ATE184473T1 - Verwendung von glyzerin zur dämpfung der transdermalen arzneimittelverabreichung - Google Patents

Verwendung von glyzerin zur dämpfung der transdermalen arzneimittelverabreichung

Info

Publication number
ATE184473T1
ATE184473T1 AT93913793T AT93913793T ATE184473T1 AT E184473 T1 ATE184473 T1 AT E184473T1 AT 93913793 T AT93913793 T AT 93913793T AT 93913793 T AT93913793 T AT 93913793T AT E184473 T1 ATE184473 T1 AT E184473T1
Authority
AT
Austria
Prior art keywords
drug
application
transdermal
delivery
glycerin
Prior art date
Application number
AT93913793T
Other languages
English (en)
Inventor
Werner E Heiber
Charles D Ebert
Dinesh C Patel
Srinivasan Venkateshwaran
Original Assignee
Theratech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Theratech Inc filed Critical Theratech Inc
Application granted granted Critical
Publication of ATE184473T1 publication Critical patent/ATE184473T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7069—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M35/00—Devices for applying media, e.g. remedies, on the human body

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT93913793T 1992-06-11 1993-05-03 Verwendung von glyzerin zur dämpfung der transdermalen arzneimittelverabreichung ATE184473T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US89726992A 1992-06-11 1992-06-11

Publications (1)

Publication Number Publication Date
ATE184473T1 true ATE184473T1 (de) 1999-10-15

Family

ID=25407656

Family Applications (1)

Application Number Title Priority Date Filing Date
AT93913793T ATE184473T1 (de) 1992-06-11 1993-05-03 Verwendung von glyzerin zur dämpfung der transdermalen arzneimittelverabreichung

Country Status (13)

