ATE183995T1 - Herstellung von mit enantiomer angereicherten ortho-substituierten alpha, alpha-diaromatischen methanolen - Google Patents
Herstellung von mit enantiomer angereicherten ortho-substituierten alpha, alpha-diaromatischen methanolenInfo
- Publication number
- ATE183995T1 ATE183995T1 AT96903991T AT96903991T ATE183995T1 AT E183995 T1 ATE183995 T1 AT E183995T1 AT 96903991 T AT96903991 T AT 96903991T AT 96903991 T AT96903991 T AT 96903991T AT E183995 T1 ATE183995 T1 AT E183995T1
- Authority
- AT
- Austria
- Prior art keywords
- alpha
- diaromatic
- methanols
- enantiomer
- ortho
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 abstract 1
- LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/16—Preparation of optical isomers
- C07C231/18—Preparation of optical isomers by stereospecific synthesis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/08—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions not involving the formation of amino groups, hydroxy groups or etherified or esterified hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/56—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having carbon atoms of carboxamide groups bound to carbon atoms of carboxyl groups, e.g. oxamides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C37/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring
- C07C37/001—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by modification in a side chain
- C07C37/002—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by modification in a side chain by transformation of a functional group, e.g. oxo, carboxyl
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/390,255 US5646330A (en) | 1995-02-17 | 1995-02-17 | Production of enantiomerically enriched ortho-substituted α,α-diaromatic methanols |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE183995T1 true ATE183995T1 (de) | 1999-09-15 |
Family
ID=23541741
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT96903991T ATE183995T1 (de) | 1995-02-17 | 1996-02-06 | Herstellung von mit enantiomer angereicherten ortho-substituierten alpha, alpha-diaromatischen methanolen |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US5646330A (de) |
| EP (1) | EP0809626B1 (de) |
| JP (1) | JP3868488B2 (de) |
| AT (1) | ATE183995T1 (de) |
| AU (1) | AU4787696A (de) |
| CA (1) | CA2211981C (de) |
| DE (1) | DE69604054T2 (de) |
| WO (1) | WO1996025390A1 (de) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2008210455A1 (en) * | 2007-01-31 | 2008-08-07 | Vertex Pharmaceuticals Incorporated | 2-aminopyridine derivatives useful as kinase inhibitors |
| US8173635B2 (en) | 2007-11-02 | 2012-05-08 | Vertex Pharmaceuticals Incorporated | Kinase inhibitors |
| AU2009274011B2 (en) | 2008-07-23 | 2014-12-18 | Vertex Pharmaceuticals Incorporated | Pyrazolopyridine kinase inhibitors |
| US8569337B2 (en) | 2008-07-23 | 2013-10-29 | Vertex Pharmaceuticals Incorporated | Tri-cyclic pyrazolopyridine kinase inhibitors |
| CN102131809A (zh) | 2008-07-23 | 2011-07-20 | 沃泰克斯药物股份有限公司 | 三环吡唑并吡啶激酶抑制剂 |
| JP2011530527A (ja) * | 2008-08-06 | 2011-12-22 | バーテックス ファーマシューティカルズ インコーポレイテッド | アミノピリジンキナーゼ阻害剤 |
| MX2011011653A (es) | 2009-05-06 | 2012-01-20 | Vertex Pharma | Pirazolopiridinas. |
| AU2011209649A1 (en) | 2010-01-27 | 2012-08-09 | Vertex Pharmaceuticals Incorporated | Pyrazolopyrazine kinase inhibitors |
| CN102858769A (zh) | 2010-01-27 | 2013-01-02 | 沃泰克斯药物股份有限公司 | 吡唑并吡啶激酶抑制剂 |
| JP2013518114A (ja) | 2010-01-27 | 2013-05-20 | バーテックス ファーマシューティカルズ インコーポレイテッド | ピラゾロピリミジンキナーゼ阻害剤 |
| CN118772088B (zh) * | 2024-06-14 | 2025-10-03 | 北京农学院 | 2-丁烯羟酸内酯硫代乙酸酯类化合物及其制备方法和应用 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5043479A (en) * | 1986-08-29 | 1991-08-27 | Aldrich Chemical Company, Inc. | Chemically and optically pure diisopinocampheylhaloboranes |
| US4866181A (en) * | 1986-08-29 | 1989-09-12 | Aldrich-Boranes, Inc. | Process for producing optically active alcohols |
| US4772752A (en) * | 1986-08-29 | 1988-09-20 | Aldrich-Boranes, Inc. | Mono- and diisopinocampheylhaloboranes as new chiral reducing agents |
| US4868344A (en) * | 1988-03-30 | 1989-09-19 | Aldrich-Boranes, Inc. | Novel process of producing phenyl or substituted phenylalkylamine pharmaceutical agents and novel chiral intermediates of high enantiomeric purity useful therein |
| US4950791A (en) * | 1988-03-30 | 1990-08-21 | Brown Herbert C | Novel process of producing phenyl or substituted phenylalkylamine pharmaceutical agents and novel chiral intermediates of high enantiomeric purity useful therein |
| EP0580550B1 (de) * | 1992-07-21 | 1997-10-22 | Novartis AG | Oxamidsäure-Derivate als hypocholesterämische Mittel |
-
1995
- 1995-02-17 US US08/390,255 patent/US5646330A/en not_active Expired - Fee Related
-
1996
- 1996-02-06 DE DE69604054T patent/DE69604054T2/de not_active Expired - Fee Related
- 1996-02-06 AU AU47876/96A patent/AU4787696A/en not_active Abandoned
- 1996-02-06 WO PCT/EP1996/000479 patent/WO1996025390A1/en not_active Ceased
- 1996-02-06 EP EP96903991A patent/EP0809626B1/de not_active Expired - Lifetime
- 1996-02-06 AT AT96903991T patent/ATE183995T1/de not_active IP Right Cessation
- 1996-02-06 JP JP52462996A patent/JP3868488B2/ja not_active Expired - Fee Related
- 1996-02-06 CA CA002211981A patent/CA2211981C/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| WO1996025390A1 (en) | 1996-08-22 |
| JP3868488B2 (ja) | 2007-01-17 |
| CA2211981A1 (en) | 1996-08-22 |
| DE69604054D1 (de) | 1999-10-07 |
| DE69604054T2 (de) | 2000-01-27 |
| CA2211981C (en) | 2008-04-15 |
| JPH11500118A (ja) | 1999-01-06 |
| US5646330A (en) | 1997-07-08 |
| EP0809626B1 (de) | 1999-09-01 |
| EP0809626A1 (de) | 1997-12-03 |
| AU4787696A (en) | 1996-09-04 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| PT96857A (pt) | Processo para a preparacao de oxetanonas | |
| DE69525840D1 (de) | Herstellung von arthropodiziden oxadiazinen | |
| PT82127B (pt) | Processo para a preparacao de carbamatos de fenilo | |
| ATE205824T1 (de) | Verfahren zur herstellung von citalopram | |
| DE69604054D1 (de) | Herstellung von mit enantiomer angereicherten ortho-substituierten alpha, alpha-diaromatischen methanolen | |
| DE59409435D1 (de) | Verfahren zur Herstellung von 3-Arylbenzofuranonen | |
| BR9200627A (pt) | Processo para a preparacao de um composto e composto obtido | |
| SE9101482L (sv) | Foerfarande foer framstaellning av mellanprodukter anvaendbara foer syntes av bensotiazepiner | |
| EA199600007A2 (ru) | Новые трициклические производные, способ их получения, способы получения оптически активных или рацемических колхицина и тиоколхицина, их аналогов или производных с использованием трициклических соединений и промежуточные продукты синтеза | |
| IT1240833B (it) | Procedimento biocatalitico per la produzione di l-(-)- carnitina da crotonilbetaina e ceppi di proteeae per l'uso in tale procedimento | |
| BR9400016A (pt) | Processo para preparação de compostos, e compostos | |
| BR9401156A (pt) | Processo para a produção de um composto de alcoxiiminoacetamida | |
| ES2123728T3 (es) | Derivados de pirrolo-pirazina de actividad 5-ht3. | |
| ATE220685T1 (de) | Laktitolzusammensetzung und verfahren zu deren herstellung | |
| HUT53103A (en) | Process for the preparation of new 20,21-dinor-eburnamenine derivatives, new intermediates thereof, as well as pharmaceutical compositions containing said compounds as active ingredients | |
| ATE213734T1 (de) | Verfahren zur herstellung von 1,3- disubstituierten 2-nitroguanidinen | |
| DE59509183D1 (de) | Verfahren zur herstellung von n,n'-verbrückten bis-tetramethylpiperidinyl-verbindungen | |
| ATE207482T1 (de) | Verfahren zur herstellung von n2-arylsulfonyl-l- argininamiden | |
| ATE182140T1 (de) | Optisch aktive 1,4-dihydropyridinderivate sowie verfahren zu ihrer herstellung | |
| ATE188694T1 (de) | Verfahren zur herstellung von benzopyranderivaten | |
| DE69615200D1 (de) | Asymetrische synthese von r und s warfarin und deren ähnlichen verbindungen | |
| BR9406996A (pt) | Enanciômero processo para preparar o mesmo processo para ciclizar um composto e composto intermediário | |
| ATE111093T1 (de) | Verfahren zur herstellung von enantiomeren von 3- aminchromanderivaten. | |
| ATE399876T1 (de) | Chemoenzymatisches verfahren zur stereoselektiven herstellung von optisch-angereicherten phenylglycidate |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |