ATE196846T1 - Ein organisches aminenthaltende pranoprofen- augentropfen - Google Patents

Ein organisches aminenthaltende pranoprofen- augentropfen

Info

Publication number: ATE196846T1
Authority: AT; Austria
Prior art keywords: organic amine; ophthalmic solution; eye drops; amine containing; pranoprofen
Prior art date: 1995-04-20

Application number

AT96909378T

Other languages

English (en)

Inventor

Shogo Miyagi

Chome

Yoshihide Horibe

Original Assignee

Santen Pharmaceutical Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-04-20

Filing date

1996-04-16

Publication date

2000-10-15

1996-04-16 Application filed by Santen Pharmaceutical Co Ltd filed Critical Santen Pharmaceutical Co Ltd

2000-10-15 Application granted granted Critical

2000-10-15 Publication of ATE196846T1 publication Critical patent/ATE196846T1/de

Links

150000001412 amines Chemical class 0.000 title abstract 5
TVQZAMVBTVNYLA-UHFFFAOYSA-N Pranoprofen Chemical compound C1=CC=C2CC3=CC(C(C(O)=O)C)=CC=C3OC2=N1 TVQZAMVBTVNYLA-UHFFFAOYSA-N 0.000 title abstract 4
229960003101 pranoprofen Drugs 0.000 title abstract 4
239000003889 eye drop Substances 0.000 title 1
229940012356 eye drops Drugs 0.000 title 1
229940054534 ophthalmic solution Drugs 0.000 abstract 5
239000002997 ophthalmic solution Substances 0.000 abstract 5
JKMHFZQWWAIEOD-UHFFFAOYSA-N 2-[4-(2-hydroxyethyl)piperazin-1-yl]ethanesulfonic acid Chemical compound OCC[NH+]1CCN(CCS([O-])(=O)=O)CC1 JKMHFZQWWAIEOD-UHFFFAOYSA-N 0.000 abstract 1
239000004480 active ingredient Substances 0.000 abstract 1
229960000686 benzalkonium chloride Drugs 0.000 abstract 1
CADWTSSKOVRVJC-UHFFFAOYSA-N benzyl(dimethyl)azanium;chloride Chemical compound [Cl-].C[NH+](C)CC1=CC=CC=C1 CADWTSSKOVRVJC-UHFFFAOYSA-N 0.000 abstract 1
230000007794 irritation Effects 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
LENZDBCJOHFCAS-UHFFFAOYSA-N tris Chemical group OCC(N)(CO)CO LENZDBCJOHFCAS-UHFFFAOYSA-N 0.000 abstract 1
229960000281 trometamol Drugs 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones

Landscapes

Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Epidemiology (AREA)
Ophthalmology & Optometry (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

AT96909378T 1995-04-20 1996-04-16 Ein organisches aminenthaltende pranoprofen- augentropfen ATE196846T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP09472395A JP3170619B2 (ja)	1995-04-20	1995-04-20	有機アミンを配合したプラノプロフェン点眼液
PCT/JP1996/001035 WO1996032941A1 (en)	1995-04-20	1996-04-16	Pranoprofen eyedrops containing organic amine

Publications (1)

Publication Number	Publication Date
ATE196846T1 true ATE196846T1 (de)	2000-10-15

Family

ID=14118050

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT96909378T ATE196846T1 (de)	1995-04-20	1996-04-16	Ein organisches aminenthaltende pranoprofen- augentropfen

Country Status (10)

Country	Link
US (1)	US6281224B1 (de)
EP (1)	EP0824916B1 (de)
JP (1)	JP3170619B2 (de)
AT (1)	ATE196846T1 (de)
DE (1)	DE69610622T2 (de)
DK (1)	DK0824916T3 (de)
ES (1)	ES2152016T3 (de)
GR (1)	GR3034705T3 (de)
PT (1)	PT824916E (de)
WO (1)	WO1996032941A1 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6274592B1 (en) *	1997-02-04	2001-08-14	Senju Pharmaceutical Co., Ltd.	Method for stabilizing arylcarboxylic acid, stabilizer thereof and aqueous solution containing stabilized arylcarboxylic acid
US20020198174A1 (en) *	2001-05-07	2002-12-26	Allergan Sales, Inc.	Disinfecting and solubilizing steroid compositions
US6211246B1 (en) *	1999-06-10	2001-04-03	Mcneil-Ppc, Inc.	Rapidly absorbed liquid compositions
PT1283042E (pt) *	2000-05-17	2008-11-19	Senju Pharma Co	Preparação líquida aquosa de pranoprofeno
JP4707316B2 (ja) *	2002-10-11	2011-06-22	ロート製薬株式会社	水性液状組成物
WO2005046700A1 (ja) *	2003-11-14	2005-05-26	Senju Pharmaceutical Co., Ltd.	アミノグリコシド系抗生物質およびブロムフェナクを含有する水溶液製剤
JP4789479B2 (ja) *	2004-02-23	2011-10-12	ロート製薬株式会社	プラノプロフェン含有水性組成物
JP2005239681A (ja) *	2004-02-27	2005-09-08	Taisho Pharmaceut Co Ltd	眼科用剤
JP2005239658A (ja) *	2004-02-27	2005-09-08	Taisho Pharmaceut Co Ltd	点眼剤
JP5434981B2 (ja) *	2004-02-27	2014-03-05	大正製薬株式会社	点眼剤
JP4961671B2 (ja) *	2004-02-27	2012-06-27	大正製薬株式会社	点眼剤
JP5785353B2 (ja) *	2004-02-27	2015-09-30	大正製薬株式会社	眼科用剤
WO2006049250A1 (ja)	2004-11-05	2006-05-11	Senju Pharmaceutical Co., Ltd.	眼内移行性促進水性点眼剤
US8030349B2 (en)	2005-08-02	2011-10-04	Santen Pharmaceutical Co., Ltd.	Method for prevention of degradation of thermally unstable medicament
JP5252787B2 (ja) *	2005-08-02	2013-07-31	参天製薬株式会社	熱的に不安定な薬物の分解抑制方法
JP5305710B2 (ja) *	2008-03-31	2013-10-02	株式会社ニデック	ドルゾラミド塩酸塩点眼液
JP5992293B2 (ja) *	2012-10-31	2016-09-14	大正製薬株式会社	眼科用剤
WO2014192738A1 (ja) *	2013-05-30	2014-12-04	千寿製薬株式会社	両性イオン性ソフトコンタクトレンズ用眼科用組成物

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS5195120A (en) *	1975-02-10	1976-08-20		Tenganekino seizoho
JPS5989616A (ja) *	1982-11-15	1984-05-23	Lion Corp	点眼液
JPS5989617A (ja) *	1982-11-15	1984-05-23	Lion Corp	点眼液
JPS60184013A (ja) *	1984-03-01	1985-09-19	Yoshitomi Pharmaceut Ind Ltd	点眼剤
JPS6112617A (ja) *	1984-06-27	1986-01-21	Lion Corp	点眼液
US4696917A (en) *	1985-08-01	1987-09-29	Lindstrom Richard L	Irrigation solution
DE3612537C1 (de)	1986-04-14	1987-07-16	Dispersa Ag	Arzneimittel zur Behandlung von Entzuendungen im Auge
DE3612538A1 (de) *	1986-04-14	1987-10-15	Dispersa Ag	Stabilisierung von quecksilberhaltigen konservierungsmitteln in augentropfen
JPS6429170A (en)	1987-07-24	1989-01-31	Nec Corp	Method and apparatus for recording dot picture
US5414011A (en)	1987-09-11	1995-05-09	Syntex (U.S.A.) Inc.	Preservative system for ophthalmic formulations
EP0501578A1 (de) *	1991-02-28	1992-09-02	Merck Frosst Canada Inc.	Pyranylphenyl-hydroyalkylnaphthalinsäuren als Inhibitoren der Leuktotrien-Biosynthese
JPH05186349A (ja) *	1991-12-30	1993-07-27	Teika Seiyaku Kk	プラノプロフェン点眼剤組成物
JPH0717863A (ja) *	1993-06-30	1995-01-20	Kaken Pharmaceut Co Ltd	プラノプロフェン点眼液
JP3021312B2 (ja) *	1994-03-15	2000-03-15	千寿製薬株式会社	プラノプロフェンの安定化方法および安定なプラノプロフェン水性液剤
JP3297969B2 (ja) *	1994-12-26	2002-07-02	ライオン株式会社	点眼剤

1995
- 1995-04-20 JP JP09472395A patent/JP3170619B2/ja not_active Expired - Lifetime
1996
- 1996-04-16 DE DE69610622T patent/DE69610622T2/de not_active Expired - Fee Related
- 1996-04-16 ES ES96909378T patent/ES2152016T3/es not_active Expired - Lifetime
- 1996-04-16 AT AT96909378T patent/ATE196846T1/de not_active IP Right Cessation
- 1996-04-16 WO PCT/JP1996/001035 patent/WO1996032941A1/ja not_active Ceased
- 1996-04-16 US US08/945,198 patent/US6281224B1/en not_active Expired - Fee Related
- 1996-04-16 PT PT96909378T patent/PT824916E/pt unknown
- 1996-04-16 DK DK96909378T patent/DK0824916T3/da active
- 1996-04-16 EP EP96909378A patent/EP0824916B1/de not_active Expired - Lifetime
2000
- 2000-10-30 GR GR20000402394T patent/GR3034705T3/el not_active IP Right Cessation

Also Published As

Publication number	Publication date
DK0824916T3 (da)	2001-02-05
DE69610622T2 (de)	2001-05-31
ES2152016T3 (es)	2001-01-16
PT824916E (pt)	2001-01-31
EP0824916B1 (de)	2000-10-11
JPH08291065A (ja)	1996-11-05
EP0824916A4 (de)	1999-06-16
EP0824916A1 (de)	1998-02-25
US6281224B1 (en)	2001-08-28
GR3034705T3 (en)	2001-01-31
DE69610622D1 (de)	2000-11-16
JP3170619B2 (ja)	2001-05-28
WO1996032941A1 (en)	1996-10-24

Legal Events

Date	Code	Title	Description
2001-01-15	UEP	Publication of translation of european patent specification
2006-01-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
DE69610622D1 (de)	2000-11-16	Ein organisches aminenthaltende pranoprofen-augentropfen
DK0725779T3 (da)	2001-10-29	Hidtil ukendte (R)-5-Carbamoyl-8-fluor-3-N,N-disubstitueret-amino-3,4-dihydro-2H-1-benzopyraner
BR9714164A (pt)	2000-05-02	Novos derivados de ácido fluoracrìlico, novas misturas de herbicidas e antìdotos e seu emprego
DE69326637D1 (de)	1999-11-11	1,4-Disubstituierte Piperazine zur Behandlung von Erkrankungen des Zentralnervensystems und von nervenendokrinen Erkrankungen
DE69531314D1 (de)	2003-08-21	Verwendung von metallionen chelatoren zur stabilisierung von interferon-enthaltenden pharmazeutischen zubereitungen
RU94038064A (ru)	1997-05-27	Производные пиперазина и пиперидина, их применение в качестве противопсихотических средств, способ их получения фармацевтическая композиция
KR950031062A (ko)	1995-12-18	안압 강하용 점안제
ATE187891T1 (de)	2000-01-15	Ophtalmische zusammensetzungen enthaltend amidoamine
DE59405376D1 (de)	1998-04-09	Eintopfverfahren zur Herstellung von 3-Chinoloncarbonsäurederivaten
EP1130016A4 (de)	2003-01-29	Derivate der thiocarbamat-säure
ES2156155T3 (es)	2001-06-16	Derivado de pirazol.
KR940005274A (ko)	1994-03-21	쇼그렌(Sjoegren)증후군 치료제
ES2123873T3 (es)	1999-01-16	Pirrolocarbazol.
DK0688771T3 (da)	2001-09-17	Anvendelse af lactamforbindelser som farmaceutiske aktivstoffer
FI973060A0 (fi)	1997-07-18	Anti-inflammatorisia silmätippoja
ATE68182T1 (de)	1991-10-15	Thiophensulfonamide zur behandlung von glaukom.
ATE117361T1 (de)	1995-02-15	Verdickte saure flüssigzusammensetzung mit einem aminhaltigen fluoreszierenden weissmacher-agens (fwa), verwendbar als bleichhilfsmittel.
ATE66221T1 (de)	1991-08-15	Substituierte 5-amino-pyrazole und diese enthaltende fungizide.
DE69426433D1 (de)	2001-01-25	2-Hydroxy-3-[1-(1H-imidazol-4-yl)Alkyl]-Benzol Carboximid-Amide zur Glaucoma-Behandlung
ES2095726T3 (es)	1997-02-16	Piperazinas sustituidas, su procedimiento de preparacion y las composiciones farmaceuticas que las contienen.
ES2079530T3 (es)	1996-01-16	1-(piridinilalquil)-1h-indoles, -indolinas y compuestos analogos relacionados.
ATE97403T1 (de)	1993-12-15	Indol-carboxamid-derivate und ihre salze, verfahren und zwischenprodukte zur herstellung, anwendung als heilmittel und zusammenstellungen, die sie enthalten.
DE69733316D1 (de)	2005-06-23	Herstellung von 3-fluoroxindolderivaten
ATE274927T1 (de)	2004-09-15	Zusammensetzungen enthaltend monoperphthalatsäure zur behandlung von kontaktlinsen
DK324987D0 (da)	1987-06-25	3-substituerede 1-(2-halogenalkoxy-benzen-sulfonyl)-3-heteroaryl-(thio)urinstoffer, fremgangsmaader til deres fremstilling samt deres anvendelse som herbicider