DK0779283T3 - Monohydrater af aminobenzensulfonsyrederivater og fremgangsmåde til fremstilling heraf - Google Patents
Monohydrater af aminobenzensulfonsyrederivater og fremgangsmåde til fremstilling herafInfo
- Publication number
- DK0779283T3 DK0779283T3 DK96120136T DK96120136T DK0779283T3 DK 0779283 T3 DK0779283 T3 DK 0779283T3 DK 96120136 T DK96120136 T DK 96120136T DK 96120136 T DK96120136 T DK 96120136T DK 0779283 T3 DK0779283 T3 DK 0779283T3
- Authority
- DK
- Denmark
- Prior art keywords
- monohydrates
- preparation
- aminobenzenesulfonic acid
- acid derivatives
- monohydrate
- Prior art date
Links
- 150000004682 monohydrates Chemical class 0.000 title abstract 3
- ZMCHBSMFKQYNKA-UHFFFAOYSA-N 2-aminobenzenesulfonic acid Chemical class NC1=CC=CC=C1S(O)(=O)=O ZMCHBSMFKQYNKA-UHFFFAOYSA-N 0.000 title abstract 2
- DCDFLGVJWQIRGH-UHFFFAOYSA-N 5-methyl-2-piperazin-4-ium-1-ylbenzenesulfonate Chemical compound OS(=O)(=O)C1=CC(C)=CC=C1N1CCNCC1 DCDFLGVJWQIRGH-UHFFFAOYSA-N 0.000 abstract 1
- 238000010521 absorption reaction Methods 0.000 abstract 1
- 208000019622 heart disease Diseases 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/08—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 not condensed with other rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP32664895 | 1995-12-15 | ||
| JP32706895 | 1995-12-15 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0779283T3 true DK0779283T3 (da) | 2000-06-26 |
Family
ID=26572248
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK96120136T DK0779283T3 (da) | 1995-12-15 | 1996-12-14 | Monohydrater af aminobenzensulfonsyrederivater og fremgangsmåde til fremstilling heraf |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US5990113A (de) |
| EP (1) | EP0779283B1 (de) |
| AT (1) | ATE190054T1 (de) |
| CA (1) | CA2192731C (de) |
| DE (1) | DE69606840T2 (de) |
| DK (1) | DK0779283T3 (de) |
| ES (1) | ES2143132T3 (de) |
| GR (1) | GR3033231T3 (de) |
| PT (1) | PT779283E (de) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2192731C (en) * | 1995-12-15 | 2005-09-27 | Chika Yamazaki | Monohydrates of aminobenzenesulfonic acid derivatives and method for preparing thereof |
| CN1198617C (zh) * | 1998-02-12 | 2005-04-27 | 三菱化学株式会社 | 治疗心脏舒张功能障碍的药物 |
| US6586000B2 (en) * | 1999-12-16 | 2003-07-01 | Dermatrends, Inc. | Hydroxide-releasing agents as skin permeation enhancers |
| US6673363B2 (en) * | 1999-12-16 | 2004-01-06 | Dermatrends, Inc. | Transdermal and topical administration of local anesthetic agents using basic enhancers |
| US6565879B1 (en) | 1999-12-16 | 2003-05-20 | Dermatrends, Inc. | Topical and transdermal administration of peptidyl drugs with hydroxide-releasing agents as skin permeation enhancers |
| US6582724B2 (en) * | 1999-12-16 | 2003-06-24 | Dermatrends, Inc. | Dual enhancer composition for topical and transdermal drug delivery |
| US6562368B2 (en) * | 1999-12-16 | 2003-05-13 | Dermatrends, Inc. | Transdermal administration of oxybutynin using hydroxide-releasing agents as permeation enhancers |
| US6558695B2 (en) | 1999-12-16 | 2003-05-06 | Dermatrends, Inc. | Topical and transdermal administration of peptidyl drugs using hydroxide releasing agents as permeation enhancers |
| US6562370B2 (en) * | 1999-12-16 | 2003-05-13 | Dermatrends, Inc. | Transdermal administration of steroid drugs using hydroxide-releasing agents as permeation enhancers |
| US6645520B2 (en) * | 1999-12-16 | 2003-11-11 | Dermatrends, Inc. | Transdermal administration of nonsteroidal anti-inflammatory drugs using hydroxide-releasing agents as permeation enhancers |
| US6562369B2 (en) * | 1999-12-16 | 2003-05-13 | Dermatrends, Inc. | Transdermal administration of androgenic drugs hydroxide-releasing agents as permeation enhancers |
| US20030104041A1 (en) * | 1999-12-16 | 2003-06-05 | Tsung-Min Hsu | Transdermal and topical administration of drugs using basic permeation enhancers |
| US7652017B2 (en) * | 1999-12-21 | 2010-01-26 | Mitsubishi Tanabe Pharma Corporation | Remedies and/or preventives for nervous system disorders |
| JPWO2002034735A1 (ja) * | 2000-10-23 | 2004-03-04 | 藤沢薬品工業株式会社 | 溶媒和物の取得方法及び溶媒和物 |
| JP4246997B2 (ja) * | 2001-03-13 | 2009-04-02 | 田辺三菱製薬株式会社 | 糖尿病由来虚血性心疾患の治療及び／または予防剤 |
| CN100502861C (zh) * | 2001-07-25 | 2009-06-24 | 田边三菱制药株式会社 | 抑制钠/钙交换系统的药剂 |
| JPWO2003011296A1 (ja) * | 2001-07-30 | 2004-11-18 | 三菱ウェルファーマ株式会社 | アミノベンゼンスルホン酸誘導体を活性成分とする医薬品製剤 |
| WO2004019946A1 (ja) * | 2002-08-30 | 2004-03-11 | Mitsubishi Pharma Corporation | 細胞内ナトリウムイオン過蓄積抑制薬 |
| AU2003261968A1 (en) * | 2002-09-06 | 2004-03-29 | Mitsubishi Pharma Corporation | Protective agents for transplanted organ |
| US7067867B2 (en) * | 2002-09-30 | 2006-06-27 | Nanosys, Inc. | Large-area nonenabled macroelectronic substrates and uses therefor |
| US7491725B2 (en) | 2004-02-06 | 2009-02-17 | Bristol-Myers Squibb Company | Process for preparing 2-aminothiazole-5-aromatic carboxamides as kinase inhibitors |
| CN1946396A (zh) * | 2004-03-05 | 2007-04-11 | 三菱制药株式会社 | 用于预防和/或治疗缺血性循环器官疾病的药剂 |
| US7115971B2 (en) * | 2004-03-23 | 2006-10-03 | Nanosys, Inc. | Nanowire varactor diode and methods of making same |
| WO2006130359A2 (en) * | 2005-06-02 | 2006-12-07 | Nanosys, Inc. | Light emitting nanowires for macroelectronics |
| JPWO2008010567A1 (ja) | 2006-07-21 | 2009-12-17 | 田辺三菱製薬株式会社 | ５−メチル‐２‐（ピペラジン−１−イル）ベンゼンスルホン酸の塩形態又は溶媒和物 |
| WO2008010566A1 (fr) | 2006-07-21 | 2008-01-24 | Mitsubishi Tanabe Pharma Corporation | Polymorphisme cristallin de l'acide 5-méthyl-2-(pipérazin-1-yl)-benzènesulfonique |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE390654C (de) | 1922-03-19 | 1924-02-24 | Paul Lucas | Bunsenbrenner fuer fluessige Brennstoffe |
| GB1450746A (en) * | 1974-01-31 | 1976-09-29 | Ici Ltd | Tripendioxazine dyestuffs |
| US4411904A (en) * | 1981-05-29 | 1983-10-25 | Warner-Lambert Company | Diphenylpropanamines, compositions thereof and use thereof |
| GB2126598A (en) * | 1982-08-16 | 1984-03-28 | Ici Plc | Reactive dyestuffs |
| US5053409A (en) * | 1989-03-27 | 1991-10-01 | Mitsubishi Kasei Corporation | Aminobenzenesulfonic acid derivatives |
| JPH0686438B2 (ja) | 1989-03-27 | 1994-11-02 | 三菱化成株式会社 | アミノベンゼンスルホン酸誘導体 |
| JP3083544B2 (ja) | 1990-09-27 | 2000-09-04 | 三菱化学株式会社 | 心疾患を予防または治療する薬剤 |
| JP2951476B2 (ja) | 1992-03-27 | 1999-09-20 | 古河電気工業株式会社 | 水底布設長尺体の水中引入方法 |
| US5486517A (en) * | 1994-05-10 | 1996-01-23 | Warner-Lambert Company | Benzimidazoles and imidazopyridines as central nervous system agents |
| US5457107A (en) * | 1994-09-16 | 1995-10-10 | Merck & Co., Inc. | Polymorphic form of a tachykinin receptor antagonist |
| CA2192731C (en) * | 1995-12-15 | 2005-09-27 | Chika Yamazaki | Monohydrates of aminobenzenesulfonic acid derivatives and method for preparing thereof |
-
1996
- 1996-12-12 CA CA002192731A patent/CA2192731C/en not_active Expired - Fee Related
- 1996-12-14 PT PT96120136T patent/PT779283E/pt unknown
- 1996-12-14 DK DK96120136T patent/DK0779283T3/da active
- 1996-12-14 EP EP96120136A patent/EP0779283B1/de not_active Expired - Lifetime
- 1996-12-14 DE DE69606840T patent/DE69606840T2/de not_active Expired - Lifetime
- 1996-12-14 AT AT96120136T patent/ATE190054T1/de active
- 1996-12-14 ES ES96120136T patent/ES2143132T3/es not_active Expired - Lifetime
- 1996-12-16 US US08/767,062 patent/US5990113A/en not_active Expired - Fee Related
-
1999
- 1999-09-24 US US09/404,817 patent/US6245767B1/en not_active Expired - Fee Related
-
2000
- 2000-03-30 GR GR20000400806T patent/GR3033231T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0779283B1 (de) | 2000-03-01 |
| EP0779283A1 (de) | 1997-06-18 |
| DE69606840T2 (de) | 2000-10-12 |
| ES2143132T3 (es) | 2000-05-01 |
| US6245767B1 (en) | 2001-06-12 |
| ATE190054T1 (de) | 2000-03-15 |
| GR3033231T3 (en) | 2000-08-31 |
| DE69606840D1 (de) | 2000-04-06 |
| CA2192731A1 (en) | 1997-06-16 |
| CA2192731C (en) | 2005-09-27 |
| US5990113A (en) | 1999-11-23 |
| PT779283E (pt) | 2000-08-31 |
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