ES2193272T3 - Conjugados peptidicos, su utilizacion como medicamento y composiciones que los contienen. - Google Patents

Conjugados peptidicos, su utilizacion como medicamento y composiciones que los contienen.

Info

Publication number
ES2193272T3
ES2193272T3 ES96939131T ES96939131T ES2193272T3 ES 2193272 T3 ES2193272 T3 ES 2193272T3 ES 96939131 T ES96939131 T ES 96939131T ES 96939131 T ES96939131 T ES 96939131T ES 2193272 T3 ES2193272 T3 ES 2193272T3
Authority
ES
Spain
Prior art keywords
lys
lysine
conjugates
compositions
contain
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES96939131T
Other languages
English (en)
Inventor
D Hinterland Lucien Dussourd
Anne-Marie Pinel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institut Europeen de Biologie Cellulaire
Original Assignee
Institut Europeen de Biologie Cellulaire
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Institut Europeen de Biologie Cellulaire filed Critical Institut Europeen de Biologie Cellulaire
Application granted granted Critical
Publication of ES2193272T3 publication Critical patent/ES2193272T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4986—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with sulfur as the only hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0819—Tripeptides with the first amino acid being acidic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1019—Tetrapeptides with the first amino acid being basic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/57—Compounds covalently linked to a(n inert) carrier molecule, e.g. conjugates, pro-fragrances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Emergency Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)

Abstract

LA INVENCION SE REFIERE A LOS CONJUGADOS PEPTIDICOS QUE CONTIENEN UNA SECUENCIA DE AL MENOS 3 AMINOACIDOS ELEGIDOS ENTRE LYS-LYS-GLY, GLY-HIS-LYS Y GLU-HIS-LYS, EN LA CUAL "LYS" REPRESENTA LA LISINA O UN DERIVADO HALOGENADO DE LA LISINA O UN DERIVADO METILADO DE LA LISINA, EN PARTICULAR LA METIL LISINA Y LA DIHIDROBROMOMETIL LISINA; LOS AMINOACIDOS PUEDEN ENCONTRARSE EN LAS FORMAS D, L O DL; DICHA SECUENCIA ESTA CONJUGADA QUIMICAMENTE O FISICAMENTE CON AL MENOS UN COMPUESTO SELECCIONADO ENTRE LOS ACIDOS MONOCARBOXILICOS DE FORMULA GENERAL (Y): HOOC R, ASI COMO SUS DERIVADOS ALCOHOL, ALDEHIDO O AMIDA; LOS ACIDOS DICARBOXILICOS DE FORMULA GENERAL (II): HOOC - R 1 - COOH. SE REFIERE ASIMISMO A SU UTILIZACION COMO MEDICAMENTOS Y A LAS COMPOSICIONES FARMACEUTICAS O COSMETICAS QUE LOS CONTIENEN.
ES96939131T 1995-11-15 1996-11-15 Conjugados peptidicos, su utilizacion como medicamento y composiciones que los contienen. Expired - Lifetime ES2193272T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9513543A FR2741075B1 (fr) 1995-11-15 1995-11-15 Conjugues peptidiques, leur utilisation a titre de medicament et compositions les contenant

Publications (1)

Publication Number Publication Date
ES2193272T3 true ES2193272T3 (es) 2003-11-01

Family

ID=9484595

Family Applications (1)

Application Number Title Priority Date Filing Date
ES96939131T Expired - Lifetime ES2193272T3 (es) 1995-11-15 1996-11-15 Conjugados peptidicos, su utilizacion como medicamento y composiciones que los contienen.

Country Status (9)

Country Link
EP (1) EP0869969B1 (es)
JP (1) JP2000512613A (es)
AT (1) ATE235508T1 (es)
AU (1) AU7683196A (es)
CA (1) CA2237993A1 (es)
DE (1) DE69627019T2 (es)
ES (1) ES2193272T3 (es)
FR (1) FR2741075B1 (es)
WO (1) WO1997018235A1 (es)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7001992B2 (en) 1997-05-30 2006-02-21 Human Genome Sciences, Inc. Antibodies to secreted protein HEMCM42
PT1015477E (pt) * 1997-05-30 2010-12-28 Human Genome Sciences Inc 32 proteínas humanas segregadas
FR2802413B1 (fr) * 1999-12-17 2003-10-31 Sederma Sa Compositions cosmetiques ou dermopharmaceutiques contenant le tripeptide n-palmytoyl-gly-hys-lys, pour eliminer, reduire ou prevenir l'apparition de rides quelles qu'en soient la localisation et la cause
FR2810323B1 (fr) * 2000-06-16 2002-09-06 Shiseido Int France Utilisation cosmetique d'un lipopeptide
KR100753472B1 (ko) * 2002-03-15 2007-08-31 주식회사 엘지생활건강 사람 콜라겐 ⅰ형의 c-말단에서 유래된 펩타이드에tat 펩타이드가 결합된 융합 펩타이드, 이의 제조방법,및 이를 포함하는 피부주름개선 화장료 조성물
FR2857667B1 (fr) 2003-07-18 2007-07-13 Inst Europ Biolog Cellulaire Nouveaux conjugues peptidiques utiles dans le traitement preventif et curatif de l'alopecie
FR2857597B1 (fr) * 2003-07-18 2008-01-25 Inst Europeen Biolog Cellulair Utilisation de conjugues peptidiques pour la preparation de compositions destinees au traitement preventif et curatif de l'alopecie.
ES2355571T3 (es) 2004-03-26 2011-03-29 Dsm Ip Assets B.V. Conjugados de ácidos arilalquílicos con aminoácidos y péptidos para usos cosméticos.
FR2870244B1 (fr) * 2004-05-11 2011-01-07 Centre Nat Rech Scient Conjugues dipeptidiques antagonistes de l'alpha-msh
FR2913603A1 (fr) * 2007-03-15 2008-09-19 Michel Yvan Hocquaux Composition cosmetique destinee au soin de peaux agressees par un traitement esthetique tel qu'intervention chirurgicale,traitement lasers,dermabrasion,peeling.
US20100310484A1 (en) * 2007-06-29 2010-12-09 Innovactiv Inc. Novel peptides, use thereof in cosmetic and cosmeceutic applications, and compositions comprising same
CA2692190C (en) * 2007-06-29 2015-06-02 Innovactiv Inc. Novel compounds, use thereof in cosmetic and cosmeceutic applications, and compositions comprising same
PL2165698T3 (pl) 2008-09-18 2017-01-31 Universkin Kompozycja kosmetyczna przeznaczona do pielęgnacji uszkodzonej skóry
US7928067B2 (en) 2009-05-14 2011-04-19 Ischemix Llc Compositions and methods for treating ischemia and ischemia-reperfusion injury
DE102009055970B4 (de) * 2009-11-27 2014-04-17 Marcus Asam Kosmetische Wirkstoffzubereitung
ES2640474T3 (es) 2010-11-18 2017-11-03 Ischemix Llc Compuestos lipoílicos y su uso para el tratamiento de la lesión isquémica
FR2986528B1 (fr) * 2012-02-06 2015-12-04 Inst Europeen Biolog Cellulair Nouveaux peptides antivieillissement
EP3615023B1 (en) 2017-04-25 2023-06-21 Ischemix LLC Lipoyl-glu-ala for the treatment of neurodegenerative damage caused by traumatic brain injury

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5120831A (en) * 1985-02-08 1992-06-09 Procyte Corporation Metal-peptide compositions
US5118665A (en) * 1990-02-09 1992-06-02 Procyte Corporation Anti-oxidative and anti-inflammatory metal:peptide complexes and uses thereof
DE4127790A1 (de) * 1991-08-22 1993-02-25 Wank Anna Verwendung von oligopeptiden mit 2 bis 5 peptidbindungen fuer kosmetische zwecke und einige neue oligopeptid-metallkomplexe

Also Published As

Publication number Publication date
EP0869969B1 (fr) 2003-03-26
ATE235508T1 (de) 2003-04-15
WO1997018235A1 (fr) 1997-05-22
EP0869969A1 (fr) 1998-10-14
CA2237993A1 (fr) 1997-05-22
AU7683196A (en) 1997-06-05
JP2000512613A (ja) 2000-09-26
FR2741075A1 (fr) 1997-05-16
FR2741075B1 (fr) 1998-01-30
DE69627019D1 (de) 2003-04-30
DE69627019T2 (de) 2004-01-22

Similar Documents

Publication Publication Date Title
FR2741075B1 (fr) Conjugues peptidiques, leur utilisation a titre de medicament et compositions les contenant
ATE186741T1 (de) Polyarylate, die derivate der natürlichen aminosäure l-tyrosin enthalten
DE69535963D1 (de) LHRH antagonistische Peptide
ATE308998T1 (de) Langwirkende arzneistoffe und diese enthaltende arzneimittel
ES2196187T3 (es) Conjugados peptidicos derivados de las hormonas timicas, su utilizacion a titulo de medicamento y composiciones que los contienen.
ATE217884T1 (de) Pentapeptid-methylester, die menschliche krebs hemmen
EP0696208A4 (en) ORAL DELIVERY FORM AND METHOD
BR9611367A (pt) Formulação farmacêutic liofilizada estável
DK2016950T3 (da) Farmaceutisk sammensætning omfattende et exendin-4-peptid
EP0596024A4 (en) Lipid conjugates of therapeutic peptides and protease inhibitors.
TR199501669A1 (tr) Peptid ve proteinlerin aerosol formülasyonlari.
DE69635720D1 (de) Pharmazeutische Zusammensetzungen von Cyclosporine mit einer Polyethoxylierten hydroxy-fettsäure
DE69115476D1 (de) Arzneimittel
TR199802534T2 (xx) Leptin (OB Protein) fragmanlar�
IT1244548B (it) Derivati della 5-oxo-l-prolina e loro applicazioni farmaceutiche
DK31991D0 (da) Peptid og farmaceutisk praeparat indeholdende et saadant peptid
BG97123A (bg) Производни на човешка, стимулирана от жлъчните соли, липаза и фармацевтични състави на тяхна основа
NO902871L (no) Fremgangsmaate for innfoering av et peptid i cytosol.
DK0707473T3 (da) Orale farmaceutiske præparater omfattende et protein eller et peptid, et antistof og polymerkugler
AU2426592A (en) New ganglioside derivatives
TR199600583A2 (tr) Farmasötik aktiviteye sahip -amino asitlerin tolere edilebilirliginin arttirilmasi.
KR920703003A (ko) 혈관활성 바소토신 유도체
DE69433999D1 (de) Entzündungshemmende peptide
DE3882233D1 (de) Gefaessaktive peptide.
SE9101586D0 (sv) Modified thioredoxin and its use