ATE194603T1 - Ein verfahren zur herstellung von tetrazolyl- verbindungen - Google Patents

Ein verfahren zur herstellung von tetrazolyl- verbindungen

Info

Publication number
ATE194603T1
ATE194603T1 AT95101055T AT95101055T ATE194603T1 AT E194603 T1 ATE194603 T1 AT E194603T1 AT 95101055 T AT95101055 T AT 95101055T AT 95101055 T AT95101055 T AT 95101055T AT E194603 T1 ATE194603 T1 AT E194603T1
Authority
AT
Austria
Prior art keywords
producing
tetrazolyl compounds
tetrazolyl compound
tetrazolyl
compounds
Prior art date
Application number
AT95101055T
Other languages
English (en)
Inventor
Yasushi Shida
Kokichi Yoshida
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Application granted granted Critical
Publication of ATE194603T1 publication Critical patent/ATE194603T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT95101055T 1994-01-28 1995-01-26 Ein verfahren zur herstellung von tetrazolyl- verbindungen ATE194603T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP823394 1994-01-28

Publications (1)

Publication Number Publication Date
ATE194603T1 true ATE194603T1 (de) 2000-07-15

Family

ID=11687442

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95101055T ATE194603T1 (de) 1994-01-28 1995-01-26 Ein verfahren zur herstellung von tetrazolyl- verbindungen

Country Status (9)

Country Link
US (2) US5578733A (de)
EP (1) EP0668272B1 (de)
AT (1) ATE194603T1 (de)
CA (1) CA2141175C (de)
DE (1) DE69517832T2 (de)
DK (1) DK0668272T3 (de)
ES (1) ES2147798T3 (de)
GR (1) GR3034464T3 (de)
PT (1) PT668272E (de)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2430934C (en) 2000-12-01 2011-06-21 Takeda Chemical Industries, Ltd. A method of producing sustained-release preparations of a bioactive substance using high-pressure gas
US7812044B2 (en) 2001-11-13 2010-10-12 Takeda Pharmaceutical Company Limited Anticancer agents
WO2003074008A2 (en) * 2002-03-01 2003-09-12 Merck & Co., Inc. Aminoalkylphosphonates and related compounds as edg receptor agonists
ES2238022T3 (es) * 2003-03-17 2008-11-01 Teva Pharmaceutical Industries Ltd. Poliformos de valsartan.
WO2004085426A1 (en) * 2003-03-27 2004-10-07 Hetero Drugs Limited Novel crystalline forms of candesartan cilexetil
EP1556363A2 (de) 2003-04-21 2005-07-27 Teva Pharmaceutical Industries Limited Verfahren zur herstellung von valsartan und zwischenprodukte davon
CZ297016B6 (cs) * 2003-08-27 2006-08-16 Zentiva, A.S. Zpusob odstranování trifenylmethanové chránicí skupiny z 1-trityl-5-(4'-subst. aminomethyl-1,1' -bifenyl-2-yl)-1H-tetrazolu a zpusob výroby draselné soli losartanu, irbesartanu a valsartanu s jeho pouzitím
US7098342B2 (en) * 2003-10-16 2006-08-29 Teva Pharmaceutical Industries Ltd. Preparation of candesartan cilexetil
WO2005051928A1 (en) * 2003-11-28 2005-06-09 Ranbaxy Laboratories Limited Process for production of tetrazolyl compounds
WO2005077941A2 (en) 2004-02-11 2005-08-25 Teva Pharmaceutical Industries Ltd. Candesartan cilexetil polymorphs
KR100908308B1 (ko) * 2004-05-05 2009-07-17 테바 파마슈티컬 인더스트리즈 리미티드 순도가 높은 칸데사르탄 실렉세틸의 제조
WO2005123720A1 (en) * 2004-06-18 2005-12-29 Ranbaxy Laboratories Limited Fine particles of the angiotensin ii antagonist candesartan cilexetil and process for production thereof
EP1655298A1 (de) * 2004-11-03 2006-05-10 LEK Pharmaceuticals d.d. Krystalline Polymorpheme Formen von Candesartan Cilexetil
WO2006050922A1 (en) * 2004-11-11 2006-05-18 Lek Pharmaceuticals D.D. Process for the synthesis of tetrazoles
KR20070088783A (ko) * 2005-01-14 2007-08-29 테바 파마슈티컬 인더스트리즈 리미티드 조 칸데사르탄 실렉세틸의 제조
EP2210888B1 (de) * 2005-05-10 2013-04-24 Teva Pharmaceutical Industries, Ltd. Stabiles mikronisiertes Candesartan-Cilexetil und Herstellungsverfahren
WO2007074399A2 (en) 2005-06-06 2007-07-05 Medichem, S.A. Process for the preparation of tetrazolyl compounds
EP1910343B1 (de) * 2005-07-29 2014-10-29 Krka Verfahren zur herstellung von olmesartan-medoxomil
EP1816131A1 (de) * 2006-02-06 2007-08-08 KRKA, tovarna zdravil, d.d., Novo mesto Verfahren zur Herstellung von Olmesartan Medoxomil
SI22127A (sl) 2005-10-07 2007-04-30 Krka, Tovarna Zdravil, D.D., Novo Mesto Postopek za pripravo kandesartan cileksetila
CZ299265B6 (cs) * 2005-10-20 2008-05-28 Zentiva, A. S. Zpusob výroby 1-(cyklohexyloxykarbonyloxy)ethyl-2-ethoxy-1-[[2'-(1H-tetrazol-5-yl)bifenyl-4-yl]methyl]benzimidazol-7-karboxylátu (candesartan cilexetilu)
ITTO20060560A1 (it) * 2006-07-27 2008-01-28 S I M S S R L Composti intermedi per la preparazione di antagonisti dell¿angiotensina ii
WO2008012371A1 (en) * 2006-07-28 2008-01-31 Krka, Tovarna Zdravil, D.D., Novo Mesto Process for the preparation of amorphous and crystalline forms of candesartan cilexetil using column chromatography
EP2170868A1 (de) * 2007-07-11 2010-04-07 Alembic Limited Verbessertes verfahren zur herstellung von candesartancilexetil
CA2762846A1 (en) 2009-05-20 2010-11-25 Ranbaxy Laboratories Limited Process for the preparation of olmesartan medoxomil
WO2011080684A1 (en) 2009-12-31 2011-07-07 Ranbaxy Laboratories Limited Process for the preparation of candesartan cilexetil
WO2011092666A1 (en) 2010-01-29 2011-08-04 Ranbaxy Laboratories Limited An improved process for the preparation of candesartan cilexetil, polymorphic forms of n-trityl candesartan and their uses thereof
KR101251741B1 (ko) 2010-12-16 2013-04-05 동화약품주식회사 칸데사르탄실렉세틸의 개선된 제조방법
CN103396408A (zh) * 2013-08-13 2013-11-20 河南华商药业有限公司 坎地沙坦酯中杂质b的制备方法
CN109851612A (zh) * 2019-01-30 2019-06-07 浙江省食品药品检验研究院 一种坎地沙坦酯晶体及其制备方法
CN109627234A (zh) * 2019-01-30 2019-04-16 浙江省食品药品检验研究院 一种坎地沙坦酯晶体及其制备方法
CN109776503A (zh) * 2019-01-30 2019-05-21 浙江省食品药品检验研究院 一种坎地沙坦酯晶体及其制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4820843A (en) * 1987-05-22 1989-04-11 E. I. Du Pont De Nemours And Company Tetrazole intermediates to antihypertensive compounds
US5196444A (en) * 1990-04-27 1993-03-23 Takeda Chemical Industries, Ltd. 1-(cyclohexyloxycarbonyloxy)ethyl 2-ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]benzimidazole-7-carboxylate and compositions and methods of pharmaceutical use thereof
GB9017480D0 (en) * 1990-08-09 1990-09-26 Ici Plc Chemical process
TW209213B (de) * 1991-08-21 1993-07-11 Yamanouchi Pharma Co Ltd
IL103020A (en) * 1991-09-10 1998-10-30 Tanabe Seiyaku Co 3-(1,1'-Biphenyl-4-yl-methyl)-4,5,6,7-tetrahydro-3h-imidazo Ú4,5-c¾ pyridine-4-carboxylic acids their preparation and pharmaceutical compositions containing them
DE4132632A1 (de) * 1991-10-01 1993-04-08 Bayer Ag Substituierte imidazolyl-propensaeurederivate
EP0550313A1 (de) * 1991-12-30 1993-07-07 Synthelabo 2-(Tetranol-5-yl)-(1,1'-Biphenyl)derivate, ihre Herstellung und Anwendung als Zwischenverbindungen
DE4212748A1 (de) * 1992-04-16 1993-10-21 Thomae Gmbh Dr K Benzimidazole, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung

Also Published As

Publication number Publication date
GR3034464T3 (en) 2000-12-29
EP0668272B1 (de) 2000-07-12
CA2141175C (en) 2006-12-12
EP0668272A3 (de) 1995-08-30
ES2147798T3 (es) 2000-10-01
US5578733A (en) 1996-11-26
PT668272E (pt) 2000-10-31
DE69517832T2 (de) 2000-11-09
CA2141175A1 (en) 1995-07-29
DK0668272T3 (da) 2000-09-18
DE69517832D1 (de) 2000-08-17
US5763619A (en) 1998-06-09
EP0668272A2 (de) 1995-08-23

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