ATE193443T1 - Verwendung eines imidazols zur herstellung eines medikamentes zur behandlung der arteriosklerose - Google Patents

Verwendung eines imidazols zur herstellung eines medikamentes zur behandlung der arteriosklerose

Info

Publication number
ATE193443T1
ATE193443T1 AT94909690T AT94909690T ATE193443T1 AT E193443 T1 ATE193443 T1 AT E193443T1 AT 94909690 T AT94909690 T AT 94909690T AT 94909690 T AT94909690 T AT 94909690T AT E193443 T1 ATE193443 T1 AT E193443T1
Authority
AT
Austria
Prior art keywords
arteriosclerosis
medication
imidazole
treatment
production
Prior art date
Application number
AT94909690T
Other languages
English (en)
Inventor
Jose Halperin
Carlo Brugnara
Original Assignee
Harvard College
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Harvard College filed Critical Harvard College
Application granted granted Critical
Publication of ATE193443T1 publication Critical patent/ATE193443T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Saccharide Compounds (AREA)
AT94909690T 1993-02-18 1994-02-18 Verwendung eines imidazols zur herstellung eines medikamentes zur behandlung der arteriosklerose ATE193443T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/018,835 US5358959A (en) 1993-02-18 1993-02-18 Methods for treating arteriosclerosis
PCT/US1994/001749 WO1994018968A1 (en) 1993-02-18 1994-02-18 Methods for treating arteriosclerosis

Publications (1)

Publication Number Publication Date
ATE193443T1 true ATE193443T1 (de) 2000-06-15

Family

ID=21790012

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94909690T ATE193443T1 (de) 1993-02-18 1994-02-18 Verwendung eines imidazols zur herstellung eines medikamentes zur behandlung der arteriosklerose

Country Status (8)

Country Link
US (1) US5358959A (de)
EP (1) EP0646005B1 (de)
JP (1) JPH08503958A (de)
AT (1) ATE193443T1 (de)
AU (1) AU6243894A (de)
CA (1) CA2118314A1 (de)
DE (1) DE69424732D1 (de)
WO (1) WO1994018968A1 (de)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6515009B1 (en) 1991-09-27 2003-02-04 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US6395494B1 (en) 1993-05-13 2002-05-28 Neorx Corporation Method to determine TGF-β
US5633274A (en) * 1993-02-18 1997-05-27 President And Fellows Of Harvard College Cancer treatments
US5512591A (en) * 1993-02-18 1996-04-30 President And Fellows Of Harvard College Treatments for diseases characterized by neovascularization
GB2293323A (en) * 1994-09-12 1996-03-27 Orion Yhtymae Oy Antibiotics and bismuth salts for treating bacterial infections
EP0783303B1 (de) * 1994-09-16 2002-11-27 President And Fellows Of Harvard College Verwendung von aromatischen halogenverbindungen zur behandlung der zellproliferation in säugetieren
US6028103A (en) * 1994-09-16 2000-02-22 Children's Medical Center Corporation Triaryl methane compounds and analogues thereof useful for the treatment or prevention of sickle cell disease or diseases characterized by abnormal cell proliferation
DE19503160A1 (de) * 1995-02-01 1996-08-08 Bayer Ag Verwendung von Phenylcyclohexylcarbonsäureamiden
HRP960015B1 (en) * 1995-02-01 2000-12-31 Bayer Ag Substituted indole derivatives
US5556871A (en) * 1995-04-24 1996-09-17 President & Fellows Of Harvard College Method for treating epithelial precancerous lesions with topical inidazoles
US7611533B2 (en) 1995-06-07 2009-11-03 Cook Incorporated Coated implantable medical device
US5645839A (en) * 1995-06-07 1997-07-08 Trustees Of Boston University Combined use of angiotensin inhibitors and nitric oxide stimulators to treat fibrosis
US6346510B1 (en) 1995-10-23 2002-02-12 The Children's Medical Center Corporation Therapeutic antiangiogenic endostatin compositions
US5993787A (en) * 1996-09-13 1999-11-30 Johnson & Johnson Consumer Products, Inc. Composition base for topical therapeutic and cosmetic preparations
US6946439B2 (en) 1997-02-06 2005-09-20 Entre Med, Inc. Compositions and methods for inhibiting cellular proliferation comprising TFPI fragments
US5981471A (en) * 1997-02-06 1999-11-09 Entremed, Inc. Compositions and methods for inhibiting cellular proliferation
US20060025329A1 (en) * 1997-02-06 2006-02-02 Todd Hembrough Compositions and methods for inhibiting cellular proliferation comprising TFPI fragments
US6033357A (en) * 1997-03-28 2000-03-07 Navius Corporation Intravascular radiation delivery device
US6309339B1 (en) 1997-03-28 2001-10-30 Endosonics Corporation Intravascular radiation delivery device
BR9815617A (pt) 1997-11-20 2001-10-16 Harvard College Compostos substituìdos de 11-fenil-dibenzazepina, composição farmacêutica baseada nos referidos compostos, e métodos para inibir a proliferação de células de mamìferos e para tratamento ou prevenção de desordem causada por proliferação anormal de células
US6800658B2 (en) 1997-11-20 2004-10-05 Children's Medical Center Corporation Substituted diphenyl indanone, indane and indole compounds and analogues thereof useful for the treatment of prevention of diseases characterized by abnormal cell proliferation
US6992079B2 (en) * 1997-11-20 2006-01-31 President Fellows of Harvard College Substituted 11-phenyl-dibenzazepine compounds useful for the treatment or prevention of diseases characterized by abnormal cell proliferation
WO2000024402A1 (fr) * 1998-10-27 2000-05-04 Roumen Antonov Utilisation d'antifongiques dans le traitement des scleroses
US8026263B2 (en) * 2000-01-06 2011-09-27 The Regents Of The University Of California Methods for inhibiting neoproliferative changes in blood vessel walls
US6613083B2 (en) 2001-05-02 2003-09-02 Eckhard Alt Stent device and method
CA2448045A1 (fr) * 2001-05-23 2002-11-28 Roumen Antonov Identification de champignons parasites de l'organisme, et leur traitement
FR2825024B1 (fr) * 2001-05-23 2005-06-24 Roumen Antonov Identification de champignons parasites de l'organisme, et leur traitement
WO2003103580A2 (en) * 2002-06-10 2003-12-18 Combinatorx, Incorporated Combinations for the treatment of rheumatoid arthritis
KR100478671B1 (ko) * 2002-07-15 2005-03-22 사회복지법인 삼성생명공익재단 클로트리마졸을 포함하는 혈관 재협착 예방 및 치료용약학 조성물, 및 스텐트
CA2538991A1 (en) * 2003-09-18 2005-03-31 Children's Medical Center Corporation Treatment of severe distal colitis
WO2006084031A1 (en) * 2005-02-01 2006-08-10 Icagen, Inc. Imines as ion channel modulators
EP1924259A4 (de) * 2005-09-13 2009-04-01 Univ California Hemmung von calcium-aktivierten kaliumkanälen mittlerer konduktanz bei der behandlung und/oder prävention von atherosklerose
US20080090760A2 (en) * 2005-12-09 2008-04-17 Todd Hembrough Compositions and Methods for Inhibiting Cellular Proliferation
FR3070857B1 (fr) * 2017-09-11 2019-09-06 Centre Scientifique De Monaco Utilisation de la scleritine en tant qu'agent protecteur de cellules contre des agents toxiques

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4916118A (en) * 1986-08-18 1990-04-10 Board Of Regents, The University Of Texas System Pharmaceutical administration systems containing chemotactic peptides
US5132315A (en) * 1989-05-19 1992-07-21 The United States Of America As Represented By The Department Of Health And Human Services Therapeutic application of an anti-invasive compound
EP0525123B1 (de) * 1990-06-20 1997-09-17 PHARMACIA & UPJOHN COMPANY Antiatherosklerotische und antithrombotische 1-benzopyran-4-on- und 2-amino-1,3-benzoxazin-4-on-derivate

Also Published As

Publication number Publication date
DE69424732D1 (de) 2000-07-06
EP0646005B1 (de) 2000-05-31
US5358959A (en) 1994-10-25
CA2118314A1 (en) 1994-09-01
EP0646005A4 (de) 1996-03-27
EP0646005A1 (de) 1995-04-05
JPH08503958A (ja) 1996-04-30
AU6243894A (en) 1994-09-14
WO1994018968A1 (en) 1994-09-01

Similar Documents

Publication Publication Date Title
ATE193443T1 (de) Verwendung eines imidazols zur herstellung eines medikamentes zur behandlung der arteriosklerose
DE69435137D1 (de) Prävention und behandlung von pathologien, die mit einer abnormalen proliferationglatter muskelzellen verbunden sind
ATE407573T1 (de) Verwendung von lokal verabreichten lysine zur verbesserung der vaskularen funktion
DK0786991T3 (da) Polyaminforbindelsre til behandling af proliferative karsygdomme
ATE218164T1 (de) Hemmung der fortpflanzung von arterienglattmuskelzellen
YU45843B (sh) Postupak za dobijanje nosećeg katalizatora za polimerizaciju etilena
ATE225176T1 (de) Verwendung von serotonin-antagonisten (5ht3) zur behandlung von fibromyalgie
ATE191143T1 (de) Verwendung von nichtsteroidalen cyclooxygenasehemmern zur herstellung eines medikaments zur behandlung vom erhoehten augeninnendruck
JPS53108088A (en) Production of titanium catalyst component
ATE196083T1 (de) Verwendung von ferrioxamin-b zur behandlung septischen schocks
ATE272404T1 (de) Verwendung von taurolidine zur herstellung eines arzneimittels zur behandlung von leukämien
DK1479394T3 (da) Anvendelse af epidermal vækstfaktor (EGF) til ögning af vækstforögelse hos et dyr
DE69506686D1 (de) Verwendung von bis (amidinobenzidazolen) zur herstellung eines medikamentes für die hemmung der retroviral integrase
ATE258789T1 (de) 5-ht2-antagonisten in der behandlung venöser zustände
ATE289816T1 (de) Verwendung von mirtazapine zur herstellung eines medikaments zur behandlung von schlafapnoen
DE58906814D1 (de) Verwendung von ACE-Inhibitoren gegen Neointimabildung nach Gefässverletzung.
ATE212845T1 (de) Verwendung von cytochrome - p 450 - inhibitoren zur hemmung des stoffwechsels von stickstoffsubstituierten acridinen
ATE264674T1 (de) Verwendung von hyaluronsäure zur behandlung der bestrahlungs-blasenentzündung
ATE234613T1 (de) Verwendung von comt inhibitoren zur herstellung eines arzneimittels zur vorbeugung von diabetischen vaskulären funktionsstörungen
GR3021171T3 (en) Use of hyaluronic acid and forms to prevent arterial restenosis.
ES2101100T3 (es) Un producto para el tratamiento del cancer de higado y su procedimiento de manufactura.
EP0929306A4 (de) Verfahren zur hemmung der vermehrung der glatten muskelzellen
UA26438A (uk) СПОСІБ ОТРИМАHHЯ СУЛЬФОHІЛФЕHІЛ- БЕttА-D-ТІОКСИЛОЗИДІВ
ATE324905T1 (de) Verwendung von plgf zur vorbeugung oder behandlung von ischaemie oder schlaganfall
IT1255389B (it) Idrossiammidi della biotina un processo per la loro preparazione e composizioni terapeutiche che li contengono come principi attivi per il trattamento del diabete e delle relative complicanze

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties