ATE189939T1 - Hochempfindlicher molekular identifikator - Google Patents

Hochempfindlicher molekular identifikator

Info

Publication number
ATE189939T1
ATE189939T1 AT94921778T AT94921778T ATE189939T1 AT E189939 T1 ATE189939 T1 AT E189939T1 AT 94921778 T AT94921778 T AT 94921778T AT 94921778 T AT94921778 T AT 94921778T AT E189939 T1 ATE189939 T1 AT E189939T1
Authority
AT
Austria
Prior art keywords
highly sensitive
molecular identifier
sensitive molecular
samples
directed
Prior art date
Application number
AT94921778T
Other languages
English (en)
Inventor
Kenneth H Purser
Reijer Koudijs
Marcel M Mulder
Frans W Saris
Original Assignee
High Voltage Eng Europ
Kenneth H Purser
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by High Voltage Eng Europ, Kenneth H Purser filed Critical High Voltage Eng Europ
Application granted granted Critical
Publication of ATE189939T1 publication Critical patent/ATE189939T1/de

Links

Classifications

    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J27/00—Ion beam tubes
    • H01J27/02—Ion sources; Ion guns
    • H01J27/028—Negative ion sources
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/004—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn
    • H01J49/0086—Accelerator mass spectrometers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/62—Detectors specially adapted therefor
    • G01N30/72—Mass spectrometers
    • G01N30/7206—Mass spectrometers interfaced to gas chromatograph
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/62—Detectors specially adapted therefor
    • G01N30/72—Mass spectrometers
    • G01N30/7233—Mass spectrometers interfaced to liquid or supercritical fluid chromatograph

Landscapes

  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Combustion & Propulsion (AREA)
  • Analytical Chemistry (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT94921778T 1993-07-30 1994-06-30 Hochempfindlicher molekular identifikator ATE189939T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/099,844 US5438194A (en) 1993-07-30 1993-07-30 Ultra-sensitive molecular identifier
PCT/IB1994/000236 WO1995004369A1 (en) 1993-07-30 1994-06-30 An ultra-sensitive molecular identifier

Publications (1)

Publication Number Publication Date
ATE189939T1 true ATE189939T1 (de) 2000-03-15

Family

ID=22276877

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94921778T ATE189939T1 (de) 1993-07-30 1994-06-30 Hochempfindlicher molekular identifikator

Country Status (6)

Country Link
US (1) US5438194A (de)
EP (1) EP0721655B1 (de)
JP (1) JPH09500967A (de)
AT (1) ATE189939T1 (de)
DE (1) DE69423109T2 (de)
WO (1) WO1995004369A1 (de)

Families Citing this family (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5621209A (en) * 1995-04-10 1997-04-15 High Voltage Engineering Europa B.V. Attomole detector
US5569915A (en) * 1995-04-14 1996-10-29 Purser; Kenneth H. Sensitive mass spectroscopy using molecular fragmentation
US5545894A (en) * 1995-05-04 1996-08-13 The Regents Of The University Of California Compact hydrogen/helium isotope mass spectrometer
US5616465A (en) 1995-08-09 1997-04-01 The Regents Of The University Of California Detection and isolation of nucleic acid sequences using competitive hybridization probes
WO1998036095A1 (en) * 1997-02-14 1998-08-20 George Washington University An assay for the measurement of dna synthesis rates
JP3801355B2 (ja) * 1998-07-16 2006-07-26 フロンティア・ラボ株式会社 未知試料検索方法、未知試料検索装置及び未知試料検索用記録媒体
AU2001286665A1 (en) * 2000-08-24 2002-03-04 Newton Scientific, Inc. Sample introduction interface for analytical processing
US7511246B2 (en) 2002-12-12 2009-03-31 Perkinelmer Las Inc. Induction device for generating a plasma
US8633416B2 (en) 2005-03-11 2014-01-21 Perkinelmer Health Sciences, Inc. Plasmas and methods of using them
US7742167B2 (en) 2005-06-17 2010-06-22 Perkinelmer Health Sciences, Inc. Optical emission device with boost device
US8622735B2 (en) * 2005-06-17 2014-01-07 Perkinelmer Health Sciences, Inc. Boost devices and methods of using them
US20070219521A1 (en) * 2006-03-17 2007-09-20 The Procter & Gamble Company Absorbent article comprising a synthetic polymer derived from a renewable resource and methods of producing said article
GB0714040D0 (en) 2007-07-19 2007-08-29 Xceleron Ltd Quantification of analytes
WO2010090324A1 (ja) 2009-02-06 2010-08-12 株式会社日本触媒 ポリアクリル酸（塩）系吸水性樹脂およびその製造方法
US8933131B2 (en) 2010-01-12 2015-01-13 The Procter & Gamble Company Intermediates and surfactants useful in household cleaning and personal care compositions, and methods of making the same
US20130043384A1 (en) 2010-04-26 2013-02-21 Nippon Shokubai Co., Ltd. Polyacrylic acid (salt), polyacrylic acid (salt)-based water-absorbing resin, and process for producing same
JP5764122B2 (ja) 2010-04-26 2015-08-12 株式会社日本触媒 ポリアクリル酸（塩）、ポリアクリル酸（塩）系吸水性樹脂及びその製造方法
US20120108692A1 (en) 2010-10-27 2012-05-03 John Collins Dyer Preparation of foam materials derived from renewable resources
US8083064B2 (en) 2011-01-25 2011-12-27 The Procter & Gamble Company Sustainable packaging for consumer products
MX2013009546A (es) 2011-02-17 2013-11-22 Procter & Gamble Alquilfenil sulfonatos lineales de base biologica.
WO2012138423A1 (en) 2011-02-17 2012-10-11 The Procter & Gamble Company Compositions comprising mixtures of c10-c13 alkylphenyl sulfonates
US20120288692A1 (en) 2011-04-12 2012-11-15 Norman Scott Broyles Renewably sourced films and methods of forming same
BR112014002859A2 (pt) 2011-08-10 2017-06-13 Metabolix Inc purificação pós-processamento para produção de gama-butiro lactona
US20130273384A1 (en) 2012-04-11 2013-10-17 The Procter & Gamble Company Poly(Acrylic Acid) From Bio-Based Acrylic Acid And Its Derivatives
US20130274520A1 (en) 2012-04-11 2013-10-17 The Procter & Gamble Company Purification Of Bio Based Acrylic Acid To Crude And Glacial Acrylic Acid
US20130270212A1 (en) 2012-04-16 2013-10-17 The Procter & Gamble Company Plastic Bottles For Perfume Compositions Having Improved Crazing Resistance
KR101741887B1 (ko) 2012-05-07 2017-05-30 더 프록터 앤드 갬블 캄파니 가요성 용기
CN104350034B (zh) 2012-06-08 2018-07-31 Cj 第一制糖株式会社 可再生丙烯酸生产和自其制备的产物
US9259798B2 (en) 2012-07-13 2016-02-16 Perkinelmer Health Sciences, Inc. Torches and methods of using them
CN104603021B (zh) 2012-08-06 2019-08-06 宝洁公司 制造柔性容器的方法
US9452422B2 (en) 2013-03-12 2016-09-27 The Procter & Gamble Company Catalysts and processes for the production of aromatic compounds from lignin
RU2615756C1 (ru) * 2013-07-09 2017-04-11 Феникс Нуклеа Лэбс Ллс Высоконадежный, с большим сроком службы источник отрицательно заряженных ионов
EP3148959B1 (de) 2014-05-30 2023-11-22 Novomer Inc. Integrierte verfahren zur chemischen analyse
MA41514A (fr) 2015-02-13 2017-12-19 Novomer Inc Procédés intégrés de synthèse chimique
EP3268342B1 (de) 2015-03-13 2020-02-19 The Procter and Gamble Company Herstellung von terephthalsäure durch reduktive kopplung von propiolsäure oder propiolsäurederivaten
CA2991207A1 (en) 2015-07-01 2017-01-05 Novomer, Inc. Methods for production of terephthalic acid from ethylene oxide
CA2991202A1 (en) 2015-07-01 2017-01-05 Novomer, Inc. Methods for coproduction of terephthalic acid and styrene from ethylene oxide
BR112018002143A2 (pt) 2015-07-31 2018-09-18 Novomer Inc sistema de produção/processo de produção para ácido acrílico e precursores do mesmo
US20180282251A1 (en) 2017-03-21 2018-10-04 Novomer, Inc. Systems and processes for producing organic acids direct from beta-lactones
US10662139B2 (en) 2016-03-21 2020-05-26 Novomer, Inc. Acrylic acid production process
EP3596156A4 (de) 2017-03-17 2020-12-30 Novomer, Inc. Polyamide und verfahren zur herstellung davon
US20190002385A1 (en) 2017-06-30 2019-01-03 Novomer, Inc. Compositions for improved production of acrylic acid
US10676426B2 (en) 2017-06-30 2020-06-09 Novomer, Inc. Acrylonitrile derivatives from epoxide and carbon monoxide reagents
US10590099B1 (en) 2017-08-10 2020-03-17 Novomer, Inc. Processes for producing beta-lactone with heterogenous catalysts
US10961209B2 (en) 2017-08-10 2021-03-30 Novomer, Inc. Processes for producing beta-lactone and beta-lactone derivatives with heterogenous catalysts
CN108226274A (zh) * 2018-01-26 2018-06-29 中国科学院地球环境研究所 14c-ams快速在线分析仪
EP3768742A4 (de) 2018-03-22 2022-04-06 Novomer, Inc. Schwefel- und phosphorhaltige polymere und verfahren zu deren herstellung
EP3774987B1 (de) 2018-04-06 2024-06-05 Novomer, Inc. Verfahren zur herstellung eines films enthaltend polypropiolacton, und danach hergestellter film
EP3814005B1 (de) 2018-06-29 2024-04-17 Novomer, Inc. Systeme und verfahren zur herstellung von organischen säuren direkt aus beta-lactonen
JP7676023B2 (ja) 2018-07-13 2025-05-14 ノボマー， インコーポレイテッド ポリラクトン発泡体及びその製造方法
US11180609B2 (en) 2018-08-02 2021-11-23 Saudi Aramco Technologies Company Sustainable polymer compositions and methods
KR20210137037A (ko) 2019-03-08 2021-11-17 노보머, 인코포레이티드 아미드 및 니트릴 화합물을 생산하기 위한 통합 방법 및 시스템
JP2022543388A (ja) 2019-08-02 2022-10-12 ノボマー， インコーポレイテッド 不均一触媒及びその用途
JP7687690B2 (ja) * 2022-02-16 2025-06-03 国立研究開発法人日本原子力研究開発機構 負イオン源及び負イオン生成方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3617789A (en) * 1969-04-14 1971-11-02 Univ Pennsylvania Process for production of negative helium ions and other negative ions
US3786249A (en) * 1971-12-20 1974-01-15 Stanford Research Inst Negative ion duoplasmatron mass spectrometer for isotope ratio analysis
US4037100A (en) * 1976-03-01 1977-07-19 General Ionex Corporation Ultra-sensitive spectrometer for making mass and elemental analyses

Also Published As

Publication number Publication date
DE69423109T2 (de) 2000-09-28
US5438194A (en) 1995-08-01
WO1995004369A1 (en) 1995-02-09
DE69423109D1 (de) 2000-03-30
EP0721655A4 (de) 1997-04-02
EP0721655B1 (de) 2000-02-23
EP0721655A1 (de) 1996-07-17
JPH09500967A (ja) 1997-01-28

Similar Documents

Publication Publication Date Title
DE69423109D1 (de) Hochempfindlicher molekular identifikator
SE9301270D0 (sv) Biosensor
DE69422248D1 (de) Gaschromatograph-Massenspektrometersystem mit Gettersorptionspumpe
DE69735445D1 (de) Abspaltbare, nicht-flüchtige moleküle zur massenmarkierung
DK0839006T4 (da) Fremgangsmåde til stabilisering af proteiner i et surt miljø med et højester-pectin
DE69317443D1 (de) Dateienumsetzungssystem
EA200000196A1 (ru) Универсальная плазма крови
NO970155L (no) Kunstig ekstracellulær biologisk matrise samt fremgangsmåte ved fremstilling derav
ES2162970T3 (es) Metodo y aparato para el control del funcionamiento de un decodificador de señal en un sistema de radiodifusion.
EP0247730A3 (de) Antikörper, ihre Herstellung sowie Verwendung und dieselben enthaltende Produkte
DE69631468D1 (de) Nachweiss von antikörper gegen bakterielle antigene durch fluoreszenz-polarisation
DE69637844D1 (de) Neues tgf-beta-ahnliches cytokin
WO2002017348A3 (en) Sample introduction interface for analytical processing of a sample placed on a substrate
TR199900780T2 (xx) Mikroorganizma teşhisi.
ES2132174T3 (es) Reactivo liquido de tromboplastina.
DK0809807T3 (da) Immunoassay til tælling af celler
DE69216258D1 (de) Gaschromatographisches System zur Analyse von Abgasen
DE69434384D1 (de) Metalkomplexbildner
ATE69108T1 (de) Elektrophoretisches gel hoher aufloesung sowie methode zur abscheidung von serumproteinen.
DK0659276T3 (da) Immunoassay til eftervisning af collagen eller collagenfragmenter
ATE318843T1 (de) Faktor g reduzierte amebozyten-lysate zur nachweisung der bakteriellen endotoxinen
ES2174276T3 (es) Enriquecimiento con oxigeno de combustion en sistemas de hornos de cemento.
AU4654296A (en) Gas concentration and injection system for chromatographic analysis of organic trace gases
EA199700196A1 (ru) Способ получения фактора ix из биологических источников и фактор ix, полученный этим способом
ATE194381T1 (de) Alkoholhaltige instant-getränkemischung, ihre herstellung und verwendung

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties