ATE189264T1 - Chimärisches oligonukleotid und dessen verwendung zur herstellung von nukleinsäure-transkripten - Google Patents
Chimärisches oligonukleotid und dessen verwendung zur herstellung von nukleinsäure-transkriptenInfo
- Publication number
- ATE189264T1 ATE189264T1 AT95402150T AT95402150T ATE189264T1 AT E189264 T1 ATE189264 T1 AT E189264T1 AT 95402150 T AT95402150 T AT 95402150T AT 95402150 T AT95402150 T AT 95402150T AT E189264 T1 ATE189264 T1 AT E189264T1
- Authority
- AT
- Austria
- Prior art keywords
- oligonucleotide
- target
- sequence
- segment
- nucleic acid
- Prior art date
Links
- 108091034117 Oligonucleotide Proteins 0.000 title abstract 8
- 108020004707 nucleic acids Proteins 0.000 title abstract 2
- 150000007523 nucleic acids Chemical class 0.000 title abstract 2
- 102000039446 nucleic acids Human genes 0.000 title abstract 2
- 230000000694 effects Effects 0.000 abstract 4
- 102000004163 DNA-directed RNA polymerases Human genes 0.000 abstract 2
- 108090000626 DNA-directed RNA polymerases Proteins 0.000 abstract 2
- 230000003321 amplification Effects 0.000 abstract 2
- 230000000295 complement effect Effects 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 238000003199 nucleic acid amplification method Methods 0.000 abstract 2
- 102000016928 DNA-directed DNA polymerase Human genes 0.000 abstract 1
- 108010014303 DNA-directed DNA polymerase Proteins 0.000 abstract 1
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 102100034343 Integrase Human genes 0.000 abstract 1
- 101710203526 Integrase Proteins 0.000 abstract 1
- 125000004122 cyclic group Chemical group 0.000 abstract 1
- 238000013518 transcription Methods 0.000 abstract 1
- 230000035897 transcription Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6865—Promoter-based amplification, e.g. nucleic acid sequence amplification [NASBA], self-sustained sequence replication [3SR] or transcription-based amplification system [TAS]
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9411455A FR2724934B1 (fr) | 1994-09-26 | 1994-09-26 | Oligonucleotide chimere et son utilisation dans l'obtention de transcrits d'un acide nucleique |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE189264T1 true ATE189264T1 (de) | 2000-02-15 |
Family
ID=9467268
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT95402150T ATE189264T1 (de) | 1994-09-26 | 1995-09-26 | Chimärisches oligonukleotid und dessen verwendung zur herstellung von nukleinsäure-transkripten |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US5744308A (de) |
| EP (1) | EP0721988B1 (de) |
| AT (1) | ATE189264T1 (de) |
| CA (1) | CA2159064A1 (de) |
| DE (1) | DE69514773T2 (de) |
| DK (1) | DK0721988T3 (de) |
| ES (1) | ES2144110T3 (de) |
| FR (1) | FR2724934B1 (de) |
Families Citing this family (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6001610A (en) * | 1994-11-23 | 1999-12-14 | Roche Diagnostics, Gmbh | Method for the particularly sensitive detection of nucleic acids |
| FR2737223B1 (fr) * | 1995-07-24 | 1997-09-12 | Bio Merieux | Procede d'amplification de sequences d'acide nucleique par deplacement, a l'aide d'amorces chimeres |
| US5853990A (en) * | 1996-07-26 | 1998-12-29 | Edward E. Winger | Real time homogeneous nucleotide assay |
| US6537783B1 (en) | 1996-08-02 | 2003-03-25 | Bio Merieux | Prefunctionalized nucleotide and process for amplifying a sequence using a prefunctionalized nucleotide |
| KR100440044B1 (ko) * | 1998-02-27 | 2004-07-14 | 팸진 비.브이. | 핵산의 비특이적 증폭방법 |
| FR2780059B1 (fr) * | 1998-06-17 | 2002-10-11 | Bio Merieux | Procede de marquage d'un acide ribonucleique et fragments d'arn marques ainsi obtenus |
| US6232104B1 (en) | 1999-08-17 | 2001-05-15 | Dade Behring Inc. | Detection of differences in nucleic acids by inhibition of spontaneous DNA branch migration |
| US6677445B1 (en) | 1999-08-27 | 2004-01-13 | Chiron Corporation | Chimeric antisense oligonucleotides and cell transfecting formulations thereof |
| US6692918B2 (en) * | 1999-09-13 | 2004-02-17 | Nugen Technologies, Inc. | Methods and compositions for linear isothermal amplification of polynucleotide sequences |
| DK1218542T3 (da) | 1999-09-13 | 2004-08-02 | Nugen Technologies Inc | Fremgangsmåder og sammensætninger til lineær isotermisk amplifikation af polynukleotidsekvenser |
| US7846733B2 (en) * | 2000-06-26 | 2010-12-07 | Nugen Technologies, Inc. | Methods and compositions for transcription-based nucleic acid amplification |
| CA2412721A1 (en) * | 2000-06-26 | 2002-01-03 | Nugen Technologies, Inc. | Methods and compositions for transcription-based nucleic acid amplification |
| AU2001295531A1 (en) * | 2000-09-02 | 2002-03-13 | Grünenthal GmbH | Antisense oligonucleotides against vanilloid receptor 1 |
| WO2002048401A2 (en) | 2000-12-11 | 2002-06-20 | Alexion Pharmaceuticals, Inc. | Nested oligonucleotides containing hairpin for nucleic acid amplification |
| CA2430329A1 (en) * | 2000-12-13 | 2002-06-20 | Nugen Technologies, Inc. | Methods and compositions for generation of multiple copies of nucleic acid sequences and methods of detection thereof |
| US7094536B2 (en) | 2001-03-09 | 2006-08-22 | Nugen Technologies, Inc. | Methods and compositions for amplification of RNA sequences |
| MXPA02012739A (es) * | 2001-03-09 | 2004-04-20 | Nugen Technologies Inc | Metodos y composiciones para amplificacion de secuencias de arn. |
| EA006066B1 (ru) * | 2001-08-20 | 2005-08-25 | Такара Био Инк. | Способы амплификации нуклеиновых кислот |
| US7414111B2 (en) * | 2001-09-19 | 2008-08-19 | Alexion Pharmaceuticals, Inc. | Engineered templates and their use in single primer amplification |
| CA2460639C (en) * | 2001-09-19 | 2013-07-16 | Alexion Pharmaceuticals, Inc. | Engineered templates and their use in single primer amplification |
| US20040054162A1 (en) * | 2001-10-30 | 2004-03-18 | Hanna Michelle M. | Molecular detection systems utilizing reiterative oligonucleotide synthesis |
| US7045319B2 (en) * | 2001-10-30 | 2006-05-16 | Ribomed Biotechnologies, Inc. | Molecular detection systems utilizing reiterative oligonucleotide synthesis |
| JP2005519621A (ja) * | 2002-03-11 | 2005-07-07 | ニューゲン テクノロジーズ, インコーポレイテッド | 3’一本鎖部分を含む二本鎖dnaを生成する方法および組換えのためのこれらの複合体の使用 |
| GB0230238D0 (en) * | 2002-12-28 | 2003-02-05 | Fu Guoliang | Combined exponential and linear amplification |
| ATE319861T1 (de) * | 2002-10-30 | 2006-03-15 | Pamgene Bv | Verbesserte methoden zur erzeugung einer vielzahl von rna-kopien |
| WO2004048594A2 (en) | 2002-11-21 | 2004-06-10 | Epicentre Technologies | Preparation and use of single-stranded transcription substrates for synthesis of transcription products corresponding to target sequences |
| US20060141467A1 (en) * | 2002-12-20 | 2006-06-29 | Q-Rna, Inc. | Methods and kits for making double stranded ribonucleic acids |
| US7402386B2 (en) | 2003-04-14 | 2008-07-22 | Nugen Technologies, Inc. | Global amplification using random priming by a composite primer |
| KR20070012779A (ko) * | 2003-10-29 | 2007-01-29 | 리보메드 바이오테그놀로지스 인코포레이티드 | 반복적 올리고뉴클레오티드 합성을 위한 조성물, 방법 및검출 기법 |
| CA2621267A1 (en) * | 2005-09-07 | 2007-03-15 | Nugen Technologies, Inc. | Improved nucleic acid amplification procedure |
| EP1921156A1 (de) * | 2006-11-10 | 2008-05-14 | bioMerieux B.V. | Verbesserte multiplexe Nukleinsäureamplifikation mittels blockierter Primer |
| US8034568B2 (en) * | 2008-02-12 | 2011-10-11 | Nugen Technologies, Inc. | Isothermal nucleic acid amplification methods and compositions |
| WO2009117698A2 (en) | 2008-03-21 | 2009-09-24 | Nugen Technologies, Inc. | Methods of rna amplification in the presence of dna |
| US10227641B2 (en) | 2008-04-30 | 2019-03-12 | Integrated Dna Technologies, Inc. | RNase H-based assays utilizing modified RNA monomers |
| EP2644708B1 (de) | 2008-04-30 | 2014-12-17 | Integrated Dna Technologies, Inc. | Rnase-h-basierte assays unter verwendung von modifizierten rna monomeren |
| US8911948B2 (en) * | 2008-04-30 | 2014-12-16 | Integrated Dna Technologies, Inc. | RNase H-based assays utilizing modified RNA monomers |
| EP2297346B1 (de) | 2008-05-15 | 2015-04-15 | Ribomed Biotechnologies, Inc. | VERFAHREN UND REAGENZIEN FÜR DEN NACHWEIS VON CpG-METHYLIERUNG MIT EINEM METHYL-CpG-BINDENDEN PROTEIN (MBP) |
| US8211644B2 (en) * | 2008-07-13 | 2012-07-03 | Ribomed Biotechnologies, Inc. | Molecular beacon-based methods for detection of targets using abscription |
| AU2010225937B2 (en) | 2009-03-15 | 2014-09-18 | Ribomed Biotechnologies, Inc. | Abscription based molecular detection |
| US20110117559A1 (en) * | 2009-11-13 | 2011-05-19 | Integrated Dna Technologies, Inc. | Small rna detection assays |
| WO2012135053A2 (en) | 2011-03-25 | 2012-10-04 | Integrated Dna Technologies, Inc. | Rnase h-based assays utilizing modified rna monomers |
| WO2013101783A2 (en) | 2011-12-30 | 2013-07-04 | Bio-Rad Laboratories, Inc. | Methods and compositions for performing nucleic acid amplification reactions |
| CA2892818A1 (en) | 2012-11-28 | 2014-06-05 | Abwiz Bio, Inc. | Preparation of gene-specific templates for the use in single primer amplification |
| CA2906365A1 (en) * | 2013-03-15 | 2014-09-18 | Integrated Dna Technologies, Inc. | Rnase h-based assays utilizing modified rna monomers |
| JP2022513124A (ja) * | 2018-11-21 | 2022-02-07 | アヴィダ バイオメッド, インコーポレイテッド | 標的化された核酸ライブラリー形成のための方法 |
| KR20230080464A (ko) * | 2020-10-02 | 2023-06-07 | 렉소겐 게엠베하 | 전사된 핵산을 생성하는 방법 및 수단 |
| EP3978626A1 (de) * | 2020-10-02 | 2022-04-06 | Lexogen GmbH | Verfahren und mittel zur erzeugung von transkribierten nukleinsäuren |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL86724A (en) * | 1987-06-19 | 1995-01-24 | Siska Diagnostics Inc | Methods and kits for amplification and testing of nucleic acid sequences |
| WO1989001050A1 (en) * | 1987-07-31 | 1989-02-09 | The Board Of Trustees Of The Leland Stanford Junior University | Selective amplification of target polynucleotide sequences |
| ATE92538T1 (de) * | 1988-01-21 | 1993-08-15 | Genentech Inc | Verstaerkung und nachweis von nukleinsaeuresequenzen. |
| CA1340807C (en) * | 1988-02-24 | 1999-11-02 | Lawrence T. Malek | Nucleic acid amplification process |
| US5130238A (en) * | 1988-06-24 | 1992-07-14 | Cangene Corporation | Enhanced nucleic acid amplification process |
| CA2001110A1 (en) * | 1988-11-18 | 1990-05-18 | Zvi G. Loewy | Compositions and process for amplifying and detecting nucleic acid sequences |
| CA2005589C (en) * | 1988-12-16 | 2001-02-06 | Akzo Nobel Nv | Self-sustained, sequence replication system |
| US5194370A (en) * | 1990-05-16 | 1993-03-16 | Life Technologies, Inc. | Promoter ligation activated transcription amplification of nucleic acid sequences |
| AU8997991A (en) * | 1991-01-31 | 1992-08-06 | Becton Dickinson & Company | Exonuclease mediated strand displacement amplification |
| US5169766A (en) * | 1991-06-14 | 1992-12-08 | Life Technologies, Inc. | Amplification of nucleic acid molecules |
| CA2141430C (en) * | 1992-08-04 | 2009-05-12 | Sherrol H. Mcdonough | Nucleic acid sequence amplification |
-
1994
- 1994-09-26 FR FR9411455A patent/FR2724934B1/fr not_active Expired - Fee Related
-
1995
- 1995-09-25 CA CA002159064A patent/CA2159064A1/fr not_active Abandoned
- 1995-09-26 DK DK95402150T patent/DK0721988T3/da active
- 1995-09-26 ES ES95402150T patent/ES2144110T3/es not_active Expired - Lifetime
- 1995-09-26 DE DE69514773T patent/DE69514773T2/de not_active Expired - Lifetime
- 1995-09-26 AT AT95402150T patent/ATE189264T1/de not_active IP Right Cessation
- 1995-09-26 US US08/533,912 patent/US5744308A/en not_active Expired - Lifetime
- 1995-09-26 EP EP95402150A patent/EP0721988B1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DK0721988T3 (da) | 2000-07-24 |
| ES2144110T3 (es) | 2000-06-01 |
| EP0721988A1 (de) | 1996-07-17 |
| US5744308A (en) | 1998-04-28 |
| FR2724934A1 (fr) | 1996-03-29 |
| CA2159064A1 (fr) | 1996-03-27 |
| DE69514773T2 (de) | 2000-09-07 |
| EP0721988B1 (de) | 2000-01-26 |
| FR2724934B1 (fr) | 1997-01-24 |
| DE69514773D1 (de) | 2000-03-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |