ATE195420T1 - Methode zur herstellung von eicosapentansäuren - Google Patents

Methode zur herstellung von eicosapentansäuren

Info

Publication number
ATE195420T1
ATE195420T1 AT91907423T AT91907423T ATE195420T1 AT E195420 T1 ATE195420 T1 AT E195420T1 AT 91907423 T AT91907423 T AT 91907423T AT 91907423 T AT91907423 T AT 91907423T AT E195420 T1 ATE195420 T1 AT E195420T1
Authority
AT
Austria
Prior art keywords
diatoms
epa
pct
producing
depletion
Prior art date
Application number
AT91907423T
Other languages
English (en)
Inventor
David John Kyle
Raymond Gladue
Original Assignee
Martek Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Martek Corp filed Critical Martek Corp
Application granted granted Critical
Publication of ATE195420T1 publication Critical patent/ATE195420T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409—Fatty acids
    • C12P7/6427—Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
    • C12P7/6432—Eicosapentaenoic acids [EPA]
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/158—Fatty acids; Fats; Products containing oils or fats
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/80—Feeding-stuffs specially adapted for particular animals for aquatic animals, e.g. fish, crustaceans or molluscs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/02—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
    • C07C57/03—Monocarboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/12—Unicellular algae; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436—Fatty acid esters
    • C12P7/6445—Glycerides
    • C12P7/6472—Glycerides containing polyunsaturated fatty acid [PUFA] residues, i.e. having two or more double bonds in their backbone

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Polymers & Plastics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Food Science & Technology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Animal Husbandry (AREA)
  • Medicinal Chemistry (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Botany (AREA)
  • Cell Biology (AREA)
  • Biomedical Technology (AREA)
  • Birds (AREA)
  • Insects & Arthropods (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Fats And Perfumes (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
AT91907423T 1990-03-21 1991-03-20 Methode zur herstellung von eicosapentansäuren ATE195420T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/496,572 US5244921A (en) 1990-03-21 1990-03-21 Eicosapentaenoic acids and methods for their production
PCT/US1991/002052 WO1991014427A1 (en) 1990-03-21 1991-03-20 Eicosapentaenoic acids and methods for their production

Publications (1)

Publication Number Publication Date
ATE195420T1 true ATE195420T1 (de) 2000-09-15

Family

ID=23973229

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91907423T ATE195420T1 (de) 1990-03-21 1991-03-20 Methode zur herstellung von eicosapentansäuren

Country Status (7)

Country Link
US (2) US5244921A (de)
EP (1) EP0521104B1 (de)
JP (1) JPH05505726A (de)
AT (1) ATE195420T1 (de)
CA (1) CA2078664A1 (de)
DE (1) DE69132370T2 (de)
WO (1) WO1991014427A1 (de)

Families Citing this family (79)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060094089A1 (en) * 1988-09-07 2006-05-04 Martek Biosciences Corporation Process for the heterotrophic production of microbial products with high concentrations of omega-3 highly unsaturated fatty acids
US5985348A (en) * 1995-06-07 1999-11-16 Omegatech, Inc. Milk products having high concentrations of omega-3 highly unsaturated fatty acids
US6451567B1 (en) 1988-09-07 2002-09-17 Omegatech, Inc. Fermentation process for producing long chain omega-3 fatty acids with euryhaline microorganisms
US5340742A (en) 1988-09-07 1994-08-23 Omegatech Inc. Process for growing thraustochytrium and schizochytrium using non-chloride salts to produce a microfloral biomass having omega-3-highly unsaturated fatty acids
ES2157898T3 (es) 1991-01-24 2001-09-01 Martek Corp Aceites microbianos y usos de los mismos.
US6410281B1 (en) 1992-07-10 2002-06-25 Omegatech, Inc. Reducing corrosion in a fermentor by providing sodium with a non-chloride sodium salt
US6255505B1 (en) 1996-03-28 2001-07-03 Gist-Brocades, B.V. Microbial polyunsaturated fatty acid containing oil from pasteurised biomass
JP3096654B2 (ja) * 1997-04-01 2000-10-10 クロレラ工業株式会社 高度不飽和脂肪酸含有クロレラの製造方法
MXPA01001750A (es) * 1998-08-18 2002-04-08 Metabolix Inc Productos microbianos transgenicos de polihidroxialcanoato.
US6166231A (en) * 1998-12-15 2000-12-26 Martek Biosciences Corporation Two phase extraction of oil from biomass
GB9916537D0 (en) * 1999-07-14 1999-09-15 Univ Hull Culture of microorganisms for the synthesis of a polyunsaturated fatty acid
CN105112463A (zh) * 2000-01-28 2015-12-02 Dsmip资产公司 通过在发酵罐中高密度培养真核微生物来增加含有多烯脂肪酸的脂质的产生
EP1780283A1 (de) 2000-04-21 2007-05-02 Martek Biosciences Corporation Trophische Umwandlung von obligat phototropischen Algen durch metabolische Manipulation
AU2001253699B2 (en) 2000-04-21 2006-04-27 Martek Biosciences Corporation Trophic conversion of obligate phototrophic algae through metabolic engineering
GB2377455A (en) * 2001-02-09 2003-01-15 Univ Hull Method of culturing crypthecodinium cohnii
FR2822701B1 (fr) * 2001-04-03 2005-03-18 Lvmh Rech Utilisation d'un extrait d'algue phaeodactylum comme agent cosmetique favorisant l'activite du proteasome des cellules de la peau et composition cosmetique le contenant
GB0113348D0 (en) * 2001-06-01 2001-07-25 Mars Uk Ltd Skin diet
EP1304029A1 (de) 2001-10-19 2003-04-23 Dsm N.V. Polyungesättigte Fettsäuren in Eier
CA3030068C (en) 2002-06-19 2022-09-13 Dsm Ip Assets B.V. Pasteurisation process for microbial cells and microbial oil
CA2395622A1 (fr) * 2002-07-22 2004-01-22 Edwin Bourget Procede d'enrichissement en lipides et en acides gras omega-3 dans les cultures d'algues
GB0301701D0 (en) * 2003-01-24 2003-02-26 Ensay Ltd Psoriasis and Eicosapentaenoic acid
US7238482B2 (en) * 2003-05-07 2007-07-03 E. I. Du Pont De Nemours And Company Production of polyunsaturated fatty acids in oleaginous yeasts
US20070015263A1 (en) * 2003-09-01 2007-01-18 Mogens Wumpelmann Method for increasing yield of biomass of and/or components of biomass from marine microorganisms
EP1833313A2 (de) * 2004-10-15 2007-09-19 Corporation Limited Photonz Zusammensetzungen mit hohem omega-3-fettsäuregehalt und niedrigem gesättigten fettsäuregehalt
US7588931B2 (en) 2004-11-04 2009-09-15 E. I. Du Pont De Nemours And Company High arachidonic acid producing strains of Yarrowia lipolytica
US7198937B2 (en) * 2004-11-04 2007-04-03 E. I. Du Pont De Nemours And Company Mortierella alpina diacylglycerol acyltransferase for alteration of polyunsaturated fatty acids and oil content in oleaginous organisms
US8685679B2 (en) * 2004-11-04 2014-04-01 E I Du Pont De Nemours And Company Acyltransferase regulation to increase the percent of polyunsaturated fatty acids in total lipids and oils of oleaginous organisms
DK2447356T3 (en) 2005-06-07 2016-06-06 Dsm Nutritional Products Ag Eukaryotic MICROORGANISMS FOR PRODUCTION OF LIPIDS AND ANTIOXIDANTS
GB0604647D0 (en) 2006-03-08 2006-04-19 Shchepinov Mikhail Stabilized food supplements and their derivatives
JP5242949B2 (ja) * 2006-05-31 2013-07-24 独立行政法人水産総合研究センター 藻類へのケイ酸成分供給方法
US9162953B2 (en) * 2006-07-05 2015-10-20 Centre Nationale De Recherche Scientifique Iron-copper co-catalyzed process for carbon-carbon or carbon-heteroatom bonding
NZ573719A (en) * 2006-07-05 2011-08-26 Photonz Corp Ltd Production of ultrapure eicosapentaenoic acid and polar lipids from largely heterotrophic culture of nitzschia laevis
WO2008129358A2 (en) 2006-08-01 2008-10-30 Ocean Nutrition Canada Ltd. Oil producing microbes and methods of modification thereof
KR20090092758A (ko) * 2006-09-18 2009-09-01 더 아리조나 보드 오브 리전트스, 어 바디 코포레이트 액팅 포 앤드 온 비핼프 오브 아리조나 스테이트 유니버시티 조류 중쇄 길이 지방산 및 탄화수소
US8088614B2 (en) * 2006-11-13 2012-01-03 Aurora Algae, Inc. Methods and compositions for production and purification of biofuel from plants and microalgae
US8221743B2 (en) 2006-12-22 2012-07-17 Novozymes A/S Use of polypeptides against diseases caused by protozoans
JP5711968B2 (ja) 2007-10-03 2015-05-07 イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニーＥ．Ｉ．Ｄｕ Ｐｏｎｔ Ｄｅ Ｎｅｍｏｕｒｓ Ａｎｄ Ｃｏｍｐａｎｙ 高エイコサペンタエン酸を生成するためのヤロウィア・リポリティカ（ＹａｒｒｏｗｉａＬｉｐｏｌｙｔｉｃａ）の最適化株
US8343753B2 (en) * 2007-11-01 2013-01-01 Wake Forest University School Of Medicine Compositions, methods, and kits for polyunsaturated fatty acids from microalgae
US20100303989A1 (en) 2008-10-14 2010-12-02 Solazyme, Inc. Microalgal Flour
US8207363B2 (en) 2009-03-19 2012-06-26 Martek Biosciences Corporation Thraustochytrids, fatty acid compositions, and methods of making and uses thereof
KR101615409B1 (ko) * 2009-04-10 2016-04-25 일렉트릭 파워 디벨롭먼트 컴퍼니 리미티드 나비큘라속에 속하는 미세 조류, 그 미세 조류의 배양에 의한 유분의 제조 방법, 및 그 미세 조류로부터 채취한 유분
KR101769121B1 (ko) * 2009-04-14 2017-08-17 테라비아 홀딩스 인코포레이티드 신규의 미세 조류 식품 조성물
US8865452B2 (en) * 2009-06-15 2014-10-21 Aurora Algae, Inc. Systems and methods for extracting lipids from wet algal biomass
US9101942B2 (en) * 2009-06-16 2015-08-11 Aurora Algae, Inc. Clarification of suspensions
US8747930B2 (en) * 2009-06-29 2014-06-10 Aurora Algae, Inc. Siliceous particles
US8765983B2 (en) * 2009-10-30 2014-07-01 Aurora Algae, Inc. Systems and methods for extracting lipids from and dehydrating wet algal biomass
BR122015020119B8 (pt) 2010-01-19 2021-05-04 Dsm Ip Assets Bv óleo microbiano, produtos alimentícios para um animal não humano e biomassa isolada
JP5865894B2 (ja) * 2010-04-14 2016-02-17 ソラザイム ロケット ニュートリショナルズ， エルエルシー 高脂質微細藻類粉末食品組成物
EP2561050A1 (de) 2010-04-22 2013-02-27 E.I. Du Pont De Nemours And Company Verfahren zur gewinnung von mehrfach ungesättigten säurehaltigen zusammensetzungen aus mikrobieller biomasse
US8769868B2 (en) 2010-06-09 2014-07-08 Photonz Corporation Limited Compositions comprising eicosapentaenoic acid suitable for high purification
MY163938A (en) 2010-06-14 2017-11-15 Io-Mega Holding Corp Method for the production of algae derived oils
US20120040076A1 (en) 2010-08-11 2012-02-16 E. I. Du Pont De Nemours And Company Aquaculture feed compositions
EP2603094A1 (de) 2010-08-11 2013-06-19 E.I. Du Pont De Nemours And Company Nachhaltige aquakulturfütterung
US20120207912A1 (en) 2010-08-11 2012-08-16 E.I. Du Pont De Nemours And Company Aquaculture meat products
CN103249834B (zh) 2010-08-26 2016-10-26 纳幕尔杜邦公司 生产高水平二十碳五烯酸的重组微生物宿主细胞
NZ588781A (en) * 2010-10-22 2013-08-30 Photonz Corp Ltd Method of provision of silicate to culture media
US8926844B2 (en) 2011-03-29 2015-01-06 Aurora Algae, Inc. Systems and methods for processing algae cultivation fluid
