ATE186741T1 - Polyarylate, die derivate der natürlichen aminosäure l-tyrosin enthalten - Google Patents
Polyarylate, die derivate der natürlichen aminosäure l-tyrosin enthaltenInfo
- Publication number
- ATE186741T1 ATE186741T1 AT93920079T AT93920079T ATE186741T1 AT E186741 T1 ATE186741 T1 AT E186741T1 AT 93920079 T AT93920079 T AT 93920079T AT 93920079 T AT93920079 T AT 93920079T AT E186741 T1 ATE186741 T1 AT E186741T1
- Authority
- AT
- Austria
- Prior art keywords
- amino acid
- natural amino
- tyrosine
- containing derivatives
- polyarylate containing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G64/00—Macromolecular compounds obtained by reactions forming a carbonic ester link in the main chain of the macromolecule
- C08G64/04—Aromatic polycarbonates
- C08G64/06—Aromatic polycarbonates not containing aliphatic unsaturation
- C08G64/08—Aromatic polycarbonates not containing aliphatic unsaturation containing atoms other than carbon, hydrogen or oxygen
- C08G64/12—Aromatic polycarbonates not containing aliphatic unsaturation containing atoms other than carbon, hydrogen or oxygen containing nitrogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
- A61K9/204—Polyesters, e.g. poly(lactide-co-glycolide)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/32—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
- C07C235/34—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/20—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/22—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
- C08G63/68—Polyesters containing atoms other than carbon, hydrogen and oxygen
- C08G63/685—Polyesters containing atoms other than carbon, hydrogen and oxygen containing nitrogen
- C08G63/6854—Polyesters containing atoms other than carbon, hydrogen and oxygen containing nitrogen derived from polycarboxylic acids and polyhydroxy compounds
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G69/00—Macromolecular compounds obtained by reactions forming a carboxylic amide link in the main chain of the macromolecule
- C08G69/44—Polyester-amides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Polymers & Plastics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Polyesters Or Polycarbonates (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicinal Preparation (AREA)
- Polyamides (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Materials For Medical Uses (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/930,146 US5216115A (en) | 1990-06-12 | 1992-08-13 | Polyarylate containing derivatives of the natural amino acid L-tyrosine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE186741T1 true ATE186741T1 (de) | 1999-12-15 |
Family
ID=25458979
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT93920079T ATE186741T1 (de) | 1992-08-13 | 1993-08-13 | Polyarylate, die derivate der natürlichen aminosäure l-tyrosin enthalten |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US5216115A (de) |
| EP (1) | EP0656026B1 (de) |
| JP (1) | JP3255365B2 (de) |
| AT (1) | ATE186741T1 (de) |
| AU (1) | AU670821B2 (de) |
| CA (1) | CA2140255C (de) |
| DE (1) | DE69327057T2 (de) |
| WO (1) | WO1994004593A1 (de) |
Families Citing this family (87)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5587507A (en) * | 1995-03-31 | 1996-12-24 | Rutgers, The State University | Synthesis of tyrosine derived diphenol monomers |
