ATE184610T1 - Thiazolo(5,4-b>azepinverbindungen - Google Patents

Thiazolo(5,4-b>azepinverbindungen

Info

Publication number
ATE184610T1
ATE184610T1 AT89113362T AT89113362T ATE184610T1 AT E184610 T1 ATE184610 T1 AT E184610T1 AT 89113362 T AT89113362 T AT 89113362T AT 89113362 T AT89113362 T AT 89113362T AT E184610 T1 ATE184610 T1 AT E184610T1
Authority
AT
Austria
Prior art keywords
substituted
thiazolo
azepine compounds
group
hydrogen atom
Prior art date
Application number
AT89113362T
Other languages
English (en)
Inventor
Tetsuya Aono
Masahiro Suno
Go Kito
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Application granted granted Critical
Publication of ATE184610T1 publication Critical patent/ATE184610T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Vascular Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT89113362T 1988-07-22 1989-07-20 Thiazolo(5,4-b>azepinverbindungen ATE184610T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP18422088 1988-07-22
JP8653689 1989-04-05

Publications (1)

Publication Number Publication Date
ATE184610T1 true ATE184610T1 (de) 1999-10-15

Family

ID=26427638

Family Applications (1)

Application Number Title Priority Date Filing Date
AT89113362T ATE184610T1 (de) 1988-07-22 1989-07-20 Thiazolo(5,4-b>azepinverbindungen

Country Status (11)

Country Link
US (3) US4956360A (de)
EP (1) EP0351856B1 (de)
JP (1) JP3054738B2 (de)
KR (1) KR970011396B1 (de)
AT (1) ATE184610T1 (de)
AU (1) AU610739B2 (de)
CA (1) CA1336431C (de)
DE (1) DE68929074T2 (de)
DK (1) DK362889A (de)
IL (1) IL91063A (de)
NZ (1) NZ230042A (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL89351A0 (en) * 1988-03-14 1989-09-10 Lundbeck & Co As H 4,5,6,7-tetrahydroisothiazolo(4,5-c)pyridines,process for their preparation and pharmaceutical compositions containing them
DE3820775A1 (de) * 1988-06-20 1989-12-21 Thomae Gmbh Dr K Neue 4,5,7,8-tetrahydro-6h-thiazolo(5,4,-d)azepine, ihre herstellung und ihre verwendung als arzneimittel
DE4134467A1 (de) * 1991-10-18 1993-04-22 Thomae Gmbh Dr K Heterobiarylderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
IL97249A (en) * 1990-02-23 1995-01-24 Takeda Chemical Industries Ltd Compounds of 7,6,5,4-tetrahydrothiazole] B-5,4 [pyridine and compounds of 5,6-dihydro-H4-pyrrolo] D-3,2 [thiazole, their manufacture, and pharmaceutical compositions including or
RU2124503C1 (ru) * 1992-05-18 1999-01-10 И.Р.Сквибб энд Санз, Инк. Гетероциклические азотсодержащие производные карбоновой кислоты, способ их получения и фармацевтическая композиция
GB9219779D0 (en) * 1992-09-18 1992-10-28 Rhone Poulenc Agriculture Compositions of new matter
DE4324580A1 (de) * 1993-07-22 1995-01-26 Thomae Gmbh Dr K Bicyclische Heterocyclen, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung
WO1996036347A1 (en) * 1995-05-17 1996-11-21 Eli Lilly And Company Use of leukotriene antagonists for alzheimer's disease
US5891460A (en) * 1995-06-07 1999-04-06 University Of Southern California University Park Campus Method for reducing or preventing post-surgical adhesion formation using ketotifen and analogs thereof
GB2312621B (en) * 1996-05-02 1998-03-11 Pharma Nord Uk Limited Anti-oxidant medicament
US6433935B2 (en) 1996-07-02 2002-08-13 Three-Five Systems, Inc. Display illumination system
AU5886500A (en) * 1999-06-23 2001-01-09 Sepracor, Inc. Indolyl-benzimidazole antibacterials, and methods of use thereof
US6649318B1 (en) 2000-04-20 2003-11-18 Eastman Kodak Company Self-contained imaging media comprising microencapsulated color formers and a resilient layer
RU2188824C1 (ru) * 2000-12-18 2002-09-10 Военно-медицинская академия 2-амино-4-ацетилтиазоло[5,4-b]индол, защищающий организм от воздействия гипоксии и токсического отека легкого
EP1424101A3 (de) * 2002-11-29 2004-08-18 NOZAKI, Masako Verwendung eines Leukotrien- C4/ D4 -rezeptorantagonisten zur Herstellung eines Medikamentes zur Behandlung oder Vorbeugung von Gehirnentzündung und -sepsis
US7148248B2 (en) 2002-11-29 2006-12-12 Masako Nozaki Method of treating or inhibiting the development of brain inflammation and sepsis
WO2005053702A2 (en) * 2003-12-01 2005-06-16 Cambridge University Technical Services Limited Anti-inflammatory agents
RU2281950C2 (ru) * 2004-09-21 2006-08-20 Военно-медицинская академия им. С.М. Кирова 4-АЦЕТИЛТИАЗОЛО[5,4-b]ИНДОЛ-2-СУКЦИНИМИД, ЗАЩИЩАЮЩИЙ ОРГАНИЗМ ОТ ГИПОКСИИ И ОБЛАДАЮЩИЙ ПРОФИЛАКТИЧЕСКИМ ДЕЙСТВИЕМ В ОТНОШЕНИИ ТОКСИЧЕСКОГО ОТЕКА ЛЕГКОГО
EP1896036B1 (de) 2005-06-15 2013-01-23 Cambridge Enterprise Limited Entzündungshemmende mittel
GB201009603D0 (en) * 2010-06-08 2010-07-21 Cambridge Entpr Ltd Anti-inflammatory agent

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BG17786A3 (bg) * 1970-08-14 1973-12-25 Dr. Karl Thomae Gmbh Метод за получаване на нови производни на азепина
JPS53121781A (en) * 1977-03-30 1978-10-24 Torii Yakuhin Kk Caprolactum derivatives
AU554388B2 (en) * 1981-06-15 1986-08-21 American Home Products Corporation Alpha-phenyl-2-(aza)benzothiazolylthioglycolic acid derivatives
JPS5837097A (ja) * 1981-08-28 1983-03-04 味の素株式会社 界面活性剤
JPS63283591A (ja) * 1986-12-17 1988-11-21 Toray Ind Inc Ｌ−α−アミノ−ε−カプロラクタムの製造法

Also Published As

Publication number Publication date
JPH0347188A (ja) 1991-02-28
IL91063A0 (en) 1990-02-09
CA1336431C (en) 1995-07-25
EP0351856B1 (de) 1999-09-15
DK362889D0 (da) 1989-07-21
KR970011396B1 (ko) 1997-07-10
EP0351856A2 (de) 1990-01-24
AU610739B2 (en) 1991-05-23
NZ230042A (en) 1990-10-26
AU3886289A (en) 1990-01-25
KR910002873A (ko) 1991-02-26
EP0351856A3 (de) 1991-08-07
US4956360A (en) 1990-09-11
US5118806A (en) 1992-06-02
DE68929074T2 (de) 2000-01-05
DE68929074D1 (de) 1999-10-21
DK362889A (da) 1990-01-23
IL91063A (en) 1994-12-29
JP3054738B2 (ja) 2000-06-19
US5300639A (en) 1994-04-05

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties