ES2196187T3 - Conjugados peptidicos derivados de las hormonas timicas, su utilizacion a titulo de medicamento y composiciones que los contienen. - Google Patents
Conjugados peptidicos derivados de las hormonas timicas, su utilizacion a titulo de medicamento y composiciones que los contienen.Info
- Publication number
- ES2196187T3 ES2196187T3 ES96939132T ES96939132T ES2196187T3 ES 2196187 T3 ES2196187 T3 ES 2196187T3 ES 96939132 T ES96939132 T ES 96939132T ES 96939132 T ES96939132 T ES 96939132T ES 2196187 T3 ES2196187 T3 ES 2196187T3
- Authority
- ES
- Spain
- Prior art keywords
- compositions containing
- timic
- hormones
- medicinal product
- conjugates derived
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000000203 mixture Substances 0.000 title abstract 2
- 229940088597 hormone Drugs 0.000 title 1
- 239000005556 hormone Substances 0.000 title 1
- 229940126601 medicinal product Drugs 0.000 title 1
- 150000001413 amino acids Chemical class 0.000 abstract 2
- 108010003422 Circulating Thymic Factor Proteins 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical class CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- 150000001408 amides Chemical class 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000000562 conjugate Substances 0.000 abstract 1
- 150000001991 dicarboxylic acids Chemical class 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 125000002485 formyl group Chemical class [H]C(*)=O 0.000 abstract 1
- 150000002763 monocarboxylic acids Chemical class 0.000 abstract 1
- 239000000863 peptide conjugate Substances 0.000 abstract 1
- 239000000724 thymus hormone Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/362—Polycarboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4986—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with sulfur as the only hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q7/00—Preparations for affecting hair growth
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/66—Thymopoietins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
- C07K7/062—Serum thymic factor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/57—Compounds covalently linked to a(n inert) carrier molecule, e.g. conjugates, pro-fragrances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Medicinal Chemistry (AREA)
- Dermatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Genetics & Genomics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Emergency Medicine (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Endocrinology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Cosmetics (AREA)
Abstract
LA INVENCION SE REFIERE A CONJUGADOS PEPTIDICOS QUE COMPRENDEN UNA SECUENCIA DE AL MENOS 3 AMINOACIDOS DERIVADOS DE UNA HORMONA TIMICA SELECCIONADA ENTRE LA TIMULINA Y LA TIMOPOYETINA, PUDIENDO ENCONTRARSE LOS AMINOACIDOS INDEPENDIENTEMENTE EN FORMA D, L O DL. LA SECUENCIA ESTA QUIMICA O FISICAMENTE CONJUGADA CON AL MENOS UN COMPUESTO SELECCIONADO ENTRE LOS ACIDOS MONOCARBOXILICOS QUE PRESENTAN LA FORMULA GENERAL (I): HOOC R, ASI COMO DERIVADOS DE ALCOHOL, ALDEHIDO O AMIDA. LOS ACIDOS DICARBOXILICOS PRESENTAN LA FORMULA GENERAL (II): HOOC R 1 COOH. LA INVENCION SE REFIERE ASIMISMO AL USO DE ESTOS CONJUGADOS COMO MEDICAMENTOS Y A LAS COMPOSICIONES FARMACEUTICAS O COSMETOLOGICAS QUE LOS INCLUYEN.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9513544 | 1995-11-15 | ||
| FR9513544A FR2741076B1 (fr) | 1995-11-15 | 1995-11-15 | Conjugues peptidiques derives des hormones thymiques, leur utilisation a titre de medicament et compositions les contenant |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES2196187T3 true ES2196187T3 (es) | 2003-12-16 |
| ES2196187T7 ES2196187T7 (es) | 2009-11-05 |
Family
ID=9484596
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES96939132T Active ES2196187T7 (es) | 1995-11-15 | 1996-11-15 | Conjugados peptidicos derivados de las homonas timicas, su utilizacion a titulo de medicamento y composiciones que lo contienen. |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US6211155B1 (es) |
| EP (1) | EP0861266B3 (es) |
| JP (1) | JP2000500447A (es) |
| AT (1) | ATE238348T1 (es) |
| AU (1) | AU7683296A (es) |
| CA (1) | CA2237995C (es) |
| DE (2) | DE69627691D1 (es) |
| ES (1) | ES2196187T7 (es) |
| FR (1) | FR2741076B1 (es) |
| WO (1) | WO1997018239A1 (es) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6030948A (en) * | 1997-12-19 | 2000-02-29 | Mann; Morris A. | Hair regeneration compositions for treatment of alopecia and methods of application related thereto |
| US6462019B1 (en) * | 1998-07-10 | 2002-10-08 | Osteoscreen, Inc. | Inhibitors of proteasomal activity and production for stimulating bone growth |
| US6902721B1 (en) * | 1998-07-10 | 2005-06-07 | Osteoscreen, Inc. | Inhibitors of proteasomal activity for stimulating bone growth |
| AU766826B2 (en) * | 1998-07-30 | 2003-10-23 | Government of The United States of America, as represented by The Secretary Department of Health & Human Services, The National Institutes of Health, The | Thymosin beta4 promotes wound repair |
| US20070015698A1 (en) * | 1998-07-30 | 2007-01-18 | United States Of America As Represented By The Secretary Of Health | Treatment of skin, and wound repair, with thymosin beta 4 |
| FR2857667B1 (fr) * | 2003-07-18 | 2007-07-13 | Inst Europ Biolog Cellulaire | Nouveaux conjugues peptidiques utiles dans le traitement preventif et curatif de l'alopecie |
| FR2857597B1 (fr) * | 2003-07-18 | 2008-01-25 | Inst Europeen Biolog Cellulair | Utilisation de conjugues peptidiques pour la preparation de compositions destinees au traitement preventif et curatif de l'alopecie. |
| US20060142227A1 (en) * | 2003-10-14 | 2006-06-29 | Itschak Lamensdorf | Amphiphylic peptide-PNA conjugates for the delivery of PNA through the blood brain barrier |
| ES2355571T3 (es) | 2004-03-26 | 2011-03-29 | Dsm Ip Assets B.V. | Conjugados de ácidos arilalquílicos con aminoácidos y péptidos para usos cosméticos. |
| FR2899105B1 (fr) * | 2006-03-30 | 2012-07-27 | Soc Extraction Principes Actif | Composition cosmetique et/ou pharmaceutique comprenant comme ingredient actif, au moins un hydrolysat de proteines de poacees et utilisation de cet hydrolysat |
| CA2701420C (en) * | 2007-10-29 | 2016-02-09 | Helix Biomedix Inc. | Protective skin care tetrapeptides |
| WO2009068688A2 (en) * | 2007-11-30 | 2009-06-04 | Immundiagnostik Ag | Composition for treatment and prevention of hair loss and premature graying of hair |
| FR3042192B1 (fr) | 2015-10-09 | 2017-12-08 | Inst Europeen De Biologie Cellulaire | Peptides utiles dans le traitement preventif et curatif de l'alopecie |
| US20180228837A1 (en) * | 2017-02-15 | 2018-08-16 | Tanya Rhodes | Stable iodine solutions with medical applications |
| CU24626B1 (es) | 2019-12-26 | 2022-11-07 | Centro Nac De Biopreparados | Composición farmacéutica a base de proteínas con actividad neuroprotectora, inmunomoduladora, antiinflamatoria y antimicrobiana |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1126261A (en) * | 1977-05-25 | 1982-06-22 | Jean-Francois Bach | Polypeptides and processes for the synthesis thereof |
| NZ189101A (en) * | 1977-12-08 | 1984-07-06 | Ortho Pharma Corp | Polypeptides having the ability to induce differentiation of both th-1+ t-lymphocytes and bu-1+ b-lymphocytes;pharmaceutical compositions |
| JPS5852225A (ja) * | 1981-09-22 | 1983-03-28 | Mitsui Pharmaceut Inc | 脱髄疾患治療剤 |
| JPS6089499A (ja) * | 1983-10-21 | 1985-05-20 | Mitsui Pharmaceut Inc | ペプチド |
| US4629723A (en) * | 1984-06-27 | 1986-12-16 | Ortho Pharmaceutical Corporation | Potent thymopentin analogs |
-
1995
- 1995-11-15 FR FR9513544A patent/FR2741076B1/fr not_active Expired - Fee Related
-
1996
- 1996-11-15 JP JP9518639A patent/JP2000500447A/ja active Pending
- 1996-11-15 DE DE69627691A patent/DE69627691D1/de not_active Expired - Lifetime
- 1996-11-15 AT AT96939132T patent/ATE238348T1/de not_active IP Right Cessation
- 1996-11-15 EP EP96939132A patent/EP0861266B3/fr not_active Expired - Lifetime
- 1996-11-15 ES ES96939132T patent/ES2196187T7/es active Active
- 1996-11-15 DE DE69627691T patent/DE69627691T4/de not_active Expired - Lifetime
- 1996-11-15 AU AU76832/96A patent/AU7683296A/en not_active Abandoned
- 1996-11-15 WO PCT/FR1996/001812 patent/WO1997018239A1/fr not_active Ceased
- 1996-11-15 US US09/068,767 patent/US6211155B1/en not_active Expired - Lifetime
- 1996-11-15 CA CA2237995A patent/CA2237995C/fr not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| CA2237995A1 (fr) | 1997-05-22 |
| ATE238348T1 (de) | 2003-05-15 |
| DE69627691T4 (de) | 2009-10-08 |
| DE69627691T2 (de) | 2004-03-11 |
| WO1997018239A1 (fr) | 1997-05-22 |
| FR2741076A1 (fr) | 1997-05-16 |
| EP0861266B1 (fr) | 2003-04-23 |
| EP0861266A1 (fr) | 1998-09-02 |
| DE69627691D1 (de) | 2003-05-28 |
| JP2000500447A (ja) | 2000-01-18 |
| CA2237995C (fr) | 2011-08-09 |
| US6211155B1 (en) | 2001-04-03 |
| ES2196187T7 (es) | 2009-11-05 |
| EP0861266B3 (fr) | 2009-04-08 |
| AU7683296A (en) | 1997-06-05 |
| FR2741076B1 (fr) | 1998-01-30 |
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