| USRE37160E1 (en) * | 1990-06-12 | 2001-05-01 | Rutgers, The State University | Synthesis of tyrosine derived diphenol monomers |
| US5811447A (en) * | 1993-01-28 | 1998-09-22 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
| US6515009B1 (en) * | 1991-09-27 | 2003-02-04 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
| US5658995A (en) * | 1995-11-27 | 1997-08-19 | Rutgers, The State University | Copolymers of tyrosine-based polycarbonate and poly(alkylene oxide) |
| US6048521A (en) * | 1997-11-07 | 2000-04-11 | Rutgers, The State University | Copolymers of tyrosine-based polyarlates and poly(alkylene oxides) |
| US6120491A (en) * | 1997-11-07 | 2000-09-19 | The State University Rutgers | Biodegradable, anionic polymers derived from the amino acid L-tyrosine |
| DE69821600T2 (de) * | 1997-02-18 | 2005-01-05 | Rutgers, The State University | Von hydroxysäuren abgeleitete monomere und daraus hergestellte polymere |
| AU737151B2 (en) * | 1997-11-07 | 2001-08-09 | Rutgers, The State University | Radio-opaque polymeric biomaterials government license rights |
| US6602497B1 (en) | 1997-11-07 | 2003-08-05 | Rutgers, The State University | Strictly alternating poly(alkylene oxide ether) copolymers |
| US6623521B2 (en) | 1998-02-17 | 2003-09-23 | Md3, Inc. | Expandable stent with sliding and locking radial elements |
| JP4312384B2 (ja) | 1998-04-13 | 2009-08-12 | ラットガーズ ザ ステイト ユニヴァーシティ | コポリマーライブラリーの構築 |
| US20070233272A1 (en) * | 1999-02-23 | 2007-10-04 | Boyce Todd M | Shaped load-bearing osteoimplant and methods of making same |
| US8133421B2 (en) * | 1999-02-23 | 2012-03-13 | Warsaw Orthopedic, Inc. | Methods of making shaped load-bearing osteoimplant |
| DE69917339T2 (de) * | 1999-04-16 | 2005-05-12 | Rutgers, The State University | Poröse polymere stützgewebe für gewebetechnologie |
| US6103255A (en) | 1999-04-16 | 2000-08-15 | Rutgers, The State University | Porous polymer scaffolds for tissue engineering |
| US6899137B2 (en) * | 1999-06-28 | 2005-05-31 | California Institute Of Technology | Microfabricated elastomeric valve and pump systems |
| US20030170285A1 (en) * | 2001-11-13 | 2003-09-11 | Veazey William S. | Delivery of tissue engineering media |
| CA2822457C (en) | 2001-12-14 | 2016-03-08 | The University Of Wyoming | Methods and compositions for controlled resease of drugs |
| AU2003234231A1 (en) * | 2002-04-24 | 2003-11-10 | Rutgers | New polyarylates for drug delivery and tissue engineering |
| US20060182752A1 (en) * | 2003-05-15 | 2006-08-17 | Rutgers, The State University | Tri-block polymers for nanosphere-based drug or gene delivery |
| US8591951B2 (en) * | 2002-05-15 | 2013-11-26 | Joachim B. Kohn | Tri-block copolymers for nanosphere-based drug delivery |
| US6916868B2 (en) * | 2003-01-23 | 2005-07-12 | Integra Lifesciences Corporation | Selective modification of pendent functionalities of polymers |
| RU2373958C2 (ru) | 2003-09-25 | 2009-11-27 | Рутгерс, Дзе Стейт Юниверсити | Полимерные по существу рентгеноконтрастные продукты для эмболотерапии |
| US7368169B2 (en) * | 2003-12-01 | 2008-05-06 | Rutgers, The State University Of New Jersey | Hydrazide compounds with angiogenic activity |
| US7763065B2 (en) | 2004-07-21 | 2010-07-27 | Reva Medical, Inc. | Balloon expandable crush-recoverable stent device |
| US20060034891A1 (en) * | 2004-08-12 | 2006-02-16 | Laurie Lawin | Biodegradable controlled release bioactive agent delivery device |
| US20060034769A1 (en) * | 2004-08-13 | 2006-02-16 | Rutgers, The State University | Radiopaque polymeric stents |
| RU2396289C2 (ru) * | 2004-08-13 | 2010-08-10 | Рева Медикал, Инк. | Саморассасывающиеся рентгеноконтрастные по своей природе полимеры для многоцелевого использования |
| US8292944B2 (en) | 2004-12-17 | 2012-10-23 | Reva Medical, Inc. | Slide-and-lock stent |
| US7914574B2 (en) | 2005-08-02 | 2011-03-29 | Reva Medical, Inc. | Axially nested slide and lock expandable device |
| US9149378B2 (en) | 2005-08-02 | 2015-10-06 | Reva Medical, Inc. | Axially nested slide and lock expandable device |
| ES2718681T3 (es) | 2005-11-03 | 2019-07-03 | Tyrx Inc | Polímeros fenólicos resorbibles |
| US8287914B2 (en) | 2006-01-12 | 2012-10-16 | Rutgers, The State University Of New Jersey | Biomimetic hydroxyapatite synthesis |
| US8591531B2 (en) * | 2006-02-08 | 2013-11-26 | Tyrx, Inc. | Mesh pouches for implantable medical devices |
| US8315700B2 (en) * | 2006-02-08 | 2012-11-20 | Tyrx, Inc. | Preventing biofilm formation on implantable medical devices |
| MX2008010126A (es) | 2006-02-08 | 2010-02-22 | Tyrx Pharma Inc | Protesis de malla temporalmente rigidizadas. |
| WO2007115368A1 (en) * | 2006-04-07 | 2007-10-18 | The University Of Queensland | Porous polymer structures |
| WO2007115367A1 (en) * | 2006-04-07 | 2007-10-18 | The University Of Queensland | Porous polymer blend structures |
| AU2007340273B2 (en) | 2006-10-17 | 2012-08-30 | Rutgers, The State University Of New Jersey | N-substituted monomers and polymers |
| WO2010033640A1 (en) * | 2008-09-16 | 2010-03-25 | Rutgers, The State University Of New Jersey | Bioresorbable polymers synthesized from monomer analogs of natural metabolites |
| EP2079416A4 (de) * | 2006-10-30 | 2012-06-27 | Univ Rutgers | Elektrospinn-matrizen zur ausgabe hydrophiler und lipophiler verbindungen |
| AU2007351374B2 (en) | 2006-11-06 | 2012-11-08 | Medtronic, Inc. | Mesh pouches for implantable medical devices |
| US9023114B2 (en) * | 2006-11-06 | 2015-05-05 | Tyrx, Inc. | Resorbable pouches for implantable medical devices |
| ES2625134T3 (es) * | 2006-11-06 | 2017-07-18 | Tyrx, Inc. | Bolsas de mallas para dispositivos médicos implantables |
| CN101583380B (zh) * | 2006-11-30 | 2013-07-10 | 尼克塔治疗公司 | 用于制备聚合物轭合物的方法 |
| US7704275B2 (en) | 2007-01-26 | 2010-04-27 | Reva Medical, Inc. | Circumferentially nested expandable device |
| EP3542785A1 (de) | 2007-01-31 | 2019-09-25 | Rutgers, The State University of New Jersey | Gesteuerte freisetzung von wirkstoffen in der haut |
| AU2008232682B2 (en) | 2007-03-29 | 2013-03-21 | Medtronic, Inc. | Biodegradable, polymer coverings for breast implants |
| CA2686214C (en) * | 2007-05-02 | 2016-02-23 | Medtronic, Inc. | Dihydroxybenzoate polymers and uses thereof |
| EP2166981B1 (de) * | 2007-06-21 | 2016-09-07 | Tyrx, Inc. | Phenylester-seitenketten zur erhöhung der polymerresorbierbarkeit |
| EP2211773A4 (de) | 2007-11-30 | 2015-07-29 | Reva Medical Inc | Axial-radial verschachtelte expandierbare vorrichtung |
| EP2296579B1 (de) | 2008-06-02 | 2019-11-06 | Rutgers, the State University of New Jersey | Aus gewebe gezüchtetes ersatz-knorpelgewebe |
| WO2010006249A1 (en) * | 2008-07-10 | 2010-01-14 | Tyrx Pharma, Inc. | Sustained release formulations of psychoactive drugs |
| WO2010006046A1 (en) * | 2008-07-10 | 2010-01-14 | Tyrx Pharma, Inc. | Nsaid delivery from polyarylates |
| CA2833960C (en) | 2008-09-22 | 2015-12-22 | Medtronic, Inc. | Linear polyesteramides from aminophenolic esters |
| CN103948460B (zh) | 2008-10-10 | 2016-05-25 | 雷瓦医药公司 | 可扩展的滑动和锁定支架 |
| CA2737763C (en) | 2008-10-11 | 2019-04-09 | Rutgers, The State University Of New Jersey | Phase-separated biocompatible polymer compositions for medical uses |
| US20100215716A1 (en) * | 2009-02-23 | 2010-08-26 | Biomet Manufacturing Corp. | Compositions and methods for coating orthopedic implants |
| EP2437724B1 (de) | 2009-06-01 | 2015-09-30 | Tyrx, Inc. | Zusammensetzungen und verfahren zur verhinderung von wundinfektionen im brustbein |
| US9839628B2 (en) | 2009-06-01 | 2017-12-12 | Tyrx, Inc. | Compositions and methods for preventing sternal wound infections |
| JP5956337B2 (ja) | 2009-07-31 | 2016-07-27 | ラトガース,ザ ステート ユニバーシティ オブ ニュー ジャージー | 天然代謝産物のモノマー類似体から合成された生体吸収性ポリマー |
| US8409279B2 (en) | 2009-10-01 | 2013-04-02 | Lipose Corporation | Breast implant implantation method and apparatus |
| WO2011044567A1 (en) | 2009-10-11 | 2011-04-14 | Rutgers, The State University Of New Jersey | Biocompatible polymers for medial devices |
| JP5809237B2 (ja) | 2010-04-10 | 2015-11-10 | レヴァ メディカル、 インコーポレイテッドReva Medical, Inc. | 拡張可能なスライドロックステント |
| AU2011293344B2 (en) | 2010-08-25 | 2015-07-30 | Medtronic, Inc. | Novel medical device coatings |
| US8883861B2 (en) | 2010-11-01 | 2014-11-11 | Rutgers, The State University Of New Jersey | Iminic monomers and polymers thereof |
| AU2011326417A1 (en) | 2010-11-12 | 2013-05-09 | Tyrx, Inc. | Anchorage devices comprising an active pharmaceutical ingredient |
| US8961948B2 (en) | 2011-01-17 | 2015-02-24 | Rutgers, The State University Of New Jersey | Molecular surface design of tyrosine-derived polycarbonates for attachment of biomolecules |
| EP2734248B1 (de) | 2011-07-20 | 2018-10-17 | Tyrx, Inc. | Wirkstofffreisetzendes netz zur verhinderung der infektion eindringender transdermaler vorrichtungen |
| US11472918B2 (en) | 2012-02-03 | 2022-10-18 | Rutgers, The State University Of New Jersey | Polymeric biomaterials derived from phenolic monomers and their medical uses |
| CA3069030C (en) | 2012-02-03 | 2021-11-16 | Rutgers, The State University Of New Jersey | Polymeric biomaterials derived from phenolic monomers and their medical uses |
| KR101417305B1 (ko) | 2012-07-23 | 2014-07-08 | 포항공과대학교 산학협력단 | 이온성 액체가 화학적으로 결합된 고분자 전해질막 및 이를 이용한 연료전지 |
| WO2014137454A1 (en) | 2013-03-07 | 2014-09-12 | Tyrx, Inc. | Methods and compositions to inhibit the assemblage of microbial cells irreversibly associated with surfaces of medical devices |
| NZ711392A (en) | 2013-03-08 | 2020-05-29 | Polyactiva Pty Ltd | Polymer conjugate for delivery of a bioactive agent |
| WO2014159337A1 (en) | 2013-03-14 | 2014-10-02 | Reva Medical, Inc. | Reduced - profile slide and lock stent |
| EP3030265B1 (de) | 2013-08-07 | 2021-11-17 | Rutgers, The State University of New Jersey | Polymere biomaterialien aus monomeren mit hydroxysäuren und phenolverbindungen sowie deren medizinische verwendungen |
| CN105431178A (zh) | 2013-11-08 | 2016-03-23 | 泰尔克斯公司 | 用于防止手术切口部位感染的抗微生物组合物及方法 |
| AU2015370426B2 (en) | 2014-12-23 | 2019-09-12 | Rutgers, The State University Of New Jersey | Biocompatible iodinated diphenol monomers and polymers |
| US10774030B2 (en) | 2014-12-23 | 2020-09-15 | Rutgers, The State University Of New Jersey | Polymeric biomaterials derived from phenolic monomers and their medical uses |
| JP6974916B2 (ja) | 2015-02-27 | 2021-12-01 | ユニバーシティ オブ ピッツバーグ − オブ ザ コモンウェルス システム オブ ハイヤー エデュケイション | 多弁尖の弁の電気紡績ステントレス製作のための二重構成要素マンドレル |
| US11116640B2 (en) | 2017-02-13 | 2021-09-14 | Rutgers, The State University Of New Jersey | Polymer filament reinforced scaffold for partial meniscus regeneration |
| WO2018156856A1 (en) | 2017-02-23 | 2018-08-30 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Stentless biopolymer heart valve replacement capable of living tissue regeneration |
| WO2018175234A1 (en) | 2017-03-20 | 2018-09-27 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Mandrel-less electrospinning processing method and system, and uses therefor |
| WO2019094734A1 (en) | 2017-11-09 | 2019-05-16 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Decellularization and functionalization of extracellular matrix biomaterials |
| WO2021011639A1 (en) | 2019-07-15 | 2021-01-21 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Processing method and apparatus for micro-structured rope-like material |
| WO2024073481A2 (en) | 2022-09-28 | 2024-04-04 | Rutgers, The State University Of New Jersey | Microdevices for use in cell seeding onto two- and three-dimensional biocompatible constructs |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2891929A (en) * | 1954-03-31 | 1959-06-23 | Eastman Kodak Co | Polyesters of a glycol, a dicarboxylic acid and an aminoacid |
| NL295096A (de) * | 1962-07-09 | |||
| BE689347A (de) * | 1965-12-09 | 1967-04-14 | Madan Ag | |
| US4356166A (en) * | 1978-12-08 | 1982-10-26 | University Of Utah | Time-release chemical delivery system |
| MX158102A (es) * | 1980-03-24 | 1989-01-09 | Sun Chemical Corp | Procedimiento mejorado para la obtencion de una resina de eteres de poliamida |
| US4579866A (en) * | 1984-05-29 | 1986-04-01 | Usv Pharmaceutical Corp. | Phenylacetamides as anti-allergy, anti-asthma and anti-inflammatory agents |
| US4868277A (en) * | 1988-08-18 | 1989-09-19 | The Dow Chemical Company | Polyamide resins with good toughness properties |
| US4999417A (en) * | 1989-03-30 | 1991-03-12 | Nova Pharmaceutical Corporation | Biodegradable polymer compositions |
| FR2649713B1 (fr) * | 1989-07-12 | 1991-10-18 | Atochem | Copolyesteramides semialiphatiques thermotropes et leur procede de preparation |
| US5015476A (en) * | 1989-08-11 | 1991-05-14 | Paravax, Inc. | Immunization implant and method |
| US5099060A (en) | 1990-06-12 | 1992-03-24 | Rutgers, The State University Of New Jersey | Synthesis of amino acid-derived bioerodible polymers |
-
1992
- 1992-08-13 US US07/930,146 patent/US5216115A/en not_active Expired - Lifetime
-
1993
- 1993-08-13 DE DE69327057T patent/DE69327057T2/de not_active Expired - Lifetime
- 1993-08-13 AU AU50132/93A patent/AU670821B2/en not_active Expired
- 1993-08-13 AT AT93920079T patent/ATE186741T1/de active
- 1993-08-13 JP JP50645394A patent/JP3255365B2/ja not_active Expired - Lifetime
- 1993-08-13 EP EP93920079A patent/EP0656026B1/de not_active Expired - Lifetime
- 1993-08-13 WO PCT/US1993/007676 patent/WO1994004593A1/en not_active Ceased
- 1993-08-13 CA CA002140255A patent/CA2140255C/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| WO1994004593A1 (en) | 1994-03-03 |
| EP0656026A1 (de) | 1995-06-07 |
| JP3255365B2 (ja) | 2002-02-12 |
| AU5013293A (en) | 1994-03-15 |
| CA2140255A1 (en) | 1994-03-03 |
| US5216115A (en) | 1993-06-01 |
| DE69327057D1 (de) | 1999-12-23 |
| AU670821B2 (en) | 1996-08-01 |
| JPH08500387A (ja) | 1996-01-16 |
| CA2140255C (en) | 1999-04-06 |
| EP0656026B1 (de) | 1999-11-17 |
| DE69327057T2 (de) | 2000-04-13 |
| EP0656026A4 (de) | 1996-01-10 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE186741T1 (de) | Polyarylate, die derivate der natürlichen aminosäure l-tyrosin enthalten | |
| ES2031806T3 (es) | Factor de permeabilidad vascular humano. | |
| ATE104348T1 (de) | O-glycosyliertes ifn-alpha. | |
| ATE217884T1 (de) | Pentapeptid-methylester, die menschliche krebs hemmen | |
| FI945912A0 (fi) | Proteinoidikantajat ja menetelmät niiden valmistamiseksi sekä niiden käyttö | |
| EP0518697A3 (en) | Collagen film for sustained delivery of proteins | |
| TR200103469T2 (tr) | Amiloidojenik hastalığının önlenmesi ve tedavisi | |
| DE69212879D1 (de) | Magensaftstabile pharmazeutische Formulierungen zur Oral Verbreichung von Gallensäuren | |
| FI964253A0 (fi) | Kollageenivalmiste vaikuttavien aineiden säädellyksi vapauttamiseksi | |
| DE68928993D1 (de) | Arzneimittelzubereitung | |
| DE69527049D1 (de) | Therapeutische verwendungen von bakterizide/permeabilitätserhöhende protein dimer produkte | |
| IT1244548B (it) | Derivati della 5-oxo-l-prolina e loro applicazioni farmaceutiche | |
| ES2193272T3 (es) | Conjugados peptidicos, su utilizacion como medicamento y composiciones que los contienen. | |
| ES2196187T3 (es) | Conjugados peptidicos derivados de las hormonas timicas, su utilizacion a titulo de medicamento y composiciones que los contienen. | |
| DE69106892D1 (de) | Probucol enthaltendes arzneimittel mit gesteigerter bioverfügbarkeit. | |
| ATE146673T1 (de) | Kosmetika und pharmazeutika enthaltend extensin | |
| ATE93527T1 (de) | Peptide und deren benutzung. | |
| BG103905A (en) | New bpc peptide salts with organoprotective activity, method for their preparation and application in medicine | |
| ATE133960T1 (de) | Peptide mit bradykinin-antagonistischer wirkung | |
| DE69525757D1 (de) | Ein wachstumshormon und leucin enthaltende pharmazeutische formulierung | |
| EP0490383A3 (en) | Peptides of the hiv-gag protein, their preparation and use | |
| IT8821046A0 (it) | Poliammide biodegradabile pellicole e prodotti ottenuti da detta poliammide e procedimento per lasua preparazione. | |
| FI924916A7 (fi) | Kehossa hajoavat polyesterit lääkkeen annostelemiseksi pitkällä aikavä lillä | |
| DE69029259D1 (de) | Polypeptid, dessen herstellung, und dieses polypeptid enthaltende pharmazeutische verbindungen und kosmetika | |
| SE9100284D0 (sv) | Novel peptide |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |