ZA941610B/xx unknown
- 1994-03-08 CA CA002118564A patent/CA2118564C/fr not_active Expired - Lifetime
- 1994-03-08 FI FI941094A patent/FI110513B/fi not_active IP Right Cessation
- 1994-03-08 AT AT94400491T patent/ATE183190T1/de active
- 1994-03-08 DE DE69419950T patent/DE69419950T2/de not_active Expired - Lifetime
- 1994-03-08 HU HU9400679A patent/HU219354B/hu unknown
- 1994-03-08 DK DK94400491T patent/DK0614905T3/da active
- 1994-03-08 KR KR1019940004433A patent/KR100285972B1/ko not_active Expired - Lifetime
- 1994-03-08 ES ES94400491T patent/ES2135546T3/es not_active Expired - Lifetime
- 1994-03-09 JP JP06441694A patent/JP3228835B2/ja not_active Expired - Lifetime
- 1994-03-09 BR BR9400847A patent/BR9400847A/pt not_active Application Discontinuation
- 1994-03-09 RU RU94007342A patent/RU2126803C1/ru active
- 1994-03-09 OA OA60480A patent/OA09892A/fr unknown
- 1994-03-09 AU AU57639/94A patent/AU671708B2/en not_active Expired
- 1994-03-09 MA MA23436A patent/MA23129A1/fr unknown
- 1994-03-09 UA UA94005117A patent/UA41871C2/uk unknown
- 1994-04-01 TW TW083102896A patent/TW353661B/zh not_active IP Right Cessation
1999
- 1999-09-24 GR GR990402432T patent/GR3031330T3/el unknown

Also Published As

Publication number	Publication date
HU9400679D0 (en)	1994-06-28
JPH06321942A (ja)	1994-11-22
DE69419950T2 (de)	2000-01-13
KR940021571A (ko)	1994-10-19
DK0614905T3 (da)	2000-03-06
GR3031330T3 (en)	1999-12-31
TW353661B (en)	1999-03-01
ATE183190T1 (de)	1999-08-15
FR2702480A1 (fr)	1994-09-16
BR9400847A (pt)	1994-11-01
CA2118564A1 (fr)	1994-09-10
IL108622A0 (en)	1994-05-30
RU2126803C1 (ru)	1999-02-27
CN1108259A (zh)	1995-09-13
AU671708B2 (en)	1996-09-05
KR100285972B1 (ko)	2001-05-02
FI110513B (fi)	2003-02-14
OA09892A (fr)	1994-09-15
ES2135546T3 (es)	1999-11-01
CN1040877C (zh)	1998-11-25
DE69419950D1 (de)	1999-09-16
HUT71472A (en)	1995-11-28
UA41871C2 (uk)	2001-10-15
IL108622A (en)	1999-08-17
US5439889A (en)	1995-08-08
FI941094A0 (fi)	1994-03-08
AU5763994A (en)	1994-09-15
FR2702480B1 (fr)	1995-04-28
CA2118564C (fr)	2007-05-08
JP3228835B2 (ja)	2001-11-12
HU219354B (en)	2001-03-28
FI941094L (fi)	1994-09-10
EP0614905A1 (de)	1994-09-14
MA23129A1 (fr)	1994-10-01
EP0614905B1 (de)	1999-08-11

Publication	Publication Date	Title
CA2102457A1 (fr)	1994-05-06	Derives de l'erythromycine, leur procede de preparation, leur application comme medicaments
BG100951A (en)	1997-08-29	Novel erythromycin derivatives, method for their preparation and their use as drugs
AU554227B2 (en)	1986-08-14	Vicinal dihydroxyalkylxanthine derivatives
AU6052494A (en)	1994-10-27	3-deoxy oligosaccharides, processes for preparing them and pharmaceutical compositions containing them
IL108622A0 (en)	1994-05-30	New derivatives of erythromycin, their preparation process and their use as medicaments
AU583543B2 (en)	1989-05-04	New adamantanamine derivatives, processes for their preparation and drugs in which they are present
AU1960092A (en)	1993-01-14	Spicamycin derivatives and the use thereof
HUT57183A (en)	1991-11-28	Process for producing hydrazone derivatives and pharmaceutical preparatives containing said compounds
AU679132B2 (en)	1997-06-19	New eburnane analogues, a process for the preparation thereof and pharmaceutical compositions containing them
NZ335325A (en)	2000-08-25	Erythromycin derivatives, method for preparing them and their use as medicine
AU1234488A (en)	1988-09-01	New 2-(2,3-dihydro-2-oxo-3-benzofuranyl) acetic acid derivatives, processes for preparing them and the pharmaceutical compositions which contain them
ES8403109A1 (es)	1984-03-01	Un procedimiento para la preparacion de 4-(3-trifluormetilfenil)-1,2,3,6-tetrahidropiridinas.
PL297491A1 (en)	1993-08-09	Aryl hydroxyimidazolinylpropionamides
AU661622B2 (en)	1995-07-27	New P-(bis(2-chloroethyl)amino)phenylalanine compounds, process for preparing them and pharmaceutical compositions containing them
ZA901981B (en)	1990-11-28	Thienylacetic acid derivatives,process for the preparation thereof,the use thereof,and pharmaceuticals containing these and the preparation thereof
AU1234588A (en)	1988-09-01	New acetamides derived from 2,3-dihydro-3-phenyl-2-benzofuranone, processes for preparing them and the pharmaceutical compositions which contain them
ZA200100566B (en)	2002-12-24	Novel 6-deoxy erythromycin derivatives, method for preparing same and use as medicines.