ATE187648T1 - Zusammensetzungen enthaltend lipoprotein- associated-coagulation-inhibitor (laci) zur herstellung eines medikaments zur behandlung von akuten oder chronischen enzündungen - Google Patents
Zusammensetzungen enthaltend lipoprotein- associated-coagulation-inhibitor (laci) zur herstellung eines medikaments zur behandlung von akuten oder chronischen enzündungenInfo
- Publication number
- ATE187648T1 ATE187648T1 AT93910775T AT93910775T ATE187648T1 AT E187648 T1 ATE187648 T1 AT E187648T1 AT 93910775 T AT93910775 T AT 93910775T AT 93910775 T AT93910775 T AT 93910775T AT E187648 T1 ATE187648 T1 AT E187648T1
- Authority
- AT
- Austria
- Prior art keywords
- laci
- treatment
- medication
- acute
- producing
- Prior art date
Links
- 102100030951 Tissue factor pathway inhibitor Human genes 0.000 title abstract 5
- 108010013555 lipoprotein-associated coagulation inhibitor Proteins 0.000 title abstract 3
- 208000038016 acute inflammation Diseases 0.000 title 1
- 230000006022 acute inflammation Effects 0.000 title 1
- 208000037976 chronic inflammation Diseases 0.000 title 1
- 230000006020 chronic inflammation Effects 0.000 title 1
- 229940079593 drug Drugs 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 239000003112 inhibitor Substances 0.000 abstract 3
- 206010061218 Inflammation Diseases 0.000 abstract 2
- 206010040047 Sepsis Diseases 0.000 abstract 2
- 206010040070 Septic Shock Diseases 0.000 abstract 2
- 101710139626 Tissue factor pathway inhibitor Proteins 0.000 abstract 2
- 230000004054 inflammatory process Effects 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 230000036303 septic shock Effects 0.000 abstract 2
- 102000002262 Thromboplastin Human genes 0.000 abstract 1
- 108010000499 Thromboplastin Proteins 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
- A61K38/57—Protease inhibitors from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Communicable Diseases (AREA)
- Cardiology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Heart & Thoracic Surgery (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US89194792A | 1992-06-01 | 1992-06-01 | |
| US450593A | 1993-01-13 | 1993-01-13 | |
| PCT/US1993/003860 WO1993024143A1 (en) | 1992-06-01 | 1993-04-23 | A method for using lipoprotein associated coagulation inhibitor to treat sepsis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE187648T1 true ATE187648T1 (de) | 2000-01-15 |
Family
ID=26673093
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT93910775T ATE187648T1 (de) | 1992-06-01 | 1993-04-23 | Zusammensetzungen enthaltend lipoprotein- associated-coagulation-inhibitor (laci) zur herstellung eines medikaments zur behandlung von akuten oder chronischen enzündungen |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP0643585B1 (de) |
| JP (3) | JP3957740B2 (de) |
| AT (1) | ATE187648T1 (de) |
| CA (1) | CA2136953C (de) |
| DE (1) | DE69327314T2 (de) |
| DK (1) | DK0643585T3 (de) |
| ES (1) | ES2139658T3 (de) |
| GR (1) | GR3032779T3 (de) |
| PT (1) | PT643585E (de) |
| WO (1) | WO1993024143A1 (de) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5824644A (en) * | 1994-07-07 | 1998-10-20 | G. D. Searle & Co. | Method of attenuating arterial stenosis |
| US5648331A (en) * | 1994-08-26 | 1997-07-15 | G.D. Searle & Co. | Method of inhibiting tissue ischemia and reperfusion injury |
| US5914316A (en) * | 1994-12-16 | 1999-06-22 | Washington University | Method of inhibiting intimal hyperplasia |
| WO1996040224A1 (en) * | 1995-06-07 | 1996-12-19 | Chiron Corporation | Regulation of cytokine synthesis and release |
| US5772629A (en) * | 1995-10-23 | 1998-06-30 | Localmed, Inc. | Localized intravascular delivery of TFPI for inhibition of restenosis in recanalized blood vessels |
| US5981471A (en) * | 1997-02-06 | 1999-11-09 | Entremed, Inc. | Compositions and methods for inhibiting cellular proliferation |
| CA2360347C (en) | 1998-12-31 | 2013-05-07 | Chiron Corporation | Improved expression of hiv polypeptides and production of virus-like particles |
| AU2002228911A1 (en) * | 2000-11-08 | 2002-05-21 | The General Hospital Corporation | Methods for inhibiting pain |
| US6939716B2 (en) | 2001-09-19 | 2005-09-06 | Washington University | Method for detecting conditions indicative of sepsis |
| CA2463655A1 (en) * | 2001-10-15 | 2003-04-24 | Chiron Corporation | Treatment of severe pneumonia by administration of tissue factor pathway inhibitor (tfpi) |
| EP1654283B1 (de) | 2003-08-13 | 2011-07-13 | Novartis Vaccines and Diagnostics, Inc. | Verbessertes verfahren zur reinigung von tfpi und tfpi-analogen |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK408089D0 (da) * | 1989-08-18 | 1989-08-18 | Novo Nordisk As | Proteiner |
-
1993
- 1993-04-23 WO PCT/US1993/003860 patent/WO1993024143A1/en not_active Ceased
- 1993-04-23 ES ES93910775T patent/ES2139658T3/es not_active Expired - Lifetime
- 1993-04-23 CA CA002136953A patent/CA2136953C/en not_active Expired - Fee Related
- 1993-04-23 EP EP93910775A patent/EP0643585B1/de not_active Expired - Lifetime
- 1993-04-23 DE DE69327314T patent/DE69327314T2/de not_active Expired - Fee Related
- 1993-04-23 PT PT93910775T patent/PT643585E/pt unknown
- 1993-04-23 DK DK93910775T patent/DK0643585T3/da active
- 1993-04-23 JP JP50053094A patent/JP3957740B2/ja not_active Expired - Fee Related
- 1993-04-23 AT AT93910775T patent/ATE187648T1/de not_active IP Right Cessation
-
2000
- 2000-02-28 GR GR20000400481T patent/GR3032779T3/el not_active IP Right Cessation
-
2004
- 2004-04-20 JP JP2004124804A patent/JP2004210801A/ja not_active Withdrawn
-
2007
- 2007-03-02 JP JP2007053543A patent/JP2007137901A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| JP2004210801A (ja) | 2004-07-29 |
| GR3032779T3 (en) | 2000-06-30 |
| EP0643585B1 (de) | 1999-12-15 |
| CA2136953A1 (en) | 1993-12-09 |
| DE69327314T2 (de) | 2000-04-13 |
| PT643585E (pt) | 2000-05-31 |
| WO1993024143A1 (en) | 1993-12-09 |
| JP3957740B2 (ja) | 2007-08-15 |
| DK0643585T3 (da) | 2000-05-08 |
| CA2136953C (en) | 2006-10-31 |
| ES2139658T3 (es) | 2000-02-16 |
| EP0643585A1 (de) | 1995-03-22 |
| JPH07507300A (ja) | 1995-08-10 |
| JP2007137901A (ja) | 2007-06-07 |
| DE69327314D1 (de) | 2000-01-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |