ATE192489T1 - Tumorsuppressor-gen merlin und dessen verwendungen - Google Patents
Tumorsuppressor-gen merlin und dessen verwendungenInfo
- Publication number
- ATE192489T1 ATE192489T1 AT94301367T AT94301367T ATE192489T1 AT E192489 T1 ATE192489 T1 AT E192489T1 AT 94301367 T AT94301367 T AT 94301367T AT 94301367 T AT94301367 T AT 94301367T AT E192489 T1 ATE192489 T1 AT E192489T1
- Authority
- AT
- Austria
- Prior art keywords
- merlin
- tumor suppressor
- suppressor gene
- diagnosis
- treatment
- Prior art date
Links
- 108700025716 Tumor Suppressor Genes Proteins 0.000 title 1
- 102000044209 Tumor Suppressor Genes Human genes 0.000 title 1
- 241000272186 Falco columbarius Species 0.000 abstract 4
- 206010028980 Neoplasm Diseases 0.000 abstract 2
- 238000003745 diagnosis Methods 0.000 abstract 2
- 208000002761 neurofibromatosis 2 Diseases 0.000 abstract 2
- 208000022032 neurofibromatosis type 2 Diseases 0.000 abstract 2
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 239000013598 vector Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/82—Translation products from oncogenes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oncology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2203493A | 1993-02-25 | 1993-02-25 | |
| US2606393A | 1993-03-04 | 1993-03-04 | |
| US10880893A | 1993-08-19 | 1993-08-19 | |
| US08/171,718 US5707863A (en) | 1993-02-25 | 1993-12-22 | Tumor suppressor gene merlin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE192489T1 true ATE192489T1 (de) | 2000-05-15 |
Family
ID=27487063
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT94301367T ATE192489T1 (de) | 1993-02-25 | 1994-02-25 | Tumorsuppressor-gen merlin und dessen verwendungen |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US5707863A (de) |
| EP (1) | EP0613945B1 (de) |
| JP (1) | JPH07143884A (de) |
| AT (1) | ATE192489T1 (de) |
| CA (1) | CA2115404A1 (de) |
| DE (1) | DE69424209T2 (de) |
| DK (1) | DK0613945T3 (de) |
| ES (1) | ES2148283T3 (de) |
| GR (1) | GR3034057T3 (de) |
| PT (1) | PT613945E (de) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5578462A (en) * | 1994-01-10 | 1996-11-26 | Bristol-Myers Squibb Company | NF2 isoforms |
| AU2456397A (en) * | 1996-04-12 | 1997-11-07 | Muro Pharmaceutical, Inc. | Isolated and cloned mast cell 78 kda phosphoprotein (mast cell degranulation inhibitory agent) and use thereof |
| GB9812674D0 (en) * | 1998-06-12 | 1998-08-12 | Central Manchester Healthcare | Nucleic acids |
| US7053200B1 (en) | 1999-06-01 | 2006-05-30 | Baylor College Of Medicine | Compositions and methods for the therapeutic use of an atonal-associated sequence for deafness, osteoarthritis, and abnormal cell proliferation |
| DK1471926T3 (da) | 1999-06-01 | 2011-02-28 | Baylor College Medicine | Sammensætninger og fremgangsmåder til terapeutisk anvendelse af en atonal-associeret sekvens |
| AU6181300A (en) * | 1999-07-29 | 2001-02-19 | Helix Research Institute | Liver cancer-associated genes |
| AU2953201A (en) * | 2000-01-20 | 2001-07-31 | Genome Therapeutics Corporation | Rapid determination of gene structure using cdna sequence |
| ES2291246T3 (es) * | 2000-06-27 | 2008-03-01 | Von Recklinghausen Gesellschaft E.V. | Procedimiento para adquirir datos para el diagnostico presintomatico o prenatal de neurofribromatosis del tipo 1. |
| US20040014699A1 (en) * | 2002-07-18 | 2004-01-22 | Isis Pharmaceuticals, Inc. | Antisense modulation of PTPRM expression |
| US20040249023A1 (en) * | 2003-01-17 | 2004-12-09 | Stoffer James O. | Compounds for corrosion resistant primer coatings and protection of metal substrates |
| CA2862580A1 (en) * | 2011-10-28 | 2013-05-02 | Millennium Pharmaceuticals, Inc. | Biomarkers of response to nae inhibitors |
| TWI710635B (zh) | 2014-10-09 | 2020-11-21 | 美商珍維克公司 | 編碼人類無調同源物-1(hath1)之腺病毒載體 |
| CN110846309B (zh) * | 2018-08-20 | 2023-03-24 | 中国农业科学院兰州兽医研究所 | 用于鉴定多房棘球绦虫引物对、引物探针组以及他们的应用 |
| AU2022257000A1 (en) * | 2021-04-14 | 2023-11-30 | Nicole Christine HENWOOD | Materials and methods for neurofibromin 2/merlin (nf2) gene therapy |
| WO2022261209A1 (en) * | 2021-06-08 | 2022-12-15 | Nf2 Therapeutics, Inc. | Compositions and methods for treating neurofibromatic disorders |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0448650A4 (en) * | 1989-02-01 | 1992-05-13 | The General Hospital Corporation | Herpes simplex virus type i expression vector |
| WO1993003743A1 (en) * | 1991-08-16 | 1993-03-04 | The General Hospital Corporation | Method of gene delivery to post-mitotic cells |
| US5578462A (en) * | 1994-01-10 | 1996-11-26 | Bristol-Myers Squibb Company | NF2 isoforms |
-
1993
- 1993-12-22 US US08/171,718 patent/US5707863A/en not_active Expired - Lifetime
-
1994
- 1994-02-10 CA CA002115404A patent/CA2115404A1/en not_active Abandoned
- 1994-02-24 JP JP6026416A patent/JPH07143884A/ja active Pending
- 1994-02-25 EP EP94301367A patent/EP0613945B1/de not_active Expired - Lifetime
- 1994-02-25 PT PT94301367T patent/PT613945E/pt unknown
- 1994-02-25 DE DE69424209T patent/DE69424209T2/de not_active Expired - Fee Related
- 1994-02-25 AT AT94301367T patent/ATE192489T1/de not_active IP Right Cessation
- 1994-02-25 DK DK94301367T patent/DK0613945T3/da active
- 1994-02-25 ES ES94301367T patent/ES2148283T3/es not_active Expired - Lifetime
-
1995
- 1995-06-07 US US08/478,087 patent/US6077685A/en not_active Expired - Lifetime
-
2000
- 2000-07-28 GR GR20000401749T patent/GR3034057T3/el not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DE69424209D1 (de) | 2000-06-08 |
| EP0613945A3 (de) | 1996-01-17 |
| GR3034057T3 (en) | 2000-11-30 |
| EP0613945A2 (de) | 1994-09-07 |
| DK0613945T3 (da) | 2000-09-25 |
| JPH07143884A (ja) | 1995-06-06 |
| DE69424209T2 (de) | 2001-01-25 |
| CA2115404A1 (en) | 1994-08-26 |
| EP0613945B1 (de) | 2000-05-03 |
| US5707863A (en) | 1998-01-13 |
| ES2148283T3 (es) | 2000-10-16 |
| PT613945E (pt) | 2000-10-31 |
| US6077685A (en) | 2000-06-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |