ATE184485T1 - Verwendung der 1-4-4-aryl(oder heteroaryl)-1- piperazinylbutyl-1h-azol-derivate zur herstellung von arzneimitteln zur behandlung der störungen der magensekretion - Google Patents
Verwendung der 1-4-4-aryl(oder heteroaryl)-1- piperazinylbutyl-1h-azol-derivate zur herstellung von arzneimitteln zur behandlung der störungen der magensekretionInfo
- Publication number
- ATE184485T1 ATE184485T1 AT94402673T AT94402673T ATE184485T1 AT E184485 T1 ATE184485 T1 AT E184485T1 AT 94402673 T AT94402673 T AT 94402673T AT 94402673 T AT94402673 T AT 94402673T AT E184485 T1 ATE184485 T1 AT E184485T1
- Authority
- AT
- Austria
- Prior art keywords
- heteroaryl
- aryl
- treatment
- piperazinylbutyl
- production
- Prior art date
Links
- 230000002496 gastric effect Effects 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 230000028327 secretion Effects 0.000 title abstract 2
- 229940126601 medicinal product Drugs 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 125000001072 heteroaryl group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9314102A FR2712808B1 (fr) | 1993-11-25 | 1993-11-25 | Utilisation des dérivés de 1-{4-[4-aryl(ou hétéroaryl)-1-pipérazinyl]-butyl}-1-H-azole pour la préparation de médicaments destinés au traitement des troubles de la sécrétion gastrique . |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE184485T1 true ATE184485T1 (de) | 1999-10-15 |
Family
ID=9453220
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT94402673T ATE184485T1 (de) | 1993-11-25 | 1994-11-23 | Verwendung der 1-4-4-aryl(oder heteroaryl)-1- piperazinylbutyl-1h-azol-derivate zur herstellung von arzneimitteln zur behandlung der störungen der magensekretion |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US5532234A (de) |
| EP (1) | EP0655248B1 (de) |
| JP (1) | JPH07242626A (de) |
| AT (1) | ATE184485T1 (de) |
| AU (1) | AU674458B2 (de) |
| CA (1) | CA2136661A1 (de) |
| DE (1) | DE69420679D1 (de) |
| ES (1) | ES2089974B1 (de) |
| FR (1) | FR2712808B1 (de) |
| ZA (1) | ZA949332B (de) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5681956A (en) * | 1990-12-28 | 1997-10-28 | Neurogen Corporation | 4-aryl substituted piperazinylmethyl phenylimidazole derivatives; a new class of dopamine receptor subtype specific ligands |
| US5656762A (en) | 1990-12-28 | 1997-08-12 | Neurogen Corporation | 4-piperidino-and piperazinomethyl-2-phenylimidazole derivatives, dopamine receptor subtype specific ligands |
| WO1997003058A1 (en) * | 1995-07-07 | 1997-01-30 | Taisho Pharmaceutical Co., Ltd. | 4-alkylthiazoline derivatives |
| FR2763950B1 (fr) * | 1997-06-02 | 2002-09-20 | Esteve Labor Dr | 2- {4- [4-(4,5-dichloro-2-methylimidazol-1-yl)butyl] -1- piperazinyl }-5-fluoropyrimidine, sa preparation et son utilisation therapeutique |
| US6166205A (en) * | 1998-09-02 | 2000-12-26 | Neurogen Corporation | 2-Aryl-4-(1-[4-heteroaryl]piperazin-1-yl)methylimidazoles: dopamine . D.sub4 receptor subtype ligands |
| US6335343B1 (en) * | 1999-03-03 | 2002-01-01 | Merck & Co., Inc. | Inhibitors of prenyl-protein transferase |
| NZ524192A (en) | 2000-08-14 | 2005-02-25 | Ortho Mcneil Pharm Inc | Substituted pyrazoles |
| US7332494B2 (en) | 2000-08-14 | 2008-02-19 | Janssen Pharmaceutica, N.V. | Method for treating allergies using substituted pyrazoles |
| RU2317988C2 (ru) | 2000-08-14 | 2008-02-27 | Орто-Макнейл Фармасьютикал, Инк. | Замещенные пиразолы, фармацевтическая композиция на их основе, применение фармацевтической композиции и способ ингибирования активности катепсина s |
| EP1309591B1 (de) | 2000-08-14 | 2007-01-24 | Ortho-McNeil Pharmaceutical, Inc. | Substituierte pyrazole |
| HK1053129A1 (zh) | 2000-09-06 | 2003-10-10 | Ortho-Mcneil Pharmaceutical, Inc. | 治疗变态反应的方法 |
| GB2435827A (en) * | 2006-03-09 | 2007-09-12 | Del Dr Esteve S A Spain Lab | Use of substituted piperazine compounds for the treatment of food related disorders |
| US9802929B2 (en) * | 2012-11-26 | 2017-10-31 | Shenyang Haiwang Biotechnology Co., Ltd. | Benzo five-membered nitrogen heterocyclic piperidine or piperazine derivatives and preparation methods and pharmaceutical compositions thereof |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2672052B1 (fr) * | 1991-01-28 | 1995-05-24 | Esteve Labor Dr | Derives d'aryl (ou heteroaryl)-piperazinyl-alkyl-azoles, leur preparation et leur application en tant que medicaments. |
| US5096908A (en) * | 1990-05-04 | 1992-03-17 | Eli Lilly And Company | Method of inhibiting gastric acid secretion |
-
1993
- 1993-11-25 FR FR9314102A patent/FR2712808B1/fr not_active Expired - Fee Related
-
1994
- 1994-11-23 EP EP94402673A patent/EP0655248B1/de not_active Expired - Lifetime
- 1994-11-23 DE DE69420679T patent/DE69420679D1/de not_active Expired - Lifetime
- 1994-11-23 US US08/344,377 patent/US5532234A/en not_active Expired - Fee Related
- 1994-11-23 AT AT94402673T patent/ATE184485T1/de active
- 1994-11-24 ES ES09402417A patent/ES2089974B1/es not_active Expired - Lifetime
- 1994-11-24 ZA ZA949332A patent/ZA949332B/xx unknown
- 1994-11-24 AU AU79007/94A patent/AU674458B2/en not_active Ceased
- 1994-11-25 JP JP6290838A patent/JPH07242626A/ja active Pending
- 1994-11-25 CA CA002136661A patent/CA2136661A1/fr not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| ES2089974B1 (es) | 1997-03-16 |
| US5532234A (en) | 1996-07-02 |
| ES2089974A1 (es) | 1996-10-01 |
| DE69420679D1 (de) | 1999-10-21 |
| ZA949332B (en) | 1995-11-14 |
| EP0655248B1 (de) | 1999-09-15 |
| JPH07242626A (ja) | 1995-09-19 |
| AU674458B2 (en) | 1996-12-19 |
| EP0655248A1 (de) | 1995-05-31 |
| FR2712808A1 (fr) | 1995-06-02 |
| AU7900794A (en) | 1995-06-01 |
| FR2712808B1 (fr) | 1996-02-16 |
| CA2136661A1 (fr) | 1995-05-26 |
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