ATE192331T1 - Abgabesystem für impfstoffe und lagerstabile vorstufenlösung zur nachträglichen verkapselung von aktivstoffen - Google Patents

Abgabesystem für impfstoffe und lagerstabile vorstufenlösung zur nachträglichen verkapselung von aktivstoffen

Info

Publication number
ATE192331T1
ATE192331T1 AT94909807T AT94909807T ATE192331T1 AT E192331 T1 ATE192331 T1 AT E192331T1 AT 94909807 T AT94909807 T AT 94909807T AT 94909807 T AT94909807 T AT 94909807T AT E192331 T1 ATE192331 T1 AT E192331T1
Authority
AT
Austria
Prior art keywords
storage
delivery system
pct
active ingredients
encapsulation
Prior art date
Application number
AT94909807T
Other languages
English (en)
Inventor
Michael W Fountain
Original Assignee
Fountain Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fountain Pharm Inc filed Critical Fountain Pharm Inc
Application granted granted Critical
Publication of ATE192331T1 publication Critical patent/ATE192331T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1277—Preparation processes; Proliposomes
    • A61K9/1278—Post-loading, e.g. by ion or pH gradient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541—Mucosal route
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
AT94909807T 1993-02-26 1994-02-25 Abgabesystem für impfstoffe und lagerstabile vorstufenlösung zur nachträglichen verkapselung von aktivstoffen ATE192331T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2397193A 1993-02-26 1993-02-26
PCT/US1994/002053 WO1994018950A1 (en) 1993-02-26 1994-02-25 Vaccine delivery system and shelf-stable precursor solution for remote encapsulation of active ingredients

Publications (1)

Publication Number Publication Date
ATE192331T1 true ATE192331T1 (de) 2000-05-15

Family

ID=21818176

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94909807T ATE192331T1 (de) 1993-02-26 1994-02-25 Abgabesystem für impfstoffe und lagerstabile vorstufenlösung zur nachträglichen verkapselung von aktivstoffen

Country Status (12)

Country Link
US (1) US5879703A (de)
EP (1) EP0688206B1 (de)
JP (1) JPH08507077A (de)
AT (1) ATE192331T1 (de)
AU (1) AU677826B2 (de)
CA (1) CA2157125A1 (de)
DE (1) DE69424279T2 (de)
DK (1) DK0688206T3 (de)
ES (1) ES2145132T3 (de)
PT (1) PT688206E (de)
SG (1) SG44911A1 (de)
WO (1) WO1994018950A1 (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5629020A (en) * 1994-04-22 1997-05-13 Emisphere Technologies, Inc. Modified amino acids for drug delivery
IL126318A (en) 1996-03-29 2004-09-27 Emisphere Tech Inc Compounds and compositions for delivering active agents and some novel carrier compounds
US6358504B1 (en) 1997-02-07 2002-03-19 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
EP1754488A1 (de) 1999-05-24 2007-02-21 Introgen Therapeutics, Inc. Verfahren und Zusammensetzungen für nichtvirale Gentherapie zur Behandlung von hyperproliferativen Krankheiten
US10293056B1 (en) 2000-05-24 2019-05-21 Board Of Regents, The University Of Texas System Methods and compositions for non-viral gene therapy for treatment of hyperproliferative diseases
US6984395B2 (en) * 2001-04-11 2006-01-10 Qlt, Inc. Drug delivery system for hydrophobic drugs
US20060073530A1 (en) * 2001-08-15 2006-04-06 Olaf Schneewind Methods and compositions involving sortase B
US20140271782A1 (en) 2013-03-15 2014-09-18 Dermazone Solutions, Inc. Method for preparing nanolipids with encapsulated alcohol
ES2625111T3 (es) * 2005-12-30 2017-07-18 Nuvessl Inc. Partículas nanolipídicas
WO2007092944A2 (en) * 2006-02-08 2007-08-16 Introgen Therapeutics, Inc. Compositions and methods involving gene therapy and proteasome modulation
US20140335166A1 (en) * 2013-05-08 2014-11-13 Michael W. Fountain Methods of Making and Using Nano Scale Particles
US9746471B2 (en) 2008-01-25 2017-08-29 Multivir Inc. P53 biomarkers
US9445975B2 (en) * 2008-10-03 2016-09-20 Access Business Group International, Llc Composition and method for preparing stable unilamellar liposomal suspension
EP2451950B9 (de) 2009-07-06 2016-11-23 Variation Biotechnologies Inc. Verfahren zur vesikelherstellung und darin hergestellte formulierungen
WO2011005772A1 (en) 2009-07-06 2011-01-13 Variation Biotechnologies, Inc. Methods for preparing vesicles and formulations produced therefrom
BR112013000394B8 (pt) 2010-07-06 2022-01-18 Variation Biotechnologies Inc Composição imunogênica, uso da mesma e método para preparar a referida composição
CN107296792B (zh) * 2011-01-13 2021-07-27 变异生物技术公司 囊泡及由其产生之制剂的制备方法
EP2663327A4 (de) 2011-01-13 2015-12-02 Variation Biotechnologies Inc Zusammensetzungen und verfahren zur behandlung von virusinfektionen
US9333675B2 (en) * 2012-01-10 2016-05-10 Hzo, Inc. Profiles for precursors to polymeric materials
US20140356399A1 (en) 2012-01-12 2014-12-04 Variation Biotechnologies, Inc. Compositions and methods for treating viral infections
EP4008354A1 (de) 2012-01-27 2022-06-08 Variation Biotechnologies Inc. Verfahren und zusammensetzungen für therapeutika
KR20180016347A (ko) * 2015-04-13 2018-02-14 파운테인 테크놀로지스 인터내셔널, 엘엘씨 초-소형 지질 구조체의 생산을 위한 단일-단계 방법
US20200078427A1 (en) 2018-09-06 2020-03-12 NuVessl, Inc. Cannabis Sativa Derived Formulation for Transmucosal and Transdermal Delivery
US11458092B2 (en) 2018-12-14 2022-10-04 NuVessl, Inc. Composition with enhanced passenger molecule loading

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1695599A (en) * 1927-05-24 1928-12-18 Edward L Merzoian Dispenser
US2261877A (en) * 1940-05-15 1941-11-04 John G Erickson Dispensing device
US2712400A (en) * 1952-04-28 1955-07-05 Wayne C Stauffer Dispensing means for paste tubes
US3780911A (en) * 1972-01-03 1973-12-25 D Paige Dispensing apparatus for collapsible tube container
AU549154B2 (en) * 1982-12-07 1986-01-16 Motion, J.A.C. Collapsible tube expressor
US4588578A (en) * 1983-08-08 1986-05-13 The Liposome Company, Inc. Lipid vesicles prepared in a monophase
US4755375A (en) * 1984-01-27 1988-07-05 Associated Universities, Inc. Method and kit for the selective labeling of red blood cells in whole blood with TC-99M
US4610868A (en) * 1984-03-20 1986-09-09 The Liposome Company, Inc. Lipid matrix carriers for use in drug delivery systems
DE3775783D1 (de) * 1986-01-14 1992-02-20 Nederlanden Staat Verfahren zur herstellung immunologischer komplexe und diese enthaltende pharmazeutische zusammensetzung.
US5049388A (en) * 1986-11-06 1991-09-17 Research Development Foundation Small particle aerosol liposome and liposome-drug combinations for medical use
US5269979A (en) * 1988-06-08 1993-12-14 Fountain Pharmaceuticals, Inc. Method for making solvent dilution microcarriers
IL90561A (en) * 1988-06-08 1993-08-18 Fountain Pharm Inc Method for making solvent dilution microcarriers
US5133965A (en) * 1988-06-08 1992-07-28 Fountain Pharmaceuticals, Inc. Dressing material having adsorbed thereon a solvent dilution microcarrier precursor solution
NZ230424A (en) * 1988-08-25 1992-05-26 Liposome Co Inc Liposomal composition comprising an externally disposed antigen
US5100662A (en) * 1989-08-23 1992-03-31 The Liposome Company, Inc. Steroidal liposomes exhibiting enhanced stability
DE4136553A1 (de) * 1991-11-06 1993-05-13 Biotechnolog Forschung Gmbh Impfstoff gegen schleimhauterreger und herstellungsverfahren

Also Published As

Publication number Publication date
WO1994018950A1 (en) 1994-09-01
DK0688206T3 (da) 2000-09-25
EP0688206A1 (de) 1995-12-27
CA2157125A1 (en) 1994-09-01
JPH08507077A (ja) 1996-07-30
US5879703A (en) 1999-03-09
AU6250694A (en) 1994-09-14
DE69424279T2 (de) 2000-12-21
HK1012991A1 (en) 1999-08-13
SG44911A1 (en) 1997-12-19
AU677826B2 (en) 1997-05-08
PT688206E (pt) 2000-08-31
EP0688206B1 (de) 2000-05-03
ES2145132T3 (es) 2000-07-01
DE69424279D1 (de) 2000-06-08

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee