ATE190054T1 - Monohydrate von aminobenzensulfonsäurederivaten und verfahren zu ihrer herstellung - Google Patents
Monohydrate von aminobenzensulfonsäurederivaten und verfahren zu ihrer herstellungInfo
- Publication number
- ATE190054T1 ATE190054T1 AT96120136T AT96120136T ATE190054T1 AT E190054 T1 ATE190054 T1 AT E190054T1 AT 96120136 T AT96120136 T AT 96120136T AT 96120136 T AT96120136 T AT 96120136T AT E190054 T1 ATE190054 T1 AT E190054T1
- Authority
- AT
- Austria
- Prior art keywords
- monohydrates
- production
- acid derivatives
- monohydrate
- aminobenzenesulphonic acid
- Prior art date
Links
- 150000004682 monohydrates Chemical class 0.000 title abstract 3
- ZMCHBSMFKQYNKA-UHFFFAOYSA-N 2-aminobenzenesulfonic acid Chemical class NC1=CC=CC=C1S(O)(=O)=O ZMCHBSMFKQYNKA-UHFFFAOYSA-N 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- DCDFLGVJWQIRGH-UHFFFAOYSA-N 5-methyl-2-piperazin-4-ium-1-ylbenzenesulfonate Chemical compound OS(=O)(=O)C1=CC(C)=CC=C1N1CCNCC1 DCDFLGVJWQIRGH-UHFFFAOYSA-N 0.000 abstract 1
- 238000010521 absorption reaction Methods 0.000 abstract 1
- 208000019622 heart disease Diseases 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/08—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 not condensed with other rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP32664895 | 1995-12-15 | ||
| JP32706895 | 1995-12-15 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE190054T1 true ATE190054T1 (de) | 2000-03-15 |
Family
ID=26572248
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT96120136T ATE190054T1 (de) | 1995-12-15 | 1996-12-14 | Monohydrate von aminobenzensulfonsäurederivaten und verfahren zu ihrer herstellung |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US5990113A (de) |
| EP (1) | EP0779283B1 (de) |
| AT (1) | ATE190054T1 (de) |
| CA (1) | CA2192731C (de) |
| DE (1) | DE69606840T2 (de) |
| DK (1) | DK0779283T3 (de) |
| ES (1) | ES2143132T3 (de) |
| GR (1) | GR3033231T3 (de) |
| PT (1) | PT779283E (de) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2192731C (en) * | 1995-12-15 | 2005-09-27 | Chika Yamazaki | Monohydrates of aminobenzenesulfonic acid derivatives and method for preparing thereof |
| EP1062948B1 (de) * | 1998-02-12 | 2010-01-06 | Mitsubishi Chemical Corporation | Arzneimittel für nicht-cardiogene diastolische dysfunktion |
| US6586000B2 (en) * | 1999-12-16 | 2003-07-01 | Dermatrends, Inc. | Hydroxide-releasing agents as skin permeation enhancers |
| US6645520B2 (en) | 1999-12-16 | 2003-11-11 | Dermatrends, Inc. | Transdermal administration of nonsteroidal anti-inflammatory drugs using hydroxide-releasing agents as permeation enhancers |
| US20030104041A1 (en) * | 1999-12-16 | 2003-06-05 | Tsung-Min Hsu | Transdermal and topical administration of drugs using basic permeation enhancers |
| US6558695B2 (en) | 1999-12-16 | 2003-05-06 | Dermatrends, Inc. | Topical and transdermal administration of peptidyl drugs using hydroxide releasing agents as permeation enhancers |
| US6562370B2 (en) * | 1999-12-16 | 2003-05-13 | Dermatrends, Inc. | Transdermal administration of steroid drugs using hydroxide-releasing agents as permeation enhancers |
| US6565879B1 (en) | 1999-12-16 | 2003-05-20 | Dermatrends, Inc. | Topical and transdermal administration of peptidyl drugs with hydroxide-releasing agents as skin permeation enhancers |
| US6562368B2 (en) * | 1999-12-16 | 2003-05-13 | Dermatrends, Inc. | Transdermal administration of oxybutynin using hydroxide-releasing agents as permeation enhancers |
| US6673363B2 (en) * | 1999-12-16 | 2004-01-06 | Dermatrends, Inc. | Transdermal and topical administration of local anesthetic agents using basic enhancers |
| US6582724B2 (en) * | 1999-12-16 | 2003-06-24 | Dermatrends, Inc. | Dual enhancer composition for topical and transdermal drug delivery |
| US6562369B2 (en) * | 1999-12-16 | 2003-05-13 | Dermatrends, Inc. | Transdermal administration of androgenic drugs hydroxide-releasing agents as permeation enhancers |
| ES2233493T3 (es) * | 1999-12-21 | 2005-06-16 | Mitsubishi Pharma Corporation | Agentes terapeuticos y/o profilacticos para trastornos del sistema nervioso. |
| WO2002034735A1 (fr) * | 2000-10-23 | 2002-05-02 | Fujisawa Pharmaceutical Co., Ltd. | Procede de preparation d'un solvate et solvate |
| EP1374868A4 (de) * | 2001-03-13 | 2005-03-09 | Mitsubishi Pharma Corp | Mittel zur behandlung und/oder verhütung von diabetischen ischämischen herzerkrankungen |
| JP2004538292A (ja) * | 2001-07-25 | 2004-12-24 | 三菱ウェルファーマ株式会社 | ナトリウム・カルシウム交換系を阻害する医薬 |
| US20050004139A1 (en) * | 2001-07-30 | 2005-01-06 | Takeshi Inamori | Pharmaceutical preparations containing aminobenzene-sulfonic acid derivatives as the active ingredient |
| WO2004019946A1 (ja) * | 2002-08-30 | 2004-03-11 | Mitsubishi Pharma Corporation | 細胞内ナトリウムイオン過蓄積抑制薬 |
| JPWO2004022545A1 (ja) * | 2002-09-06 | 2005-12-22 | 三菱ウェルファーマ株式会社 | 移植臓器保護剤 |
| US7067867B2 (en) * | 2002-09-30 | 2006-06-27 | Nanosys, Inc. | Large-area nonenabled macroelectronic substrates and uses therefor |
| US7491725B2 (en) | 2004-02-06 | 2009-02-17 | Bristol-Myers Squibb Company | Process for preparing 2-aminothiazole-5-aromatic carboxamides as kinase inhibitors |
| KR20070026443A (ko) * | 2004-03-05 | 2007-03-08 | 미쯔비시 웰 파마 가부시키가이샤 | 허혈성 순환기 질환의 예방 및/또는 치료를 위한 약제 |
| US7115971B2 (en) * | 2004-03-23 | 2006-10-03 | Nanosys, Inc. | Nanowire varactor diode and methods of making same |
| AU2006252815A1 (en) * | 2005-06-02 | 2006-12-07 | Nanosys, Inc. | Light emitting nanowires for macroelectronics |
| WO2008010567A1 (fr) | 2006-07-21 | 2008-01-24 | Mitsubishi Tanabe Pharma Corporation | Sel ou solvate d'acide 5-méthyl-2-(pipérazin-1-yl)benzènesulfonique |
| US20090318461A1 (en) * | 2006-07-21 | 2009-12-24 | Chika Ohno | Crystalline polymorphism of 5-methyl-2-(piperazin-1-yl) benzenesulfonic acid |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE390654C (de) | 1922-03-19 | 1924-02-24 | Paul Lucas | Bunsenbrenner fuer fluessige Brennstoffe |
| GB1450746A (en) * | 1974-01-31 | 1976-09-29 | Ici Ltd | Tripendioxazine dyestuffs |
| US4411904A (en) * | 1981-05-29 | 1983-10-25 | Warner-Lambert Company | Diphenylpropanamines, compositions thereof and use thereof |
| GB2126598A (en) * | 1982-08-16 | 1984-03-28 | Ici Plc | Reactive dyestuffs |
| US5053409A (en) * | 1989-03-27 | 1991-10-01 | Mitsubishi Kasei Corporation | Aminobenzenesulfonic acid derivatives |
| JPH0686438B2 (ja) * | 1989-03-27 | 1994-11-02 | 三菱化成株式会社 | アミノベンゼンスルホン酸誘導体 |
| JP3083544B2 (ja) | 1990-09-27 | 2000-09-04 | 三菱化学株式会社 | 心疾患を予防または治療する薬剤 |
| JP2951476B2 (ja) | 1992-03-27 | 1999-09-20 | 古河電気工業株式会社 | 水底布設長尺体の水中引入方法 |
| US5486517A (en) * | 1994-05-10 | 1996-01-23 | Warner-Lambert Company | Benzimidazoles and imidazopyridines as central nervous system agents |
| US5457107A (en) * | 1994-09-16 | 1995-10-10 | Merck & Co., Inc. | Polymorphic form of a tachykinin receptor antagonist |
| CA2192731C (en) * | 1995-12-15 | 2005-09-27 | Chika Yamazaki | Monohydrates of aminobenzenesulfonic acid derivatives and method for preparing thereof |
-
1996
- 1996-12-12 CA CA002192731A patent/CA2192731C/en not_active Expired - Fee Related
- 1996-12-14 DK DK96120136T patent/DK0779283T3/da active
- 1996-12-14 EP EP96120136A patent/EP0779283B1/de not_active Expired - Lifetime
- 1996-12-14 AT AT96120136T patent/ATE190054T1/de active
- 1996-12-14 ES ES96120136T patent/ES2143132T3/es not_active Expired - Lifetime
- 1996-12-14 PT PT96120136T patent/PT779283E/pt unknown
- 1996-12-14 DE DE69606840T patent/DE69606840T2/de not_active Expired - Lifetime
- 1996-12-16 US US08/767,062 patent/US5990113A/en not_active Expired - Fee Related
-
1999
- 1999-09-24 US US09/404,817 patent/US6245767B1/en not_active Expired - Fee Related
-
2000
- 2000-03-30 GR GR20000400806T patent/GR3033231T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PT779283E (pt) | 2000-08-31 |
| CA2192731A1 (en) | 1997-06-16 |
| DE69606840D1 (de) | 2000-04-06 |
| EP0779283A1 (de) | 1997-06-18 |
| US6245767B1 (en) | 2001-06-12 |
| DE69606840T2 (de) | 2000-10-12 |
| DK0779283T3 (da) | 2000-06-26 |
| ES2143132T3 (es) | 2000-05-01 |
| US5990113A (en) | 1999-11-23 |
| CA2192731C (en) | 2005-09-27 |
| GR3033231T3 (en) | 2000-08-31 |
| EP0779283B1 (de) | 2000-03-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE190054T1 (de) | Monohydrate von aminobenzensulfonsäurederivaten und verfahren zu ihrer herstellung | |
| ATE131173T1 (de) | Fluorierte gallensäure-derivate, verfahren zu deren herstellung und pharmazeutische zusammensetzungen daraus. | |
| DE69027440D1 (de) | Bizyklische pyrimidinderivate, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzung | |
| EP0624594A3 (de) | Monomere Gallensäurederivate, Verfahren zu ihrer Herstellung und Verwendung dieser Verbindungen als Arzneimittel. | |
| ATE40368T1 (de) | Xanthin-derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen. | |
| NO177004C (no) | Analogifremgangsmåte for fremstilling av 7-substituerte derivater av 3,5-dihydroksyhept-6-ynsyre | |
| ATE302778T1 (de) | N-substituierte 4-aminopteridine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel | |
| ATE13056T1 (de) | Indanderivate, verfahren zu ihrer herstellung und sie enthaltende zusammensetzungen. | |
| ATE124953T1 (de) | Gallensäure-derivate, verfahren zu deren herstellung und pharmazeutische zusammensetzungen daraus. | |
| ATE201024T1 (de) | Carbamatderivate von 4-amino-3-isoxazolidinonen und 3-amino-1-hydroxypyrrolidinon-2-onen, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel | |
| DE3485419D1 (de) | Glyzerinderivate. | |
| ATE3429T1 (de) | Paromomycin-derivate, verfahren zu deren herstellung und sie enthaltende pharmazeutische zusammenzetzung. | |
| ATE214051T1 (de) | Substituierte tetrahydropyridinderivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel | |
| ATE165822T1 (de) | Chinolin-4-carbonylguanidin-derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen | |
| ATE140213T1 (de) | N-monosubstituierte cyclopentenylamine, ein verfahren zu ihrer herstellung, und ihre verwendung als medikament | |
| DE69130266D1 (de) | Optisch wirksame Alkylendioxybenzolderivate und ihre Verwendung als Arzneimittel | |
| DE69007422D1 (de) | 1-(4-Aminophenyl)-2-piperidinopropanon-Derivate, Verfahren zu deren Herstellung und therapeutische Verwendung. | |
| IT1237529B (it) | Composti spiro-indolino-ossazine con caratteristiche fotocromatiche e fotosensibilizzatrici e procedimento per la loro preparazione | |
| FR2703048B1 (fr) | Nouveaux composes n-benzylpiperazine, leur procede de preparation et les compositions pharmaceutiques les renfermant. | |
| ATE112276T1 (de) | Aryl-chinolyl-substituierte 1,4-dihydropyridin- dicarbonsäurederivate, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln. | |
| FI905930A7 (fi) | Menetelmä uusien, farmakologisesti käyttökelpoisten bispilokarpiinihapon esterijohdannaisten valmistamiseksi | |
| EP0802179A4 (de) | Derivate substituierter amidinonaphthylester | |
| FI903531A0 (fi) | Menetelmä lääkeaineina käyttökelpoisten 2-imino-3-heterosyklyylialkyylibentsotiatsoliinijohdannaisten valmistamiseksi | |
| ATE12390T1 (de) | Basisch substituierte anthranilsaeuren, verfahren zu ihrer herstellung und ihre verwendung. | |
| DE69401163D1 (de) | Umwandlungsverfahren von Lorabef Dihydrate in Loracarbef Monohydrate |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |