ATE186567T1 - Verwendung von azolen als virustötende substanzen in lösungen von biologisch aktiven proteinen - Google Patents

Verwendung von azolen als virustötende substanzen in lösungen von biologisch aktiven proteinen

Info

Publication number
ATE186567T1
ATE186567T1 AT95104636T AT95104636T ATE186567T1 AT E186567 T1 ATE186567 T1 AT E186567T1 AT 95104636 T AT95104636 T AT 95104636T AT 95104636 T AT95104636 T AT 95104636T AT E186567 T1 ATE186567 T1 AT E186567T1
Authority
AT
Austria
Prior art keywords
biologically active
azoles
virus
solutions
active proteins
Prior art date
Application number
AT95104636T
Other languages
English (en)
Inventor
Milton B Dobkin
Paul K Ng
George B Dove
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22849553&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE186567(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bayer Ag filed Critical Bayer Ag
Application granted granted Critical
Publication of ATE186567T1 publication Critical patent/ATE186567T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Disinfection or sterilisation of materials or objects, in general; Accessories therefor
    • A61L2/16—Disinfection or sterilisation of materials or objects, in general; Accessories therefor using chemical substances
    • A61L2/18—Liquid substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2103/00—Materials or objects being the target of disinfection or sterilisation
    • A61L2103/05—Living organisms or biological materials
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
    • C12N2720/00011—Details
    • C12N2720/12011—Reoviridae
    • C12N2720/12061—Methods of inactivation or attenuation
    • C12N2720/12063—Methods of inactivation or attenuation by chemical treatment
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/20011—Rhabdoviridae
    • C12N2760/20211—Vesiculovirus, e.g. vesicular stomatitis Indiana virus
    • C12N2760/20261—Methods of inactivation or attenuation
    • C12N2760/20263—Methods of inactivation or attenuation by chemical treatment
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/32011—Picornaviridae
    • C12N2770/32611—Poliovirus
    • C12N2770/32661—Methods of inactivation or attenuation
    • C12N2770/32663—Methods of inactivation or attenuation by chemical treatment

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
AT95104636T 1994-04-11 1995-03-29 Verwendung von azolen als virustötende substanzen in lösungen von biologisch aktiven proteinen ATE186567T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/226,593 US5514781A (en) 1994-04-11 1994-04-11 Use of azoles as virucidal agents in solutions of biologically active proteins

Publications (1)

Publication Number Publication Date
ATE186567T1 true ATE186567T1 (de) 1999-11-15

Family

ID=22849553

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95104636T ATE186567T1 (de) 1994-04-11 1995-03-29 Verwendung von azolen als virustötende substanzen in lösungen von biologisch aktiven proteinen

Country Status (12)

Country Link
US (1) US5514781A (de)
EP (1) EP0686694B1 (de)
JP (1) JP3735137B2 (de)
CN (1) CN1129139A (de)
AT (1) ATE186567T1 (de)
AU (1) AU687153B2 (de)
CA (1) CA2144674C (de)
DE (1) DE69513226T2 (de)
DK (1) DK0686694T3 (de)
ES (1) ES2139769T3 (de)
GR (1) GR3032546T3 (de)
SI (1) SI0686694T1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1115411C (zh) * 1998-01-26 2003-07-23 邹方霖 一种新型的灭活病毒的方法
AUPP751298A0 (en) * 1998-12-04 1999-01-07 Csl Limited Inactivation of non-enveloped viruses
EP1820516B1 (de) 1999-02-22 2013-07-24 University of Connecticut Neue albuminfreie Faktor VIII Formulierungen
DE102004015007A1 (de) * 2004-03-26 2005-10-13 Bayer Healthcare Ag Substituierte Imidazole
EP2385825B1 (de) 2008-11-07 2018-10-10 University of Connecticut Faktor-viii-formulierungen
WO2019086463A1 (en) 2017-10-30 2019-05-09 Baxalta GmbH Environmentally compatible detergents for inactivation of lipid-enveloped viruses

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS56113713A (en) * 1980-02-14 1981-09-07 Chemo Sero Therapeut Res Inst Preparation of immunoglobulin with high content of monomer
DE3315808A1 (de) * 1983-04-30 1984-10-31 Bayer Ag, 5090 Leverkusen Antivirale mittel
US4861791A (en) * 1983-08-29 1989-08-29 Sterling Drug Inc. Dihydro-oxazolyl substituted-phenyl-aliphatic lower alkyl and their use as antiviral agents
US4675385A (en) * 1985-03-27 1987-06-23 Alpha Therapeutic Corporation Isolation of human plasma procoagulant protein factor VIII from biological factors
US4661493A (en) * 1985-03-29 1987-04-28 Pfizer Inc. Tioconazole and related compounds for control of Herpes simplex virus
DE3511411A1 (de) * 1985-03-29 1986-10-02 Basf Ag, 6700 Ludwigshafen Verwendung von azolylmethyloxiranen zur bekaempfung von viralen erkrankungen
CA1280753C (en) * 1985-07-02 1991-02-26 Philip Michael Carabateas Process for preparing heterocyclic substituted- phenoxyalkyl isoxazoles and-furans
JPS6419023A (en) * 1987-04-21 1989-01-23 Green Cross Corp Heat treatment of fibrinogen and fibrinogen preparation
CA1329760C (en) * 1987-10-29 1994-05-24 Ted C. K. Lee Plasma and recombinant protein formulations in high ionic strength media
US5110907A (en) * 1989-08-01 1992-05-05 Alpha Therapeutic Corporation Factor viii complex purification using heparin affinity chromatography
ZA908935B (en) * 1989-11-13 1991-08-28 Merrell Dow Pharma Prevention of glycoprotein enveloped virus infectivity by pyridinyloxazole-2-ones
US5110910A (en) * 1991-03-25 1992-05-05 Miles Inc. Virucidal euglobulin precipitation
TW235963B (de) * 1992-01-16 1994-12-11 Shionogi & Co
US5288853A (en) * 1992-04-30 1994-02-22 Alpha Therapeutic Corporation Factor viii purification process
CA2099630A1 (en) * 1992-07-02 1994-01-03 Guy Dominic Diana Heterocyclyl-phenoxyalkyl-piperidinylpyridazines as antiviral agents
ATE198277T1 (de) * 1992-10-02 2001-01-15 Genetics Inst Zusammensetzung, welche den koagulationsfaktor viii beinhaltet; verfahren zu deren herstellung und die benutzung eines oberflächenaktiven stoffes als stabilisator

Also Published As

Publication number Publication date
JP3735137B2 (ja) 2006-01-18
DE69513226D1 (de) 1999-12-16
US5514781A (en) 1996-05-07
AU1477295A (en) 1995-10-19
CN1129139A (zh) 1996-08-21
AU687153B2 (en) 1998-02-19
DK0686694T3 (da) 2000-05-08
CA2144674A1 (en) 1995-10-12
EP0686694A1 (de) 1995-12-13
JPH08175908A (ja) 1996-07-09
SI0686694T1 (en) 2000-04-30
EP0686694B1 (de) 1999-11-10
CA2144674C (en) 2010-01-12
DE69513226T2 (de) 2000-04-13
ES2139769T3 (es) 2000-02-16
GR3032546T3 (en) 2000-05-31

Similar Documents

Publication Publication Date Title
ATE101650T1 (de) Aktivierung von gentechnologisch hergestellten, in prokaryonten exprimierten antikoerpern.
DE3853922D1 (de) Aminosäurederivate als Amphotere.
LV10178A (lv) Fiziologiski saderigu glabajot stabilu cilveka olbaltumvielu preparatu iegusanas panemiens
EP0731712A4 (de) Physiologisch stabile butlersäurepräparate, und butlersäuresalze und -derivate als antineoplastische wirkstoff
DE69810481D1 (de) Stabilisierte antikörperformulierung
DE69511860D1 (de) Modifizierung von clostridium-toxinen und ihre anwendung als transport proteine
LU91342I2 (fr) Byetta-exénatide
DE3774274D1 (de) Solubilisierung von proteinen fuer pharmazeutsche zusammensetzungen.
ATE153648T1 (de) Verwendungen von alpha-hydroxyfettsäuren
BR9006835A (pt) Agentes de controle biologico aperfeicoado de insetos,e metodos de uso
ES2121479T3 (es) Solucion estabilizadora para proteinas y peptidos.
ATE273031T1 (de) Aminobiguanide und ihre verwendung zur desinfektion von kontaktlinsen und konservierung von pharmazeutischen zubereitungen
DE69513226D1 (de) Verwendung von Azolen als Virustötende Substanzen in Lösungen von biologisch aktiven Proteinen
NO981864L (no) Oppl°sningsmetoder
FI871522A0 (fi) Menetelmä proteiinien renaturoimiseksi
DE69416764D1 (de) Verfahren zur Stabilisierung eines Kontaktlinsenpräparats
ATE269904T1 (de) Transport und expression eines hybriden oberflächenproteins an der oberfläche von grampositiven bakterien
DK109590A (da) Biologisk aktivt protein
DE69129747D1 (de) In lösung bringen von proteinen in aktiver form
DE69227805D1 (de) Verwendung von Tri-n-Butylphosphat bei niedrigem pH in Lösungen von biologisch aktiven Proteinen für eine verbesserte viruzide Wirkung
DE59508900D1 (de) Verwendung von Dibrom-thiophen-carbonsäure-Derivaten als Mikrobizide
DK0512087T3 (da) Fremgangsmåde til reaktivering af denaturerede proteiner
NO2006006I1 (no) Aktivert protein C
ATE193524T1 (de) N-sulfonyl-und n-sulfinylaminosäurederivate als mikrobiozide
ES2060057T3 (es) Soluciones acuosas conteniendo proteina.

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
RZN Patent revoked