Country Link
EP (1) EP0644746B1 (de)
JP (1) JPH08501529A (de)
KR (1) KR950701508A (de)
AT (1) ATE184473T1 (de)
AU (1) AU677206B2 (de)
CA (1) CA2135925C (de)
DE (1) DE69326461T2 (de)
DK (1) DK0644746T3 (de)
ES (1) ES2137993T3 (de)
GR (1) GR3031246T3 (de)
HU (1) HU221598B (de)
NZ (1) NZ253409A (de)
WO (1) WO1993025168A1 (de)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4429667C2 (de) * 1994-08-20 1996-07-11 Lohmann Therapie Syst Lts Estradiol-TTS mit wasserbindenden Zusätzen und Verfahren zu seiner Herstellung
US5601839A (en) * 1995-04-26 1997-02-11 Theratech, Inc. Triacetin as a penetration enhancer for transdermal delivery of a basic drug
DE19517145C2 (de) * 1995-05-10 2000-02-24 Hexal Pharmaforschung Gmbh Transdermales therapeutisches System (TTS) zur Verabreichung von Testosteron
US6572879B1 (en) * 1995-06-07 2003-06-03 Alza Corporation Formulations for transdermal delivery of pergolide
DE69630918T2 (de) 1995-06-09 2004-10-28 Hisamitsu Pharmaceutical Co., Inc., Tosu Matrix für Iontophorese
CA2208336A1 (en) * 1996-06-20 1997-12-20 Hisamitsu Pharmaceuticals Co., Inc. A device structure for iontophoresis
US5968547A (en) 1997-02-24 1999-10-19 Euro-Celtique, S.A. Method of providing sustained analgesia with buprenorphine
IT1294748B1 (it) 1997-09-17 1999-04-12 Permatec Tech Ag Formulazione per un dispositivo transdermico
ATE418988T1 (de) * 1997-11-10 2009-01-15 Strakan Int Ltd Penetrationsfördernde und irritationsvermindernde systeme mit testosteron
DE10019311A1 (de) * 2000-04-19 2001-10-31 Lohmann Therapie Syst Lts Transdermale therapuetische Systeme zur Applikation von Moxonidin
US6503894B1 (en) 2000-08-30 2003-01-07 Unimed Pharmaceuticals, Inc. Pharmaceutical composition and method for treating hypogonadism
US20030139384A1 (en) * 2000-08-30 2003-07-24 Dudley Robert E. Method for treating erectile dysfunction and increasing libido in men
PT1315502E (pt) * 2000-08-30 2010-05-06 Unimed Pharmaceuticals Llc Método para tratar a disfunção eréctil e para aumentar a líbido em homens
CA2489865C (en) 2002-06-25 2012-05-08 Acrux Dds Pty Ltd Transdermal delivery rate control using amorphous pharmaceutical compositions
IL152486A0 (en) 2002-10-25 2003-05-29 Meir Eini Alcohol-free cosmetic and pharmaceutical foam carrier
AU2003279493B2 (en) 2002-10-25 2009-08-20 Foamix Pharmaceuticals Ltd. Cosmetic and pharmaceutical foam
US9668972B2 (en) 2002-10-25 2017-06-06 Foamix Pharmaceuticals Ltd. Nonsteroidal immunomodulating kit and composition and uses thereof
US10117812B2 (en) 2002-10-25 2018-11-06 Foamix Pharmaceuticals Ltd. Foamable composition combining a polar solvent and a hydrophobic carrier
US9265725B2 (en) 2002-10-25 2016-02-23 Foamix Pharmaceuticals Ltd. Dicarboxylic acid foamable vehicle and pharmaceutical compositions thereof
US7704518B2 (en) 2003-08-04 2010-04-27 Foamix, Ltd. Foamable vehicle and pharmaceutical compositions thereof
JO2492B1 (en) * 2003-04-28 2009-10-05 شيرينج ايه جي A pharmaceutical formula in the form of aqueous gel for the skin use of its active ingredients
US7879357B2 (en) 2003-04-28 2011-02-01 Bayer Schering Pharma Ag Pharmaceutical composition in the form of a hydrogel for transdermal administration of active ingredients
KR20130114229A (ko) 2005-06-03 2013-10-16 애크럭스 디디에스 피티와이 리미티드 경피 약물 전달 방법 및 조성물
US8147815B2 (en) * 2005-12-16 2012-04-03 Celmatrix Corporation Topical administration carrier composition and therapeutic formulations comprising same
US20080260655A1 (en) 2006-11-14 2008-10-23 Dov Tamarkin Substantially non-aqueous foamable petrolatum based pharmaceutical and cosmetic compositions and their uses
CA2674661C (en) 2007-01-11 2016-10-11 Acrux Dds Pty Ltd Spreading implement
US8636982B2 (en) 2007-08-07 2014-01-28 Foamix Ltd. Wax foamable vehicle and pharmaceutical compositions thereof
WO2009090495A2 (en) 2007-12-07 2009-07-23 Foamix Ltd. Oil and liquid silicone foamable carriers and formulations
FR2924942B1 (fr) * 2007-12-14 2012-06-15 Pf Medicament Compositions pharmaceutiques transcutanees contenant une hormone steroidienne
WO2010125470A2 (en) 2009-04-28 2010-11-04 Foamix Ltd. Foamable vehicle and pharmaceutical compositions comprising aprotic polar solvents and uses thereof
PL2952191T3 (pl) 2009-06-12 2019-02-28 Sunovion Pharmaceuticals Inc. Apomorfina w postaci do podawania podjęzykowego
WO2011013009A2 (en) 2009-07-29 2011-02-03 Foamix Ltd. Non surfactant hydro-alcoholic foamable compositions, breakable foams and their uses
CA2769677A1 (en) 2009-07-29 2011-02-03 Foamix Ltd. Non surface active agent non polymeric agent hydro-alcoholic foamable compositions, breakable foams and their uses
MX359879B (es) 2009-10-02 2018-10-12 Foamix Pharmaceuticals Ltd Composiciones tópicas de tetraciclina.
US9849142B2 (en) 2009-10-02 2017-12-26 Foamix Pharmaceuticals Ltd. Methods for accelerated return of skin integrity and for the treatment of impetigo
EA031156B1 (ru) 2010-12-16 2018-11-30 Суновион Фармасьютикалз Инк. Сублингвальные пленки
TWI576111B (zh) * 2011-02-25 2017-04-01 久光製藥股份有限公司 用於經皮或經黏膜投予之佐劑及含有該佐劑之醫藥製劑
JP6114401B2 (ja) 2013-10-31 2017-04-12 久光製薬株式会社 アジュバント組成物、これを含むアジュバント製剤、及びキット
USD750788S1 (en) 2013-11-26 2016-03-01 Acrux Dds Pty Ltd Topical spreading applicator
USD749225S1 (en) 2013-11-26 2016-02-09 Acrux Dds Pty Ltd Topical spreading applicator
US8785426B1 (en) 2013-12-13 2014-07-22 Upsher-Smith Laboratories, Inc. Testosterone gel compositions and related methods
EP3285771B1 (de) 2015-04-21 2025-02-12 Sunovion Pharmaceuticals Inc. Verfahren zur behandlung von morbus parkinson durch verabreichung von apomorphin an eine mundschleimhaut
CA2978573A1 (en) 2016-09-08 2018-03-08 Foamix Pharmaceuticals Ltd. Compositions and methods for treating rosacea and acne
US9962444B2 (en) 2016-09-27 2018-05-08 Shane Malek Pharmacokinetically extended action topical hair growth formulation, and administration method

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2920500A1 (de) * 1979-05-21 1980-11-27 Boehringer Sohn Ingelheim Pharmazeutische zubereitung in form eines polyacrylatfilmes
JPS6272611A (ja) * 1985-09-27 1987-04-03 Kao Corp 皮膚外用剤
US5059189A (en) * 1987-09-08 1991-10-22 E. R. Squibb & Sons, Inc. Method of preparing adhesive dressings containing a pharmaceutically active ingredient
US4855294A (en) * 1988-09-06 1989-08-08 Theratech, Inc. Method for reducing skin irritation associated with drug/penetration enhancer compositions
GB9016056D0 (en) * 1990-07-21 1990-09-05 Chatfield Pharmaceuticals Limi Transdermal medicine delivery devices
DE4210165A1 (de) * 1991-07-30 1993-02-04 Schering Ag Transdermale therapeutische systeme
US5405366A (en) * 1991-11-12 1995-04-11 Nepera, Inc. Adhesive hydrogels having extended use lives and process for the preparation of same

Also Published As

Publication number Publication date
DK0644746T3 (da) 1999-12-20
JPH08501529A (ja) 1996-02-20
CA2135925C (en) 2001-04-10
DE69326461D1 (de) 1999-10-21
WO1993025168A1 (en) 1993-12-23
NZ253409A (en) 1996-09-25
AU4369493A (en) 1994-01-04
CA2135925A1 (en) 1993-12-23
EP0644746B1 (de) 1999-09-15
AU677206B2 (en) 1997-04-17
KR950701508A (ko) 1995-04-28
HU221598B (hu) 2002-11-28
DE69326461T2 (de) 2000-05-04
GR3031246T3 (en) 1999-12-31
EP0644746A1 (de) 1995-03-29
EP0644746A4 (de) 1995-09-13
HU9403555D0 (en) 1995-02-28
ES2137993T3 (es) 2000-01-01
HUT71521A (en) 1995-12-28

Similar Documents

Publication Publication Date Title
ATE184473T1 (de) Verwendung von glyzerin zur dämpfung der transdermalen arzneimittelverabreichung
US5614211A (en) Oxybutynin transdermal device having decreased delamination
US5238933A (en) Skin permeation enhancer compositions
PT922453E (pt) Preparacao do tipo de absorcao percutanea contendo tulobuterol
BR9713492A (pt) ésteres de ácido graxo de ácido glicólico e seus sais como realçadores de permeação
LU91972I2 (fr) Fentanyl et applicateur-doseur
DK567088A (da) Indretning til transdermal laegemiddelindgift
NZ306249A (en) matrix patch containing triacetin as a transdermal pentration enhancer
DE3277453D1 (en) Use of eucalyptol for enhancing skin permeation of bioaffecting agents
GR1001025B (el) Μεθοδος δια διαδερμικην (υποδοριον παροχην ibuprofen, δια χρησιμοποιησεως υδραλκοολικου πυκτωματος (γελης).
DK626484D0 (da) Systemer til afgivelse af virksomme stoffer
LU86929A1 (de) Neue topisch applizierbare pharmazeutische zusammensetzungen mit systemischer wirkung
KR850700218A (ko) 약학 조성물
NZ332746A (en) Transdermal propentofylline compositions for the treatment of Alzheimer's disease
GB2163956A (en) Percutaneous anaesthetic composition for topical application
JPH03505835A (ja) 経皮ドラッグデリバリーシステム
RU94010496A (ru) Ноотропное средство и лекарственный состав ноотропного средства
Hollingsbee et al. The effect of a hydrocolloid dermatological patch (Actiderm) in potentiating the skin blanching activity of triamcinolone acetonide
TWI243689B (en) Transdermal patch using hydrophilic polymer as matrix