US8569530B2 (en) 2011-04-01 2013-10-29 Aurora Algae, Inc. Conversion of saponifiable lipids into fatty esters
MX339607B (es) 2011-05-06 2016-05-31 Solazyme Inc Microorganismos geneticamente modificados que metabolizan xilosa.
WO2013013211A1 (en) 2011-07-21 2013-01-24 Dsm Ip Assets B.V. Fatty acid compositions
SG10201709538QA (en) 2012-12-24 2017-12-28 Qualitas Health Ltd Eicosapentaenoic acid (epa) formulations
US10098371B2 (en) 2013-01-28 2018-10-16 Solazyme Roquette Nutritionals, LLC Microalgal flour
JP6300220B2 (ja) * 2013-03-04 2018-03-28 国立大学法人山口大学 微細藻類を用いた脂質の製造方法
EP2970926B1 (de) 2013-03-13 2018-01-31 DSM Nutritional Products AG Manipulation von mikroorganismen
US9266973B2 (en) 2013-03-15 2016-02-23 Aurora Algae, Inc. Systems and methods for utilizing and recovering chitosan to process biological material
EP2826384A1 (de) 2013-07-16 2015-01-21 Evonik Industries AG Verfahren zur Trocknung von Biomasse
US9879218B2 (en) 2013-08-01 2018-01-30 Fermentalg Methods for the production of diatom biomass
FR3009619B1 (fr) 2013-08-07 2017-12-29 Roquette Freres Compositions de biomasse de microalgues riches en proteines de qualite sensorielle optimisee
EP3200604B2 (de) 2014-10-02 2025-05-07 Evonik Operations GmbH Verfahren zur herstellung eines futtermittels
BR112017006838B1 (pt) 2014-10-02 2021-07-06 Evonik Operations Gmbh Processo para produzir um alimento para animais compreendendo biomassa contendo pufa, alimento para animais e método para criar animais
US11464244B2 (en) 2014-10-02 2022-10-11 Evonik Operations Gmbh Feedstuff of high abrasion resistance and good stability in water, containing PUFAs
EP3200606B1 (de) 2014-10-02 2021-03-31 Evonik Operations GmbH Verfahren zur herstellung eines pufas enthaltenden futtermittels durch extrusion einer pufas enthaltenden biomasse des typs labyrinthulomycetes
AR104042A1 (es) 2015-03-26 2017-06-21 Mara Renewables Corp Producción de alta densidad de biomasa y aceite utilizando glicerol en bruto
AU2016293487B2 (en) 2015-07-13 2021-07-01 MARA Renewables Corporation Enhancing microalgal metabolism of xylose
JP6625370B2 (ja) * 2015-08-24 2019-12-25 岡山県 藻類の培養密度を向上させるための組成物およびその利用
US10851395B2 (en) 2016-06-10 2020-12-01 MARA Renewables Corporation Method of making lipids with improved cold flow properties
RU2661116C1 (ru) * 2017-12-13 2018-07-11 Общество с ограниченной ответственностью "СОЛИКСАНТ" Штамм одноклеточной микроводоросли Eustigmatos magnus - продуцент эйкозапентаеновой кислоты
NO20201076A1 (en) 2020-10-01 2022-04-04 Finnfjord As Process for cultivation of diatoms
CN121021291B (zh) * 2025-10-29 2026-02-03 湖北藻蓝生物科技有限公司 一种从三角褐指藻中综合提取含epa和ara的类二十烷酸方法和应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2725677A (en) * 1952-01-16 1955-12-06 Carnegie Inst Of Washington Method of effectuating high density mass culture of algae or other microorganisms
US4670285A (en) * 1982-08-06 1987-06-02 The University Of Toronto Innovations Foundation Infant formula
JPS5946225A (ja) * 1982-09-09 1984-03-15 Kogyo Kaihatsu Kenkyusho 抗動脈硬化剤の製造方法
JPS6034156A (ja) * 1983-08-08 1985-02-21 Hayashibara Biochem Lab Inc エイコサペンタエン酸包接化合物及びこれを含有した飲食物
JPS60133094A (ja) * 1983-12-21 1985-07-16 日清製油株式会社 高純度エイコサペンタエン酸の製造法
JPS63185390A (ja) * 1987-01-27 1988-07-30 Suntory Ltd 藻類によるエイコサペンタエン酸の製造方法
AU2122688A (en) * 1987-07-20 1989-02-13 Maricultura, Incorporated Microorganism production of omega-3 (n-3) lipids

Also Published As

Publication number Publication date
JPH05505726A (ja) 1993-08-26
EP0521104B1 (de) 2000-08-16
EP0521104A1 (de) 1993-01-07
DE69132370T2 (de) 2001-03-29
CA2078664A1 (en) 1991-09-22
US5244921A (en) 1993-09-14
WO1991014427A1 (en) 1991-10-03
US5567732A (en) 1996-10-22
EP0521104A4 (en) 1993-03-24
DE69132370D1 (de) 2000-09-21

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