DK0668272T3 - Fremgangsmåde til fremstilling af tetrazolylforbindelser - Google Patents

Fremgangsmåde til fremstilling af tetrazolylforbindelser

Info

Publication number
DK0668272T3
DK0668272T3 DK95101055T DK95101055T DK0668272T3 DK 0668272 T3 DK0668272 T3 DK 0668272T3 DK 95101055 T DK95101055 T DK 95101055T DK 95101055 T DK95101055 T DK 95101055T DK 0668272 T3 DK0668272 T3 DK 0668272T3
Authority
DK
Denmark
Prior art keywords
preparation
tetrazolyl compound
tetrazolyl compounds
tetrazolyl
protected
Prior art date
Application number
DK95101055T
Other languages
English (en)
Inventor
Yasushi Shida
Kokichi Yoshida
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Application granted granted Critical
Publication of DK0668272T3 publication Critical patent/DK0668272T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK95101055T 1994-01-28 1995-01-26 Fremgangsmåde til fremstilling af tetrazolylforbindelser DK0668272T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP823394 1994-01-28

Publications (1)

Publication Number Publication Date
DK0668272T3 true DK0668272T3 (da) 2000-09-18

Family

ID=11687442

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95101055T DK0668272T3 (da) 1994-01-28 1995-01-26 Fremgangsmåde til fremstilling af tetrazolylforbindelser

Country Status (9)

Country Link
US (2) US5578733A (da)
EP (1) EP0668272B1 (da)
AT (1) ATE194603T1 (da)
CA (1) CA2141175C (da)
DE (1) DE69517832T2 (da)
DK (1) DK0668272T3 (da)
ES (1) ES2147798T3 (da)
GR (1) GR3034464T3 (da)
PT (1) PT668272E (da)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2430934C (en) 2000-12-01 2011-06-21 Takeda Chemical Industries, Ltd. A method of producing sustained-release preparations of a bioactive substance using high-pressure gas
US7812044B2 (en) 2001-11-13 2010-10-12 Takeda Pharmaceutical Company Limited Anticancer agents
AU2003218056A1 (en) * 2002-03-01 2003-09-16 Merck & Co., Inc. Aminoalkylphosphonates and related compounds as edg receptor agonists
ES2238022T3 (es) * 2003-03-17 2008-11-01 Teva Pharmaceutical Industries Ltd. Poliformos de valsartan.
US7504516B2 (en) 2003-03-27 2009-03-17 Hetero Drugs Limited Crystalline forms of candesartan cilexetil
WO2004094391A2 (en) 2003-04-21 2004-11-04 Teva Pharmaceutical Industries Ltd. Process for the preparation of valsartan and intermediates thereof
CZ297016B6 (cs) * 2003-08-27 2006-08-16 Zentiva, A.S. Zpusob odstranování trifenylmethanové chránicí skupiny z 1-trityl-5-(4'-subst. aminomethyl-1,1' -bifenyl-2-yl)-1H-tetrazolu a zpusob výroby draselné soli losartanu, irbesartanu a valsartanu s jeho pouzitím
US7098342B2 (en) * 2003-10-16 2006-08-29 Teva Pharmaceutical Industries Ltd. Preparation of candesartan cilexetil
WO2005051928A1 (en) * 2003-11-28 2005-06-09 Ranbaxy Laboratories Limited Process for production of tetrazolyl compounds
WO2005077941A2 (en) 2004-02-11 2005-08-25 Teva Pharmaceutical Industries Ltd. Candesartan cilexetil polymorphs
US20050250827A1 (en) * 2004-05-05 2005-11-10 Etinger Marina Y Preparation of candesartan cilexetil in high purity
WO2005123720A1 (en) * 2004-06-18 2005-12-29 Ranbaxy Laboratories Limited Fine particles of the angiotensin ii antagonist candesartan cilexetil and process for production thereof
EP1655298A1 (en) * 2004-11-03 2006-05-10 LEK Pharmaceuticals d.d. Novel polymorph forms of candesartan cilexetil
WO2006050922A1 (en) * 2004-11-11 2006-05-18 Lek Pharmaceuticals D.D. Process for the synthesis of tetrazoles
US20060194858A1 (en) * 2005-01-14 2006-08-31 Omer Malachi Preparation of crude candesartan cilexetil
ES2429941T3 (es) * 2005-05-10 2013-11-18 Teva Pharmaceutical Industries, Ltd. Candesartán cilexetilo micronizado estable y métodos para preparar el mismo
AR053517A1 (es) 2005-06-06 2007-05-09 Medichem Sa Proceso para la preparacion de compuestos de tetrazolilo, uso de los mismos en el tratamiento de enfermedades circulatorias y formulaciones farmaceuticas que los contienen.
EP1816131A1 (en) * 2006-02-06 2007-08-08 KRKA, tovarna zdravil, d.d., Novo mesto Process for the preparation of olmesartan medoxomil
EP1910343B1 (en) * 2005-07-29 2014-10-29 Krka Process for the preparation of olmesartan medoxomil
SI22127A (sl) 2005-10-07 2007-04-30 Krka, Tovarna Zdravil, D.D., Novo Mesto Postopek za pripravo kandesartan cileksetila
CZ299265B6 (cs) * 2005-10-20 2008-05-28 Zentiva, A. S. Zpusob výroby 1-(cyklohexyloxykarbonyloxy)ethyl-2-ethoxy-1-[[2'-(1H-tetrazol-5-yl)bifenyl-4-yl]methyl]benzimidazol-7-karboxylátu (candesartan cilexetilu)
ITTO20060560A1 (it) * 2006-07-27 2008-01-28 S I M S S R L Composti intermedi per la preparazione di antagonisti dell¿angiotensina ii
EP2066649A1 (en) * 2006-07-28 2009-06-10 KRKA, tovarna zdravil, d.d., Novo mesto Process for the preparation of amorphous and crystalline forms of candesartan cilexetil using column chromatography
CA2693513A1 (en) * 2007-07-11 2009-01-15 Alembic Limited An improved process for the preparation of candesartan cilexetil
EA201171413A1 (ru) 2009-05-20 2012-09-28 Ранбакси Лабораториз Лимитед Способ получения олмесартана медоксомила
WO2011080684A1 (en) 2009-12-31 2011-07-07 Ranbaxy Laboratories Limited Process for the preparation of candesartan cilexetil
WO2011092666A1 (en) 2010-01-29 2011-08-04 Ranbaxy Laboratories Limited An improved process for the preparation of candesartan cilexetil, polymorphic forms of n-trityl candesartan and their uses thereof
KR101251741B1 (ko) 2010-12-16 2013-04-05 동화약품주식회사 칸데사르탄실렉세틸의 개선된 제조방법
CN103396408A (zh) * 2013-08-13 2013-11-20 河南华商药业有限公司 坎地沙坦酯中杂质b的制备方法
CN109627234A (zh) * 2019-01-30 2019-04-16 浙江省食品药品检验研究院 一种坎地沙坦酯晶体及其制备方法
CN109851612A (zh) * 2019-01-30 2019-06-07 浙江省食品药品检验研究院 一种坎地沙坦酯晶体及其制备方法
CN109776503A (zh) * 2019-01-30 2019-05-21 浙江省食品药品检验研究院 一种坎地沙坦酯晶体及其制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4820843A (en) * 1987-05-22 1989-04-11 E. I. Du Pont De Nemours And Company Tetrazole intermediates to antihypertensive compounds
US5196444A (en) * 1990-04-27 1993-03-23 Takeda Chemical Industries, Ltd. 1-(cyclohexyloxycarbonyloxy)ethyl 2-ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]benzimidazole-7-carboxylate and compositions and methods of pharmaceutical use thereof
GB9017480D0 (en) * 1990-08-09 1990-09-26 Ici Plc Chemical process
TW209213B (da) * 1991-08-21 1993-07-11 Yamanouchi Pharma Co Ltd
EP0531874A1 (en) * 1991-09-10 1993-03-17 Tanabe Seiyaku Co., Ltd. Imidazopyridine derivatives and process for preparation thereof
DE4132632A1 (de) * 1991-10-01 1993-04-08 Bayer Ag Substituierte imidazolyl-propensaeurederivate
EP0550313A1 (fr) * 1991-12-30 1993-07-07 Synthelabo Nouveaux dérivés de 2-(tétrazol-5-yl)-(1,1'-biphényle), leur préparation et leur utilisation comme intermédiaires de synthèse
DE4212748A1 (de) * 1992-04-16 1993-10-21 Thomae Gmbh Dr K Benzimidazole, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung

Also Published As

Publication number Publication date
US5578733A (en) 1996-11-26
EP0668272B1 (en) 2000-07-12
GR3034464T3 (en) 2000-12-29
DE69517832T2 (de) 2000-11-09
EP0668272A3 (en) 1995-08-30
DE69517832D1 (de) 2000-08-17
US5763619A (en) 1998-06-09
CA2141175A1 (en) 1995-07-29
EP0668272A2 (en) 1995-08-23
ATE194603T1 (de) 2000-07-15
CA2141175C (en) 2006-12-12
PT668272E (pt) 2000-10-31
ES2147798T3 (es) 2000-10-01

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