ATE184287T1 - Derivate von therapeutisch in der blutgerinnungskaskade wirksamen peptiden, verfahren zur herstellung und sie enthaltende pharmazeutische zubereitungen - Google Patents

Derivate von therapeutisch in der blutgerinnungskaskade wirksamen peptiden, verfahren zur herstellung und sie enthaltende pharmazeutische zubereitungen

Info

Publication number
ATE184287T1
ATE184287T1 AT94929585T AT94929585T ATE184287T1 AT E184287 T1 ATE184287 T1 AT E184287T1 AT 94929585 T AT94929585 T AT 94929585T AT 94929585 T AT94929585 T AT 94929585T AT E184287 T1 ATE184287 T1 AT E184287T1
Authority
AT
Austria
Prior art keywords
derivatives
production
therapeutically effective
pharmaceutical preparations
blood clotting
Prior art date
Application number
AT94929585T
Other languages
English (en)
Inventor
Jean-Luc Fauchere
Christophe Thurieau
Tony Verbeuren
Alain Rupin
Serge Simonet
Original Assignee
Adir
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adir filed Critical Adir
Application granted granted Critical
Publication of ATE184287T1 publication Critical patent/ATE184287T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/815—Protease inhibitors from leeches, e.g. hirudin, eglin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Diabetes (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
AT94929585T 1993-10-07 1994-10-06 Derivate von therapeutisch in der blutgerinnungskaskade wirksamen peptiden, verfahren zur herstellung und sie enthaltende pharmazeutische zubereitungen ATE184287T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9311942A FR2710917B1 (fr) 1993-10-07 1993-10-07 Nouveaux dérivés de peptides thérapeutiquement actifs dans la cascade de coagulation sanguine, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.

Publications (1)

Publication Number Publication Date
ATE184287T1 true ATE184287T1 (de) 1999-09-15

Family

ID=9451616

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94929585T ATE184287T1 (de) 1993-10-07 1994-10-06 Derivate von therapeutisch in der blutgerinnungskaskade wirksamen peptiden, verfahren zur herstellung und sie enthaltende pharmazeutische zubereitungen

Country Status (16)

Country Link
US (1) US5786330A (de)
EP (1) EP0722460B1 (de)
JP (1) JP2899415B2 (de)
CN (1) CN1053451C (de)
AT (1) ATE184287T1 (de)
AU (1) AU680696B2 (de)
CA (1) CA2173598A1 (de)
DE (1) DE69420574T2 (de)
DK (1) DK0722460T3 (de)
ES (1) ES2138668T3 (de)
FI (1) FI961505L (de)
FR (1) FR2710917B1 (de)
GR (1) GR3031254T3 (de)
NO (1) NO961357L (de)
NZ (1) NZ274524A (de)
WO (1) WO1995009869A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1138694A1 (de) * 2000-03-30 2001-10-04 University Of Manitoba Hirulog-ähnliches Peptid
DK1737889T3 (da) 2004-10-19 2011-01-03 Lonza Ag Fremgangsmåde til fastfase-peptidsyntese
US7598343B1 (en) 2008-07-27 2009-10-06 The Medicines Company Pharmaceutical formulations of bivalirudin and processes of making the same
US7582727B1 (en) 2008-07-27 2009-09-01 The Medicinces Company Pharmaceutical formulations of bivalirudin and processes of making the same

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2686086A1 (fr) * 1992-01-15 1993-07-16 Adir Nouveaux derives de peptides et de pseudopeptides therapeutiquement actifs dans la cascade de coagulation sanguine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.

Also Published As

Publication number Publication date
NO961357L (no) 1996-06-06
FI961505A0 (fi) 1996-04-03
FI961505A7 (fi) 1996-04-03
DE69420574D1 (de) 1999-10-14
FR2710917B1 (fr) 1995-11-24
WO1995009869A1 (fr) 1995-04-13
CN1053451C (zh) 2000-06-14
NO961357D0 (no) 1996-04-02
AU7858794A (en) 1995-05-01
DK0722460T3 (da) 2000-03-20
FI961505L (fi) 1996-04-03
GR3031254T3 (en) 1999-12-31
JPH09503221A (ja) 1997-03-31
AU680696B2 (en) 1997-08-07
CA2173598A1 (fr) 1995-04-13
DE69420574T2 (de) 2000-05-04
EP0722460B1 (de) 1999-09-08
CN1134706A (zh) 1996-10-30
EP0722460A1 (de) 1996-07-24
JP2899415B2 (ja) 1999-06-02
US5786330A (en) 1998-07-28
NZ274524A (en) 1996-12-20
FR2710917A1 (fr) 1995-04-14
ES2138668T3 (es) 2000-01-16

Similar Documents

Publication Publication Date Title
BG101118A (en) Therapeutical compounds
BR9714517A (pt) Cicloalquila, lactama, lactona e compostos correlatos, composições farmacêuticas compreendendo os mesmos e processos para inibir liberação de peptìdeo beta-amilóide e/ou sua sìntese por uso de tais compostos
IL127352A (en) Pyridyl alkene- and pyridyl alkine-acid amides and pharmaceutical compositions containing them
YU46097A (sh) Nova klasa estara i njihove farmaceutske smeše
GEP20012413B (en) Novel Substituted Cyclic Amino Acids as Pharmaceutical Agents
ATE204178T1 (de) Methode zur behandlung und vorbeugung von typ-1 diabetis durch orale verabreichung von insulin
RU94046251A (ru) Глюкагоноподобный пептид и производные инсулино-тропина, способ получений, фармацевтические композиции, способы лечения диабета
DE69636343D1 (de) Verwendung von glu-trp dipeptiden zur herstellung eines arzneimittels zur behandlung von verschiedenen gefässneubildung-assozierten erkrankungen
HUP0000492A1 (hu) N-(Aril/heteroaril-acetil)-aminosav-észterek, azokat tartalmazó gyógyászati készítmények, valamint módszerek béta-amiloid fehérje képződése és felszabadulása gátlására e vegyületek felhasználásával
DE69410254D1 (de) Behandlung von mycobakteriellen erkrankungen durch verabreichung von bakrerientötende, durchlässigkeitserhöhende proteinfragmente
DE69326954D1 (de) Amphiphile verbindungen abgegleitet von aminosäuren oder peptiden, verfahren zu ihrer herstellung und ihre verwendung als arzeimittelverabreichung
RU95111308A (ru) Производные 2-амино-4-фенил-4-оксомасляной кислоты, способы получения, фармацевтическая композиция
BG103219A (bg) Бензамидинови производни и използването им като лекарствени средства с ltb4-антагонистично действие
RU93045145A (ru) Замещенные производные циклогексана и их применение для лечения заболеваний, содержащее их лекарственное средство
ES2160643T3 (es) Composiciones que contienen g-csf y proteina de union al tnf.
ATE439833T1 (de) Pharmazeutische zubereitung enthaltend ein catechin, ascorbinsäure, prolin und lysin zur behandlung von neoplastischen krankheiten
DE69900756D1 (de) Verwendung von hmg proteinen zur herstellung von arzneimitteln mit zytotoxischer wirkung
BR9809234A (pt) Composto, composição farmacêutica, uso de um composto, processos para tratar ou prevenir doenças do sistema endocrinológico, para fabricar um medicamento, para preparar um composto e um conjunto, conjunto, e, uso do mesmo.
ATE184287T1 (de) Derivate von therapeutisch in der blutgerinnungskaskade wirksamen peptiden, verfahren zur herstellung und sie enthaltende pharmazeutische zubereitungen
RU94046300A (ru) Химические соединения, способ их получения, фармкомпозиция, способ лечения, промежуточный продукт
EE9600109A (et) a-amino- ja tsüklopentaan-ß-aminohapet(-happeid) ja/või nende derivaate sisaldavad segud ja dipeptiidid, dipeptiidide valmistamismeetod ning nimetatud segusid ja/või dipeptiide sisaldavad ravimid
ATE194076T1 (de) Verwendung von n,s-diacetylcystein-ethylester (dacee) zur herstellung eines medikaments zur behandlung viraler erkrankungen
SE9700244D0 (sv) Novel antibacterial protein
DK82892D0 (da) Anvendelse af braadgifte fra bier og hvepse til fremstilling af laegemidler til behandling af infektioner
EA200401295A1 (ru) Статиновая терапия для усиления поддержания когнитивной функции

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee