ATE189899T1 - Bioverträgliche zusammensetzungen - Google Patents

Bioverträgliche zusammensetzungen

Info

Publication number: ATE189899T1
Authority: AT; Austria
Prior art keywords: heparin; polymer; coated; methacrylate; biollar
Prior art date: 1996-11-20

Application number

AT97913308T

Other languages

English (en)

Inventor

Manuchehr Porssa

Paul Mathew Mcneillis

Richard Neil Templar Freeman

Original Assignee

Biocompatibles Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-11-20

Filing date

1997-11-20

Publication date

2000-03-15

1997-11-20 Application filed by Biocompatibles Ltd filed Critical Biocompatibles Ltd

2000-03-15 Application granted granted Critical

2000-03-15 Publication of ATE189899T1 publication Critical patent/ATE189899T1/de

Links

239000000203 mixture Substances 0.000 title 1
229920000642 polymer Polymers 0.000 abstract 4
HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 abstract 3
229920000669 heparin Polymers 0.000 abstract 3
229960002897 heparin Drugs 0.000 abstract 3
239000000178 monomer Substances 0.000 abstract 3
GYXOHPLRXDQGBP-UHFFFAOYSA-M 2-hydroxyethyl(trimethyl)azanium;2-methylprop-2-enoate Chemical compound CC(=C)C([O-])=O.C[N+](C)(C)CCO GYXOHPLRXDQGBP-UHFFFAOYSA-M 0.000 abstract 1
229920002683 Glycosaminoglycan Polymers 0.000 abstract 1
229910019142 PO4 Inorganic materials 0.000 abstract 1
239000008280 blood Substances 0.000 abstract 1
210000004369 blood Anatomy 0.000 abstract 1
125000002091 cationic group Chemical group 0.000 abstract 1
239000008199 coating composition Substances 0.000 abstract 1
GMSCBRSQMRDRCD-UHFFFAOYSA-N dodecyl 2-methylprop-2-enoate Chemical compound CCCCCCCCCCCCOC(=O)C(C)=C GMSCBRSQMRDRCD-UHFFFAOYSA-N 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
239000002607 heparin antagonist Substances 0.000 abstract 1
230000002209 hydrophobic effect Effects 0.000 abstract 1
239000007788 liquid Substances 0.000 abstract 1
NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 abstract 1
239000010452 phosphate Substances 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
239000000758 substrate Substances 0.000 abstract 1
229920001897 terpolymer Polymers 0.000 abstract 1
231100000331 toxic Toxicity 0.000 abstract 1
230000002588 toxic effect Effects 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L33/00—Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
- A61L33/0005—Use of materials characterised by their function or physical properties
- A61L33/0011—Anticoagulant, e.g. heparin, platelet aggregation inhibitor, fibrinolytic agent, other than enzymes, attached to the substrate
- A61L33/0029—Anticoagulant, e.g. heparin, platelet aggregation inhibitor, fibrinolytic agent, other than enzymes, attached to the substrate using an intermediate layer of polymer

Landscapes

Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
Hematology (AREA)
Surgery (AREA)
Epidemiology (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Materials Engineering (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Materials For Medical Uses (AREA)
Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
External Artificial Organs (AREA)
Treatment Of Liquids With Adsorbents In General (AREA)
Solid-Sorbent Or Filter-Aiding Compositions (AREA)
Manufacture Of Macromolecular Shaped Articles (AREA)

AT97913308T 1996-11-20 1997-11-20 Bioverträgliche zusammensetzungen ATE189899T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB9624130.2A GB9624130D0 (en)	1996-11-20	1996-11-20	Biocompatible compositions
PCT/GB1997/003189 WO1998022516A1 (en)	1996-11-20	1997-11-20	Biocompatible compositions

Publications (1)

Publication Number	Publication Date
ATE189899T1 true ATE189899T1 (de)	2000-03-15

Family

ID=10803229

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
AT97913308T ATE189899T1 (de)	1996-11-20	1997-11-20	Bioverträgliche zusammensetzungen
AT97913311T ATE215971T1 (de)	1996-11-20	1997-11-20	Anionenaustauschmaterialien und verfahren

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
AT97913311T ATE215971T1 (de)	1996-11-20	1997-11-20	Anionenaustauschmaterialien und verfahren

Country Status (11)

Country	Link
US (2)	US6432314B1 (de)
EP (2)	EP0939779B1 (de)
JP (2)	JP4051414B2 (de)
AT (2)	ATE189899T1 (de)
AU (3)	AU5061198A (de)
CA (1)	CA2271132C (de)
DE (2)	DE69711913T2 (de)
ES (1)	ES2143301T3 (de)
GB (1)	GB9624130D0 (de)
WO (3)	WO1998022516A1 (de)
ZA (3)	ZA9710467B (de)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6743878B2 (en)	1991-07-05	2004-06-01	Biocompatibles Uk Limited	Polymeric surface coatings
GB9522332D0 (en)	1995-11-01	1996-01-03	Biocompatibles Ltd	Braided stent
US6258371B1 (en) *	1998-04-03	2001-07-10	Medtronic Inc	Method for making biocompatible medical article
ATE406922T1 (de) *	1998-07-07	2008-09-15	Nof Corp	Zusammensetzung zur wundheilung, wundverband und verfahren zur behandlung vonwunden
WO2000035980A1 (en) *	1998-12-11	2000-06-22	Biocompatibles Limited	Crosslinked polymers and refractive devices formed therefrom
JP5140220B2 (ja) *	1999-05-27	2013-02-06	バイオコンパテイブルズ・ユーケイ・リミテツド	局所的な薬剤送達
ATE245667T1 (de) *	1999-05-27	2003-08-15	Biocompatibles Uk Ltd	Lösungen von polymeren
US6746686B2 (en)	2000-01-24	2004-06-08	Biocompatibles Uk Limited	Coated implants
AU2001292092A1 (en)	2000-10-06	2002-04-15	Biocompatibles Uk Limited	Zwitterionic polymers
GB0100761D0 (en)	2001-01-11	2001-02-21	Biocompatibles Ltd	Drug delivery from stents
DE60215635T2 (de) *	2001-04-26	2009-07-09	Nof Corp.	Inhibitoren zur Inhibierung unspezifischer Hybridisierung, klinische Diagnosereagenzien und ein Verfahren zur klinischen Analyse
US6844028B2 (en)	2001-06-26	2005-01-18	Accelr8 Technology Corporation	Functional surface coating
EP1480680B1 (de)	2002-03-07	2010-11-03	Biocompatibles UK Limited	Mit nucleinsäure complexierte block-copolymere
WO2005027991A1 (en) *	2003-09-19	2005-03-31	Cambridge University Technical Services Ltd	Orthopaedic devices
US20050208093A1 (en) *	2004-03-22	2005-09-22	Thierry Glauser	Phosphoryl choline coating compositions
JP2006238914A (ja) *	2005-02-28	2006-09-14	Hoya Corp	眼内レンズおよびその製造方法
WO2008006912A2 (en) *	2006-07-14	2008-01-17	Biocompatibles Uk Limited	Polymer
JP5557373B2 (ja)	2006-11-21	2014-07-23	アボットラボラトリーズ	薬剤溶出性コーティングにおけるテトラフルオロエチレン、ヘキサフルオロプロピレン、及びフッ化ビニリデンのターポリマーの使用
US20080286332A1 (en)	2007-05-14	2008-11-20	Pacetti Stephen D	Implantable medical devices with a topcoat layer of phosphoryl choline acrylate polymer for reduced thrombosis, and improved mechanical properties
JP5019524B2 (ja) *	2007-06-01	2012-09-05	国立大学法人東京大学	新規ポリ（メタ）アクリレート共重合体ならびに小胞体及びゴルジ体への送達方法
EP2352796A1 (de)	2008-12-05	2011-08-10	Semprus Biociences Corporation	Schichtförmige überzüge mit antifouling-, antimikrobiellen und antithrombogenen eigenschaften
AU2011264834B2 (en)	2010-06-09	2015-03-12	Semprus Biosciences Corp.	Non-fouling, anti-microbial, anti-thrombogenic graft-from compositions
CA2799786A1 (en)	2010-06-09	2011-12-15	Semprus Biosciences Corp.	Non-fouling, anti-microbial, anti-thrombogenic graft compositions
WO2012162789A1 (en)	2011-06-01	2012-12-06	University Of British Columbia	Polymers for reversing heparin-based anticoagulation
CA2859195C (en)	2011-12-14	2016-09-27	Semprus Biosciences Corp.	Imbibing process for contact lens surface modification
US9000063B2 (en)	2011-12-14	2015-04-07	Semprus Biosciences Corporation	Multistep UV process to create surface modified contact lenses
US9120119B2 (en)	2011-12-14	2015-09-01	Semprus Biosciences Corporation	Redox processes for contact lens modification
WO2013090790A1 (en)	2011-12-14	2013-06-20	Semprus Biosciences Corp.	Silicone hydrogel contact lens modified using lanthanide or transition metal oxidants
CA2858730C (en)	2011-12-14	2017-07-18	Semprus Biosciences Corp.	Surface modified contact lenses
CN103193927B (zh) *	2013-04-27	2016-01-20	南京构友生物材料有限公司	可键合的血液友好聚合物及其制法与用途
US10597540B2 (en) *	2013-05-27	2020-03-24	Jsr Corporation	Surface treatment agent for surface configured from inorganic material, tool and device having modified surface, and method for manufacturing tool and device
US10384167B2 (en)	2013-11-21	2019-08-20	Oasys Water LLC	Systems and methods for improving performance of osmotically driven membrane systems
JP6405387B2 (ja)	2014-10-02	2018-10-17	旭化成メディカル株式会社	生体由来液処理フィルター及びフィルターデバイス
KR20180076552A (ko)	2016-12-28	2018-07-06	주식회사 엘지화학	친수성 코팅 조성물
SG11202112411SA (en) *	2019-05-10	2021-12-30	Tufts College	Zwitterionic charged copolymer membranes
WO2022251491A1 (en)	2021-05-27	2022-12-01	Metro International Biotech, Llc	Crystalline solids of nicotinic acid mononucleotide and esters thereof and methods of making and use
CN113476661B (zh) *	2021-07-05	2022-08-05	中国医学科学院生物医学工程研究所	一种三层结构复合型自愈合人造血管及其制备方法

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SE306597B (de)	1964-12-17	1968-12-02	Incentive Ab
US3861948A (en) *	1972-05-22	1975-01-21	Kendall & Co	Pressure sensitive adhesive tape
ZA733409B (en) *	1972-05-31	1974-05-29	Commw Scient Ind Res Org	A process of manufacturing ion-exchange resins
SE456347B (sv)	1982-02-09	1988-09-26	Ird Biomaterial Ab	Ytmodifierat fast substrat samt forfarande for framstellning derav
SE8200751L (sv)	1982-02-09	1983-08-10	Olle Larm	Forfarande for kovalent koppling for framstellning av konjugat och hervid erhallna produkter
US4517241A (en) *	1982-12-02	1985-05-14	Alpert Andrew J	Chromatographic support material
US4704324A (en) *	1985-04-03	1987-11-03	The Dow Chemical Company	Semi-permeable membranes prepared via reaction of cationic groups with nucleophilic groups
US4865870A (en)	1988-07-07	1989-09-12	Becton, Dickinson And Company	Method for rendering a substrate surface antithrombogenic
JP2890316B2 (ja) *	1989-07-07	1999-05-10	科学技術振興事業団	生体適合性医療デバイス用材料
GB9023498D0 (en)	1990-10-29	1990-12-12	Biocompatibles Ltd	Soft contact lens material
US5075399A (en) *	1990-11-15	1991-12-24	Phillips Petroleum Company	Superabsorbent crosslinked ampholytic ion pair copolymers
WO1993001221A1 (en) *	1991-07-05	1993-01-21	Biocompatibles Limited	Polymeric surface coatings
WO1993014127A1 (en) *	1992-01-21	1993-07-22	University Of Utah	Method and composition for heparin binding using polyaminocations covalently immobilised on polymeric surfaces with polyethylene oxide spacers
US5556710A (en)	1992-04-24	1996-09-17	Biocompatibles Limited	Metal coating useful for rendering the surface of the metal biocompatible
US5342621A (en)	1992-09-15	1994-08-30	Advanced Cardiovascular Systems, Inc.	Antithrombogenic surface
GB9226791D0 (en) *	1992-12-23	1993-02-17	Biocompatibles Ltd	New materials
JPH07184989A (ja)	1993-12-28	1995-07-25	Kuraray Co Ltd	血液適合性医療用高分子材料および医療材料
JPH07285831A (ja) *	1994-04-18	1995-10-31	Mitsubishi Chem Corp	毛髪化粧料組成物

1996
- 1996-11-20 GB GBGB9624130.2A patent/GB9624130D0/en active Pending
1997
- 1997-11-20 ZA ZA9710467A patent/ZA9710467B/xx unknown
- 1997-11-20 EP EP97913311A patent/EP0939779B1/de not_active Expired - Lifetime
- 1997-11-20 ZA ZA9710468A patent/ZA9710468B/xx unknown
- 1997-11-20 AU AU50611/98A patent/AU5061198A/en not_active Abandoned
- 1997-11-20 AT AT97913308T patent/ATE189899T1/de not_active IP Right Cessation
- 1997-11-20 AU AU50610/98A patent/AU5061098A/en not_active Abandoned
- 1997-11-20 US US09/308,496 patent/US6432314B1/en not_active Expired - Lifetime
- 1997-11-20 ZA ZA9710466A patent/ZA9710466B/xx unknown
- 1997-11-20 DE DE69711913T patent/DE69711913T2/de not_active Expired - Lifetime
- 1997-11-20 WO PCT/GB1997/003189 patent/WO1998022516A1/en not_active Ceased
- 1997-11-20 ES ES97913308T patent/ES2143301T3/es not_active Expired - Lifetime
- 1997-11-20 WO PCT/GB1997/003192 patent/WO1998022517A1/en not_active Ceased
- 1997-11-20 WO PCT/GB1997/003191 patent/WO1998022162A1/en not_active Ceased
- 1997-11-20 AT AT97913311T patent/ATE215971T1/de not_active IP Right Cessation
- 1997-11-20 CA CA002271132A patent/CA2271132C/en not_active Expired - Fee Related
- 1997-11-20 JP JP52336498A patent/JP4051414B2/ja not_active Expired - Fee Related
- 1997-11-20 EP EP97913308A patent/EP0866815B1/de not_active Expired - Lifetime
- 1997-11-20 JP JP52336298A patent/JP4295359B2/ja not_active Expired - Lifetime
- 1997-11-20 US US09/117,729 patent/US6251964B1/en not_active Expired - Lifetime
- 1997-11-20 AU AU50608/98A patent/AU728887B2/en not_active Ceased
- 1997-11-20 DE DE69701319T patent/DE69701319T2/de not_active Expired - Lifetime

Also Published As

Publication number	Publication date
DE69701319D1 (de)	2000-03-30
AU728887B2 (en)	2001-01-18
CA2271132A1 (en)	1998-05-28
WO1998022162A1 (en)	1998-05-28
WO1998022517A1 (en)	1998-05-28
AU5060898A (en)	1998-06-10
JP2001506915A (ja)	2001-05-29
EP0866815B1 (de)	2000-02-23
JP4295359B2 (ja)	2009-07-15
ES2143301T3 (es)	2000-05-01
JP4051414B2 (ja)	2008-02-27
WO1998022516A1 (en)	1998-05-28
ZA9710468B (en)	1998-11-20
ZA9710467B (en)	1998-11-20
ATE215971T1 (de)	2002-04-15
DE69701319T2 (de)	2000-07-13
EP0866815A2 (de)	1998-09-30
AU5061098A (en)	1998-06-10
AU5061198A (en)	1998-06-10
ZA9710466B (en)	1998-11-20
EP0866815A3 (de)	1998-10-21
JP2001504877A (ja)	2001-04-10
DE69711913T2 (de)	2002-10-10
US6432314B1 (en)	2002-08-13
DE69711913D1 (de)	2002-05-16
EP0939779B1 (de)	2002-04-10
GB9624130D0 (en)	1997-01-08
EP0939779A1 (de)	1999-09-08
CA2271132C (en)	2007-04-17
US6251964B1 (en)	2001-06-26

Legal Events

Date	Code	Title	Description
2004-05-15	EEIH	Change in the person of patent owner
2006-08-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
ATE189899T1 (de)	2000-03-15	Bioverträgliche zusammensetzungen
BR0206885A (pt)	2004-08-10	Revestimentos de polìmeros de flúor coalescentes a baixas temperaturas
ATE167201T1 (de)	1998-06-15	Polymeroberflächenbeschichtungszusammensetzung
DE60005967D1 (de)	2003-11-20	Verwendung eines wasserlöslichen polymers in einer biociden zusammensetzung zur behandlung von harter oberfläche
BR9306246A (pt)	1998-06-30	Método para tratar um substrato metálico não-ferroso e substrato metálico não-ferroso
TR199700760T1 (xx)	1998-02-21	Nesnelerin hiyaluronik asit ile kaplanmas�.
DE69703105D1 (de)	2000-10-19	Zusammensetzung und verfahren zur behandlung von phosphatierten metalloberflächen
EA199900444A1 (ru)	1999-12-29	Способ предотвращения коррозии металлических листов при использовании винилсиланов
AU6412386A (en)	1987-04-30	Fluoroacrylic monomers, polymers derived therefrom and their application to the water-repellency and oil-repellency treatment of various substrates
BRPI0407625A (pt)	2006-02-21	composição para tratar superfìcies metálicas, camada passivadora sobre uma superfìcie metálica, superfìcie, processo para formar uma camada passivadora sobre uma superfìcie metálica, uso de uma composição, sistema em uma superfìcie metálica, e, processo para formar um sistema de revestimento
DE69230823D1 (de)	2000-04-27	Polymere oberflächenbeschichtungszusammensetzungen
PT1034224E (pt)	2005-04-29	Composicao de revestimento em po, biocida, a sua preparacao e utilizacao
DE69930155D1 (de)	2006-04-27	Spray verabreichung von zellen
ATE242296T1 (de)	2003-06-15	Beschichtung eines gegenstandes von belang
NO155843C (no)	1987-06-10	Fremgangsmaate ved polymerisering av vinylklorid med vesentlig eliminering av polymeroppbygging paa de indre overflater av polymerisasjonskaret.
EP1192932A3 (de)	2002-12-11	Dauerhaftes Haarfrisurgel
DE3375921D1 (en)	1988-04-14	Humidity resistant coatings employing branched polymers of t-butyl acrylate
RU95109183A (ru)	1997-04-10	Способ микродугового нанесения покрытия на поверхность изделия
DK0818479T3 (da)	2001-01-15	Polymere overfladecoatinger
ES476299A1 (es)	1979-11-16	Procedimiento de obtencion de dispersiones acuosas de poli- meros de adicion formadores de pelicula
ES8300834A1 (es)	1982-11-01	Un procedimiento mejorado para proteger superficies marinas contra el desarrollo de organismos
FR2762606B1 (fr)	1999-06-11	Systeme monocomposant a base de latex coreactifs conduisant a des revetements reticulables a temperature ambiante et post-reticulables par traitement thermique et leur application dans le domaine des revetements
TW200420689A (en)	2004-10-16	Masonry treating agent
KR900701939A (ko)	1990-12-05	스프레이 부스등에 일시적 차단층을 침착하기 위한 방법 및 용액
BRPI0415817A (pt)	2006-12-26	monÈmeros de acrilato perfluoroalquila-substituìdos e polìmeros dos mesmos